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HRAS Entrez Gene digest
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GeneRIFs
V-Ha-ras Harvey rat sarcoma viral oncogene homolog
Entrez Gene GeneRIFs are recent publications from the PubMed® catalog that contain relevant information about HRAS.
Abramova MV, Pospelova TV, Nikulenkov FP, Hollander CM, Fornace AJ Jr, Pospelov VA. G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of beta-catenin. J Biol Chem. 2006 Jul 28;281(30):21040-51. Epub 2006 May 22.
PubMed citation
Alonio LV, Picconi MA, Dalbert D, Mural J, Bartt O, Bazán G, Dominguez M, Teyssié AR. Ha-ras oncogene mutation associated to progression of papillomavirus induced lesions of uterine cervix. J Clin Virol. 2003 Aug;27(3):263-9.
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Andersson P, Kolaric A, Windahl T, Kirrander P, Söderkvist P, Karlsson MG. PIK3CA, HRAS and KRAS gene mutations in human penile cancer. J Urol. 2008 May;179(5):2030-4. Epub 2008 Mar 19.
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Aoki Y, Niihori T, Kawame H, Kurosawa K, Ohashi H, Tanaka Y, Filocamo M, Kato K, Suzuki Y, Kure S, Matsubara Y. Germline mutations in HRAS proto-oncogene cause Costello syndrome. Nat Genet. 2005 Oct;37(10):1038-40. Epub 2005 Sep 18.
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Auewarakul CU, Lauhakirti D, Tocharoentanaphol C. Frequency of RAS gene mutation and its cooperative genetic events in Southeast Asian adult acute myeloid leukemia. Eur J Haematol. 2006 Jul;77(1):51-6. Epub 2006 Mar 27.
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Bacher U, Haferlach T, Schoch C, Kern W, Schnittger S. Implications of NRAS mutations in AML: a study of 2502 patients. Blood. 2006 May 15;107(10):3847-53. Epub 2006 Jan 24.
PubMed citation
Ballou LM, Chattopadhyay M, Li Y, Scarlata S, Lin RZ. Galphaq binds to p110alpha/p85alpha phosphoinositide 3-kinase and displaces Ras. Biochem J. 2006 Mar 15;394(Pt 3):557-62.
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Berger KL, Barriga F, Lace MJ, Turek LP, Zamba GJ, Domann FE, Lee JH, Klingelhutz AJ. Cervical keratinocytes containing stably replicating extrachromosomal HPV-16 are refractory to transformation by oncogenic H-Ras. Virology. 2006 Dec 5-20;356(1-2):68-78. Epub 2006 Aug 30.
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Bishehsari F, Mahdavinia M, Malekzadeh R, Verginelli F, Catalano T, Sotoudeh M, Bazan V, Agnese V, Esposito DL, De Lellis L, Semeraro D, Colucci G, Hormazdi M, Rakhshani N, Cama A, Piantelli M, Iacobelli S, Russo A, Mariani-Costantini R; Gruppo Oncologico dell'Italia Meridionale. Patterns of K-ras mutation in colorectal carcinomas from Iran and Italy (a Gruppo Oncologico dell'Italia Meridionale study): influence of microsatellite instability status and country of origin. Ann Oncol. 2006 Jun;17 Suppl 7:vii91-6.
PubMed citation
Boettner B, Govek EE, Cross J, Van Aelst L. The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9064-9.
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Boettner B, Govek EE, Cross J, Van Aelst L. The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9064-9.
PubMed citation
Boettner B, Govek EE, Cross J, Van Aelst L. The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9064-9.
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Boissel N, Leroy H, Brethon B, Philippe N, de Botton S, Auvrignon A, Raffoux E, Leblanc T, Thomas X, Hermine O, Quesnel B, Baruchel A, Leverger G, Dombret H, Preudhomme C; Acute Leukemia French Association (ALFA); Leucémies Aiguës Myéloblastiques de l'Enfant (LAME) Cooperative Groups. Incidence and prognostic impact of c-Kit, FLT3, and Ras gene mutations in core binding factor acute myeloid leukemia (CBF-AML). Leukemia. 2006 Jun;20(6):965-70.
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Brandt S, Shafikhani S, Balachandran P, Jin S, Hartig R, König W, Engel J, Backert S. Use of a novel coinfection system reveals a role for Rac1, H-Ras, and CrkII phosphorylation in Helicobacter pylori-induced host cell actin cytoskeletal rearrangements. FEMS Immunol Med Microbiol. 2007 Jul;50(2):190-205. Epub 2007 Apr 11.
PubMed citation
Calistri D, Rengucci C, Seymour I, Lattuneddu A, Polifemo AM, Monti F, Saragoni L, Amadori D. Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression. J Cell Physiol. 2005 Aug;204(2):484-8.
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Castro P, Soares P, Gusmão L, Seruca R, Sobrinho-Simões M. H-RAS 81 polymorphism is significantly associated with aneuploidy in follicular tumors of the thyroid. Oncogene. 2006 Aug 3;25(33):4620-7. Epub 2006 Mar 13.
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Cavaco BM, Batista PF, Martins C, Banito A, do Rosário F, Limbert E, Sobrinho LG, Leite V. Familial non-medullary thyroid carcinoma (FNMTC): analysis of fPTC/PRN, NMTC1, MNG1 and TCO susceptibility loci and identification of somatic BRAF and RAS mutations. Endocr Relat Cancer. 2008 Mar;15(1):207-15.
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Chen CY, Lin LI, Tang JL, Tsay W, Chang HH, Yeh YC, Huang CF, Chiou RJ, Yao M, Ko BS, Chen YC, Lin KH, Lin DT, Tien HF. Acquisition of JAK2, PTPN11, and RAS mutations during disease progression in primary myelodysplastic syndrome. Leukemia. 2006 Jun;20(6):1155-8. No abstract available.
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Chen Y, Takita J, Hiwatari M, Igarashi T, Hanada R, Kikuchi A, Hongo T, Taki T, Ogasawara M, Shimada A, Hayashi Y. Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies. Genes Chromosomes Cancer. 2006 Jun;45(6):583-91.
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Chizhikov VV, Chikina SIu, Tatosian AG, Chuchalin AG, Zborovskaia IB. [Development of chronic obstructive pulmonary disease correlates with mini- and microsatellite locus instability] Genetika. 2003 May;39(5):694-701. Russian.
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Chu S, Li L, Singh H, Bhatia R. BCR-tyrosine 177 plays an essential role in Ras and Akt activation and in human hematopoietic progenitor transformation in chronic myelogenous leukemia. Cancer Res. 2007 Jul 15;67(14):7045-53.
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Córdova-Alarcón E, Centeno F, Reyes-Esparza J, García-Carrancá A, Garrido E. Effects of HRAS oncogene on cell cycle progression in a cervical cancer-derived cell line. Arch Med Res. 2005 Jul-Aug;36(4):311-6.
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Crowder C, Kopantzev E, Williams K, Lengel C, Miki T, Rudikoff S. An unusual H-Ras mutant isolated from a human multiple myeloma line leads to transformation and factor-independent cell growth. Oncogene. 2003 Feb 6;22(5):649-59.
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Cyniak-Magierska A, Brzeziańska E, Januszkiewicz-Caulier J, Jarzab B, Lewiński A. Prevalence of RAS point mutations in papillary thyroid carcinoma; a novel mutation at codon 31 of K-RAS. Exp Clin Endocrinol Diabetes. 2007 Oct;115(9):594-9.
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Czyzyk J, Chen HC, Bottomly K, Flavell RA. p21 Ras/impedes mitogenic signal propagation regulates cytokine production and migration in CD4 T cells. J Biol Chem. 2008 Aug 22;283(34):23004-15. Epub 2008 Jun 24.
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Dai Y, Khanna P, Chen S, Pei XY, Dent P, Grant S. Statins synergistically potentiate 7-hydroxystaurosporine (UCN-01) lethality in human leukemia and myeloma cells by disrupting Ras farnesylation and activation. Blood. 2007 May 15;109(10):4415-23. Epub 2007 Jan 30.
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Datta D, Flaxenburg JA, Laxmanan S, Geehan C, Grimm M, Waaga-Gasser AM, Briscoe DM, Pal S. Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer. Cancer Res. 2006 Oct 1;66(19):9509-18.
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Datta S, Hoenerhoff MJ, Bommi P, Sainger R, Guo WJ, Dimri M, Band H, Band V, Green JE, Dimri GP. Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways. Cancer Res. 2007 Nov 1;67(21):10286-95.
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de Gorter DJ, Vos JC, Pals ST, Spaargaren M. The B cell antigen receptor controls AP-1 and NFAT activity through Ras-mediated activation of Ral. J Immunol. 2007 Feb 1;178(3):1405-14.
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Denayer E, Parret A, Chmara M, Schubbert S, Vogels A, Devriendt K, Frijns JP, Rybin V, de Ravel TJ, Shannon K, Cools J, Scheffzek K, Legius E. Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation. Hum Mutat. 2008 Feb;29(2):232-9.
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Dougherty MK, Müller J, Ritt DA, Zhou M, Zhou XZ, Copeland TD, Conrads TP, Veenstra TD, Lu KP, Morrison DK. Regulation of Raf-1 by direct feedback phosphorylation. Mol Cell. 2005 Jan 21;17(2):215-24.
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Dow LE, Elsum IA, King CL, Kinross KM, Richardson HE, Humbert PO. Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling. Oncogene. 2008 Oct 9;27(46):5988-6001. Epub 2008 Jul 21.
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Drosopoulos KG, Roberts ML, Cermak L, Sasazuki T, Shirasawa S, Andera L, Pintzas A. Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway. J Biol Chem. 2005 Jun 17;280(24):22856-67. Epub 2005 Mar 8.
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Eastin WC, Mennear JH, Tennant RW, Stoll RE, Branstetter DG, Bucher JR, McCullough B, Binder RL, Spalding JW, Mahler JF. Tg.AC genetically altered mouse: assay working group overview of available data. Toxicol Pathol. 2001;29 Suppl:60-80.
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Ehmann F, Horn S, Garcia-Palma L, Wegner W, Fiedler W, Giehl K, Mayr GW, Jücker M. Detection of N-RAS and K-RAS in their active GTP-bound form in acute myeloid leukemia without activating RAS mutations. Leuk Lymphoma. 2006 Jul;47(7):1387-91.
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Elowe S, Holland SJ, Kulkarni S, Pawson T. Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction. Mol Cell Biol. 2001 Nov;21(21):7429-41.
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Etienne-Grimaldi MC, Formento JL, Francoual M, François E, Formento P, Renée N, Laurent-Puig P, Chazal M, Benchimol D, Delpero JR, Letoublon C, Pezet D, Seitz JF, Milano G. K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy. Clin Cancer Res. 2008 Aug 1;14(15):4830-5.
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Fernandez-Garcia B, Vaqué JP, Herreros-Villanueva M, Marques-Garcia F, Castrillo F, Fernandez-Medarde A, León J, Marín MC. p73 cooperates with Ras in the activation of MAP kinase signaling cascade. Cell Death Differ. 2007 Feb;14(2):254-65. Epub 2006 Apr 28.
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Figueroa C, Taylor J, Vojtek AB. Prenylated Rab acceptor protein is a receptor for prenylated small GTPases. J Biol Chem. 2001 Jul 27;276(30):28219-25. Epub 2001 May 2.
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Fischer A, Hekman M, Kuhlmann J, Rubio I, Wiese S, Rapp UR. B- and C-RAF display essential differences in their binding to Ras: the isotype-specific N terminus of B-RAF facilitates Ras binding. J Biol Chem. 2007 Sep 7;282(36):26503-16. Epub 2007 Jul 16.
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Ford B, Hornak V, Kleinman H, Nassar N. Structure of a transient intermediate for GTP hydrolysis by ras. Structure. 2006 Mar;14(3):427-36.
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Freeman DJ, Juan T, Reiner M, Hecht JR, Meropol NJ, Berlin J, Mitchell E, Sarosi I, Radinsky R, Amado RG. Association of K-ras mutational status and clinical outcomes in patients with metastatic colorectal cancer receiving panitumumab alone. Clin Colorectal Cancer. 2008 May;7(3):184-90.
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Fujiwara K, Enomoto T, Fujita M, Kanda T, Fujii S, Ito K, Wakasa K, Ishiko O, Ueda M, Yamaguchi S, Kimura T, Umesaki N. Alterations of the K-ras and p53 genes in Tamoxifen-associated endometrial carcinoma. Oncol Rep. 2008 May;19(5):1293-8.
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Galaktionov K, Jessus C, Beach D. Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation. Genes Dev. 1995 May 1;9(9):1046-58.
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Gao J, Huang HY, Pak J, Cheng J, Zhang ZT, Shapiro E, Pellicer A, Sun TT, Wu XR. p53 deficiency provokes urothelial proliferation and synergizes with activated Ha-ras in promoting urothelial tumorigenesis. Oncogene. 2004 Jan 22;23(3):687-96.
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Gohlke H, Kuhn LA, Case DA. Change in protein flexibility upon complex formation: analysis of Ras-Raf using molecular dynamics and a molecular framework approach. Proteins. 2004 Aug 1;56(2):322-37.
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Goldberg M, Wei M, Yuan L, Murty VV, Tycko B. Biallelic expression of HRAS and MUCDHL in human and mouse. Hum Genet. 2003 Apr;112(4):334-42. Epub 2003 Feb 14.
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Gomez GA, Daniotti JL. Electrical properties of plasma membrane modulate subcellular distribution of K-Ras. FEBS J. 2007 May;274(9):2210-28. Epub 2007 Mar 27.
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Goutas N, Vlachodimitropoulos D, Bouka M, Lazaris AC, Nasioulas G, Gazouli M. BRAF and K-RAS mutation in a Greek papillary and medullary thyroid carcinoma cohort. Anticancer Res. 2008 Jan-Feb;28(1A):305-8.
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Grigorenko BL, Nemukhin AV, Shadrina MS, Topol IA, Burt SK. Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations. Proteins. 2007 Feb 1;66(2):456-66.
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Gripp KW, Innes AM, Axelrad ME, Gillan TL, Parboosingh JS, Davies C, Leonard NJ, Lapointe M, Doyle D, Catalano S, Nicholson L, Stabley DL, Sol-Church K. Costello syndrome associated with novel germline HRAS mutations: an attenuated phenotype? Am J Med Genet A. 2008 Mar 15;146A(6):683-90.
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Gripp KW, Stabley DL, Nicholson L, Hoffman JD, Sol-Church K. Somatic mosaicism for an HRAS mutation causes Costello syndrome. Am J Med Genet A. 2006 Oct 15;140(20):2163-9.
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Guha A, Lau N, Huvar I, Gutmann D, Provias J, Pawson T, Boss G. Ras-GTP levels are elevated in human NF1 peripheral nerve tumors. Oncogene. 1996 Feb 1;12(3):507-13.
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Guha A, Lau N, Huvar I, Gutmann D, Provias J, Pawson T, Boss G. Ras-GTP levels are elevated in human NF1 peripheral nerve tumors. Oncogene. 1996 Feb 1;12(3):507-13.
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Gulbins E, Schlottmann K, Brenner B, Lang F, Coggeshall KM. Molecular analysis of Ras activation by tyrosine phosphorylated Vav. Biochem Biophys Res Commun. 1995 Dec 26;217(3):876-85.
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Güldenhaupt J, Adigüzel Y, Kuhlmann J, Waldmann H, Kötting C, Gerwert K. Secondary structure of lipidated Ras bound to a lipid bilayer. FEBS J. 2008 Dec;275(23):5910-8.
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Gureasko J, Galush WJ, Boykevisch S, Sondermann H, Bar-Sagi D, Groves JT, Kuriyan J. Membrane-dependent signal integration by the Ras activator Son of sevenless. Nat Struct Mol Biol. 2008 May;15(5):452-61. Epub 2008 May 4. Erratum in: Nat Struct Mol Biol.2008 Jun;15(6): 651.
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Hallberg B, Rayter SI, Downward J. Interaction of Ras and Raf in intact mammalian cells upon extracellular stimulation. J Biol Chem. 1994 Feb 11;269(6):3913-6.
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Han L, Wong D, Dhaka A, Afar D, White M, Xie W, Herschman H, Witte O, Colicelli J. Protein binding and signaling properties of RIN1 suggest a unique effector function. Proc Natl Acad Sci U S A. 1997 May 13;94(10):4954-9.
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Hanna AN, Chan EY, Xu J, Stone JC, Brindley DN. A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase. J Biol Chem. 1999 Apr 30;274(18):12722-9.
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Hanna AN, Chan EY, Xu J, Stone JC, Brindley DN. A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase. J Biol Chem. 1999 Apr 30;274(18):12722-9.
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Hanzal-Bayer M, Renault L, Roversi P, Wittinghofer A, Hillig RC. The complex of Arl2-GTP and PDE delta: from structure to function. EMBO J. 2002 May 1;21(9):2095-106.
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Hanzal-Bayer M, Renault L, Roversi P, Wittinghofer A, Hillig RC. The complex of Arl2-GTP and PDE delta: from structure to function. EMBO J. 2002 May 1;21(9):2095-106.
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Harada N, Oshima H, Katoh M, Tamai Y, Oshima M, Taketo MM. Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations. Cancer Res. 2004 Jan 1;64(1):48-54.
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Harms KL, Chen X. p19ras brings a new twist to the regulation of p73 by Mdm2. Sci STKE. 2006 May 30;2006(337):pe24. Review.
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Haworth RS, Dashnyam S, Avkiran M. Ras triggers acidosis-induced activation of the extracellular-signal-regulated kinase pathway in cardiac myocytes. Biochem J. 2006 Nov 1;399(3):493-501.
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Heo J, Campbell SL. Superoxide anion radical modulates the activity of Ras and Ras-related GTPases by a radical-based mechanism similar to that of nitric oxide. J Biol Chem. 2005 Apr 1;280(13):12438-45. Epub 2005 Jan 31.
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Hernández-Muñoz I, Benet M, Calero M, Jiménez M, Díaz R, Pellicer A. rgr oncogene: activation by elimination of translational controls and mislocalization. Cancer Res. 2003 Jul 15;63(14):4188-95.
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Hernández-Muñoz I, Benet M, Calero M, Jiménez M, Díaz R, Pellicer A. rgr oncogene: activation by elimination of translational controls and mislocalization. Cancer Res. 2003 Jul 15;63(14):4188-95.
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Hiraoka S, Kato J, Tatsukawa M, Harada K, Fujita H, Morikawa T, Shiraha H, Shiratori Y. Laterally spreading type of colorectal adenoma exhibits a unique methylation phenotype and K-ras mutations. Gastroenterology. 2006 Aug;131(2):379-89.
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Hiwasa T, Kasama M, Nakadai T, Sawada T, Sakiyama S. Loss of Raf-1-binding activity of v-Ha-Ras by the deletion of amino acid residues 64-72 and 143-151. Cell Signal. 1996 Aug;8(5):393-6.
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Hofer F, Fields S, Schneider C, Martin GS. Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator. Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):11089-93.
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Hokaiwado N, Asamoto M, Cho YM, Tsuda H, Shirai T. Lack of effect of human c-Ha-ras proto-oncogene overexpression on prostate carcinogenesis in probasin/SV40 T antigen transgenic rats. Cancer Sci. 2003 Dec;94(12):1042-5.
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Houlston RS, Tomlinson IP. Polymorphisms and colorectal tumor risk. Gastroenterology. 2001 Aug;121(2):282-301.
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Huang YZ, Zang M, Xiong WC, Luo Z, Mei L. Erbin suppresses the MAP kinase pathway. J Biol Chem. 2003 Jan 10;278(2):1108-14. Epub 2002 Oct 11.
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Huang YZ, Zang M, Xiong WC, Luo Z, Mei L. Erbin suppresses the MAP kinase pathway. J Biol Chem. 2003 Jan 10;278(2):1108-14. Epub 2002 Oct 11.
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Husi H, Ward MA, Choudhary JS, Blackstock WP, Grant SG. Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Nat Neurosci. 2000 Jul;3(7):661-9.
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Indsto JO, Kumar S, Wang L, Crotty KA, Arbuckle SM, Mann GJ. Low prevalence of RAS-RAF-activating mutations in Spitz melanocytic nevi compared with other melanocytic lesions. J Cutan Pathol. 2007 Jun;34(6):448-55.
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Janzarik WG, Kratz CP, Loges NT, Olbrich H, Klein C, Schäfer T, Scheurlen W, Roggendorf W, Weiller C, Niemeyer C, Korinthenberg R, Pfister S, Omran H. Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma. Neuropediatrics. 2007 Apr;38(2):61-3.
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Jałoszyński P, Masutani C, Hanaoka F, Perez AB, Nishimura S. 8-Hydroxyguanine in a mutational hotspot of the c-Ha-ras gene causes misreplication, 'action-at-a-distance' mutagenesis and inhibition of replication. Nucleic Acids Res. 2003 Nov 1;31(21):6085-95.
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Jelinek T, Catling AD, Reuter CW, Moodie SA, Wolfman A, Weber MJ. RAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2. Mol Cell Biol. 1994 Dec;14(12):8212-8.
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Jelinek T, Catling AD, Reuter CW, Moodie SA, Wolfman A, Weber MJ. RAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2. Mol Cell Biol. 1994 Dec;14(12):8212-8.
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Jeon SH, Oh SW, Kang UG, Ahn YM, Bae CD, Park JB, Kim YS. Electroconvulsive shock increases the phosphorylation of Pyk2 in the rat hippocampus. Biochem Biophys Res Commun. 2001 Apr 13;282(4):1026-30.
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Jin M, Matsumoto S, Dewa Y, Nishimura J, Saekusa Y, Hasumi K, Mitsumori K. Extremely weak tumor-promoting effect of troglitazone on splenic hemangiosarcomas in rasH2 mice induced by urethane. Arch Toxicol. 2008 Oct;82(10):771-7. Epub 2008 May 9.
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Johmura Y, Suzuki M, Osada S, Nishizuka M, Imagawa M. FAD24, a regulator of adipogenesis and DNA replication, inhibits H-RAS-mediated transformation by repressing NF-kappaB activity. Biochem Biophys Res Commun. 2008 May 2;369(2):464-70. Epub 2008 Feb 20.
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Karbowniczek M, Robertson GP, Henske EP. Rheb inhibits C-raf activity and B-raf/C-raf heterodimerization. J Biol Chem. 2006 Sep 1;281(35):25447-56. Epub 2006 Jun 27.
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Kaul A, Overmeyer JH, Maltese WA. Activated Ras induces cytoplasmic vacuolation and non-apoptotic death in glioblastoma cells via novel effector pathways. Cell Signal. 2007 May;19(5):1034-43. Epub 2006 Nov 28.
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Khwaja A, Dockrell ME, Hendry BM, Sharpe CC. Prenylation is not necessary for endogenous Ras activation in non-malignant cells. J Cell Biochem. 2006 Feb 1;97(2):412-22.
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Kim JW, Kim WH, Jeong MH, Jang SM, Song KH, Park SI, Song PI, Kang KH, Choi KH. p19(ras) amplifies p73beta-induced apoptosis through mitochondrial pathway. Biochem Biophys Res Commun. 2008 Aug 15;373(1):146-50. Epub 2008 Jun 12.
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Kocher HM, Senkus R, Moorhead J, Al-Nawab M, Patel AG, Benjamin IS, Hendry BM. Expression of Ras GTPase isoforms in normal and diseased pancreas. Pancreatology. 2005;5(2-3):205-14. Epub 2005 Apr 22.
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Kolokoltsova OA, Domina AM, Kolokoltsov AA, Davey RA, Weaver SC, Watowich SJ. Alphavirus production is inhibited in neurofibromin 1-deficient cells through activated RAS signalling. Virology. 2008 Jul 20;377(1):133-42. Epub 2008 May 15.
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Kosztin I, Bruinsma R, O'Lague P, Schulten K. Mechanical force generation by G proteins. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3575-80.
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Kratz CP, Steinemann D, Niemeyer CM, Schlegelberger B, Koscielniak E, Kontny U, Zenker M. Uniparental disomy at chromosome 11p15.5 followed by HRAS mutations in embryonal rhabdomyosarcoma: lessons from Costello syndrome. Hum Mol Genet. 2007 Feb 15;16(4):374-9. Epub 2006 Dec 12. Erratum in: Hum Mol Genet. 2007 Nov 15;16(22):2781.
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Kristensen AT, Wiig JN, Larsen SG, Giercksky KE, Ekstrøm PO. Molecular detection (k-ras) of exfoliated tumour cells in the pelvis is a prognostic factor after resection of rectal cancer? BMC Cancer. 2008 Jul 27;8:213.
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Kuiperij HB, de Rooij J, Rehmann H, van Triest M, Wittinghofer A, Bos JL, Zwartkruis FJ. Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2. Biochim Biophys Acta. 2003 Feb 17;1593(2-3):141-9.
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Kuppens S, Hellings M, Jordens J, Verheyden S, Engelborghs Y. Conformational states of the switch I region of Ha-ras-p21 in hinge residue mutants studied by fluorescence lifetime and fluorescence anisotropy measurements. Protein Sci. 2003 May;12(5):930-8.
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Lafuente EM, van Puijenbroek AA, Krause M, Carman CV, Freeman GJ, Berezovskaya A, Constantine E, Springer TA, Gertler FB, Boussiotis VA. RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion. Dev Cell. 2004 Oct;7(4):585-95.
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Lambert JM, Lambert QT, Reuther GW, Malliri A, Siderovski DP, Sondek J, Collard JG, Der CJ. Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism. Nat Cell Biol. 2002 Aug;4(8):621-5.
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Lambert JM, Lambert QT, Reuther GW, Malliri A, Siderovski DP, Sondek J, Collard JG, Der CJ. Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism. Nat Cell Biol. 2002 Aug;4(8):621-5.
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Lee JS, Gil JE, Kim JH, Kim TK, Jin X, Oh SY, Sohn YW, Jeon HM, Park HJ, Park JW, Shin YJ, Chung YG, Lee JB, You S, Kim H. Brain cancer stem-like cell genesis from p53-deficient mouse astrocytes by oncogenic Ras. Biochem Biophys Res Commun. 2008 Jan 18;365(3):496-502. Epub 2007 Nov 20.
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Published: February 6, 2009