Jauregui Rueda H, Balbaryski J, del Castillo M, Monticelli A; International Conference on AIDS.
Int Conf AIDS. 1994 Aug 7-12; 10: 163 (abstract no. PB0079).
L.I.C. Laboratory Buenos Aires, Argentina.
OBJECTIVE: 1) To evaluate four immunological markers in HIV infected patients classificated according to the CDC classification, April 1992. 2) To determine if some of the studied markers be of more predictive value in the progression of the infection. 3) The relationship between markers and mortality. METHODS: The records of patients with HIV infection attending the L.I.C. LABORATORY, Buenos Aires, Argentina were reviewed from January'92 to December'93. It was studied CD4+ linphocytes count, B2 microglobuline, Agp24 and the level of IgA in 34 patients (31 male, 3 female; average age: 30 years old). The patients were classificated according to the CDC classification. RESULTS: TABULAR DATA, SEE ABSTRACT VOLUME. DISCUSSION AND CONCLUSIONS: 1 GROUP 1 (44%) did not modify his stage A1A2, presenting normal values of CD4+ abs, B2microglobuline, IgA level, and Agp24 not reactive. GROUP 2 (12%) made a progress of the infection-disease from A1A2-B1B2-C1C2 with a continuous decrease of CD4+ count, increase of B2microglobuline and IgA level, and discontinuous reactivity of Agp24. GROUP 3 (44%) made a progress of infection-disease to stage C3 where the CD4+ count decreased below 50 cell/mm3, a major increasement of B2microglobuline and IgA level, and reactive Agp24. 2) Linphocytes CD4+ count showed the best correlation with the progression of the infection. 3) In GROUP 3 the 27% of the patients died, not presenting any correlation between the parameter and the mortality date.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Anti-HIV Agents
- Antigens, CD4
- Argentina
- Biological Markers
- CD4 Lymphocyte Count
- Centers for Disease Control and Prevention (U.S.)
- Communicable Diseases
- Disease Progression
- Evolution
- Female
- HIV
- HIV Infections
- HIV Seropositivity
- Humans
- Male
- United States
- genetics
- immunology
Other ID:
UI: 102208344
From Meeting Abstracts