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Treponema denticola Search Results

Record: 1 of 1 MiniMap

Gene ID:TDE0085DNA Molecule Name: 1 GenBank ID: 42525604Gene Name: rexA recB addA Definition: ATP-dependent nuclease subunit A (exonuclease V)Cellular Location: Cytoplasm [Evidence]Gene Start: 101105Gene Stop: 97689Gene Length: 3417Molecular Weight*: 130985pI*:Net Charge*:EC: Functional Class: Replication; Degradation of DNA Gene Ontology:Pathway: pathway tableSecondary Evidence: el Karoui,M., Ehrlich,D. and Gruss,A. Identification of the lactococcal exonuclease/recombinase and its modulation by the putative Chi sequence Proc. Natl. Acad. Sci. U.S.A. 95 (2), 626-631 (1998) PubMed: 9435243 Glickman BW. rorA mutation of Escherichia coli K-12 affects the recB subunit of exonuclease V. J Bacteriol. 1979 Jan;137(1):658-60. PMID: 368034Comment: There are no genes that correspond to the previously reported nucleotide sequence for the ATP-dependent nuclease subunit B (addB/rexB) in GenBank.View in HOMD Genome ViewerBlast Summary: PSI-Blast Search TDE0085 has significant similarity to the Treponema pallidum gene TP0898 (1e-152). TDE0085 has significant similarity to the Borrelia burgdorferi gene 15594978 (3e-32).Top Blast Hits: Updated monthly Click here to view the entire PsiBlast results. gi|42525604|ref|NP_970702.1| ATP-dependent DNA helicase, Uv... 2153 0.0 gi|15639883|ref|NP_219333.1| ATP-dependent nuclease, subuni... 540 e-151 gi|15615542|ref|NP_243846.1| ATP-dependent nuclease subunit... 202 1e-49 gi|91201897|emb|CAJ74957.1| similar to ATP-dependent DNA he... 201 4e-49 gi|154485117|ref|ZP_02027565.1| hypothetical protein EUBVEN... 191 3e-46 gi|116621025|ref|YP_823181.1| UvrD/REP helicase [Solibacter... 185 2e-44 gi|116493558|ref|YP_805293.1| ATP-dependent exoDNAse (exonu... 181 2e-43 gi|90962576|ref|YP_536492.1| ATP-dependent nuclease subunit... 181 2e-43 gi|30019293|ref|NP_830924.1| ATP-dependent nuclease subunit... 179 9e-43 gi|118444179|ref|YP_877319.1| ATP-dependent nuclease subuni... 178 2e-42COGS Summary: COGS Search BeTs to clades of COG1074 COG name: ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Functional Class:� L The phylogenetic pattern of COG1074 is ----------rlb-efghsnujxit- Number of proteins in this genome belonging to this COG isBlocks Summary: Blocks Search Significant hit ( 3e-48) to 7/7 blocks of the IPB000212 family, which is described as "UvrD/REP helicase". Interpro entry for IPR000212. IPB000212A 30-40 7.4e-05 IPB000212B 58-75 1.2e-06 IPB000212C 350-361 0.0045 IPB000212D 392-405 2e-08 IPB000212E 428-446 0.14 IPB000212F 742-760 4.7e-10 IPB000212G 817-829 0.0015ProDom Summary: Protein Domain Search Residues 650 to 1133 match (2e-41) PD:PD576281 which is described as ATP-DEPENDENT PROTEOME SUBUNIT A NUCLEASE COMPLETE Residues 293 to 505 match (3e-37) PD:PD040033 which is described as ATP-DEPENDENT PROTEOME SUBUNIT A NUCLEASE COMPLETE Residues 514 to 616 match (2e-23) PD:PD024188 which is described as PROTEOME COMPLETE V EXODEOXYRIBONUCLEASE HELICASE BETA CHAIN EXONUCLEASE NUCLEASE ATP-DEPENDENT Residues 19 to 75 match (1e-12) PD:PD000627 which is described as HELICASE COMPLETE PROTEOME DNA ATP-BINDING HYDROLASE ATP-DEPENDENT EXODEOXYRIBONUCLEASE II DNA-BINDING Residues 87 to 192 match (7e-12) PD:PD040033 which is described as ATP-DEPENDENT PROTEOME SUBUNIT A NUCLEASE COMPLETE Residues 742 to 837 match (4e-10) PD:PD326175 which is described as A ATP-DEPENDENT PROTEOME SUBUNIT NUCLEASE COMPLETE Residues 348 to 443 match (1e-07) PD:PD001658 which is described as HELICASE DNA PROTEOME COMPLETE ATP-DEPENDENT HYDROLASE II 3.6.1.- ATP-BINDING REPParalogs: Local Blast Search TDE0085 is paralogously related to TDE0903 (ATP-dependent DNA helicase) (2e-24) and TDE2335 (ATP-dependent DNA helicase II) (5e-17).Pfam Summary: Pfam Search Residues 12 to 677 (E-value = 2.6e-77) place TDE0085 in the UvrD-helicase family which is described as UvrD/REP helicase (PF00580)Top PDB Hits: No PDB hits found using the nr database and 5 rounds of Psi-BLAST (E-value < 0.01)Gene Protein Sequence: MNDYIKNIMDSLNENQKNAVSVEKNSVIAAGAGSGKTKVLAARYVYFVVE KGVSVEKIIALTFTEKAAAEMHKRIYNELKKIDHPNAKNAIEKFHLAKIS TIDSFCNRIARDACRNLGISPDFNIDNTESEKLAYRIGLDFFLKMRSDKT MQFFLGDNGIDDFVSGLFVKLLSNYVLISRPIDFKKSLEDQIKYHDDEER KTLAECFDVFEFIKENDPSKNFTEEAISEFSTLPHFPESIKDEAFIKLLP IVDKISKTAKGRGNDAVKEIKEKLKIIYEKLICIYNFDYSRDFLASFFDM LNELQKEYIYEKKQRGLLTFSDVSQLAVDVLINDIDLRNFYKKNADIIMI DEFQDNNSLQRDLLFLIAEKFERSEKFVPGPHELCPNKLFFVGDEKQSIY AFRGADVSVFRKLADDISDKERLAATRLLINYRTEPTLINLFNTIFSKVF YSEVNKPLEKNGFVPAYEAEYVPTETRAPVKGIEPKIEIMFFDKKRFNAL EDSSRFLSPVEAEAFYLAKRILELRNQGFKIRDGKSARACSWSDFAVLLR ASTKQSTYERVFRNFGIPYRSVQQRGLFNDAPINDIYAMLKIIAYPSDKK TYAQVLHSPFVNIDDDAFAVLLLNFTKAFDISLAEKLNEKNKDAYLRACD LFARLNKNILTMSCAESVTYLWYEEAYRYFLLSNEENHHYMDLYDYLFEL ACQADINGLTFSQFVDLLSSHIEDNERLDDMELPLDDQKDSVQFLTVHKS KGLEFPIVIVPDCGNRGIPEKKEGLVFYNEDMGPVLYSPKAPGLPAKAGN LIFESLRDEANAKLVAETKRLLYVAATRAESYLIISGVYNHLQNEDSKDS KKDVTKDNDCSSSDSRSLEEIKSMLKLSDKTISFFELLLPALPDKHEDII FTEILPTERKKLFNNLKTQKHEKVNFEKLFASSKVKEFNLAEKRITTATS LAHEVNKKSREGYLYSLTSEKDKLPDSFEDKDGQKEFTAAELGTLTHSLI EARLLNKEFIYPKGHSEVERKKIYAWADNFFNSDMYVLAKEAEQLKSEYG FLTDYEGQIVSGQIDLLFKKSGIVYVVDYKTDEIENPDSHLTQLKIYKKA ASDLAKTESENLKENTDKPIEVKTFIFYLKTGHCVELKTGene Nucleotide Sequence: Sequence Viewer ATGAATGATTATATAAAAAATATAATGGATAGTTTAAATGAAAATCAAAA AAATGCAGTAAGCGTTGAAAAAAATTCCGTAATTGCTGCGGGAGCCGGTT CCGGAAAAACGAAAGTGTTGGCTGCGCGCTATGTTTATTTTGTTGTTGAA AAGGGTGTCAGCGTAGAAAAAATAATAGCTCTAACCTTTACCGAAAAAGC CGCAGCCGAGATGCACAAAAGAATTTATAACGAGTTAAAAAAAATAGATC ATCCTAACGCAAAAAATGCTATCGAAAAATTTCATCTTGCAAAAATTTCG ACGATAGATTCTTTTTGCAATCGAATAGCAAGGGATGCATGTAGAAACTT AGGTATTTCTCCCGATTTTAACATTGATAATACCGAATCGGAAAAGTTGG CTTACCGCATAGGCTTGGATTTCTTTTTGAAAATGCGCTCGGATAAAACG ATGCAGTTTTTTTTAGGTGATAACGGCATAGATGATTTTGTGTCGGGCCT TTTTGTAAAATTATTAAGTAATTATGTTTTGATTTCAAGACCAATTGATT TTAAAAAAAGTTTGGAAGATCAAATAAAATATCATGATGACGAAGAAAGA AAAACTCTAGCGGAATGTTTTGATGTTTTTGAATTTATAAAAGAAAACGA TCCTTCTAAAAATTTTACGGAAGAAGCTATTAGCGAGTTTTCTACCCTTC CTCATTTTCCAGAATCGATAAAAGATGAAGCCTTTATTAAGCTGCTTCCT ATTGTAGATAAAATTTCTAAAACAGCAAAAGGTAGAGGAAATGATGCCGT AAAAGAAATAAAAGAAAAATTAAAAATCATATATGAAAAACTTATATGTA TTTATAATTTTGACTACTCACGAGATTTCTTAGCTTCTTTTTTTGATATG CTTAATGAGCTTCAAAAAGAATATATATATGAAAAAAAACAAAGAGGTCT TTTAACTTTTTCGGATGTGTCACAGCTTGCTGTGGATGTTTTGATAAATG ACATAGATTTACGAAACTTTTATAAAAAGAATGCAGACATTATTATGATA GATGAGTTTCAAGATAACAATAGTCTGCAAAGAGATTTGCTTTTTTTAAT TGCCGAAAAATTTGAACGCTCCGAAAAATTCGTGCCCGGTCCTCACGAAC TTTGTCCCAATAAACTTTTTTTTGTCGGAGATGAAAAGCAGTCGATTTAT GCTTTTAGAGGAGCTGATGTTTCCGTATTCCGAAAACTTGCTGACGATAT TTCGGATAAAGAAAGACTTGCCGCTACAAGGCTTTTGATAAATTACCGCA CGGAGCCTACTCTTATAAATTTATTTAATACAATATTCTCCAAAGTTTTT TATTCCGAGGTAAATAAGCCCTTGGAAAAAAACGGATTTGTTCCCGCCTA TGAAGCGGAATATGTGCCGACTGAAACGAGAGCTCCTGTAAAAGGGATTG AGCCTAAAATTGAAATAATGTTTTTTGATAAAAAAAGATTTAATGCTTTG GAAGATTCAAGCCGGTTTCTTAGTCCTGTAGAAGCTGAAGCTTTTTATCT TGCAAAAAGAATTTTAGAATTGCGTAATCAAGGTTTTAAAATTAGGGACG GTAAATCTGCAAGAGCTTGTTCATGGAGCGACTTTGCCGTCTTGCTCAGA GCTTCAACAAAGCAAAGTACATACGAAAGAGTTTTCCGCAATTTTGGTAT TCCTTATAGGAGTGTACAGCAAAGAGGTTTGTTTAATGATGCGCCTATAA ATGATATTTATGCTATGCTTAAAATTATAGCCTATCCTTCCGATAAAAAA ACTTATGCTCAAGTTTTACATTCGCCTTTTGTAAATATAGATGATGATGC CTTTGCAGTTTTACTTTTAAATTTTACAAAAGCTTTCGATATTTCTTTAG CGGAAAAATTAAATGAAAAAAATAAAGATGCCTATTTGCGGGCTTGCGAT TTATTTGCTCGCTTAAATAAAAATATTTTAACTATGAGCTGTGCCGAGTC GGTTACATATCTTTGGTATGAAGAAGCTTATAGATATTTTTTATTGAGCA ATGAAGAAAATCATCACTATATGGATTTATATGATTATCTTTTTGAGCTT GCATGTCAGGCTGATATCAACGGATTAACTTTTTCTCAATTTGTGGATTT GCTTTCATCTCATATTGAAGATAATGAAAGACTTGATGATATGGAGCTTC CCTTAGATGATCAAAAAGACTCCGTTCAATTTTTAACTGTGCATAAGAGC AAGGGTTTGGAATTCCCTATTGTTATAGTTCCCGACTGCGGAAATAGGGG TATCCCTGAAAAAAAAGAGGGGCTCGTTTTTTATAATGAAGATATGGGAC CTGTTTTGTATTCTCCTAAGGCTCCGGGCTTGCCTGCGAAAGCTGGCAAT CTGATTTTTGAATCATTACGTGATGAGGCTAATGCAAAGCTTGTTGCAGA AACAAAACGGCTTCTTTATGTTGCAGCTACAAGAGCTGAATCCTATTTAA TTATAAGCGGCGTATATAATCATTTACAAAATGAAGACTCTAAAGATTCT AAAAAAGATGTGACCAAAGATAATGATTGTTCATCTTCAGATTCAAGAAG TCTTGAAGAAATAAAAAGCATGCTTAAACTTTCGGACAAGACTATAAGCT TTTTTGAATTGCTTTTGCCTGCTCTTCCCGATAAACATGAAGATATTATT TTTACTGAGATTTTACCTACCGAAAGAAAGAAGCTGTTTAATAATTTAAA AACACAAAAGCATGAAAAAGTCAATTTTGAAAAACTTTTTGCTTCTTCTA AAGTAAAAGAATTTAATCTTGCAGAAAAAAGAATAACTACCGCTACAAGT CTTGCTCATGAGGTAAATAAAAAATCAAGAGAAGGTTATTTGTATTCTTT AACTTCTGAAAAAGATAAGCTGCCTGATTCTTTTGAAGATAAAGATGGAC AAAAAGAATTTACAGCGGCCGAGTTGGGAACTCTTACCCACTCCTTAATA GAAGCTCGTCTTTTAAATAAAGAATTTATTTATCCAAAAGGTCATTCCGA AGTTGAAAGAAAAAAGATTTATGCTTGGGCCGATAATTTCTTTAATTCGG ATATGTATGTTCTTGCAAAAGAAGCCGAACAATTAAAAAGCGAATACGGT TTTTTAACGGATTATGAAGGGCAAATTGTAAGCGGGCAGATAGACTTACT TTTTAAAAAAAGCGGAATAGTCTATGTTGTCGACTATAAAACCGATGAGA TAGAAAATCCGGATTCACACTTAACCCAGCTGAAGATTTATAAAAAAGCC GCCTCTGATCTTGCAAAAACCGAATCGGAAAATCTTAAAGAAAATACTGA TAAGCCAATCGAGGTTAAGACCTTTATCTTCTATCTAAAAACGGGACATT GTGTTGAGCTTAAAACA

Los Alamos National Laboratory • Est 1943