The TAL abort mode was developed to improve the options available when a main engine fails after the last RTLS opportunity but before the first time that an AOA can be accomplished with only two main engines or when a major orbiter system failure, for example, a large cabin pressure leak or cooling system failure, occurs after the last RTLS opportunity, making it imperative to land as quickly as possible.

In a TAL abort, the vehicle continues on a ballistic trajectory across the Atlantic Ocean to land at a predetermined runway. Landing occurs approximately 45 minutes after launch. The landing site is selected near the nominal ascent ground track of the orbiter in order to make the most efficient use of space shuttle main engine propellant. The landing site also must have the necessary runway length, weather conditions and U.S. State Department approval. Currently, the three landing sites that have been identified for a due east launch are Moron, Spain; Banjul, The Gambia; and Ben Guerir, Morocco.

To select the TAL abort mode, the crew must place the abort rotary switch in the TAL/AOA position and depress the abort push button before main engine cutoff. (Depressing it after main engine cutoff selects the AOA abort mode.) The TAL abort mode begins sending commands to steer the vehicle toward the plane of the landing site. It also rolls the vehicle heads up before main engine cutoff and sends commands to begin an orbital maneuvering system propellant dump (by burning the propellants through the orbital maneuvering system engines and the reaction control system engines). This dump is necessary to increase vehicle performance (by decreasing weight), to place the center of gravity in the proper place for vehicle control, and to decrease the vehicle's landing weight.

TAL is handled like a nominal entry.