- 39 aomp--yqvdrlbcefghsnuj---- CarB [EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) - 34 aomp--yqvdrlbcefghsnuj---- CarA [EF] COG0505 Carbamoylphosphate synthase small subunit - 40 aom---yqvd-lbce-gh--uj--t- UshA [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases - 27 a-m-kz-q-dr--c-fg--n-j---- - [F] COG1051 ADP-ribose pyrophosphatase - 28 ao-p--yqvdrlbcefghsnuj---- PurH [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) - 12 a-m------d--b-e------j--t- AdeC [F] COG1001 Adenine deaminase - 54 -om-kzy-vdrlbcefgh-nuj--tw Apt [F] COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins - 11 ------y---rl--efg----j--t- Add [F] COG1816 Adenosine deaminase - 11 ----------rlb-efg----j---- Ada [F] COG2169 Adenosine deaminase - 6 --------------efgh-------- CyaA [F] COG3072 Adenylate cyclase - 10 aom-kz------------------t- CyaB [F] COG1437 Adenylate cyclase, class 2 (thermophilic) - 53 ao--k-yqvdrlbcefghsnujxitw Adk [F] COG0563 Adenylate kinase and related kinases - 40 aompk-yqvdrlbcefghsnuj---- PurB [F] COG0015 Adenylosuccinate lyase - 34 aompk-yqvdrlbcefghsnuj---- PurA [F] COG0104 Adenylosuccinate synthase - 8 --mpkz-------------------- AdkA [F] COG2019 Archaeal adenylate kinase - 16 aompkz--v-----e-g--n------ PyrI [F] COG1781 Aspartate carbamoyltransferase regulatory subunit - 33 aompkzyqvdrlbcefg-snuj---- PyrB [F] COG0540 Aspartate carbamoyltransferase, catalytic chain - 43 aompkzyqvdrlbcefghsnujxitw PyrG [F] COG0504 CTP synthase (UTP-ammonia lyase) - 22 -o---zy-vdrlb-e-gh---j--tw Cdd [F] COG0295 Cytidine deaminase - 30 -------qvdrlbcefghsn-jxitw Cmk [F] COG0283 Cytidylate kinase - 11 aompkz------------------t- Cmk [F] COG1102 Cytidylate kinase 2 - 52 aompkzyqvd--bcef-hs-uj---- SsnA [FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases - 35 ------yq-drlbcefghsn-jxi-- - [FJ] COG0590 Cytosine/adenosine deaminases - 14 -----zy-----b-ef-----j---- FUI1 [FH] COG1953 Cytosine/uracil/thiamine/allantoin permeases - 7 ------y--------f----uj--t- NUC1 [F] COG1864 DNA/RNA endonuclease G, NUC1 - 35 aompkz-q--r-bcef-hsnujxi-- Dcd [F] COG0717 Deoxycytidine deaminase - 15 a--pk-y-vd-lb---g-------t- ComEB [F] COG2131 Deoxycytidylate deaminase - 11 ---------d-lb-----------tw - [F] COG1428 Deoxynucleoside kinases - 25 -omp-z-qvdrlbce-gh---j--tw DeoC [F] COG0274 Deoxyribose-phosphate aldolase - 70 aompkzyq-drlbcefghsnujxitw Hit [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - 12 ------y------cefg--nu----- PyrC [F] COG0418 Dihydroorotase - 42 aompkzyqvdrlbcef--s-uj---- PyrC [F] COG0044 Dihydroorotase and related cyclic amidohydrolases - 41 aompkzyqvdrlbcefghsnuj---- PyrD [F] COG0167 Dihydroorotate dehydrogenase - 31 ------yqvdr-bcefghsnujx--- GppA [FP] COG0248 Exopolyphosphatase - 27 -o-p--yqvdrlbcefghsnuj---- PurN [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN - 11 --m-k-----r-bcefgh-------- PurT [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) - 19 -o-----q-dr-bcefghs-uj---- PurU [F] COG0788 Formyltetrahydrofolate hydrolase - 13 ---p--y-v--l----g--n-j---w MIS1 [F] COG2759 Formyltetrahydrofolate synthetase - 50 aompkzyqvdrlbcefghsnuj-it- GuaA [F] COG0518 GMP synthase - Glutamine amidotransferase domain - 36 aompkzyqvdrlbcefghsnuj-it- GuaA [F] COG0519 GMP synthase - PP-ATPase domain - 31 aompk-yqvdrlbcefghsnuj---- PurF [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase - 32 ------yqvdrlbcefghsnujxi-w Gmk [F] COG0194 Guanylate kinase - 24 -------qvdrlb-efghsn-j---w Hpt [F] COG0634 Hypoxanthine-guanine phosphoribosyltransferase - 92 -ompkzyqvdrlbcefghsnuj-it- GuaB [F] COG0516 IMP dehydrogenase/GMP reductase - 17 ------y--dr-b-ef-h--uj---- URH1 [F] COG1957 Inosine-uridine nucleoside N-ribohydrolase - 7 -----------l---f-----j--tw - [F] COG3613 Nucleoside 2-deoxyribosyltransferase - 36 aompkzyq-dr-bcefghsnujxit- Ndk [F] COG0105 Nucleoside diphosphate kinase - 19 -----------lb-e-gh--uj---- NupC [F] COG1972 Nucleoside permease - 37 --------vdrlb-efgh-nuj-itw Pfs [F] COG0775 Nucleoside phosphorylase - 13 ------y---r---efghsn------ Orn [F] COG1949 Oligoribonuclease (3'->5' exoribonuclease) - 38 aompkzyqvdrlbcefghsnuj-i-- PyrE [F] COG0461 Orotate phosphoribosyltransferase - 6 aomp---------------------- - [F] COG0856 Orotate phosphoribosyltransferase homologs - 35 aompkzyqvdrlbcefghsnuj---- PyrF [F] COG0284 Orotidine-5'-phosphate decarboxylase - 15 --m-k---v--l--efgh-------- NrdD [F] COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase - 33 aompk-yqvdrlbcefghsnuj---- PurD [F] COG0151 Phosphoribosylamine-glycine ligase - 31 aompk-yqvdrlbcefghsnuj---- PurM [F] COG0150 Phosphoribosylaminoimidazol (AIR) synthetase - 25 -o-p--yqvdrlbcefghsn-j---- PurK [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) - 34 aompk-yqvdrlbcefghsnujx--- PurC [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase - 31 aompk-yqvdrlbcefghsnuj---- PurE [F] COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase - 20 aompk--qvdrlbc------uj---- PurS [F] COG1828 Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component - 31 aompk-yqvdrlbcefghsnuj---- PurL [F] COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain - 31 aompk-yqvdrlbcefghsnuj---- PurL [F] COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain - 47 aompkzyqvdrlbcefghsnuj--tw PrsA [FE] COG0462 Phosphoribosylpyrophosphate synthetase - 19 -o-pkz-qv-r--c------u-xit- THY1 [F] COG1351 Predicted alternative thymidylate synthase - 10 aompkzy------------------- - [F] COG1936 Predicted nucleotide kinase (related to CMP and AMP kinases) - 12 ---------drlb-e----------w NrdI [F] COG1780 Protein involved in ribonucleotide reduction - 30 aompkzyqv-rlbcef--s--j---- Pnp [F] COG0005 Purine nucleoside phosphorylase - 20 ---pk-y-----b-ef-h-n------ CodB [F] COG1457 Purine-cytosine permease and related proteins - 19 -----z---d-lb-e-gh--uj--tw DeoD [F] COG0813 Purine-nucleoside phosphorylase - 10 ---------drlbc-f-h-------- PyrR [F] COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase - 58 aompkzyqvdrlbcefghsnujxitw NrdA [F] COG0209 Ribonucleotide reductase alpha subunit - 39 -o----yq-drlbcefghsnujxitw NrdF [F] COG0208 Ribonucleotide reductase beta subunit - 18 -o-p----vd-lb-e-gh---j--tw Tdk [F] COG1435 Thymidine kinase - 18 a-m-k---vdrlb-e-g----j---w DeoA [F] COG0213 Thymidine phosphorylase - 46 aompkzyqvdrlbcefghsnujxitw Tmk [F] COG0125 Thymidylate kinase - 26 a-m---y--drlb-efghsn-j---w ThyA [F] COG0207 Thymidylate synthase - 17 -------q-dr-bcefg-snuj---- ThiG [F] COG2022 Uncharacterized enzyme of thiazol biosynthesis - 30 -om-kzyqvdrlbcefgh-nuj--tw Upp [F] COG0035 Uracil phosphoribosyltransferase - 23 -o----y-vd-lbce-gh-----itw Udk [F] COG0572 Uridine kinase - 13 -o---z----rl--e-gh------t- Udp [F] COG2820 Uridine phosphorylase - 42 aompkz-qvdrlbcefghsnujxitw PyrH [F] COG0528 Uridylate kinase - 39 ----k---vd-lb-efgh-n------ UraA [F] COG2233 Xanthine/uracil permeases - 37 aompkzyqvdrlbcefghsnuj-it- - [F] COG0127 Xanthosine triphosphate pyrophosphatase - 17 ---------dr--cefgh---jx--- Dgt [F] COG0232 dGTP triphosphohydrolase - 28 ------yq--rlb-ef-hsnujxit- Dut [F] COG0756 dUTPase