MMHCC Repository NCI-Frederick

Available Strain Details

 
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Strain Number: 01XA9 
Common Strain Name: MMTV-Cre, Line F 
Strain Nomenclature: B6.Cg-Tg(MMTV-Cre)22Mam 
 
Release Category (Required for MTA form): C,D
Sample MTA for this strain
   
       
Strain Description: Widespread Cre expression including the female germline. High levels of recombination in the virgin and lactating mammary gland, salivary gland, seminal vesicle, skin and cells of the immune system. Little expression in the lung, kidney, liver and brain.
       
Mutation Information  
  Mutation Type: Transgenic 
  Gene Name:
  Gene Symbol:
  Transgene Name: Cre recombinase
  Transgene Symbol: Cre
  Promoter Name: Mouse mammary tumor virus 
  Promoter Symbol: MMTV 
  Current Genetic Background: B6.Cg 
  Approx. Generation: 20 
  Organ Site : Breast 
       
Cryopreservation Mating Scheme:  
Genotyping Information: Protocol 2: Allele: Tg(MMTV-Cre)22Mam  
       
Donating Investigator: Dr. Lothar  Hennighausen
Key Reference: Wagner KU, Wall RJ, St-Onge L, Gruss P, Wynshaw-Boris A, Garrett L, Li M, Furth PA, Hennighausen L 1997. Cre-mediated gene deletion in the mammary gland. Nucleic Acids Res 25 :4323-4330. [PubMED Abstract]
     
       
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