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There are a total of 34 record(s) matching your query.
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Prebiotic Polymer Synthesis and the Origin of Glycolytic Metabolism
Author(s): Weber, Arthur L.
Abstract: Our research resulted in several discoveries which contributed to understanding the origin and operation of life. (1) Most importantly, we discovered a new pathway of prebiotic amino acid synthesis in which formaldehyde and ...
NASA Center: Ames Research Center Publication Year: 1998
Added to NTRS: 2008-06-02
Document ID: 19990040549
The Sugar Model: Autocatalytic Activity of the Triose-Ammonia Reaction
Author(s): Weber, Arthur L.
Abstract: Reaction of triose sugars with ammonia under anaerobic conditions yielded autocatalytic products. The autocatalytic behavior of the products was examined by measuring the effect of the crude triose-ammonia reaction product ...
NASA Center: Ames Research Center Publication Year: 2006
Added to NTRS: 2006-11-22
Document ID: 20060051844
Chemical constraints governing the origin of metabolism: the thermodynamic landscape of carbon group transformations under mild aqueous conditions
Author(s): Weber, Arthur L.
Abstract: The thermodynamics of organic chemistry under mild aqueous conditions was examined in order to begin to understand its influence on the structure and operation of metabolism and its antecedents. Free energies (deltaG) were ...
NASA Center: Ames Research Center Publication Year: 2002
Added to NTRS: 2006-08-02
Document ID: 20040087958
Prebiotic Peptide Synthesis
Author(s): Weber, Arthur L.
Abstract: Chemical processes occurring on the primitive Earth about four billion years ago yielded molecules that had the ability to make copies of themselves or replicate. These rudimentary replicating molecules eventually developed ...
NASA Center: Ames Research Center Publication Year: 2000
Added to NTRS: 2005-11-24
Document ID: 20040077087
Prebiotic Synthesis of Activated Amino Acids
Author(s): Weber, Arthur L.
Abstract: About four billion years ago chemical processes occurring on the primitive Earth yielded molecules that had the ability to make copies of themselves (i.e., replicate). These rudimentary replicating molecules eventually ...
NASA Center: Ames Research Center Publication Year: 1998
Added to NTRS: 2005-11-24
Document ID: 20040075730
Prebiotic polymer synthesis and the origin of glycolytic metabolism
Author(s): Weber, Arthur L.
Abstract: In the past three years we have made significant progress in four research areas: (1) We developed a new model prebiotic polymer synthesis that yields polydisulfide polymers when dithiols are oxidized by iron(III) of ...
NASA Center: NASA (non Center Specific) Publication Year: 1994
Added to NTRS: 2005-08-25
Accession Number: 95N70194; Document ID: 19950002079; Report Number: NAS 1.26:196810, NASA-CR-196810
Model of early self-replication based on covalent complementarity for a copolymer of glycerate-3-phosphate and glycerol-3-phosphate
Author(s): Weber, Arthur L.
Abstract: Glyceraldehyde-3-phosphate acts as the substrate in a model of early self-replication of a phosphodiester copolymer of glycerate-3-phosphate and glycerol-3-phosphate. This model of self-replication is based on covalent ...
NASA Center: NASA (non Center Specific) Publication Year: 1989
Added to NTRS: 2005-08-25
Accession Number: 89N23693; Document ID: 19890014322; Report Number: NAS 1.26:182912, NASA-CR-182912
Redox Energy and Sulfur Chemistry in Prebiotic Polymer Synthesis and Replication
Author(s): Weber, Arthur L.
Abstract: In the past year we have made significant progress in three research areas: (1) Most importantly, we discovered a new pathway of prebiotic amino acid synthesis in which formaldehyde and glycolaldehyde (substrates of the ...
NASA Center: Ames Research Center Publication Year: 1997
Added to NTRS: 2005-08-25
Document ID: 19980007726; Report Number: NAS 1.26:205290, NASA-CR-205290
Prebiotic Peptide Synthesis
Author(s): Weber, Arthur L.
Abstract: About four billion years ago on the primitive Earth, chemical processes yielded molecules that had the ability to make copies of themselves (self-replicate). Over evolutionary time, these replicating molecules developed into ...
NASA Center: Ames Research Center Publication Year: 2002
Added to NTRS: 2005-08-25
Document ID: 20040171744
Redox energy and sulfur chemistry in prebiotic polymer synthesis and replication
Author(s): Weber, Arthur L.
Abstract: In the past three years we have made significant progress in for research areas: (1) we developed a new model of prebiotic polymer synthesis that yields polydisulfide polymers when dithiols are oxidized by iron (3) of ...
NASA Center: NASA (non Center Specific) Publication Year: 1995
Added to NTRS: 2005-08-25
Accession Number: 95N71563; Document ID: 19950003443; Report Number: NAS 1.26:199062, NASA-CR-199062
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