AOD Thesaurus.  Annotated Hierarchy.  chemical substances by structure.  ZJ - ZL4.6
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ZJcarboxylic acids and derivatives   d-out   qh
NT+ZK lipids, fatty acids, fats and oils    qh   ah
BT+ZDe organic compounds    qh   ah

ZJ2ecarboxylic acid   qh
ZJ2.2e.  acyclic carboxylic acid   qh
NT+ZJ2.6.4e acetic acid    qh   ah
ZJ2.4e.  methylphenydate   qh
BT+YP10.8.10 agents for cocaine-concurrent mental disorders    qh   ah
ZJ2.6e.  saturated carboxylic acid   qh
ST carboxylic acid ester
ZJ2.6.2e.  .  formic acid   qh
ST methanoic acid
ZJ2.6.2.2e.  .  .  formate   qh
ZJ2.6.2.2.2e.  .  .  .  ethyl formate   qh
ST formic acid ethyl ester
RT+BX2.2.4e congener    qh   ah
ZJ2.6.4e.  .  acetic acid   qh
ST ethanoic acid
BT+ZJ2.2e acyclic carboxylic acid    qh   ah
+ZK4.8e volatile fatty acid    qh   ah
RT+ZN2.20.2.2e acetamide    qh   ah
ZJ2.6.4.2e.  .  .  acetate   qh
RT EB10.12.8e ethanol metabolite    qh   ah
ZJ2.6.4.2.2e.  .  .  .  acetic acid ester   qh
ZJ2.6.4.2.2.2e.  .  .  .  .  ethyl acetate   qh
RT+BX2.2.4e congener    qh   ah
ZJ2.6.4.4e.  .  .  trichloroacetic acid   qh
ZJ2.6.6e.  .  propionic acid   qh
ST propanoic acid
BT+ZK4.8e volatile fatty acid    qh   ah
ZJ2.6.6.2e.  .  .  propionate   qh
ZJ2.6.6.2.2e.  .  .  .  propoxyphene   qh
ST dextropropoxyphene
BT+BT6.8.6 schedule IV opioids    qh   ah
+YW4.2e narcotic analgesics    qh   ah
+ZQ18e synthetic opioids    qh   ah
ZJ2.6.8e.  .  ibuprofen   qh
BT+YP4.2e anti-alcohol-intoxication agents    qh   ah
ZJ2.6.10e.  .  butyric acid   qh
ST butanoic acid
BT+ZK4.8e volatile fatty acid    qh   ah
ZJ2.6.10.2e.  .  .  butyrate   qh
ZJ2.6.10.2.2e.  .  .  .  aminobutyric acid   qh
BT+YV4 neuroregulators    qh   ah
+ZO2e amino acids    qh   ah
ZJ2.6.10.2.2.2e.  .  .  .  .  GABA   qh
ST gamma-aminobutyric acid
BT+YJ2e neurotransmitters    qh   ah
RT+YK6.8e GABA receptors    qh   ah
+ZT6.4.2e benzodiazepines    qh   ah
ZJ2.6.10.2.2.2.2e.  .  .  .  .  .  baclofen   qh
ZJ2.6.10.2.2.4e.  .  .  .  .  endothelin   qh
HN Introduced 1995.
BT+YMe other biological factors    qh   ah
ZJ2.6.10.2.4e.  .  .  .  hydroxybutyrate   qh
BT+ZJ2.10.4e hydroxy acids    qh   ah
ZJ2.6.10.2.4.2e.  .  .  .  .  sodium oxybate   qh
BT+YR4e anesthetics    qh   ah
+YW4.4e general anesthetics    qh   ah
ZJ2.6.10.4e.  .  .  carbamates   qh
ZJ2.6.10.4.2e.  .  .  .  meprobamate   qh
SN One of the (antianxiety) tranquilizers used for muscle relaxation and sedation. Meprobamate is less potent than the minor tranquilizers derived from benzodiazepine such as chlordiazepoxide hydrochloride (Librium) and diazepam (Valium). Manufactured as Miltown and Equanil.
BT+BT6.8.2 schedule IV CNS depressants    qh   ah
+YT6.2 central muscle relaxants    qh   ah
+YW4.8e sedative-hypnotics    qh   ah
+YW4.8.6e antianxiety tranquilizers    qh   ah
ZJ2.6.10.4.4e.  .  .  .  thiocarbamates   qh
ZJ2.6.10.4.4.2e.  .  .  .  .  diethylthiocarbamate   qh
ZJ2.6.10.4.4.2.2e.  .  .  .  .  .  disulfiram   qh
SN The prototypic alcohol-sensitizing drug prescribed to assist in maintaining abstinence from alcohol. Disulfiram inhibits aldehyde dehydrogenase activity and, in the presence of alcohol, causes accumulation of acetaldehyde and an aversive facial flushing reaction accompanied by nausea, dizziness, and palpitations. These effects are sometimes termed "the Antabuse reaction".
ST Antabuse
NT HK2.12.2.2 disulfiram therapy    qh   ah
BT+YD8.2 ADH antagonists    qh   ah
+YP4.2e anti-alcohol-intoxication agents    qh   ah
+YP4.8.8e alcohol deterrents    qh   ah
RT+ZG2.4e acetaldehyde    qh   ah
ZJ2.6.10.4.4.4e.  .  .  .  .  dimethyldithiocarbamate   qh
ZJ2.6.10.4.4.4.2e.  .  .  .  .  .  thiram   qh
BT+YQ4.2 local anti-infective agents    qh   ah
+YQ4.8 antifungal agents    qh   ah
+YX10.4.4 industrial fungicides    qh   ah
ZJ2.6.10.4.6e.  .  .  .  urethane   qh
BT+YD8.2 ADH antagonists    qh   ah
+YQ6 antineoplastic agents    qh   ah
ZJ2.6.12e.  .  valeric acid   qh
ST pentanoic acid
BT+ZK4.8e volatile fatty acid    qh   ah
ZJ2.6.12.2e.  .  .  valerate   qh
ZJ2.6.12.2.2e.  .  .  .  valproate   qh
BT+YW4.6e anticonvulsants    qh   ah
ZJ2.6.14e.  .  caproic acid   qh
ST hexanoic acid
BT+ZK4.8e volatile fatty acid    qh   ah
ZJ2.6.14.2e.  .  .  penicillic acid   qh
BT+YX2.12 mycotoxins    qh   ah
+YX4e carcinogens    qh   ah
ZJ2.6.14.4e.  .  .  caproate   qh
ZJ2.6.20e.  .  capric acid   qh
ST decanoic acid
BT+ZK4e fatty acids    qh   ah
ZJ2.6.22e.  .  lauric acid   qh
ST dodecanoic acid
BT+ZK4e fatty acids    qh   ah
ZJ2.6.24e.  .  myristic acid   qh
ST tetradecanoic acid
BT+ZK4e fatty acids    qh   ah
ZJ2.6.26e.  .  palmitic acid   qh
ST hexadecanoic acid
BT+ZK4e fatty acids    qh   ah
ZJ2.6.26.2e.  .  .  palmitate   qh
ZJ2.6.28e.  .  stearic acid   qh
ST octadecanoic acid
BT+ZK4e fatty acids    qh   ah
ZJ2.6.28.2e.  .  .  stearate   qh
ZJ2.6.30e.  .  eicosanoic acid   qh
ST arachidic acid
BT+ZK4e fatty acids    qh   ah
ZJ2.8e.  unsaturated carboxylic acid   qh
NT+ZK4.4e unsaturated fatty acids    qh   ah
ZJ2.8.2.  .  monounsaturated carboxylic acid   qh
HN Introduced 1995.
ZJ2.8.4.  .  polyunsaturated carboxylic acid   qh
HN Introduced 1995.
NT+ZK4.4.2.2e arachidonic acid    qh   ah
 ZK4.4.4e linoleic acid    qh   ah
 ZK4.4.6.2e linolenic acid    qh   ah
ZJ2.10e.  substituted carboxylic acid   qh
ZJ2.10.2e.  .  halogen substituted acid   qh
ZJ2.10.4e.  .  hydroxy acids   qh
NT+ZG8.4e sugar acids    qh   ah
+ZJ2.6.10.2.4e hydroxybutyrate    qh   ah
+ZJ2.10.10.2.4e hydroxybenzoic acid    qh   ah
RT+ZO2e amino acids    qh   ah
ZJ2.10.4.2e.  .  .  gamma-hydroxybutyric acid   qh
BT+YP4.8.2.6 GABA receptor agonist anti-alcohol-craving agents    qh   ah
ZJ2.10.4.4e.  .  .  benzilate   qh
ZJ2.10.4.4.2e.  .  .  .  quinuclidinyl benzilate   qh
BT+YV8e parasympatholytics    qh   ah
+ZT12.2e quinuclidine    qh   ah
ZJ2.10.4.6e.  .  .  glycolate   qh
ST glycolic acid
ZJ2.10.4.8e.  .  .  methylphenidate   qh
SN A CNS stimulant similar to amphetamines that is often prescribed for the treatment of hyperkinesis in children and for weight control in adults. Manufactured as Ritalin.
ST methylphenidate hydrochloride
Ritalin
BT+BT6.4.6 schedule II CNS stimulants    qh   ah
+YP10.8.10.6 agents for cocaine-related cognitive impairment    qh   ah
ZJ2.10.4.10e.  .  .  phosphoenolpyruvate   qh
BT+EB4.2 high-energy compound    qh   ah
RT YC10.10.6 phosphoenolpyruvate carboxykinase    qh   ah
ZJ2.10.6e.  .  keto acids   qh
NT+ZG4e ketones    qh   ah
 ZJ2.12.2.2.2e oxaloacetate    qh   ah
+ZN2.20.6.2e hippurates    qh   ah
ZJ2.10.6.2e.  .  .  acetoacetic acid   qh
ZJ2.10.6.2.2e.  .  .  .  acetoacetate   qh
ZJ2.10.6.4e.  .  .  levulinic acid   qh
ZJ2.10.6.4.2e.  .  .  .  aminolevulinic acid   qh
RT YC10.14.2 aminolevulinic acid dehydratase    qh   ah
ZJ2.10.6.6e.  .  .  pyruvate   qh
RT YC8.6 pyruvate carboxylase    qh   ah
 YC10.10.10 pyruvate decarboxylase    qh   ah
 YC14.12.2 pyruvate oxidase    qh   ah
 YC16.14.6.16e pyruvate kinase    qh   ah
ZJ2.10.8e.  .  organic sulfur acids   qh
ST sulfur acids (organic)
BT+ZR4e organic sulfur compounds    qh   ah
ZJ2.10.8.2e.  .  .  sulfonic acid   qh
ZJ2.10.8.2.2e.  .  .  .  alkyl sulfonate   qh
ZJ2.10.8.2.2.2e.  .  .  .  .  taurine   qh
NT ZV10.2.4e taurocholic acid    qh   ah
BT+BJ2.2e amphetamines    qh   ah
+YJ2e neurotransmitters    qh   ah
ZJ2.10.8.2.2.2.2e.  .  .  .  .  .  calcium acetylhomotaurinate   qh
HN Introduced 1995.
ST Acamprosate
BT+YP4.8.2.6 GABA receptor agonist anti-alcohol-craving agents    qh   ah
ZJ2.10.8.2.2.2.4e.  .  .  .  .  .  bis acetyl homotaurine   qh
BT+YP4.8.2.6 GABA receptor agonist anti-alcohol-craving agents    qh   ah
ZJ2.10.10e.  .  aromatic carboxylic acid   qh
ST carbocyclic acid
ZJ2.10.10.2e.  .  .  benzoic acid   qh
NT+ZN2.20.6e benzamides    qh   ah
ZJ2.10.10.2.2e.  .  .  .  aminobenzoic acid   qh
BT+YB12e vitamin B complex    qh   ah
ZJ2.10.10.2.2.2e.  .  .  .  .  4-aminobenzoic acid   qh
ZJ2.10.10.2.2.2.2e.  .  .  .  .  .  procainamide   qh
BT+YT8.2 antiarrhythmia agents    qh   ah
ZJ2.10.10.2.2.2.4e.  .  .  .  .  .  procaine   qh
BT+YR4.2e local anesthetics    qh   ah
ZJ2.10.10.2.4e.  .  .  .  hydroxybenzoic acid   qh
BT+ZF4e phenols    qh   ah
+ZJ2.10.4e hydroxy acids    qh   ah
ZJ2.10.10.2.4.2e.  .  .  .  .  salicylic acid   qh
ZJ2.10.10.2.4.2.2e.  .  .  .  .  .  acetylsalicylic acid   qh
ST aspirin
BT+YT14.6 platelet aggregation inhibitors    qh   ah
ZJ2.10.10.2.4.2.4e.  .  .  .  .  .  salicylate   qh
BT+YQ2.2 nonsteroidal anti-inflammatory drugs    qh   ah
+YR2.2 nonnarcotic analgesics    qh   ah
ZJ2.10.10.2.4.2.4.2e.  .  .  .  .  .  .  sodium salicylate   qh
ZJ2.10.10.2.6e.  .  .  .  lactate   qh
RT+YC14.2.4.6e lactate dehydrogenases    qh   ah
ZJ2.10.10.4e.  .  .  cyclohexanecarboxylic acid   qh
ZJ2.10.10.4.2e.  .  .  .  tilidine   qh
BT+BT6.2.8.2 schedule I opiates    qh   ah
+YR2e analgesics    qh   ah
ZJ2.10.10.6e.  .  .  phthalic acid   qh
ZJ2.10.10.6.2e.  .  .  .  phthalimide   qh
ZJ2.10.10.6.2.2e.  .  .  .  .  thalidomide   qh
BT+YQ4.6.2 leprostatic agents    qh   ah
+YW4.8.4e nonbarbiturate sedative-hypnotics    qh   ah
+YX6e teratogens    qh   ah
+ZT4.20.8e piperidone    qh   ah
ZJ2.10.10.6.4e.  .  .  .  phenylacetates   qh
HN Introduced 2000.
ZJ2.10.10.6.4.2e.  .  .  .  .  dihydroxyphenylacetic acid   qh
HN Introduced 2000.
ST DOPAC
homoprotocatechuic acid
ZJ2.12e.  polycarboxylic acid   qh
ZJ2.12.2e.  .  dicarboxylic acid   qh
ZJ2.12.2.2e.  .  .  oxalate   qh
ZJ2.12.2.2.2e.  .  .  .  oxaloacetate   qh
BT+ZJ2.10.6e keto acids    qh   ah
ZJ2.12.2.4e.  .  .  succinate   qh
NT+ZN2.16.2.10.2e succinylcholine    qh   ah
 ZN6.2e succinimide    qh   ah
RT YC14.32 succinate dehydrogenase    qh   ah
ZJ2.12.4e.  .  tricarboxylic acid   qh
RT EB4.6 tricarboxylic acid cycle    qh   ah

ZJ4carboxylic acid derivatives   qh
ZJ4.2e.  esters   qh
RT+BX2.2.4e congener    qh   ah
 CM30.2 esterification    qh   ah
ZJ4.8e.  nitrogen-containing carboxylic acid derivative   qh
NT+ZN2.20.2e amides    qh   ah
ZJ4.8.2e.  .  nitriles   qh
BT+ZMe organic nitrogen compounds    qh   ah
RT+ZC12.6e cyanide    qh   ah
ZJ4.8.4e.  .  hydrazides   qh
RT ZF6.4e hydrazine    qh   ah
ZJ4.8.6e.  .  azide   qh

ZKlipids, fatty acids, fats and oils   d-out   qh
SN Lipids contain fats and fatty acids.
NT EB14e lipid metabolism    qh   ah
+ZO6.8.18e lipoproteins    qh   ah
 ZO6.8.28e proteolipid    qh   ah
+ZV12.4e sterols    qh   ah
BT+ZJ carboxylic acids and derivatives    qh   ah
RT+GH14.4e nutritional deficiency    qh   ah
+YAe nutrients    qh   ah
ZK2e.  lipids   qh
NT+GR6e lipid metabolism disorder    qh   ah
ZK2.2e.  .  glycolipids   qh
ZK2.2.2e.  .  .  ganglioside   qh
ZK2.2.4e.  .  .  phosphoinositide   qh
RT YC4.6.4.6.2 phospholipase C    qh   ah
+ZF2.12.4.2e inositol phosphate    qh   ah
ZK2.4e.  .  phospholipids   qh
ZK2.4.2e.  .  .  glycerophosphate   qh
ZK2.4.2.2e.  .  .  .  phosphatidic acid   qh
ZK2.4.2.2.2e.  .  .  .  .  phosphatidylcholine   qh
ST lecithin
phosphatidyl choline
ZK2.4.2.2.4e.  .  .  .  .  phosphatidylethanol   qh
HN Introduced 2000.
BT+HB4.6.2.2e AODR biochemical markers    qh   ah
ZK2.4.2.2.4.2e.  .  .  .  .  .  phosphatidylethanolamine   qh
ST PE
phosphatidyl ethanolamine
BT+ZN2e amines    qh   ah
ZK2.4.2.2.6e.  .  .  .  .  phosphatidylinositol   qh
ST inositol phospholipid
phosphatidyl inositol
RT+ZF2.12.4.2e inositol phosphate    qh   ah
ZK2.4.2.2.6.2e.  .  .  .  .  .  phosphatidylinositol phosphate   qh
ST phosphatidylinositol biphosphate
phosphatidylinositol bisphosphate
ZK2.4.2.2.8e.  .  .  .  .  phosphatidylserine   qh
ST phosphatidyl serine
ZK2.4.2.4e.  .  .  .  phospholipid ether   qh
BT+ZF6e ethers    qh   ah
ZK2.4.2.4.2e.  .  .  .  .  plasmalogen   qh
ZK2.4.2.4.4e.  .  .  .  .  platelet-activating factor   qh
BT+YE10e cytokines    qh   ah
+ZO6.4.10.6.4e blood coagulation factors    qh   ah
ZK2.4.4e.  .  .  liposomes   qh
HN Introduced 2000.
RT XA2.12.10 membrane layer    qh   ah
ZK2.6e.  .  sphingolipids   qh
ZK2.6.2e.  .  .  ceramide   qh
ZK2.6.2.2e.  .  .  .  sphingomyelin   qh
ZK4e.  fatty acids   qh
NT ZJ2.6.20e capric acid    qh   ah
 ZJ2.6.22e lauric acid    qh   ah
 ZJ2.6.24e myristic acid    qh   ah
+ZJ2.6.26e palmitic acid    qh   ah
+ZJ2.6.28e stearic acid    qh   ah
 ZJ2.6.30e eicosanoic acid    qh   ah
RT YC14.10.2 fatty acid desaturases    qh   ah
ZK4.2e.  .  fatty acid ethyl esters   qh
HN Introduced 2000.
ST FAEE
ZK4.4e.  .  unsaturated fatty acids   qh
BT+ZJ2.8e unsaturated carboxylic acid    qh   ah
ZK4.4.2e.  .  .  eicosanoids   qh
SN Class of substances that exhibit a wide range of biologic activity.
NT+ZK4.4.8e prostaglandins    qh   ah
 ZK4.6e thromboxane    qh   ah
ZK4.4.2.2e.  .  .  .  arachidonic acid   qh
BT+ZJ2.8.4 polyunsaturated carboxylic acid    qh   ah
ZK4.4.2.2.2e.  .  .  .  .  leukotrienes   qh
ZK4.4.4e.  .  .  linoleic acid   qh
BT+ZJ2.8.4 polyunsaturated carboxylic acid    qh   ah
ZK4.4.6e.  .  .  omega-3 fatty acid   qh
ZK4.4.6.2e.  .  .  .  linolenic acid   qh
BT+ZJ2.8.4 polyunsaturated carboxylic acid    qh   ah
ZK4.4.8e.  .  .  prostaglandins   qh
NT YM14.2 prostaglandin antagonists    qh   ah
BT+YM14 slow-reacting substances    qh   ah
+ZK4.4.2e eicosanoids    qh   ah
RT XU2 diffuse endocrine system    qh   ah
 YC12.2e prostaglandin synthase    qh   ah
ZK4.4.8.2e.  .  .  .  prostacyclin   qh
HN Introduced 1995.
ST epoprostenol
PGI2
PGX
prostaglandin I2
prostaglandin X
BT+YT14.6 platelet aggregation inhibitors    qh   ah
ZK4.4.8.4e.  .  .  .  prostaglandin endoperoxide   qh
ZK4.4.8.6e.  .  .  .  synthetic prostaglandin   qh
ZK4.4.8.6.2e.  .  .  .  .  misoprostol   qh
HN Introduced 1995.
BT+YS reproductive control agents    qh   ah
+YT10.8 antiulcer agents    qh   ah
ZK4.6e.  .  thromboxane   qh
BT+YM14 slow-reacting substances    qh   ah
+ZK4.4.2e eicosanoids    qh   ah
RT YC6.6 thromboxane synthetase    qh   ah
ZK4.8e.  .  volatile fatty acid   qh
NT+ZJ2.6.4e acetic acid    qh   ah
+ZJ2.6.6e propionic acid    qh   ah
+ZJ2.6.10e butyric acid    qh   ah
+ZJ2.6.12e valeric acid    qh   ah
+ZJ2.6.14e caproic acid    qh   ah
ZK4.10e.  .  prostanoic acid   qh
ZK4.12e.  .  sodium morrhuate   qh
ZK6e.  glycerides   qh
ZK6.2e.  .  diglycerides   qh
ST diacylglycerol
BT+YM2.4e intracellular messengers    qh   ah
RT+YM2.2e second messengers    qh   ah
 ZO6.6.12.2.6e G q/11 alpha    qh   ah
ZK6.4e.  .  triglycerides   qh
ZK6.4.2e.  .  .  triolein   qh
BT+ZK8.4e unsaturated fat    qh   ah
ZK8e.  fats   qh
RT+ZK10e oils    qh   ah
ZK8.2e.  .  dietary fats   qh
ZK8.4e.  .  unsaturated fat   qh
NT ZK6.4.2e triolein    qh   ah
ZK10e.  oils   qh
RT+ZK8e fats    qh   ah
ZK10.2.  .  plant oil   qh
HN Introduced 1995.
ZK10.2.2.  .  .  croton oil   qh
HN Introduced 1995.
NT+ZU10.4.2e phorbol ester    qh   ah
BT+YX4e carcinogens    qh   ah


ZLorganic halogen compounds   d-out   qh
BT+ZDe organic compounds    qh   ah

ZL2ehalogenated hydrocarbons   qh
BT+ZEe hydrocarbons    qh   ah
ZL2.2e.  fluorocarbons   qh
SN A large group of chlorinated or fluorinated hydrocarbons now used chiefly as refrigerants. Prior to 1978, they were widely used as aerosol propellants in household products and were subject to abuse because of their intoxicating (anesthetic) effects when inhaled. Fluorocarbons and chlorofluorocarbons were banned from use in household consumer products on March 16, 1978, by the U.S. Environmental Protection Agency under the Toxic Substance Control Act of 1976. The aerosol propellants currently used by industry are pentane, pentene, and other such hydrocarbons. Because of their flammability, they are believed to pose more of a safety than health threat to society.
ST fluorinated hydrocarbons
BT+BG4 aerosol propellant of abuse    qh   ah
ZL2.2.2e.  .  freon   qh
RT+BGe volatile inhalant    qh   ah
ZL2.4e.  halothane   qh
RT+YW4.8e sedative-hypnotics    qh   ah
ZL2.6e.  chlorinated hydrocarbons   qh
ZL2.6.2e.  .  carbon tetrachloride   qh
SN A highly toxic, chlorinated hydrocarbon liquid that was widely used at one time as a solvent in cleaning fluids and, when inhaled, produced intoxication. Toxic reactions include headache, confusion, depression, fatigue, nausea, vomiting, and death. Both the vapor and the liquid irritate skin and eyes.
BT+BG2 solvent of abuse    qh   ah
ZL2.6.4e.  .  chloroform   qh
SN A vaporous anesthetic depressant similar to ether that is capable of producing an alcohol-like intoxication when inhaled. Never very popular, chloroform is known to be more frequently fatal than any of the other anesthetics or alcohol. It also is used as a solvent.
ST trichloromethane
BT+YR4e anesthetics    qh   ah
+YW4.4e general anesthetics    qh   ah
RT+BGe volatile inhalant    qh   ah
ZL2.6.6e.  .  trichloroethane   qh
ZL2.6.8e.  .  trichloroethylene   qh
HN Introduced 1995.
ST ethinyl trichloride
BT+YR4e anesthetics    qh   ah
ZL2.8e.  mustard compounds   qh

ZL4ehalogenated steroids   qh
BT+ZVe steroids    qh   ah
ZL4.4e.  fluorinated steroids   qh
NT YH4.6.2.2e dexamethasone    qh   ah


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