CENTERS OF RESEARCH ON APPLIED GERONTOLOGY NIH GUIDE, Volume 21, Number 29, August 14, 1992 RFA AVAILABLE: AG-93-02 P.T. 04 Keywords: Aging/Gerontology Behavioral/Social Studies/Service Sociology National Institute on Aging Letter of Intent Receipt Date: October 2, 1992 Application Receipt Date: November 18, 1992 THE REQUEST FOR APPLICATIONS (RFA) ANNOUNCED IN THIS NOTICE CONTAINS ESSENTIAL INFORMATION FOR THE PREPARATION OF AN APPLICATION. POTENTIAL APPLICANTS MAY OBTAIN THE RFA FROM THE CONTACT NAMED IN INQUIRIES, BELOW. PURPOSE This announcement seeks to establish Centers of Research on Applied Gerontology. The Centers' purpose will be to facilitate the process of translating basic behavioral and social research theories and findings into practical outcomes that will benefit the lives of older people. They will focus on strategies to improve quality of life, enhance productivity, and minimize the need for care. HEALTHY PEOPLE 2000 The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2000," a PHS-led national activity for setting priorities. This RFA, Centers of Research on Applied Gerontology, addresses several priority areas including chronic disabling conditions, physical activity and fitness, violent and abusive behavior, and unintentional injuries as they relate to older people. Potential applicants may obtain a copy of "Healthy People 2000" (Full Report: Stock No. 017-001-00474-0) or "Healthy People 2000" (Summary Report: Stock No. 017-001-00473-1) through the Superintendent of Documents, Government Printing Office, Washington, DC 20402-9325 (telephone 202/783-3238). ELIGIBILITY REQUIREMENTS Domestic public and private, for-profit and non-profit institutions and organizations are eligible to apply in response to this RFA, provided that some member of the proposed research team at the institution has recently received grant or contract funds or is currently active in research through an external peer-reviewed process in the three years preceding the date of application. Applications from women and minority investigators and institutions are encouraged. Awards will not be made to foreign institutions. MECHANISM OF SUPPORT The support mechanism for these Centers will be the specialized center (P50) mechanism. Such awards cover a spectrum of activities that comprise a multidisciplinary attack on a particular problem area. A maximum of five years of support may be requested. At that time funds may be available for competitive renewal of the Centers. All current policies and requirements that govern the research grant programs of the NIH will apply to grants awarded in connection with this RFA. Special Terms of Awards applying to projects funded in response to this RFA are in addition to, and not in lieu of, otherwise applicable OMB administrative guidelines, HHS grants administrative regulations at 45 CFR Part 74, and other HHS, PHS, and NIH grants administration policies. Awardees will maintain custody of and primary rights to their data developed under their awards, subject to Government rights of access, consistent with current HHS, PHS, and NIH policies. FUNDS AVAILABLE An estimated $3,000,000 will be made available in Fiscal Year 1993 for support of awards made under this RFA. It is expected that up to six awards will be made at a maximum of $400,000 direct costs per award for the first year. This level of support is dependent on the receipt of a sufficient number of applications of high scientific merit. Awards pursuant to the RFA are contingent upon the availability of funds for this purpose. Commitment from the applicant will be considered in making final awards. RESEARCH OBJECTIVES Researchers are encouraged to seek funding to apply the theories, paradigms, and methodology of the behavioral and social sciences in order to address practical problems of late middle aged and older people at work, in the home, in transportation, in health care, or in other areas of concern to the population. The focus of this initiative is on translating encouraging research results obtained in laboratory and other scientific settings into practical benefits for older adults. The organizing principle behind each Center should reflect this aim of establishing a pattern of research translation from basic research to practical outcome. The individual projects that are part of the Center should have as the goal a practical end-point---improvement in some indicator or indicators of functioning in these different environments. Improvements in aspects of behavioral indicators relevant to the practical domain (e.g., laboratory measures of cognitive functioning, health status, or subjective well-being) may be considered interim goals of the research strategy. However, the end-point is improvement in functioning in the practical domain itself. Thus the goal will not only be confirming a theory or discovering a new effect (though these may be expected from well-designed studies addressing practical problems). One highly desirable feature of the Centers will be a focus on special populations of older people. Growth in size of minority older populations has been, and will continue to be, substantial. The oldest old remain the population at greatest risk for dependency. Older adults who have been identified as retarded face particular problems in later life. Poor older adults in rural areas have severely limited access to health care and general services. These and other special populations who have pressing needs warrant attention from researchers in aging. SPECIAL REQUIREMENTS Annual Meeting Investigators are encouraged to request funds to travel once each year to meet with the other investigators who are funded through this RFA. The meetings will be held at the NIH, Bethesda, MD. The purpose of the meetings is to have investigators working in the same general area share information about research methods and findings. Applicants should include a statement in the application indicating a willingness to participate in such meetings and to cooperate with other researchers in the exchange of data, materials, and ideas. STUDY POPULATIONS SPECIAL INSTRUCTIONS FOR INCLUSION OF WOMEN AND MINORITIES IN CLINICAL RESEARCH STUDY POPULATIONS For projects involving clinical research, the NIH requires applicants to give special attention to the inclusion of women and minorities in study populations. if women or minorities are not included in the study populations for clinical studies, a specific justification for this exclusion must be provided. Applications without such documentation will not be accepted for review. LETTER OF INTENT Prospective applicants are asked to submit, by October 2 1992, a letter of intent that includes identification of other participating investigators and institutions and a descriptive title. The NIA requests such letters only for the purpose of providing an indication of the number and scope of applications to be received and, therefore, usually does not acknowledge their receipt. A letter of intent is not binding, and it will not enter into the review of any application subsequently submitted, nor is it a necessary requirement for application. The letter of intent is to be sent to Dr. Robin A. Barr at the address under INQUIRIES. APPLICATION PROCEDURES The research grant application form PHS 398 (rev. 9/91) is to be used in applying for these grants. This form is available in the applicant institution's office of sponsored research or business office and from the Office of Grants Inquiries, National Institutes of Health, Room 449, Westwood Building, Bethesda, MD 20892-9912, telephone (301) 496-7441. REVIEW CONSIDERATIONS Upon receipt, the Division of Research Grants will review applications for completeness and NIA staff will review applications for responsiveness. Applications that are incomplete, nonresponsive to this RFA, or exceed the annual direct cost limit of $400,000 (including total costs for sub-contracts) will be returned to the applicant without further consideration. The NIA will withdraw from further competition those applications judged by triage to be noncompetitive for award and notify the applicant and institutional official. Applications judged to be competitive will undergo further scientific merit review by an initial review group within the NIA. This review may involve an applicant interview or site visit. The second level of review will be provided by the National Advisory Council on Aging. The most important criterion for scientific merit review will be the proposed Center's demonstrated potential to act as a conduit between basic behavioral and social research and applied outcomes. Both the evidence of past involvement in related research and the specific plans for seeking applied outcomes described in the application will be considered part of that potential. A related and important criterion concerns the proposed Center's ability to address the needs of special populations of older people who are identified as having particularly pressing concerns. INQUIRIES Inquiries concerning this RFA are encouraged in order to clarify issues or questions. The RFA may be obtained from the program contact listed below who will also answer questions on programmatic issues related to the RFA: Dr. Robin A. Barr Behavioral and Social Research National Institute on Aging Gateway Building, Room 2C234 7201 Wisconsin Avenue Bethesda, MD 20892 Telephone: (301) 496-3136 FAX: (301) 402-0051 E-mail: Barr@NIHNIAGW.BITNET Questions on fiscal matters should be directed to: Ms. Linda Whipp Grants and Contracts Management National Institute on Aging Gateway Building, Room 2N212 7201 Wisconsin Avenue Bethesda, MD 20892 Telephone: (301) 496-1472 AUTHORITY AND REGULATIONS This program is described in the Catalog of Federal Domestic Assistance, No. 93.866. Awards are made under the authority of the Public Health Service Act, Section 301 (42 USC 241) and administered under PHS grants policies and Federal Regulations, most specifically at 42 CFR Part 52 and 45 CFR Part 74. This program is not subject to the intergovernmental review requirements of Executive Order 12372 or Health Systems Agency review. .