Bibliographic Citation
| Document | For copies of Journal Articles, please contact the Publisher or your local public or university library and refer to the information in the Resource Relation field. For copies of other documents, please see the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or Document Availability. |
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| Title | Solute flux coupling in a homopore membrane |
| Creator/Author | Van Bruggen, J.T. (Univ. of Oregon, Portland) ; Boyett, J.D. ; Van Bueren, A.L. ; Galey, W.R. |
| Publication Date | 1974 Jan 01 |
| OSTI Identifier | OSTI ID: 6682410 |
| Other Number(s) | CODEN: JGPLA |
| Resource Type | Journal Article |
| Resource Relation | J. Gen. Physiol. ; Vol/Issue: 63 |
| Subject | 551000 -- Physiological Systems ;550200 -- Biochemistry; ;MEMBRANE TRANSPORT; BIOCHEMICAL REACTION KINETICS;DRAG;FILMS;FLUID FLOW;FLUID MECHANICS;MEMBRANES;PERMEABILITY;PHYSIOLOGY;POLYCARBONATES;POROUS MATERIALS;SOLUTIONS |
| Related Subject | CARBON COMPOUNDS;CARBONATES;DISPERSIONS;KINETICS;MATERIALS;MECHANICS;MIXTURES;OXYGEN COMPOUNDS;REACTION KINETICS |
| Description/Abstract | Our previous studies on solute drag on frog skin and synthetic heteropore membranes have been extended to a synthetic homopore membrane.^The 150-A radius pores of this membrane are formed by irradiation and etching of polycarbonate films.^The membrane is 6-..mu..m thick and it has 6 x 10/sup 8/ pores cm/sup -2/.^In this study, sucrose has been used as the driver solute with bulk flow blocked by hydrostatic pressure.^As before on heteroporous membranes, the transmembrane asymmetry of tracer solute is dependent on the concentration of the driver solute.^Tracer sucrose shows no solute drag while maltotriose shows appreciable solute drag at 1.5 M sucrose.^With tracer inulin and dextran, solute drag is detectable at 0.5 M sucrose.^These results are in keeping with the previous findings on heteropore membranes.^Transmembrane solute drag is the result of kinetic and frictional interaction of the driver and tracer solutes as the driver flows down its concentration gradient.^The magnitude of the tracer flux asymmetry is also dependent on the size of the transmembrane pores. |
| Country of Publication | United States |
| Language | English |
| Format | Pages: 639-656 |
| System Entry Date | 2001 May 13 |
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