R = Retrieve links to Related sequences (neighbors).
Use the 
icon (if present) to retrieve links to the Sequence Retrieval System (SRS).
Use the 
icon (if present) to retrieve links to the Ligand Enzyme and Chemical Compound Database .
Use the 
icon (if present) to retrieve links to the Protein Data Bank database.
>gi|6573737|gb|AAF17657.1|AC009398_6 (AC009398) F20B24.11 [Arabidopsis
thaliana]
Length = 423
Frame 3 hits (HSPs): ___________________
__________________________________________________
Database sequence: | | | | 423
0 150 300
Plus Strand HSPs:
Score = 567 (199.6 bits), Expect = 6.2e-54, P = 6.2e-54
Identities = 112/155 (72%), Positives = 126/155 (81%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPD 239
MARKKIREYDSKRL+KEHFKRLSGKELPI+S QI +TD EL EKEPWLSS KLVVKPD
Sbjct: 1 MARKKIREYDSKRLVKEHFKRLSGKELPIRSVQINETTDLNELVEKEPWLSSEKLVVKPD 60
Query: 240 MLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTFIVEPFIPHNEEFYLN 419
MLFGKRGKSGLVAL LDFA V +FVKERLGKEVEMSGCKGPITTFIVEPF+PHNEE+YLN
Sbjct: 61 MLFGKRGKSGLVALKLDFADVATFVKERLGKEVEMSGCKGPITTFIVEPFVPHNEEYYLN 120
Query: 420 IAPRDLGTV*AFQNXEELKXKTTGDKVRLLW-STG 521
+ LG +F ++ + DKV+ ++ TG
Sbjct: 121 VVSDRLGCSISFSECGGIEIEENWDKVKTIFLPTG 155
>gi|2462746|gb|AAB71965.1| (AC002292) Similar to ATP-citrate-lyase [Arabidopsis
thaliana]
Length = 423
Frame 3 hits (HSPs): __________________
Frame 2 hits (HSPs): ______
__________________________________________________
Database sequence: | | | | 423
0 150 300
Plus Strand HSPs:
Score = 565 (198.9 bits), Expect = 1.0e-53, P = 1.0e-53
Identities = 111/150 (74%), Positives = 122/150 (81%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPD 239
MARKKIREYDSKRL+KEHFKRLSG+ELPI+S QI TD EL E+EPWLSS KLVVKPD
Sbjct: 1 MARKKIREYDSKRLVKEHFKRLSGQELPIRSVQINQETDLNELVEREPWLSSEKLVVKPD 60
Query: 240 MLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTFIVEPFIPHNEEFYLN 419
MLFGKRGKSGLVALNLDFA V +FVKERLGKEVEMSGCKGPITTFIVEPF+PHNEEFYLN
Sbjct: 61 MLFGKRGKSGLVALNLDFADVATFVKERLGKEVEMSGCKGPITTFIVEPFVPHNEEFYLN 120
Query: 420 IAPRDLGTV*AFQNXEELKXKTTGDKVRLL 509
I LG +F + + DKV+ +
Sbjct: 121 IVSDRLGCSISFSECGGIDIEENWDKVKTI 150
Score = 87 (30.6 bits), Expect = 4.3, P = 0.99
Identities = 23/45 (51%), Positives = 28/45 (62%), Frame = +2
Query: 425 SERLGNSISFSKXGGIEXEDNWG*GKTALVHWNAX-T*XSC-PLV 553
S+RLG SISFS+ GGI+ E+NW KT + A T C PLV
Sbjct: 123 SDRLGCSISFSECGGIDIEENWDKVKTITIPTGASLTFEICAPLV 167
>gi|3482918|gb|AAC33203.1|AAC33203 (AC003970) Similar to ATP-citrate-lyase
[Arabidopsis thaliana]
Length = 424
Frame 3 hits (HSPs): __________________
__________________________________________________
Database sequence: | | | | 424
0 150 300
Plus Strand HSPs:
Score = 505 (177.8 bits), Expect = 2.3e-47, P = 2.3e-47
Identities = 99/151 (65%), Positives = 118/151 (78%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPD 239
MARKKIREYDSKRLLKEH KRL+ +L I+SAQ+T STDFTEL +E WLSS+KLVVKPD
Sbjct: 1 MARKKIREYDSKRLLKEHLKRLANIDLQIRSAQVTESTDFTELTNQESWLSSTKLVVKPD 60
Query: 240 MLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTFIVEPFIPHNEEFYLN 419
MLFGKRGKSGLVAL LD A+V FVK RLG EVEM GCK PITTFIVEPF+PH++E+YL+
Sbjct: 61 MLFGKRGKSGLVALKLDLAEVADFVKARLGTEVEMEGCKAPITTFIVEPFVPHDQEYYLS 120
Query: 420 IAPRDLGTV*AFQNXEELKXKTTGDKVRLLW 512
I LG +F ++ + DKV+ ++
Sbjct: 121 IVSDRLGCTISFSECGGIEIEENWDKVKTIF 151
>gi|12323802|gb|AAG51870.1|AC079675_5 (AC079675) ATP citrate-lyase, putative,
3' partial; 19757-20168 [Arabidopsis thaliana]
Length = 92
Frame 3 hits (HSPs): __________________________________________________
__________________________________________________
Database sequence: | | | | | | 92
0 20 40 60 80
Plus Strand HSPs:
Score = 392 (138.0 bits), Expect = 2.2e-35, P = 2.2e-35
Identities = 77/92 (83%), Positives = 82/92 (89%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPD 239
MARKKIREYDSKRL+KEHFKRLSG+ELPI+S QI TD EL E+EPWLSS KLVVKPD
Sbjct: 1 MARKKIREYDSKRLVKEHFKRLSGQELPIRSVQINQETDLNELVEREPWLSSEKLVVKPD 60
Query: 240 MLFGKRGKSGLVALNLDFAQVVSFVKERLGKE 335
MLFGKRGKSGLVALNLDFA V +FVKERLGKE
Sbjct: 61 MLFGKRGKSGLVALNLDFADVATFVKERLGKE 92
>gi|7490235|pir||T38156 citrate lyase - fission yeast (Schizosaccharomyces
pombe) >gi|2414609|emb|CAB16586.1| (Z99295) putative ATP-citrate
(pro-S-) lyase (EC 4.1.3.8) [Schizosaccharomyces pombe]
Length = 492
Frame 3 hits (HSPs): ________________
__________________________________________________
Database sequence: | | | | | 492
0 150 300 450
Plus Strand HSPs:
Score = 211 (74.3 bits), Expect = 1.2e-18, Sum P(2) = 1.2e-18
Identities = 37/84 (44%), Positives = 58/84 (69%), Frame = +3
Query: 177 FTELQEKEPWLSSSKLVVKPDMLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCK 356
F +++++ PW+ +KLV KPD L +RGKSGL+ LN + + +++ER GK ++
Sbjct: 68 FAKVEQEHPWVKETKLVAKPDQLIKRRGKSGLLKLNATWDEAKEWIRERAGKNQKVQHAV 127
Query: 357 GPITTFIVEPFIPH--NEEFYLNI 422
G +TTF+VEPF+PH N E+Y+NI
Sbjct: 128 GYLTTFLVEPFVPHPPNTEYYINI 151
Score = 52 (18.3 bits), Expect = 1.2e-18, Sum P(2) = 1.2e-18
Identities = 17/51 (33%), Positives = 23/51 (45%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSG--KELPIKSAQITASTDFTELQEKEPWL 209
M+ K IREYD K +L R KE K+ T + ++Q P L
Sbjct: 1 MSAKSIREYDGKAVLAYWLNRSPSISKE-EYKTVSATPAVQLAQIQFPLPTL 51
>gi|8392839 ref|NP_058683.1| ATP citrate lyase [Rattus norvegicus]
>gi|113116|sp|P16638|ACLY_RAT ATP-CITRATE (PRO-S-)-LYASE (CITRATE
CLEAVAGE ENZYME) >gi|111396|pir||A35007 ATP citrate (pro-S)-lyase
(EC 4.1.3.8) - rat >gi|203490|gb|AAA74463.1| (J05210) ATP
citrate-lyase [Rattus norvegicus]
Length = 1100
Frame 3 hits (HSPs): ______
__________________________________________________
Database sequence: | | | | | | | | | 1100
0 150 300 450 600 750 900 1050
Plus Strand HSPs:
Score = 245 (86.2 bits), Expect = 1.9e-18, P = 1.9e-18
Identities = 55/128 (42%), Positives = 75/128 (58%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPD 239
M+ K I E K LL ++ S + K A++T TD+ L + PWL S LVVKPD
Sbjct: 1 MSAKAISEQTGKELLYKYICTTSAIQNRFKYARVTPDTDWAHLLQDHPWLLSQSLVVKPD 60
Query: 240 MLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTFIVEPFIPHN--EEFY 413
L +RGK GLV +NL V S++K RLG E + KG + F++EPF+PH+ EEFY
Sbjct: 61 QLIKRRGKLGLVGVNLSLDGVKSWLKPRLGHEATVGKAKGFLKNFLIEPFVPHSQAEEFY 120
Query: 414 LNI-APRD 434
+ I A R+
Sbjct: 121 VCIYATRE 128
>gi|603074|gb|AAB60340.1| (U18197) ATP:citrate lyase [Homo sapiens]
Length = 1101
Frame 3 hits (HSPs): ______
__________________________________________________
Database sequence: | | | | | | | | | 1101
0 150 300 450 600 750 900 1050
Plus Strand HSPs:
Score = 237 (83.4 bits), Expect = 1.3e-17, P = 1.3e-17
Identities = 54/128 (42%), Positives = 74/128 (57%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPD 239
M+ K I E K LL + S + K A++T TD+ L + PWL S LVVKPD
Sbjct: 1 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD 60
Query: 240 MLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTFIVEPFIPHN--EEFY 413
L +RGK GLV +NL V S++K RLG+E + G + F++EPF+PH+ EEFY
Sbjct: 61 QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY 120
Query: 414 LNI-APRD 434
+ I A R+
Sbjct: 121 VCIYATRE 128
>gi|4501865 ref|NP_001087.1| ATP citrate lyase [Homo sapiens]
>gi|1703083|sp|P53396|ACLY_HUMAN ATP-CITRATE (PRO-S-)-LYASE
(CITRATE CLEAVAGE ENZYME) >gi|105392|pir||S21173 ATP citrate
(pro-S)-lyase - human >gi|28935|emb|CAA45614.1| (X64330)
ATP-citrate (pro-S-)-lyase [Homo sapiens]
Length = 1105
Frame 3 hits (HSPs): ______
__________________________________________________
Database sequence: | | | | | | | | | 1105
0 150 300 450 600 750 900 1050
Plus Strand HSPs:
Score = 228 (80.3 bits), Expect = 1.2e-16, P = 1.2e-16
Identities = 53/128 (41%), Positives = 73/128 (57%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPD 239
M+ K I E K LL + S + K A++T TD+ L + PWL S LVVKPD
Sbjct: 1 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD 60
Query: 240 MLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTFIVEPFIPHN--EEFY 413
L +RGK GLV ++L V S++K RLG+E + G + F++EPF PH+ EEFY
Sbjct: 61 QLIKRRGKLGLVGVDLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFAPHSQAEEFY 120
Query: 414 LNI-APRD 434
+ I A R+
Sbjct: 121 VCIYATRE 128
>gi|9229902|dbj|BAB00624.1| (AB036847) ATP citrate-lyase [Ciona intestinalis]
Length = 1101
Frame 3 hits (HSPs): ______
__________________________________________________
Database sequence: | | | | | | | | | 1101
0 150 300 450 600 750 900 1050
Plus Strand HSPs:
Score = 218 (76.7 bits), Expect = 1.4e-15, P = 1.4e-15
Identities = 49/132 (37%), Positives = 76/132 (57%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPD 239
M+ K I E +K +L ++ ++ A + ++ EL K PWL + KL+VKPD
Sbjct: 1 MSAKAINEITAKTILCKNIGDDINLSNRLRFASVDRCINWDELAVKHPWLLTEKLIVKPD 60
Query: 240 MLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTFIVEPFIPHN--EEFY 413
L +RGK GL+ +N D+A V +V ER+ KE+ + KG + FI+EPF+ H EEFY
Sbjct: 61 QLIKRRGKLGLIKINTDYAGVQQWVGERMLKEISIGETKGILKHFIIEPFVAHKQEEEFY 120
Query: 414 LNI-APRDLGTV 446
+ I + R+ T+
Sbjct: 121 ICIHSSREEDTI 132
>gi|7303012|gb|AAF58082.1| (AE003808) ATPCL gene product [Drosophila
melanogaster]
Length = 1086
Frame 3 hits (HSPs): ______
__________________________________________________
Database sequence: | | | | | | | | | 1086
0 150 300 450 600 750 900 1050
Plus Strand HSPs:
Score = 214 (75.3 bits), Expect = 3.8e-15, P = 3.8e-15
Identities = 43/123 (34%), Positives = 68/123 (55%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPD 239
M+ K I E K +L H + + + ++TD+++L PWL ++ LV KPD
Sbjct: 1 MSAKAITEASGKDILNRHLNTHGAGAATCRFSTVNSTTDWSKLAVDHPWLLTTPLVCKPD 60
Query: 240 MLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTFIVEPFIPHN--EEFY 413
L +RGK GL+ + +F QV ++ ERL K+ ++ G + FI+EPF+PH EE Y
Sbjct: 61 QLIKRRGKLGLIGVKKNFEQVKQWIGERLNKDQKIGNAVGKLRNFIIEPFVPHTDAEEMY 120
Query: 414 LNI 422
+ I
Sbjct: 121 VCI 123
>gi|7160184|emb|CAB76164.1| (AJ243817) ATP citrate lyase, subunit 2 [Sordaria
macrospora]
Length = 481
Frame 3 hits (HSPs): _________
__________________________________________________
Database sequence: | | | | | 481
0 150 300 450
Plus Strand HSPs:
Score = 167 (58.8 bits), Expect = 1.1e-10, P = 1.1e-10
Identities = 32/77 (41%), Positives = 50/77 (64%), Frame = +3
Query: 201 PWL--SSSKLVVKPDMLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTF 374
PWL ++ V KPD L +RGKSGL+ALN + + +++ ER GK ++ +G + F
Sbjct: 65 PWLLQDGARFVAKPDQLIKRRGKSGLLALNKTWPEAKAWIAERAGKAQKVEHTEGVLRQF 124
Query: 375 IVEPFIPHNEE--FYLN 419
+VEPF+PH +E +Y+N
Sbjct: 125 LVEPFVPHPQETEYYIN 141
>gi|7494888|pir||T18713 hypothetical protein B0365.1 - Caenorhabditis elegans
>gi|3873757|emb|CAB02690.1| (Z81028) Similarity to Human ATP
citrate lyase (TR:G603074), contains similarity to Pfam domain:
PF00549 (CoA-ligases), Score=254.2, E-value=5.6e-73, N=1~cDNA EST
yk1f3.3 comes from this gene~cDNA EST yk9g5.5 comes from this
gene~cDNA EST yk1f3.5 comes>
Length = 1099
Frame 3 hits (HSPs): ______
__________________________________________________
Database sequence: | | | | | | | | | 1099
0 150 300 450 600 750 900 1050
Plus Strand HSPs:
Score = 152 (53.5 bits), Expect = 2.3e-07, P = 2.3e-07
Identities = 39/122 (31%), Positives = 65/122 (53%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSS-SKLVVKP 236
M+ K + E K +L ++F+ P + + A F+++ K WL+ +K V+KP
Sbjct: 1 MSAKAVSELSGKEVLYKYFESTGIVSAP-HAFHVKAGDKFSDVAAKYEWLAQDNKGVIKP 59
Query: 237 DMLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTFIVEPFIPH--NEEF 410
D L +RGK GLV + ++ ++ + V++ +G + TFIVEPF H NEE
Sbjct: 60 DQLIKRRGKLGLVKIGSP-KELEAWFGKTANSYVKVGQTEGRLHTFIVEPFCAHTENEEM 118
Query: 411 YLNI 422
Y+ I
Sbjct: 119 YIAI 122
>gi|1703082|sp|P53585|ACLY_CAEEL PROBABLE ATP-CITRATE (PRO-S-)-LYASE (CITRATE
CLEAVAGE ENZYME) >gi|7498057|pir||T29496 hypothetical protein
D1005.1 - Caenorhabditis elegans >gi|1326262|gb|AAB00585.1|
(U58727) coded for by C. elegans cDNA yk133b7.5; coded for by C.
elegans cDNA yk133b7.3; coded for by C. elegans cDNA CEESE58F;
strong similarity to ATP citrate lyase and the alpha chain of
succinyl-coa synthases [Caenorhabditis elegans]
Length = 1106
Frame 3 hits (HSPs): ______
Frame 2 hits (HSPs): __
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | | | | | 1106
0 150 300 450 600 750 900 1050
__________________
Annotated Domains:
DOMO DM07845: 1..513
DOMO DM01167: SUCCINATE--COALIGASE(ADP-FORMIN 515..801
DOMO DM07844: 803..1105
Entrez active site: PHOSPHORYLATED IN THE COURS 760
PFAM ligase-CoA: CoA-ligases 642..793
PRODOM PD010086: ACLY(3) 1..430
PRODOM PD191737: ACLY(1) P90731(1) 432..477
PRODOM PD014373: ACLY(3) P90731(1) Q13037(1) 492..638
PRODOM PD002034: SUCD(8) SUCA(5) ACLY(3) 640..760
PRODOM PD013870: ACLY(3) P90731(1) Q13037(1) 762..873
PRODOM PD000990: CISY(35) CISZ(7) ACLY(3) 875..1078
PRODOM PD039315: ACLY(1) P90731(1) 1080..1102
__________________
Plus Strand HSPs:
Score = 150 (52.8 bits), Expect = 3.6e-07, Sum P(2) = 3.6e-07
Identities = 43/122 (35%), Positives = 64/122 (52%), Frame = +3
Query: 60 MARKKIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLS-SSKLVVKP 236
M+ K + E K +L ++F+ SG + + A +F E+ K WL+ +K V+KP
Sbjct: 1 MSAKAVSELSGKEVLYKYFEP-SGLLSAPHAFHVKAGENFDEIANKYEWLARDNKGVIKP 59
Query: 237 DMLFGKRGKSGLVALNLDFAQVVSFVKERLGKE-VEMSGCKGPITTFIVEPFIPHNE--E 407
D L +RGK GLV + Q + E+ G V + +G + TFIVEPF H E E
Sbjct: 60 DQLIKRRGKLGLVKIGTP--QELKAWFEKTGDSYVRVGQTEGRLHTFIVEPFCAHTEKDE 117
Query: 408 FYLNI 422
Y+ I
Sbjct: 118 MYIAI 122
Score = 38 (13.4 bits), Expect = 3.6e-07, Sum P(2) = 3.6e-07
Identities = 8/20 (40%), Positives = 12/20 (60%), Frame = +2
Query: 425 SERLGNSISFSKXGGIEXED 484
SER + I F + GG++ D
Sbjct: 124 SERFRDVIMFYEQGGVDIGD 143
>gi|12407235|dbj|BAB21375.1| (AB054669) ATP-citrate lyase beta-subunit
[Chlorobium limicola]
Length = 398
Frame 3 hits (HSPs): ____________
Frame 2 hits (HSPs): ___
__________________________________________________
Database sequence: | | | | 398
0 150 300
Plus Strand HSPs:
Score = 124 (43.7 bits), Expect = 1.4e-06, Sum P(2) = 1.4e-06
Identities = 32/95 (33%), Positives = 47/95 (49%), Frame = +3
Query: 138 LPIKSAQITASTD-FTELQEKEPWLSSSKLVVKPDMLFGKRGKSGLVALNLDFAQVVSFV 314
+P+ + + D +L E WL SKLVVK G R K GLV + L+ Q +
Sbjct: 18 IPVPNYVVIMDPDRLAQLGEANKWLRESKLVVKAHEAIGGRFKLGLVKIGLNLEQAIEAA 77
Query: 315 KERLGKEVEMSGCKGPITTFIVEPFIPHNEEFYLNI 422
KE LG +V + I I+ + H+ EFY++I
Sbjct: 78 KEMLGAKVGTA----EIGQVIIAEMLEHDAEFYVSI 109
Score = 56 (19.7 bits), Expect = 1.4e-06, Sum P(2) = 1.4e-06
Identities = 9/18 (50%), Positives = 12/18 (66%), Frame = +2
Query: 437 GNSISFSKXGGIEXEDNW 490
G + SK GG++ EDNW
Sbjct: 115 GAELLISKHGGVDIEDNW 132
>gi|3183562|sp|P80886|SUCC_BACSU SUCCINYL-COA SYNTHETASE BETA CHAIN (SCS-ALPHA)
(VEGETATIVE PROTEIN 63) (VEG63) >gi|7437894|pir||E69719
succinate--CoA ligase (ADP-forming) (EC 6.2.1.5) beta chain -
Bacillus subtilis >gi|2462967|emb|CAA04419.1| (AJ000975) putative
succinyl-coA synthetase beta chain [Bacillus subtilis]
>gi|2633981|emb|CAB13482.1| (Z99112) succinyl-CoA synthetase (beta
subunit) [Bacillus subtilis]
Length = 385
Frame 3 hits (HSPs): _______________
Annotated Domains: _________________________________________________
__________________________________________________
Database sequence: | | | | 385
0 150 300
__________________
Annotated Domains:
BLOCKS BL01216A: ATP-citrate lyase / succinyl-C 45..59
BLOCKS BL01216B: ATP-citrate lyase / succinyl-C 122..134
BLOCKS BL01216C: ATP-citrate lyase / succinyl-C 186..198
BLOCKS BL01216D: ATP-citrate lyase / succinyl-C 255..284
PFAM ligase-CoA: CoA-ligases 246..383
PRODOM PD000180: PUR2(17) CARB(16) PYR1(14) 9..127
PRODOM PD111317: SUCC(7) SUCB(4) 134..202
PRODOM PD003397: SUCC(8) SUCB(4) 204..383
PROSITE ATP_GTP_A: ATP/GTP-binding site motif A 73..80
PROSITE SUCCINYL_COA_LIG_3: ATP-citrate lyase / 257..281
__________________
Plus Strand HSPs:
Score = 97 (34.1 bits), Expect = 0.27, P = 0.24
Identities = 35/116 (30%), Positives = 55/116 (47%), Frame = +3
Query: 75 IREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPDMLFGK 254
I EY K +L+++ G +P TA E E LSSS VVK + G
Sbjct: 3 IHEYQGKEVLRKY-----GVSVPEGKVAFTAE----EAVESAKSLSSSVYVVKAQIHAGG 53
Query: 255 RGKSGLVALNLDFAQVVSFVKERLGKEV--EMSGCKGP-ITTFIVEPFIPHNEEFYLNI 422
RGK+G V + +V ++ +E LGK + +G G I ++E +E+Y+ +
Sbjct: 54 RGKAGGVKIAKSLDEVKAYAEELLGKTLVTHQTGPDGQVIKRLLIEEGCDIKKEYYIGL 112
>gi|12313152|emb|CAC24280.1| (AL512977) Succinyl-CoA synthetase, beta subunit
[Sulfolobus solfataricus]
Length = 337
Frame 3 hits (HSPs): ___________
__________________________________________________
Database sequence: | | | | 337
0 150 300
Plus Strand HSPs:
Score = 94 (33.1 bits), Expect = 0.48, P = 0.38
Identities = 27/75 (36%), Positives = 37/75 (49%), Frame = +3
Query: 198 EPWLSSSKLVVKPDMLFGKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTFI 377
EP K VVK +L G RGK GLV + D + +K +LG E F+
Sbjct: 27 EPIRWQGKAVVKSQLLEGARGKRGLVRVTEDIYNTILELK-KLGVE-----------KFL 74
Query: 378 VEPFIPHNEEFYLNI 422
VE F+PH +E Y ++
Sbjct: 75 VEEFVPHEKEIYASV 89
>gi|10175090|dbj|BAB06189.1| (AP001515) succinyl-CoA synthetase (beta subunit)
[Bacillus halodurans]
Length = 386
Frame 3 hits (HSPs): _______________
__________________________________________________
Database sequence: | | | | 386
0 150 300
Plus Strand HSPs:
Score = 94 (33.1 bits), Expect = 0.60, P = 0.45
Identities = 37/116 (31%), Positives = 60/116 (51%), Frame = +3
Query: 75 IREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPDMLFGK 254
I EY K LL+++ G +P + ++ S D E E L S+ VVK + G
Sbjct: 3 IHEYQGKELLRQY-----GVAVP--NGKVAFSVD--EAVEAAKELGSNVCVVKAQIHAGG 53
Query: 255 RGKSG--LVALNLDFAQVVSFVKERLGKEV--EMSGCKGP-ITTFIVEPFIPHNEEFYLN 419
RGK+G VA NLD +V ++ E LGK + +G +G + ++E +E+Y+
Sbjct: 54 RGKAGGVKVAKNLD--EVRTYADEILGKTLVTHQTGPEGKEVKRLLIEEGCDIQKEYYVG 111
Query: 420 I 422
+
Sbjct: 112 L 112
>gi|6647847|sp|O67546|SUCC_AQUAE SUCCINYL-COA SYNTHETASE BETA CHAIN (SCS-BETA)
>gi|7437895|pir||H70439 succinate--CoA ligase (ADP-forming) (EC
6.2.1.5) beta chain - Aquifex aeolicus >gi|2983961|gb|AAC07508.1|
(AE000748) succinyl-CoA ligase beta subunit [Aquifex aeolicus]
Length = 385
Frame 3 hits (HSPs): _______________
__________________________________________________
Database sequence: | | | | 385
0 150 300
Plus Strand HSPs:
Score = 92 (32.4 bits), Expect = 1.0, P = 0.64
Identities = 32/109 (29%), Positives = 52/109 (47%), Frame = +3
Query: 102 LKEH-FKRLSGKE-LPIKSAQITASTDFTELQEKEPWLSSSKLVVKPDMLFGKRGKSGLV 275
L EH K + K +P+ ++ S E +E L LVVK + G RGK+G V
Sbjct: 3 LHEHQAKEIFAKYGIPVPEGKVAFS--LKEAKEVAEELGEFPLVVKAQIHCGGRGKAGGV 60
Query: 276 ALNLDFAQVVSFVKERLGKEVEMSGCKG--PITTFIVEPFIPHNEEFYLNI 422
+ D ++ V+ LGK ++ C P+ ++E ++E+YL I
Sbjct: 61 KIVKDMDELEKAVESLLGKVLKTFQCPDGKPVNRVLIEKATNIDKEYYLAI 111
>gi|1174473|sp|P45101|SUCC_HAEIN SUCCINYL-COA SYNTHETASE BETA CHAIN (SCS-BETA)
>gi|1075329|pir||C64189 succinate--CoA ligase (ADP-forming) (EC
6.2.1.5) beta chain - Haemophilus influenzae (strain Rd KW20)
>gi|1574125|gb|AAC22850.1| (U32799) succinyl-CoA synthetase, beta
subunit (sucC) [Haemophilus influenzae Rd]
Length = 389
Frame 3 hits (HSPs): _______________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | 389
0 150 300
__________________
Annotated Domains:
BLOCKS BL01216A: ATP-citrate lyase / succinyl-C 45..59
BLOCKS BL01216B: ATP-citrate lyase / succinyl-C 122..134
BLOCKS BL01216C: ATP-citrate lyase / succinyl-C 179..191
BLOCKS BL01216D: ATP-citrate lyase / succinyl-C 255..284
DOMO DM01140: 1..388
PFAM ligase-CoA: CoA-ligases 246..388
PRODOM PD186273: SUCB(4) 1..132
PRODOM PD111317: SUCC(7) SUCB(4) 134..202
PRODOM PD003397: SUCC(8) SUCB(4) 204..384
PROSITE SUCCINYL_COA_LIG_3: ATP-citrate lyase / 257..281
__________________
Plus Strand HSPs:
Score = 91 (32.0 bits), Expect = 1.3, P = 0.73
Identities = 33/115 (28%), Positives = 56/115 (48%), Frame = +3
Query: 75 IREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQEKEPWLSSSKLVVKPDMLFGK 254
+ EY +K+L EH+ G LP+K+ + S + +L + LS K K + G
Sbjct: 3 LHEYQAKQLF-EHY----G--LPVKNGAVCQSVEDVDLVLAQ--LSGGKWAAKCQVHAGG 53
Query: 255 RGKSGLVALNLDFAQVVSFVKERLGKEV---EMSGCKGPITTFIVEPFIPHNEEFYLN 419
RGK+G V L D + +F ++ LG+ + + P+ E ++EFYL+
Sbjct: 54 RGKAGGVKLVQDVEEARAFAEKWLGQRLVTFQTDKLGQPVNQIYFEETCDIDKEFYLS 111
>gi|2500927|sp|Q57663|SUCC_METJA SUCCINYL-COA SYNTHETASE BETA CHAIN (SCS-BETA)
>gi|2129294|pir||C64326 succinyl-CoA synthetase, beta subunit -
Methanococcus jannaschii >gi|1590950|gb|AAB98195.1| (U67477)
succinyl-CoA synthetase, beta subunit [Methanococcus jannaschii]
Length = 364
Frame 3 hits (HSPs): ______________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | 364
0 150 300
__________________
Annotated Domains:
BLOCKS BL01216A: ATP-citrate lyase / succinyl-C 42..56
BLOCKS BL01216B: ATP-citrate lyase / succinyl-C 112..124
BLOCKS BL01216C: ATP-citrate lyase / succinyl-C 169..181
BLOCKS BL01216D: ATP-citrate lyase / succinyl-C 237..266
PFAM ligase-CoA: CoA-ligases 228..348
PRODOM PD000180: PUR2(17) CARB(16) PYR1(14) 6..106
PRODOM PD111317: SUCC(7) SUCB(4) 124..192
PRODOM PD003397: SUCC(8) SUCB(4) 194..361
PROSITE SUCCINYL_COA_LIG_3: ATP-citrate lyase / 239..263
__________________
Plus Strand HSPs:
Score = 87 (30.6 bits), Expect = 3.5, P = 0.97
Identities = 31/117 (26%), Positives = 60/117 (51%), Frame = +3
Query: 72 KIREYDSKRLLKEHFKRLSGKELPIKSAQITASTDFTELQ-EKEPWLSSSKLVVKPDMLF 248
K+ EY++K + K++ G +P +S ++ D + +KE +V+K +L
Sbjct: 2 KLHEYEAKNIFKKY-----GIPVP-ESFLVSKEDDLNSINVDKE-------VVLKAQVLV 48
Query: 249 GKRGKSGLVALNLDFAQVVSFVKERLGKEVEMSGCKGPITTFIVEPFIPHNEEFYLNI 422
G RGK+G + + + + +E KEV+ G K + +VE +P +E+Y++I
Sbjct: 49 GGRGKAGGILFASNKEEFIKKAEELFNKEVK--GEK--VEKILVEEKLPIEKEYYVSI 102
Parameters:
filter=none
matrix=BLOSUM62
V=50
B=50
E=10
gi
H=1
sort_by_pvalue
echofilter
ctxfactor=5.99
Query ----- As Used ----- ----- Computed ----
Frame MatID Matrix name Lambda K H Lambda K H
Std. 0 BLOSUM62 0.318 0.135 0.401
+3 0 BLOSUM62 0.318 0.135 0.401 0.326 0.142 0.425
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
+2 0 BLOSUM62 0.318 0.135 0.401 0.362 0.163 0.679
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
+1 0 BLOSUM62 0.318 0.135 0.401 0.357 0.161 0.574
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-1 0 BLOSUM62 0.318 0.135 0.401 0.349 0.155 0.515
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-2 0 BLOSUM62 0.318 0.135 0.401 0.333 0.144 0.442
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-3 0 BLOSUM62 0.318 0.135 0.401 0.357 0.157 0.572
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
Query
Frame MatID Length Eff.Length E S W T X E2 S2
+3 0 231 222 10. 77 3 12 22 0.11 35
32 0.12 38
+2 0 231 221 10. 77 3 12 22 0.11 35
32 0.12 38
+1 0 231 221 10. 77 3 12 22 0.11 35
32 0.12 38
-1 0 231 221 10. 77 3 12 22 0.11 35
32 0.12 38
-2 0 231 222 10. 77 3 12 22 0.11 35
32 0.12 38
-3 0 231 222 10. 77 3 12 22 0.11 35
32 0.12 38
Statistics:
Database: /usr/local/dot5/sl_home/beauty/seqdb/blast/nr
Title: nr
Release date: unknown
Posted date: 4:06 PM CST Feb 28, 2001
Format: BLAST
# of letters in database: 197,782,623
# of sequences in database: 625,274
# of database sequences satisfying E: 20
No. of states in DFA: 594 (59 KB)
Total size of DFA: 231 KB (256 KB)
Time to generate neighborhood: 0.02u 0.00s 0.02t Elapsed: 00:00:00
No. of threads or processors used: 6
Search cpu time: 211.49u 1.12s 212.61t Elapsed: 00:00:36
Total cpu time: 211.52u 1.16s 212.68t Elapsed: 00:00:36
Start: Mon Oct 1 23:29:18 2001 End: Mon Oct 1 23:29:54 2001
Annotated Domains Database: March 14, 2000
Release Date: March 14, 2000