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Title Presence of abscisic acid, a phytohormone, in the mammalian brain
Creator/Author Le Page-Degivry, M.T. ; Bidard, J.N. ; Rouvier, E. ; Bulard, C. ; Lazdunski, M.
Publication Date1986 Feb 01
OSTI IdentifierOSTI ID: 6413821
Other Number(s)CODEN: PNASA
Resource TypeJournal Article
Resource RelationProc. Natl. Acad. Sci. U.S.A. ; Vol/Issue: 83:4
Research OrgUniversite de Nice, France
Subject550601 -- Medicine-- Unsealed Radionuclides in Diagnostics; ABSCISIC ACID-- RADIOIMMUNOASSAY;BRAIN-- CHEMICAL ANALYSIS; GAS CHROMATOGRAPHY;HEART;IODINE 125;KIDNEYS;LIVER;LUNGS;MASS SPECTROSCOPY;PLANTS;RATS;SWINE
Related SubjectANIMALS;AUXINS;BETA DECAY RADIOISOTOPES;BODY;CARBOXYLIC ACIDS;CARDIOVASCULAR SYSTEM;CENTRAL NERVOUS SYSTEM;CHROMATOGRAPHY;DAYS LIVING RADIOISOTOPES;DIGESTIVE SYSTEM;DOMESTIC ANIMALS;ELECTRON CAPTURE RADIOISOTOPES;GLANDS;IMMUNOASSAY;IMMUNOLOGY;INTERMEDIATE MASS NUCLEI;IODINE ISOTOPES;ISOTOPE APPLICATIONS;ISOTOPES;MAMMALS;MONOCARBOXYLIC ACIDS;NERVOUS SYSTEM;NUCLEI;ODD-EVEN NUCLEI;ORGANIC ACIDS;ORGANIC COMPOUNDS;ORGANS;PLANT GROWTH REGULATORS;RADIOASSAY;RADIOIMMUNOLOGY;RADIOISOTOPES;RESPIRATORY SYSTEM;RODENTS;SEPARATION PROCESSES;SPECTROSCOPY;TRACER TECHNIQUES;VERTEBRATES
Description/Abstract This paper reports the presence of abscisic acid, one of the most important phytohormones, in the central nervous system of pigs and rats.^The identification of this hormone in brain was made after extensive purification by using a radioimmunoassay that is very specific for (+)-cis-abscisic acid.^The final product of purification from mammalian brain has the same properties as authentic abscisic acid: it crossreacts in the radioimmunoassay for the phytohormone and it has the same retention properties and the same gas chromatography/mass spectrometry characteristics.^Moreover, like (+)-cis-abscisic acid itself, the brain factor inhibits stomatal apertures of abaxial epidermis strips of Setcreasea purpurea Boom (Commelinaceae).^The presence of abscisic acid conjugates that are present in plants has also been identified in brain.
Country of PublicationUnited States
LanguageEnglish
FormatPages: 1155-1158
System Entry Date2001 May 13

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