| US 7,348,332 B2 | ||
| (3,4-dihydro-quinazolin-2-yl)-indan-1-yl-amines | ||
| Alexander Alanine, Schlierbach (France); Luca Claudio Gobbi, Overwil (Switzerland); Sabine Kolczewski, Rheinfelden (Germany); Thomas Luebbers, Loerrach (Germany); Jens-Uwe Peters, Grenzach-Wyhlen (Germany); and Lucinda Steward, Basel (Switzerland) | ||
| Assigned to Hoffmann-La Rochse Inc., Nutley, N.J. (US) | ||
| Filed on Apr. 05, 2006, as Appl. No. 11/399,790. | ||
| Claims priority of application No. 05102824 (EP), filed on Apr. 11, 2005. | ||
| Prior Publication US 2006/0229323 A1, Oct. 12, 2006 | ||
| Int. Cl. A61K 31/517 (2006.01); C07D 239/84 (2006.01) | ||
| U.S. Cl. 514—266.21 [514/266.24; 514/266.4; 544/284; 544/292] | 19 Claims |
1. A compound of formula I
 R1 is hydrogen, lower alkyl, lower alkoxy, halogen or lower alkyl substituted by halogen;
R2 is hydrogen, lower alkyl, aryl which is optionally substituted by one or more substituents selected from the group consisting
of lower alkyl and halogen, or is thiophenyl or isoxazole; and
n is 1 or 2; or a pharmaceutically acceptable acid addition salt thereof.
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