ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES VACCINES FOR CHILDREN PROGRAM VACCINES TO PREVENT POLIOMYELITIS The purpose of this resolution is to revise the previous resolution to incorporate current recommendations on the use of polio vaccines. VFC resolution 10/98-2 is hereby repealed and replaced by the following: Eligible Groups Recommended Pneumococcal Conjugate Vaccine Schedule Age Page 1 of 3 Recommended Dosage Intervals Recommended Dosages Inactivated Polio Vaccine Contraindications and Precautions The following conditions are contraindications to the administration of IPV vaccine: 1. Allergy to vaccine components Persons who have had anaphylactic reactions or systemically administered streptomycin, neomycin or polymyxin B should not receive IPV. 2. Moderate or severe illnesses with or without fever The following conditions are contraindications to the administration of inactivated polio vaccine (IPV): 1. Pregnancy It is prudent on theoretical grounds to avoid vaccinating pregnant women with IPV vaccine. However, if immediate protection against poliomyelitis is needed, IPV may be administered. Oral Polio Vaccine Contraindications and Precautions The following conditions are contraindications to the administration of OPV vaccine: 1. In persons who have experienced an anaphylactic reaction to previous dose of OPV. 2. Moderate or severe illnesses with or without fever 3. Altered immune status Altered immune status due to: malignant condition (blood dyscrasia, leukemia, lymphoma, or other neoplasms affecting the bone marrow of lymphatic systems); primary or acquired immune deficiency, including acquired immunodeficiencies, hypgammaglobulinemia, and dysgammaglobulinemia; family history of congenital or hereditary immunodeficiency, unless immune competenceof possible vaccine recipient is demonstrated; and individuals receiving immunosuppressive therapy. 4. Persons with HIV infection Although OPV has not been harmful when administered to asymptomatic HIV-infected children, IPV is the vaccine of choice for a child who is known to be HIV infected. Testing for HIV-infection of asymptomatic children is not necessary before decisions regarding immunization with polio vaccine are made. Page 2 of 3 5. Presence of Immunodeficient household contacts. OPV should not be used for immunization of household contacts of immunodeficient patients; IPV is recommended. 6. Steroid therapy Receiving doses of systemic prednisone or equivalent at a dose of > 2 mg/kg of body weight per day or 20 mg/day. The following condition is a precaution to the administration of OPV vaccine: 1. Pregnancy It is prudent on theoretical grounds to avoid vaccinating pregnant women with IPV vaccine. However, if immediate protection against poliomyelitis is needed, IPV may be administered. Adopted and Effective: February 17, 2000 http://www.cdc.gov/vaccines/programs/vfc/downloads/resolutions/203polio.txt Page 3 of 3 Resolution No. 2/00-2