National Cancer Institute (NCI)
A Multicenter Cohort Investigation of Chromosomal Translocations and Hyperdiploidy at Birth and Childhood Leukemia by the International
August 29–30, 2007 • Copenhagen, Denmark
Agenda
Wednesday, August 29
9:00 a.m.
Welcome, Overview of the Workshop Agenda, and Update of Consortium Activities
Terry Dwyer, M.D., M.P.H.
Tasmanian Infant Health Study
Murdoch Childrens Research Institute, Australia
9:30 a.m.
Introductions and Updates from Individual Cohorts
10:45 a.m.
International Incidence Rates and Power Calculations Related to the Exposures and Childhood Leukemia
Martha Linet, M.D., M.P.H
Chief, Radiation Epidemiology Branch
Division of Cancer Epidemiology and Genetics
National Cancer Institute, NIH
11:15 a.m.
Cohort Data Collection: Variables and Timing
Richard Kwok, Ph.D.
Epidemiologist, Environmental Epidemiology and Statistics Program
RTI International
12:00 noon
Policies and Procedures Manual
Carol Kasten, M.D.
Geneticist and Medical Officer
Epidemiology and Genetics Research Program
National Cancer Institute, NIH
Key Current Hypothesis for Collaborative Longitudinal Investigation
1:30 p.m.
Chromosomal Translocations and Hyperdiploidy at Birth
Joseph Wiemels, Ph.D.
Associate Professor, Department of Epidemiology and Biostatistics
University of California, San Francisco
2:00 p.m.
Paternal Age
Jorn Olsen, M.D., Ph.D.
Professor and Chair, Department of Epidemiology
University of California, Los Angeles
2:30 p.m.
Pesticides
Joachim Schüz, Ph.D.
Head, Department of Biostatistics and Epidemiology
Institute of Cancer Epidemiology
Danish Cancer Society, Copenhagen, Denmark
3:15 p.m.
Infection
Eve Roman, Ph.D.
Professor of Epidemiology, Department of Health Sciences
University of York, United Kingdom
3:45 p.m.
Birth Weight for Gestational Age
Joachim Schüz, Ph.D.
4:15 p.m.
Birth Defects and Childhood Cancer
Carol Kasten, M.D.
4:45 p.m.
Wrap-Up of Day 1
Terry Dwyer, M.D., M.P.H.
Thursday, August 30
9:00 a.m.
Recap of Day 1
Terry Dwyer, M.D., M.P.H.
9:15 a.m.
Creation of a Data Dictionary and Core Protocols for Future Analyses
Richard Kwok, Ph.D.
9:45 a.m.
Development of an International Core Study Protocol
Jean Golding, Ph.D., D.Sc.
Avon Longitudinal Study of Parents and Children
Professor, Department of Community Based Medicine
University of Bristol, United Kingdom
10:30 a.m.
Breakout Sessions
Group 1: New Scientific Hypotheses for Cancer Cohorts
Moderator: Joseph Wiemels, Ph.D.
Copy Number Variation and Childhood Cancer
Stefan White
Molecular Development Research Group
Murdoch Childrens Research Institute, Australia
I4C Epigenetics: Global and Gene-Specific Methylation, and Links to Nutritional Factors
Nicholas Wong, Ph.D.
Epigenetics Research Group
Murdoch Childrens Research Institute, Australia
Epimutation and Disease, and Cord Blood Banking on a National Scale
David Martin, M.D.
Children’s Hospital Oakland Research Institute
Translocation Screening in a Centralized Laboratory, Scaling Up for a Large Cohort
Julie Gastier-Foster, Ph.D.
Director, Cytogetics/Molecular Genetics Laboratory
Center for Childhood Cancer, Columbus Children’s Hospital
Group 2: Core Study Protocol and Data Dictionary for Future Analyses
Moderator: Richard Kwok, Ph.D.
Discussion of the Membership Guidelines
Carol Kasten, M.D.
Participating in a Consortia: Experiences from a Cohort
Jean Golding, Ph.D., D.Sc.
Participating in a Consortia: International Perspective
Danuta Krotoski, Ph.D.
Acting Associate Director, Prevention Research and International Programs
National Institute of Child Health and Human Development, NIH
Data Compilation, Next Steps for Future Analyses
Richard Kwok, Ph.D.
1:30 p.m.
Reports from Breakout Sessions
2:30 p.m.
Strategies for Funding
Danuta Krotoski, Ph.D.
Carol Kasten, M.D.
3:30 p.m.
Establishment of Subcommittees
Martha Linet, M.D., M.P.H.
Peter Scheidt, M.D., M.P.H.
National Children’s Study
National Institute of Child Health and Human Development, NIH
4:30 p.m.
Wrap-Up of Meeting and Next Steps
Terry Dwyer, M.D., M.P.H.
