Human studies
- 1,3-Butadiene. Department of Health and
Human Services (DHHS), National Institute for Occupational Safety
and Health (NIOSH) Current
Intelligence Bulletin 41, Publication No. 84-105, (1984).
- 1,3-Butadiene: inhalation
teratogenicity in the rat (final report with cover letter dated 08/11/82). International Institute of Synthetic Rubber Producers
(IISRP) (1082). Report no. 2788-522/3;
submission 8EHQ-0382-0441. Harrowgate, England: Hazleton Laboratories Europe, Ltd.
- Downs, T., S. Pier, and M. Crane. "Cause-specific mortality in a cohort of 1,000 ABS workers."
Abstr Symp. Butadiene and styrene: assessment of health
hazards.
(1992). Espoo, Finland.
- Matanoski, G.M., et al. "Epidemiologic data related to health effects
of 1,3-Butadiene. In: Assessment of inhalation hazards." Mohr, U; Bates, DV; Dungworth, DL; et al
(1989). eds. New York, NY: Springer-Verlag, 201-214.
- Delzell, E., N. Sathiakumar, and M. Macaluso. "A follow-up study of synthetic rubber workers."
(1995). Final
report prepared under contract to International Institute of Synthetic Rubber Producers.
- Matanoshi, G.M., et al. "Mortality of Workers in the Styrene-butadiene
Rubber Polymer Manufacturing Industry." (1982). A Report Prepared under Contract to the International
Institute of Synthetic Rubber Producers.
- American Journal of Epidemiology
- Monson, R.R. and K.K. Nakano. "Mortality among rubber workers. I. White male union
employees in Akron, Ohio." 103(1976): 284-296.
- Beaumon, J.J. and N.E. Breslow. "Power considerations in epidemiologic studies of vinyl chloride
workers." 114(1981):725-734.
- Downs, T.D., M.M. Crane, and K.W. Kim. "Mortality among workers at a butadiene facility."
(1987). Am J Ind Med 12:311-329.
- Duescher, R.J. and A.A. Elfarra. "Human liver microsomes are efficient catalysts for
1,3-Butadiene
oxidation: evidence for major roles by cytochrome P450 2A6 and 2E1." Archives of Biochemistry and Biophysics
311(1994):342-349.
- Malvoisin, E., M. Mercier, and M. Roberfroid. "Enzymatic hydration of butadiene monoxide and its
importance in the metabolism of butadiene." Biol Reactive Intermed II,
136A(1981):437-444.
- Carcinogenesis
- Cochrane, J.E. and T.R. Skopek. "Mutagenicity of butadiene and its epoxide metabolites: I.
Mutagenic potential of 1,2-epoxybutene, 1,2,3,4-diepoxybutane and 3,4-epoxy-1,2-butanediol in
cultured human lymphoblasts." 15(1994): 713-717.
-
Melnick, R.L. and M.C. Kohn. "Mechanistic data indicate that 1,3-butadiene is a human carcinogen."
(1995). 16(1995): 157-163.
- Maniglier-Poulet, C., et al. "Metabolism of 1,3-butadiene to butadiene
monoxide in mouse and human bone marrow cells." Chemico-Biological Interactions
97(1995):119-129.
- Environmental Health Perspectives
- Melnick, R.L., et al. "Symposium overview: toxicology, carcinogenesis, and
human health aspects of 1,3-butadiene." 86(1990): 3-5.
- Divine, B.J. "An update on mortality among workers at a 1,3-butadiene facility – preliminary
results." 86(1990): 119-128.
- Irons, R.D. "Studies on the mechanism of 1,3-butadiene-induced leukemogenesis: the potential
role of endogenous murine leukemia virus." 86(1990): 49-55.
- Ward, J.B., et al. "hprt Mutant lymphocyte frequencies in
workers at a 1,3-butadiene production plant." 1.2(1994):79-85.
- Ward, E.M., J.M. Fajen, and A. Ruder, A. "Mortality study of workers in 1,3-butadiene production units
identified from a chemical workers cohort." 103(1995):598-603.
- Ward, J.B., Jr, et al. "hprt Mutant lymphocyte frequencies in
workers at a 1,3-butadiene production plant." 102(1994): 79-85.
-
Matanoski, G.M., C. Santos-Burgoa, and L. Schwartz "Mortality of a cohort of workers in the styrene-butadiene polymer manufacturing industry (1943-1982)."
86(1990): 107-117.
- Morrow, N.L. "The industrial production and use of 1,3-butadiene."
86(1990):7-8.
- Ward, J.B., Jr, M.M. Ammenheuser, and W.E. Bechtold. "Assessment of butadiene exposure in a rubber
plant using urine metabolite and HPRT mutant frequency as biological markers of exposure and
effect." (Abstract)
Environmental and Molecular Mutagenesis
27(1996a):73.
- Acquavella, JF. "The paradox of butadiene epidemiology."
Experimental Pathology
37(1989):114.
- International Agency for Research on Cancer (IARC)
- IARC monographs on the evaluation of
carcinogenic risk of chemicals to humans. (1982). Vol. 28. The rubber industry. Lyon, France:
International Agency for Research on Cancer.
- IARC monographs on the evaluation of
carcinogenic risk of chemicals to humans. Vol. 39. Some chemicals used in plastics and
elastomers butadiene.
(1986). Lyon, France: International Agency for Research on
Cancer,
155-179.
- IARC monographs on the evaluation of
carcinogenic risks to humans. Vol. 54. 1,3-Butadiene. Occupational exposures to mists and
vapours from strong inorganic acids and other industrial chemicals. (1992). Lyon, France: International
Agency for Research on Cancer, 237-287.
- "Mutagenicity of 1,3-butadiene and its epoxide metabolites in human
TK6 cells and splenic T cells isolated from exposed B6C3F1 mice." In: Butadiene and styrene:
assessment of health hazards. Cochrane, J.E.; Skopek, T.R. (1993). IARC Scientific
Publications. Vol. 127;. Sorsa, M.; Peltonen, K.; Vainio, H.; et al, eds. Lyon, France: International Agency for Research on
Cancer, 195-204.
- Bulbulyan, M.A. et al. "Cancer incidence and mortality in a cohort of chloroprene workers from
Armenia." International Journal on Cancer
81.1(1999):
31-33.
- Duescher, R.J., and A.A. Elfarra. "1,3-Butadiene oxidation by human myeloperoxidase: role of chloride
ion in catalysis of divergent pathways." Journal of Biological Chemistry
267(1992):
19859.
- Carpenter, C.P., et al. "Studies on the inhalation of 1,3-butadiene; with a
comparison of its narcotic effect with benzol, toluol and styrene, and a note on the elimination of
styrene by the human." J Ind Hyg Toxicol. 26(1944):
69-78.
- J. Occup. Med.
- McMichael, A.J., et al. "Mortality among Rubber Workers: Relationship to
Specific Job." 18(1976): 178-185.
- Matanoski, G.M. and L. Schwartz. "Mortality of workers in styrene-butadiene polymer production."
29(1987): 675-680.
- Osterman-Golkar, S.M., et al. "Haemoglobin adducts as
biomarkers of occupational exposure to 1,3-butadiene." Mutagenesis
11(1996): 145-149.
- Kelsey, K.T., et al. "Sister-chromatid exchanges, glutathione
S-transferase
theta deletion and cytogenetic sensitivity to diepoxybutane in lymphocytes from butadiene
monomer production workers. Mutation Research/Environmental Mutagenesis
and Related Subjects
335(1995): 267-273.
- Andjelkovich, D., J. Taulbee, and M.J. Symons. "Mortality Experiences of a Cohort of Rubber Workers
1964-1973." Occup. Med.
18(1976): 387-394.
- Cowles, S.R., et al. "Mortality, morbidity, and haematologic results from a
cohort of long-term workers involved in 1,3-butadiene monomer production." Occupational and Environmental Medicine
51(1994): 323-329.
- Meimhardt, T.J., et al. "Environmental Epidemiologic Investigations of
the Styrene-butadiene Rubber Industry. Mortality Patterns with Discussion of Hematopoietic and
Lymphatic Malignancies." Scandinavian Journal of Work, Environment,
and Health
8:250-259.
- Scientific Publications
- Matanoski, G.M., M. Francis, and A. Correa-Villasenor.
"Cancer epidemiology among styrene-butadiene rubber workers. In: Butadiene and styrene: assessment of health hazards."
Scientific Publications. 127(1993).
Sorsa, M.; Peltonen, K.; Vainio, H.; et al, eds. Lyon, France: International
Agency for Research on Cancer.
- Divine, B.J., J.K. Wendt, and C.M. Hartman. "Cancer mortality among workers at a butadiene facility.
In: Butadiene and styrene: assessment of health hazards." (1993). IARC Scientific
Publications 127(1993): 345-362. Sorsa, M.; Peltonen, K.; Vainio, H.; et al, eds. Lyon, France: International Agency for
Research on Cancer.
- Toxicology
- Sorsa, M., et al. "Assessment of exposure to butadiene in the
process industry." (1996). 113(1996): 77-83.
- Tates, A.D., et al. "Biological effect monitoring in industrial workers
from the Czech Republic exposed to low levels of butadiene." 113(1996):
91-99.
- Ward, J.B., Jr., et al. "Biological monitoring for mutagenic
effects of occupational exposure to butadiene." 113(1995): 84-90.
- Delzell, E., N. Sathiakumar, and M. Hovinga. "A follow-up study of synthetic rubber workers.
113(1996): 182-189.
- Macaluso, M.; R. Larson, and E. Delzell. "Leukemia and cumulative exposure to butadiene, styrene
and benzene among workers in the synthetic rubber industry." 113(1996):
190-202.
- Divine, B.J. and C.M. Hartman. "Mortality update of butadiene production workers."
113(1996): 169-181.
- Ward, E.M., J.M. Fajen, and A. Ruder. "Mortality study of workers employed in 1,3-butadiene
production units identified from a large chemical workers cohort."
113(1996): 157-168.
-
Hayes, R.B., et al "hprt Mutation frequency among workers exposed to 1,3-butadiene in China."
113(1996): 100-105.
Animal Studies
- 1,3-Butadiene: inhalation teratogenicity study in the
rat (final report). Hazleton Laboratories Europe, Ltd. (HLE). Harrowgate, England: Hazleton Labs; addendum no. 2788-522/3.
(1981).
- The detection of dominant lethal mutations and foetal malformations, tumours and chromosome damage in the offspring of male mice treated
sub-chronically with butadiene. Anderson, D.; Edwards, A.J.; Brinkworth, M.H. (1995).
BIBRA Report No. 1060/5/95.
- Dominant lethal study in CD-1 mice
following inhalation exposure to 1,3-butadiene (final technical report). Hackett,
P.L.; McClanahan, B.J.; Mast, T.J.; et al (1988b). Richland, WA: Pacific
Northwest Laboratory; PNL no. PNL-6545 UC-408; NIH no. NIH-Y01-ES-70153; 85 p.
Prepared for NIEHS, NTP, under a Related Services Agreement with the U.S. Department of
Energy under contract DE-AC06-76RLO-1830.
- The in vivo mutagenic potential of 1,3-butadiene,
evaluated at the hprt locus of T-cells, is greater in mice than in rats exposed concurrently by
inhalation. Meng, Q.; Recio, L.; Reilly, A.A.; et al (1996). Abstract presented at the Twelfth Health Effects Institute Annual
Conference.
- Inhalation developmental toxicology studies of
1,3-butadiene in the rat (final report). Hackett, P.L.; Sikov, M.R.; Mast,
T.J.;
et al (1987a) Richland, WA: Pacific Northwest Laboratory; PNL Report
No. PNL-6414 UC-48; NIH Report No. NIH-401-ES-41031; 104 p. Prepared for NIEHS,
NTP,
under a Related Services Agreement with the US Department of Energy under contract DE-AC06-76RLO-1830.
- Inhalation developmental toxicology studies:
teratology study of 1,3-butadiene in mice (final report). Hackett, P.L.;
Sikov, M.R.; Mast, T.J.; et al (1987b) Richland, WA: Pacific Northwest
Laboratory; PNL Report No. PNL-6412 UC-48; NIH Report No. NIH-401-ES-40131; 92 p.
Prepared for NIEHS, NTP, under a Related Services Agreement with the US Department of
Energy under contract DE-AC06-76RLO-1830.
- A quantitative assessment of the
risk of cancer associated with exposure to 1,3-butadiene, based on a low dose inhalation study in
B6C3F1 mice. National Institute for Occupational Safety and Health (NIOSH)
(1991a). Submitted to the Occupational Safety and Health Administration (OSHA) for
Butadiene Docket (#H-041). US Department of Health and Human Services, Washington, DC.
- Sperm-head morphology study in
B6C3F1 mice following inhalation exposure to 1,3-butadiene (final technical
report).
Hackett, P.L.; McClanahan, B.J.; Brown, M.G.; et al (1988a). Richland,
WA: Pacific Northwest Laboratory; PNL Report No. PNL-6459 UC-48; NIH Report No. NIH-Y01-ES-70153; 51 p. Prepared for
NIEHS, NTP, under a Related Services Agreement with the
US Department of Energy under contract DE-AC06-76RLO-1830.
- Toxicological profile for 1,3
butadiene. TP-91/ 07, PB93-11690. Agency for Toxic Substances and Disease Registry
(ATSDR). Public Health Service, US Department of Health and
Human Services, Atlanta, GA (1992).
- Toxicology and carcinogenesis studies of 1,3-butadiene
(CAS No. 106-99-0) in B6C3F1 mice (inhalation studies).
National Toxicology Program (NTP), U.S. Public Health Service, US Department of Health and
Human Services (1993). NTP TR 434. Research Triangle Park, NC.
- Elfarra, A.A., R.J. Duescher, R.J., and C.M. Pasch. "Mechanisms of 1,3-butadiene oxidations to butadiene
monoxide and crotonaldehyde by mouse liver microsomes and chloroperoxidase."
Archives of Biochemistry and Biophysics
286(1991):
244-251.
- Laib, R.J., et al. "Pharmacokinetic interaction between 1,3-butadiene and
styrene in Sprague-Dawley rats." Arch Toxicol
66(1992): 310-314.
- Melnick, R.L.,
et al. "Isoprene, an endogenous hydrocarbon and industrial chemical,
induces multiple organ neoplasia in rodents after 26 weeks of
inhalation exposure." Cancer Res
54(1994): 5333-5339.
- Carcinogenesis
- Thornton-Manning, J.R., et al. "Gender differences in the metabolism of
1,3- butadiene in Sprague-Dawley rats following low-level inhalation exposure."
16(1995): 2875-2878.
-
Medinsky, M.A., et al. "In vivo metabolism of butadiene by mice and
rats: a comparison of physiological model predictions and experimental data."
15(1994):1329-1340.
-
Himmelstein, M.W., et al. "Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation."
15(1994): 1479-1486.
- Thornton-Manning, J.R., et al. "Disposition of butadiene monoepoxide
and butadiene diepoxide in various tissues of rats and mice following a low-level inhalation
exposure to 1,3-butadiene." 16(1995): 1723-1731.
- Cochrane, J.E. and T.R. Skopek. "Mutagenicity of butadiene and its epoxide metabolites: II.
Mutational spectra of butadiene, 1,2-epoxybutene, and diepoxybutane at the hprt locus in splenic
T cells from exposed B6C3F1 mice." 15(1994): 719-723.
- Chemical Research in Toxicology
- Nauhaus, S.K., et al. "Characterization of urinary metabolites from Sprague-Dawley rats and B6C3F1 mice exposed to
[1,2,3,4-C-13] butadiene." 9(1996): 764-773.
- Elfarra, A.A., J.E. Sharer, and R. J. Duescher. "Synthesis and characterization of
N-acetyl-L-cysteine S-conjugates of
butadiene monoxide and their detection and quantitation in urine of rats
and mice given butadiene monoxide." 8(1995): 68-76.
- Oe T.; et al. "Persistence of N7-(2,3,4-trihydroxybutyl)guanine adducts in the livers of
mice and rats exposed to 1,3-butadiene." 12.3(1999): 247-257.
- Richardson K.A., et al. "Identification of novel metabolites of butadiene monoepoxide in
rats and mice." 11.12(1998): 1543-1555.
- Sharer, J.E., R.J. Duescher, and A.A. Elfarra. "Species and tissue differences in the microsomal
oxidation of 1,3- butadiene and the glutathione conjugation of butadiene monoxide in mice and
rats." Drug Metab Dispos 20(1992):658- 664.
- Environmental Health Perspectives
- Laib, R.J., et al. "Inhalation pharmacokinetics of 1,3-butadiene and 1,2-epoxybutene-3 in rats and mice."
86(1990): 57-63.
- Melnick, R.L., et al. "Inhalation toxicology and carcinogenicity of 1,3-butadiene in B6C3F1 mice following 65 weeks of exposure."
86(1990c): 27-36.
- Evelo, C.T.A., et al. "Physiologically based toxicokinetic
modeling of 1,3- butadiene lung metabolism in mice becomes more important at low doses."
(1993). 101(1993):
496-502.
-
Anderson, D., A.J. Edwards, A.J.; Brinkworth, M.H. "Male-mediated F1 effects in mice exposed to 1,3-butadiene. In: Butadiene and styrene: assessment of health hazards."
(1993). IARC Scientific
Publications. Vol. 127. Sorsa, M.; Peltonen, K.; Vainio, H.; et al, eds. Lyon, France: International
Agency for Research on Cancer, 171-181.
- 1,3-Butadiene induces cancer in experimental animals at all
concentrations from 6.25 to 8,000 parts per million. In: Butadiene and styrene: assessment of
health hazards. Melnick, R.L.; Huff, J.E. (1993). IARC
Scientific.
-
Bolt, H.M., et al. "Biological activation of 1,3-butadiene to vinyl oxirane
by rat liver microsomes and expiration of the reactive metabolite by exposed rats." J Cancer Res
Clin Oncol. 106(1983): 112-116.
- Mutation Research
- Adler, I.D., et al. "Heritable translocations induced by inhalation exposure
of male mice to 1,3-butadiene." 347(1995): 121-127.
- Adler, I.D. and D. Anderson. "Dominant lethal effects after inhalation exposure to 1,3-butadiene."
309(1994): 295-297.
- Adler, I.D., et al. "Mutagenicity of 1,3-butadiene inhalation in somatic and
germinal cells of mice. 309(1994): 307-314.
- Kligerman A.D.; et al. "Comparison of cytogenetic effects of 3,4-epoxy-1-butene and 1,2:3, 4-diepoxybutane in mouse, rat and human lymphocytes following in vitro G0
exposures." 439.1(1999): 13-23.
- Filser, J.G., et al. "Metabolism of 1,3-butadiene in microsomes from livers
of mouse, rat, and man." Naunyn-Schmiedeberg's Arch Toxicol Suppl.
345.R31(1992).
- Toxicology and Applied Pharmacology
- Dahl, A.R., et al. "The fate of isoprene inhaled by rats: comparison to
butadiene." 89(1987): 237-242.
- Himmelstein, M.W., B. Asgharian, and J.A. Bond. "High concentrations of butadiene epoxides in livers
and lungs of mice compared to rats exposed to 1,3-butadiene." 132(1995):
281-288.
- Irons, R.D., et al. "Macrocytic-megaloblastic anemia in male NIH
Swiss mice following repeated exposure to 1,3-butadiene. 85(1986): 450-455.
- Dahl, A.R., et al. "Toxicokinetics of inhaled 1,3-butadiene in monkeys:
comparison to toxicokinetics in rats and mice." 110(1991): 9-19.
-
Irons, R.D., et al. "Susceptibility to 1,3-butadiene-induced
leukemogenesis correlates with endogenous ecotropic retroviral background in the mouse."
101(1989): 170-176.
- Toxicology Letters
- Deutschmann, S. and R.J. Laib. "Concentration-dependent depletion of non-protein sulfhydryl (NPSH)
content in lung, heart and liver tissue of rats and mice after acute inhalation exposure to
butadiene." 45(1989):175-183.
- Kreiling, R., R.J. Laib, and H.M. Bolt. "Depletion of hepatic non-protein sulfhydryl content during
exposure of rats and mice to butadiene." 41(1988): 209-214.
- Recio, L. and T.L. Goldsworthy. "The use of transgenic mice for studying mutagenicity induced by
1,3- butadiene." 82(1995): 607-612.
-
Thornton-Manning, J.R., et al. "Tissue concentrations of butadiene
epoxides in rodents following multiple and single exposures to 1,3-butadiene (BD) by inhalation."
Toxicologist 30(1996):215.
- Toxicology
- Dunnick, J.K., et al. "Respiratory tract lesions in F344/N rats and
B6C3F1 mice after inhalation exposure to 1,2-epoxybutane." 50(1988): 69-82.
- Doerr, J.K., E.A. Hollis, and I.G. Sipes. "Species difference in the ovarian toxicity of 1,3-butadiene
epoxides in B6C3F1 mice and Sprague-Dawley rats." 113(1996): 128-136.
-
Irons, R.D., W.S. Stillman, M.W. Cloyd. "Selective activation of endogenous ecotropic retrovirus in
hematopoietic tissues of B6C3F1 mice during the preleukemic phase of 1,3-butadiene exposure." Virology
161(1987): 457- 462.
Other
- Locating and estimating air emissions from
sources of 1,3- butadiene. Environmental Protection Agency (EPA), Office of Air
Quality Planning and Standards, (1994a).
- Memo from Rich Cook, Office of Mobile
Sources to Dennis Beauregard. Environmental Protection Agency (EPA), Office of Air Quality Planning and
Standards, (1994b) (November 9, 1994).
- Occupational exposure to 1,3-butadiene; final
rule. Occupational Safety and Health Administration
(OSHA), (1996,
November 4). Federal Register
61(214):56745-56795.
- Occupational exposure to 1,3-butadiene; proposed rule and notice of
hearing. Occupational Safety and Health Administration (OSHA), (1990,
August 10). Federal
Register 55:32736-32776.
- Pharmacokinetic/mechanism-based analysis of the carcinogenic risk of
butadiene. PB88-20817. Hattis, D.; Wasson, J., (1987). Rockville, MD: National Institute for Occupational Safety and Health,
1-122.
- Proposed identification of 1,3-butadiene as a toxic air
contaminant. California Air Resources Board, (1991). Prepared by the Office of Environmental Health Hazard Assessment. Sacramento,
CA.
- Proposed identification of 1,3-butadiene as a toxic air
contaminant. Part A. Exposure assessment. California Air Resources Board. Stationary Source Division, Sacramento,
CA, (1992).
- Proposed guidelines for carcinogen risk
assessment. Environmental Protection Agency (EPA), (1996, April 23). Federal Register 61(79):17960-18011.
- Review of sources and emission estimates for
1,3-butadiene. Ligocki, M.P., (1993). SYSAPP-93/074.
Prepared by Systems Applications International, Inc., San Rafael, CA.
- A survey of exposures to gasoline vapour. Report No. 4/87. Concawe,
(1987). de Hague: Concawe.
-
Toxicological profile for 1,3-butadiene. Department of Health and Human Services
(DHHS), Public Health
Service, (1992).
- The use of the benchmark-dose approach in
health risk assessment. Environmental Protection Agency (EPA), Office of
Research and Development, EPA/630/R-94/007, (1995).
- American Industrial Hygiene Association
Journal
- Bond, J.A., et al. "Species differences in the distribution of butadiene in
tissues." 48(1987): 867-872.
- Checkoway, H. and T.M. Williams. "A hematology survey of workers at a styrene-butadiene
synthetic rubber manufacturing plant." 4.3(1982): 164-169.
- Jelitto, B., R.R. Vangala, and R.J. Laib. "Species differences in DNA damage by butadiene: role of
diepoxybutane. Archives of Toxicology 13(1989):
246-249.
- Hallenbeck, W. "Cancer risk assessment for the inhalation of 1,3-butadiene using physiologically
based pharmacokinetic modelling." Bulletin of Environment Contamination and
Toxicology
49(1992):66-70.
- Goodrow, T., et al. "Activation of K-ras by codon 13 mutations in
C57BL/6 × C3HF1 mouse tumors induced by exposure to 1,3-butadiene." Cancer Res
50(1990): 4818-4823.
-
Carcinogenesis
- Brunnemann, K.D., et al. "Analysis of 1,3-butadiene and other selected gas-phase components in cigarette mainstream and sidestream smoke by gas chromatography-mass
selective detection." 11(1990): 1863.
- Kohn, M.C. and R.L. Melnick. " Species differences in the production and clearance of 1,3-butadiene
metabolites: a mechanistic model indicates predominantly physiological, not biochemical,
control.
14(1993):619-628.
- Bechtold, W.E., et al. "Analysis of butadiene, butadiene
monoxide and butadiene diepoxide in blood by gas chromatography/gas chromatography/mass
spectroscopy." Chemical Research in Toxicology
8(1995): 182-187.
- Anon. "Chemical profile: butadiene." Chem Mark Rep
239(1991): 50.
- Csanády, G.A. and J.A. Bond. "Species differences in the biotransformation of 1,3-butadiene to DNA-reactive
epoxides: role in cancer risk assessment. Chemical Industry Institute of Toxicology,
CIIT Activities 11(1991): 1-8.
- Himmelstein, M.W., et al. "Toxicology and epidemiology of 1,3-butadiene."
Crit Rev Toxicol, 27.1(1997):1-108.
- Cole, P., E. Delzell, and J. Acquavella. "Exposure to butadiene and lymphatic and hematopoietic
cancer." Epidemiology 4(1993):86.
- Dahl, A.R., et al. "Species differences in the metabolism and disposition
of inhaled 1,3-butadiene and isoprene." Environmental Health Perspectives
86(1990):65-69.
-
Rosenthal, S.L. "The reproductive effects assessment group's report on the mutagenicity of 1,3-butadiene and its reactive metabolites." Environ Mutagen
7(1985): 933-945.
- Crump, K.S. "A new method for determining allowable daily intakes."
Fundam Appl Toxicol 4(1984): 854-871.
- Norppa, H. and M. Sorsa. "Genetic toxicology of 1,3-butadiene and styrene. In: Butadiene and
styrene: assessment of health hazards." (1993). IARC Scientific Publications. Vol. 127. Sorsa,
M.;
Peltonen, K.; Vainio, H.; et al, eds. Lyon, France: International Agency for Research on Cancer,
185-193.
- Nordlinder, R.G., R.I. Nilsson, and A.B. Buskhe. "1,3-butadiene in gasoline: an analytical conclusion." J
Occup Environ Med. 38(1996):463.
- Andjelkovich, D., J. Taulbee, and M. Symons. "Mortality of rubber workers with reference to work
experience." J Occup Med 19(1997): 397-405.
- Mutat Res
- De Meester, C. "Genotoxic properties of 1,3-butadiene." 195(1988): 273-281.
- Jacobson-Kram, D. and S. Rosenthal. "Molecular and genetic toxicology of 1,3-butadiene."
339(1995): 121- 130.
- Andjelkovich, D., J. Taulbee, and M.J. Symons. "Mortality experience of a cohort of rubber workers,
1964-1973." Occup Med 18(1976):387-394.
- Bond, J.A. and G.A. Csanády. "Species and organ differences in the in vitro metabolism of butadiene to
butadiene monoepoxide." Proc Am Assoc Cancer
Res 32(1991): 119.
- Toxicology and Applied Pharmacology
- Bond, J.A., et al. "Species differences in the disposition of inhaled
butadiene." 84(1986): 617-627.
- Bechtold, W.E., et al. "Species differences in urinary metabolite ratios
between mice, rats, and humans."
127(1994): 44-49.
|
