FRESH-02 / STS-107
Title of Study
Choroidal Regulations Involved in the Cerebral Fluid Response to Altered Gravity: Water Transports and Serotonergic Receptors
Science Discipline
Interdisciplinary physiology
Investigator |
Institute |
Jacqueline B. Gabrion |
University of Pierre and Marie Curie, France |
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Co-Investigator(s) |
Institute |
None |
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Rattus norvegicus (Sprague-Dawley rat)
Flight: 8 Male
Ground Based Controls
Asynchronous: 8
Vivarium: 8
Ambient Temperature Recorder, Animal Enclosure Module
Objectives/Hypothesis
The process of adapting to microgravity is well known to change the distribution of fluids in the body, including the brain, kidneys, and lungs. In all of these organs, a family of proteins called aquaporins transport water. This study was designed to investigate the effect of space flight on aquaporins.
Approach or Method
It was planned that immediately postflight, the brains, pituitary glands, kidneys, and lungs of eight mature, male rats would be removed, processed, and analyzed using conventional electron microscopy and immunocytochemistry detection.
Results
The payload was not recovered.
Publications
Not applicable.