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Strain
Number: |
01XA9 |
Common
Strain Name: |
MMTV-Cre, Line F |
Strain
Nomenclature: |
B6.Cg-Tg(MMTV-Cre)22Mam |
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Release
Category (Required for MTA form):
C,D
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Strain
Description: |
Widespread Cre expression including the female germline. High levels of recombination in the virgin and lactating mammary gland, salivary gland, seminal vesicle, skin and cells of the immune system. Little expression in the lung, kidney, liver and brain. |
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Mutation
Information |
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Mutation
Type: |
Transgenic |
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Gene
Name: |
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Gene
Symbol: |
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Transgene
Name: |
Cre recombinase
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Transgene
Symbol: |
Cre
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Promoter
Name: |
Mouse mammary tumor virus |
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Promoter
Symbol: |
MMTV |
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Current
Genetic Background: |
B6.Cg |
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Approx.
Generation: |
20 |
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Organ
Site : |
Breast |
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Cryopreservation Mating Scheme: |
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Genotyping Information: |
Protocol 2: Allele: Tg(MMTV-Cre)22Mam
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Donating
Investigator: |
Dr. Lothar Hennighausen |
Key
Reference: |
Wagner KU, Wall RJ, St-Onge L, Gruss P, Wynshaw-Boris A, Garrett L, Li M, Furth PA, Hennighausen L 1997. Cre-mediated gene deletion in the mammary gland.
Nucleic Acids Res 25 :4323-4330.
[PubMED
Abstract]
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