Qiu, Y., Zhao, Y., Becker, M., John, S., Parekh, B.S., Huang, S., Hendarwanto, A., Martinez, E.D., Chen, Y., Lu, H., Adkins, N.L., Wiench, M., Georgel, P.T., Schiltz, R.L., and Hager, G.L. HDAC1 acetylation is linked to progressive modulation of steroid receptor induced gene transcription. Mol Cell 22 (5) 669-679 2006 Voss, T.C., John, S., and Hager, G.L. Single cell analysis of glucocorticoid receptor action reveals that stochastic post-chromatin association mechanisms regulate ligand-specific transcription. Mol Endocrinol. 20(11) 2641-2655 2006 Hager, G.L., Elbi, C., Johnson, T.A., Voss, T., Nagaich, A.K., Schiltz, R.L., Qiu, Y., John, S. Chromatin dynamics and the evolution of alternate promoter states. Chromosome Res. 14 107-116 2006 Hager, G.L., and Nagaich, A.K. Transcription factor dynamics. In: Gene Expression and Regulation. J.Ma, ed. New York; Beijing: Springer; Higher Education Press. pp 493-502, 2006 Martinez, E.D., Dull, A.B., Beutler, J.A., and Hager, G.L. High-content fluorescence-based screening for epigenetic modulators. In: Measuring Biological Responses with Automated Microscopy J. Inglese, ed., Methods in Enzymology 414 21-36, 2006 Martinez, E.D., and Hager, G.L. Development of assays for nuclear receptor modulators using fluorescently tagged proteins. In: Measuring Biological Responses with Automated Microscopy J. Inglese, ed., Methods in Enzymology 414 37-50, 2006 Marom, R., Shur, I., Hager, G.L., and Benayahu, D. The expression and regulation of CReMM, a chromodomain helicase-DNA-binding protein in stromal osteoprogenitor cells. J.Cell Physiol. 207 (3) 628-635 2006 Rayasam, G.V., Elbi, C., Walker, D.A., Wolford, R., Fletcher, T.M., Edwards, D.P., and Hager, G.L. Ligand specific dynamics of the progesterone receptor in living cells and during chromatin remodeling in vitro Mol Cell Biol. 25 2406-2418 2005 Cremazy, F.G.E., Manders, E.M.M., Bastiaens, P.I.H., Kramer, G., Hager, G.L., van Munster, E.B., Verschure, P.J., Gadella, T.W.J., and van Driel, R. Imaging in situ protein-DNA interactions in the cell nucleus using FRET-FLIM. Exp Cell Res. 309 390-396 2005 Elbi, C., Walker, D.A., Lewis, M., Romero, G., Sullivan, W.P., Toft, D.O., Hager, G.L., DeFranco, D.B. A novel in situ assay for the indentification and characterization of soluble nuclear mobility factors. Sci STKE 2004. June 22;2004 (238): PL10. Nagaich, A.K., Walker, D.A., Wolford, R., Hager, G.L. Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling. Mol Cell 23;14 (2) 163-74 2004 Stavreva, D.A., Mueller, W.G., Hager, G.L., Smith, C.L., McNally, J.G.Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes. Mol Cell Biol.24;(7) 2682-97 2004 Elbi, C., Walker, D.A., Romero, G., Sullivan, W.P., Toft, D.O., Hager, G.L., DeFranco, D.B. Molecular chaperones function as steroid receptor nuclear mobility factors. Proc Natl Acad Sci USA. 101;(9) 2876-81 2004. Epub 2004 Feb 20 Nagaich, A.K., and Hager, G.L. UV Laser cross-linking: A real-time assay to study dynamic protein/DNA interactions during chromatin remodeling Science STKE 256 PL13 2004 Lawrence,J.B. and Hager,G.L.Nucleus and gene expression: Motion meets architecture Curr.Opin.Cell Biol. 15 255-258 2003 Rayasam,G.V., Wendling,O., Angrand,P.O., Mark,M., Niederreither,K., Song,L., Lerouge,T., Hager,G.L., Chambon,P., and Losson,R.NSD1 is essentail for early post-implantation development and has a catalytically active SET domain. EMBO J.22 3153-3163 2003 Georgel,P.T., Fletcher,T.M., Hager,G.L., and Hansen,J.C.Formation of higher-order secondary and tertiary chromatin structures by genomic mouse mammary tumor virus promoters Genes and Dev. 17 1617-1629 2003 Elbi,C., Misteli,T., and Hager,G.L.
Recruitment of the Dioxin Receptor to Active Transcription Sites
Mol. Biol. Cell 13(6) 2001-2015 2002 Fletcher,T.M., Xiao,N., Mautino,G., Baumann,C.T., Warren,B.S., and Hager,G.L.
ATP-dependent mobilization of the glucocorticoid receptor during chromatin remodeling
Mol. Cell. Biol. 22(10) 3255-3263 2002 Hager,G.L., Elbi,C., and Becker,M. Protein dynamics in the nuclear compartment. Curr. Opin. Genet. Dev.12 (2) 137-141 2002 -
Hager, G.L. Understanding nuclear receptor function: From DNA to chromatin to the interphase nucleus.
Prog. Nucleic Acid Res. 66 279-305 2001
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The glucocorticoid receptor: Rapid exchange with regulatory sites in living cells
Science 287(5456) 1262-1265 2000.
Htun, H., Holth, L.T., Walker, D., Davie, J.R., and Hager, G.L. Direct visualization of ligand occupied and unoccupied human estrogen receptor alpha reveals a role for ligand in the nuclear distribution of the receptor. Mol Biol Cell 10 471-486 1999
Fragoso, G., Pennie, W.D., John, S., and Hager, G.L. The position and length of the steroid-dependent hypersensitive region in the mouse mammary tumor virus long terminal repeat are invariant despite multiple nucleosome B frames. Mol. Cell. Biol. 18:3633-3644 1998.
Fragoso G, John S, Roberts MS and Hager GL Nucleosome positioning on the MMTV LTR results from the frequency-biased occupancy of multiple frames. Genes Dev 9: 1933-1947 1995
Roberts MS, Fragoso G, and Hager GL Nucleosomes reconstituted in vitro on mouse mammary tumor virus B region DNA occupy multiple translational and rotational frames. Biochemistry 34: 12470-12481 1995
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