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Heart compromise in AIDS. Results from the first peruvian multicentric cohort.

Valenzuela GV, Guerra OE, Medina F, Samalvides F, Castillo R, Salazar R, Gotuzzo E; International Conference on AIDS.

Int Conf AIDS. 2002 Jul 7-12; 14: abstract no. ThPeB7377.

Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru

BACKGROUND: The heart is the worst organ studied in people with AIDS, probably because its affectation had a long clinical course. Perhaps, some of their pathologies like Pericardial Effusions (PE) and Dilated Cardiomyopathy (DCM) had been associated with a higher morbidity and mortality. METHODS: We carried out from August 2001 to January 2002, the first study in our country in two centers of reference, from social security and health ministry respectively, using echocardiographic measurements to evaluate ambulatory patients in AIDS stage. RESULTS: 114 persons were included. The mean age was 35.9 years (SD 8.5). 67.5% were male. The mean count of CD4 was 152.5 (cell/Ul) and 78.4% had counts below 200. 45.9% were receiving antiretroviral therapy. In functional study we found Diastolic Disfunction (DD) in 28.9%, restrictive pattern in 1.71% and systolic dysfunction in 1.71%. The morphologic study showed PE in 9.64%, Mitral Valve Prolapse (MVP) in 20% and DCM in 1.71%. Doppler study showed mitral insuficiency in 34.2%, tricuspideal insuficiency in 52.6%, pulmonary insuficiency in 48.2% and aortic insuficiency in 26.3% CONCLUSIONS: Our dates are the first reported in our country. We found a 28.9% with DD and their clinical evolution must be investigated. MVP was found in 20% and is recognized as a risk factor of endocarditis. On the other hand, insuficiency of heart valves are higher than the reported in epidemiological studies. We suggest the evaluation and follow up using echocardiography of people with HIV infection, specially of those in AIDS stage.

Publication Types:
  • Meeting Abstracts
Keywords:
  • Acquired Immunodeficiency Syndrome
  • Cardiomyopathy, Dilated
  • Echocardiography
  • Echocardiography, Doppler
  • Epidemiologic Studies
  • Heart Diseases
  • Heart Valve Prosthesis
  • Humans
  • Male
  • Mitral Valve Prolapse
  • Pericardial Effusion
  • Risk Factors
  • ultrasonography
Other ID:
  • GWAIDS0013869
UI: 102251367

From Meeting Abstracts




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