Interventional Biology Group.

Publications (Peer reviewed)

Fouzi Mouffouk, Yasmin Chishti, Qiaoling Jin, Michelle E. Rosa, Melixa Rivera, Siva Dasa and Liaohai Chen  “Polymeric micelle-based bioassay with femtomolar sensitivity”  Analytical Biochemistry, (2008) 372, 140

John Bahns, A. Imre, V. K. Vlasko, Liaohai Chen, U. Welp , "Enhanced Raman scattering from focused surface plasmons", Appl. Phys. Lett., (2007) 91, 081104-1

Lydia Finney, Stefan Vogt, Tohru Fukai and David Glesne.  Copper and angiogenesis: unraveling a relationship key to cancer progression.  Clinical and Experimental Pharmacology and Physiology.  Invited review, submitted.

Lydia Finney, S. Mandava, L. Ursos, W. Zhang, D. Rodi, Stefan Vogt, D. Legnini,  J. Maser, F. Ikpatt, O. Olufunmilayo, and David Glesne.  X-Ray Fluorescence Microscopy Reveals Large-scale Relocalization and Extracellular Transport of Cellular Copper During Angiogenesis. PNAS, ( 2007) 104, 7, 2247-2252.

Yuexing Zhang, John T. Bahns, Qiaoling Jin, Ralu Divan, and Liaohai Chen, "Toward the detection of single virus particle in serum", Anal Chem., (2006) 356, 161-170.

John T. Bahns, Funing Yan, Dengli Qiu, Rong Wang and Liaohai Chen,"Hole-Enhanced Raman Scattering", Appl. Spectrosc. (2006) 60, 989-993.

Chin-Mei Liu, Qiaoling Jin, April Sutton, and Liaohai Chen, "A novel fluorescent probe: Europium complex hybridized T7 phage", Bio-conjugation Chem., (2005)16, 1054 -1057.

K. E. Achyuthan, T. S. Bergstedt, Liaohai Chen, R. M. Jones, S. Kumaraswamy, S. A. Kushon, K. D. Ley, L. Lu, D. McBranch, H. Mukundan, F. Rininsland, X. Shi, W. Xia and D. G. Whitten, "Fluorescence superquenching of conjugated polyelectrolytes: applications for biosensing and drug discovery", Journal of Materials Chemistry, (2005) 15, 2648–2656.

S.-H. Chung, A. Hoffmann, K. Guslienko, S. D. Bader, C. Liu, B. Kay, L. Makowski, and Liaohai. Chen, " Biological sensing with magnetic nanoparticles using Brownian relaxation" (invited), J. Appl. Phys., (2005) 97, 10R101.

Qiling Tang, Yuexing Zhang, Liaohai Chen, Funing Yan and Rong Wang, "Protein delivery with nanoscale precision", Nanotechnology, (2005) 16, 1062-1068.

J. Dalvi-Malhotra and Liaohai Chen, "Enhanced Conjugated Polymer Fluorescence Quenching by Dipyridinium-Based Quenchers in the Presence of Surfactant", J. Phys. Chem. B., (2005) 109(9), 3873-3878.

Funing Yan, Qiling Tang, Rong Wang, and Liaohai Chen, "Synthesis and characterization of a photo-cleavable cross-linker and its application on tunable surface modification and protein photo-delivery", Bio-conjugation Chem., (2004) 15,1030-1036.

John T. Bahns, Chin-Mei Liu, and Liaohai Chen, "Characterizing specific phage-protein interactions by fluorescence correlation spectroscopy", Protein Science, (2004) 13, 2578-2587.

S. H.  Chung, A. Hoffmann, S. D. Bader, C. Liu, B. Kay, L. Makowski, and Liaohai Chen, "Biological sensors based on Brownian relaxation of magnetic nanoparticles", Apply Phys. Lett., (2004) 85, 2971-2973.

Rong Wang, Jeane Shi, Atul N. Parikh, Andrew P. Shreve, Liaohai Chen, and Basil I. Swanson, "Evidence for cholera aggregation on GM1-decorated lipid bilayers", Colloids and Surfaces B: Biointerfaces, (2004) 33, 45-51.

Steen Rasmussen, Liaohai Chen, Barbel Stadler, and Peter Stadler, "Proto-organism kinetics: evolutionary dynamics of lipid aggregates with gene and metabolism", Origins of Life and Evol. of The Biosp., (2004) 34, 171.

Steen Rasussen, Liaohai Chen, David Deamer, David Krakauer, Norman Packard, Peter Stadler and Mark Bedau, "Transitions from nonliving to living Matter", Science, (2004) 303, 963-965.

Steen Rasmussen, Liaohai Chen, Martin Nilsson, and Shigeaki Abe, "Bridging Nonliving and Living Matter", Artificial Life, (2003) 9, 269-316.

Shigeaki Abe and Liaohai Chen, "Tuning the photophysical properties of an ionic conjugated polymer through interaction with polyelectrolytes", J. Polymer science: Part B: polymer physics, (2003) 41, 1676-1679.

Hsing-lin Wang, Duncan McBranch, Liaohai Chen, and Fred Wudl, "Highly efficient energy and charge transfer in thin self-assembled mutilayered polymer films", Synthetic Metals, (2001) 121, 1367.

Patents

Liaohai Chen, A. Hoffmann, S. D. Bader, B. Kay and L. Makowski, "Inorganic hybridized phage",  US patent filed March 21, 2005

Chen, Liaohai, "Enhanced photophysics of conjugated polymers", US patent (2003) 0224525.

Chen, Liaohai; Xu, Su; McBranch, Duncan; Whitten, David. "Enhanced photophysics of conjugated polymers, complex with surfactants, their manufacture and fluorescent propertie" US Patent (2003) 6569952.

Chen, Liaohai,  "Tuning the properties of ionic conjugated polymer with polyelectrolytes and application in a biosensor platform".  Patent number WO (2002) 2002079268.

Chen, Liaohai; McBranch, Duncan W.; Wang, Hsing-Lin; Whitten, David G.  "Method for detecting biological agents". Patent number  WO (2000) 2000066790.  The patent has led to the establishment of QTL Biosystems at Santa Fe, New Mexico and the sensor device was the candidate for 2000 R&D 100 award.

Book Chapters

Axel Hoffmann, Seok-Hwan Chung, Samuel D. Bader, Lee Makowski and Liaohai Chen, Chapter 1, BROWNIAN MOTION IN BIOLOGICAL SENSING.  BIOMEDICAL APPLICATIONS OF NANOTECHNOLOGY, A JOHN WILEY & SONS, INC., 2005