National Cancer Institute National Cancer Institute
U.S. National Institutes of Health National Cancer Institute
Send to Printer
NCI Drug Dictionary

dianhydrogalactitol
A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in disruption of DNA function and cell cycle arrest. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)

Synonyms:dianhydrodulcitol
diepoxydulcitol
diepoxygalactitol
dulcitol diepoxide
galactitol
Abbreviation:DAG
Chemical structure names:
  • 1,2,5,6 dianhydrogalactitol
  • 1,2:5, 6-diepoxydulcitol
  • 1,2:5,6 dianhydrogalactitol
  • 1,2:5,6-dianhydrodulcitol
  • galactitol, 1,2:5,6-dianhydro- (8CI 9CI)

Previous:dextroamphetamine-amphetamine, dexverapamil, Dezone, DHA-paclitaxel, DHEA mustard
Next:Diastyl, diaziquone, diazooxonorleucine, diazoxide, dichloromethotrexate