Nitroglycerin - Substance Summary (SID 7847581)
A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
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Medication Information
Nitroglycerin is a 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula isand whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and veins.The MINITRAN (nitroglycerin)  Nitroglycerin, an organic nitrate, is a vasodilator which has effects on both arteries and veins. The chemical name for nitroglycerin is 1,2,3-propanetriol trinitrate (C3H5N3O9). The compound has a molecular weight of 227.09. The chemical Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula is:and whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and veins.NITRO-BID for topical use Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula is:and whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and veins.The NITRO-DUR (nitroglycerin) Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula is:The organic nitrates are vasodilators, active on both arteries and veins. Each Extended-Release Capsule, for oral administration contains 2.5 Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula is:whose empiric formula is C3H5N3O9, and whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and Nitroglycerin is 1,2,3-propanetriol, trinitrate, an organic nitrate whose structural formula is:and whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and veins.The nitroglycerin transdermal Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula is:C3H5N3O9 Mol. weight 227.09The organic nitrates are vasodilators, active on both arteries and veins.Nitroglycerin Injection, USP is a clear, Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula is:and whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and veins.The Nitroglycerin Transdermal Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula is:and whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and veins.The Nitroglycerin Transdermal Nitroglycerin, an organic nitrate, is a vasodilator which has effects on both arteries and veins. The chemical name for nitroglycerin is 1,2,3-propanetriol trinitrate (C3H5N3O9). The compound has a molecular weight of 227.09. The chemical Nitroglycerin is 1,2,3-propanetriol, trinitrate, an organic nitrate whose structural formula isand whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and veins.The Transderm-Nitro Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula iswhose empiric formula is C3H5N3O9, and whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula is:whose molecular formula is C3H5N3O9, and whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and Safety and Toxicology
HSDB - Peer-reviewed summary of toxicity and biomedical effects | NIOSH ICSC - NIOSH International Chemical Safety Cards | NJ-HSFS - New Jersey Material Data Safety Sheets | CCRIS - Carcinogenicity, tumor promotion, tumor inhibition, and mutagenicity tests | EINECS - European Inventory of Existing Commercial Chemical Substances | Haz-Map - Occupational toxicology information | TOXLINE - Citations to the toxicological literature | ClinicalTrials.gov - Registry of federal and private clinical trials |
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 Data Source: 
Depositor: KEGGExternal ID: D00515
 Properties Computed from Structure:
| Molecular Weight | 227.0865 [g/mol] | | Molecular Formula | C3H5N3O9 | | XLogP3 | 1.6 | | H-Bond Donor | 0 | | H-Bond Acceptor | 9 | | Rotatable Bond Count | 5 | | Exact Mass | 227.002579 | | MonoIsotopic Mass | 227.002579 | | Topological Polar Surface Area | 157 | | Heavy Atom Count | 15 | | Formal Charge | 0 | | Complexity | 219 | | Isotope Atom Count | 0 | | Defined Atom StereoCenter Count | 0 | | Undefined Atom StereoCenter Count | 0 | | Defined Bond StereoCenter Count | 0 | | Undefined Bond StereoCenter Count | 0 | | Covalently-Bonded Unit Count | 1 |
Descriptors Computed from Structure:
IUPAC Name: 1,3-dinitrooxypropan-2-yl nitrate
Canonical SMILES: C(C(CO[N+](=O)[O-])O[N+](=O)[O-])O[N+](=O)[O-]
InChI: InChI=1S/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2
InChIKey: SNIOPGDIGTZGOP-UHFFFAOYSA-N
Substance Information:
Depositor-Supplied Comments:
Vasodilator [coronary]
CAS: 55-63-0
DrugBank: DB00727
LigandBox: D00515
Same as: C07455
Therapeutic category: 2149 2171
ATC code: C01DA02 C05AE01
Name previously used: Glyceryl trinitrate
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| Compound ID | 4510 |
| | Molecular Weight | 227.0865 [g/mol] |
| | Molecular Formula | C3H5N3O9 |
| | XLogP3 | 1.6 |
| | H-Bond Donor | 0 |
| | H-Bond Acceptor | 9 |
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