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| Sponsors and Collaborators: |
Lawson Health Research Institute Canada Foundation for Innovation Pfizer |
|---|---|
| Information provided by: | Lawson Health Research Institute |
| ClinicalTrials.gov Identifier: | NCT00669006 |
Purpose
To establish the infrastructure for a national neuropathic pain database.
To determine the longterm outcome of the management of chronic neuropathic pain including pain relief, disability, and quality of life.
| Condition |
|---|
|
Neuropathic Pain |
| Study Type: | Observational |
| Study Design: | Case-Only, Prospective |
| Official Title: | National Neuropathic Pain Database Study |
| Estimated Enrollment: | 900 |
| Study Start Date: | April 2008 |
| Estimated Study Completion Date: | July 2011 |
| Estimated Primary Completion Date: | May 2011 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
|
1
New patients with a diagnosis of Neuropathic Pain
|
The database will provide standard information on demographics, diagnosis, treatment interventions and outcome modeled on guidelines from the expert panel on initiatives on Methods, Measurement and Pain Assessment in Clinical Trials (IMMPACT)(Turk et al.,Pain 2003;106:337-345) The IMMPACT panel determined that patients should be evaluated according to six core domains as follows: Pain, physical functioning, emotional functioning, subject rating of global satisfaction with treatment, symptoms and adverse events and subject disposition.
The database will allow us to examine outcomes based on single (eg. pregabalin) and multiple (e.g tricyclic antidepressants and gabalin) therapeutic interventions. Standard guidelines for management of neuropathic pain acknowledge that polypharmacy is appropriate when individual first line treatments fail to provide adequate pain relief (Gilron I et al., CMAJ 2006; 175: 265-275; Attal N et al., European Journal of Neurology 2006; 13: 1153-1169)
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Probability Sample |
New patients referred to the outpatient pain clinic with a diagnosis of Neuropathic Pain.
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Dwight Moulin, MD | 519-685-8500 ext 58661 | dwight.moulin@lhsc.on.ca |
| Contact: Charlene M Bartha, RN | 519-685-8500 ext 74819 | charlene.bartha@lhsc.on.ca |
| Canada, Ontario | |
| London Health Sciences Centre- St. Joseph's Health Care | Recruiting |
| London, Ontario, Canada, N6A 4V2 | |
| Contact: Dwight Moulin, MD 519-685-8661 dwight.moulin@lhsc.on.ca | |
| Contact: Charlene M Bartha, RN 519-685-8500 ext 74819 charlene.bartha@lhsc.on.ca | |
| Principal Investigator: Dwight Moulin, MD | |
| Principal Investigator: | Dwight Moulin, MD | London Health Sciences Centre- St. Joseph's Health Care |
More Information
| Responsible Party: | Lawson Health Research Institute ( Dr. Dwight Moulin ) |
| Study ID Numbers: | R-07-835, 13930E |
| Study First Received: | April 28, 2008 |
| Last Updated: | April 28, 2008 |
| ClinicalTrials.gov Identifier: | NCT00669006 |
| Health Authority: | Canada: Ethics Review Committee |
|
neuropathic pain database prospective national |
|
Pain |
