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Strain
Number: |
01XA8 |
Common
Strain Name: |
WAP-Cre |
Strain
Nomenclature: |
B6.Cg-Tg(Wap-Cre)11738Mam |
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Release
Category (Required for MTA form):
C,D
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Animal Health Report in PDF Format |
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Strain
Description: |
Cre is expressed in the secretory epithelium of the mammary gland in this strain. |
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Mutation
Information |
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Mutation
Type: |
Transgenic |
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Gene
Name: |
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Gene
Symbol: |
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Transgene
Name: |
Cre recombinase
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Transgene
Symbol: |
Cre
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Promoter
Name: |
Whey acidic protein (mouse) |
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Promoter
Symbol: |
Wap |
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Current
Genetic Background: |
B6.Cg |
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Approx.
Generation: |
25 |
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Organ
Site : |
Breast |
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Husbandry: |
Breeder pairs are supplied as a hemizygote (male or female) and a C57BL/6NCr mate. |
Genotyping Information: |
Protocol 2: Allele: Tg(Wap-Cre)11738Mam
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Donating
Investigator: |
Dr. Lothar Hennighausen |
Key
Reference: |
Wagner KU, Wall RJ, St-Onge L, Gruss P, Wynshaw-Boris A, Garrett L, Li M, Furth PA, Hennighausen L. 1997. Cre-mediated gene deletion in the mammary gland.
Nucleic Acids Res. 25:4323-30.
PMID: 9336464
[PubMED
Abstract]
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