PUMA2 -- Evolutionary Analysis of Metabolism | |||
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EC-number: 3.5.99.6 ----- glucosamine-6-phosphate deaminase |
EC-NUMBER | 3.5.99.6 | |
ENZYME-NAME | glucosamine-6-phosphate deaminase | |
ENZYME-SYSNAME | Formerly EC 5.3.1.10. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol, which then hydrolyses to yield fructose 6-phosphate and ammonia. N-Acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme. | |
ENZYME-CLASS | Hydrolases Acting on carbon-nitrogen bonds, other than peptide bonds In other compounds | |
SYNONYMS | aminodeoxyglucosephosphate isomerase;; glucosamine phosphate deaminase;; glucosamine-6-phosphate deaminase;; glucosamine-6-phosphate isomerase;; >>more synonyms | |
REACTION | D-glucosamine 6-phosphate + H2O = D-fructose 6-phosphate + NH3 [RN:R00765] | |
PATHWAY | EMP-PATHWAYS: Glucosamine(,periplasm)--Fructose_6-phosphate,_NH(,3)_Catabolism_(plasma_membrane,_cytosol); >>more EMP pathways | |
KEGG-PATHWAYS: Aminosugars metabolism; >>more KEGG pathways | ||
GO_TERM | GO:0004342:glucosamine-6-phosphate deaminase activity | |
ENZYME-COMMENT | 2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing) | |
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To perform phylogenetic analysis:
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