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Sponsors and Collaborators: |
Henry Ford Health System M.D. Anderson Cancer Center |
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Information provided by: | Henry Ford Health System |
ClinicalTrials.gov Identifier: | NCT00367224 |
The purpose of this study is to determine if vitiligo patients develop tolerance to ultraviolet light therapy, a type of treatment available for vitiligo.
Condition | Intervention |
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Vitiligo |
Procedure: 6 to 9 ultraviolet B treatments Procedure: Skin biopsies |
Study Type: | Interventional |
Official Title: | Determining the Tolerance of Depigmented Skin to Targeted Phototherapy Using UVB in Patients With Vitiligo |
Enrollment: | 17 |
Study Start Date: | January 2006 |
Study Completion Date: | May 2008 |
Primary Completion Date: | May 2008 (Final data collection date for primary outcome measure) |
Patients with vitiligo received 6-9 ultraviolet B treatments, 2 to 3 times weekly. Minimal erythema dose (MED) testing was done at baseline and after all treatments; the percent change in MED was analysed as a measure of photoadaptation. The percent decrease in cyclobutane pyrimidine dimers (CPDs) over 24 hours after a single exposure of 1 MED was analysed on vitiliginous and normal skin.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
For inclusion, the subject must:
Exclusion Criteria:
Subjects will be excluded if any of the following apply:
United States, Michigan | |
Department of Dermatology/Henry Ford Hospital | |
Detroit, Michigan, United States, 48202 |
Principal Investigator: | Iltefat Hamzavi | Department of Dermatology, Henry Ford Health System |
Responsible Party: | Henry Ford Hospital, Department of Dermatology ( Iltefat Hamzavi, MD and Camile Hexsel, MD ) |
Study ID Numbers: | IRB3701 |
Study First Received: | August 18, 2006 |
Last Updated: | January 28, 2009 |
ClinicalTrials.gov Identifier: | NCT00367224 |
Health Authority: | United States: Institutional Review Board |
vitiligo tolerance ultraviolet B. |
Hypopigmentation Skin Diseases Pigmentation Disorders Hypomelanotic disorder Vitiligo |