Human Genome Epidemiology (HuGE) Articles
April 21, 2005
Volume 14, No. 16
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These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.
![Gene Variant Frequency](../../file/images/scilit_head_gene.gif)
CYP3A5 genetic polymorphisms in different ethnic populations Roy JN, et al.
Drug Metab Dispos 2005 Apr
hOGG1 SER326CYS genetic polymorphism in a Turkish population
Karahalil1 B & Kocabas NA
Arch Toxicol 2005 Apr
![Infectious and Parasitic Diseases](../../file/images/scilit_head_infect.gif)
Frequency of interleukin-4 (IL-4) -589 gene polymorphism and vaginal concentrations of IL-4, nitric oxide, and mannose-binding lectin in women with recurrent vulvovaginal candidiasis Babula O, et al.
Clin Infect Dis 2005 May;40(9):1258-62
Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C patients Adinolfi LE, et al.
Hepatology 2005 Apr;41(5):995-1003
![Neoplasms](../../file/images/scilit_head_neoplasm.gif)
Cyp17, urinary sex steroid levels and breast cancer risk in postmenopausal women Onland-Moret NC , et al.
Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):815-20
The race associated allele of semaphorin 3B (SEMA3B) T415I and its role in lung cancer in African-Americans and Latino-Americans Marsit CJ, et al.
Carcinogenesis 2005 Apr
Accuracy of MSI testing in predicting germline mutations of MSH2 and MLH1: a case study in Bayesian meta-analysis of diagnostic tests without a gold standard Chen S, et al.
Biostatistics 2005 Apr
The C/C-13910 genotype of adult-type hypolactasia is associated with an increased risk of colorectal cancer in the Finnish population Rasinpera H, et al.
Gut 2005 May;54(5):643-7
Influences of apolipoprotein E polymorphism on the risk for breast cancer and HER2/neu status in Taiwan Chang NW, et al.
Breast Cancer Res Treat 2005 Apr;90(3):257-61
No association of the matrix metalloproteinase 1 promoter polymorphism with susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma in northern China Jin X, et al.
World J Gastroenterol 2005 Apr;11(16):2385-9
Diets, polymorphisms of methylenetetrahydrofolate reductase, and the susceptibility of colon cancer and rectal cancer Jiang Q, et al.
Cancer Detect Prev 2005;29(2):146-54
Genetic polymorphisms of ataxia telangiectasia mutated and breast cancer risk Lee KM, et al.
Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):821-5
APC Asp1822Val and Gly2502Ser Polymorphisms and Risk of Colorectal Cancer and Adenoma Tranah GJ, et al.
Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):863-70
The T393C Polymorphism of the G{alpha}s Gene (GNAS1) Is a Novel Prognostic Marker in Bladder Cancer Frey UH, et al.
Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):871-7
Polymorphisms in XPD Exons 10 and 23 and Bladder Cancer Risk Schabath MB , et al.
Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):878-84
No Evidence for BRAF as a Melanoma/Nevus Susceptibility Gene Jackson S, et al.
Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):913-8
The MTHFR 1298A>C Polymorphism and Genomic DNA Methylation in Human Lymphocytes Friso S, et al.
Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):938-43
Association of Susceptibility Alleles in ELAC2/HPC2, RNASEL/HPC1, and MSR1 with Prostate Cancer Severity in European American and African American Men Rennert H, et al.
Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):949-57
Genotyping of patients with sporadic and radiation-associated meningiomas Sadetzki S, et al.
Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):969-76
The e211 g>a androgen receptor polymorphism is associated with a decreased risk of metastatic prostate cancer and androgenetic alopecia Hayes VM, et al.
Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):993-6
Genetic variants in the vitamin d receptor gene and prostate cancer risk Hayes VM, et al.
Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):997-9
Polymorphisms in genes involved in xenobiotic metabolism and lung cancer risk under the age of 60 years A pooled study of lung cancer patients in Denmark and Norway Skuladottir H, et al.
Lung Cancer 2005 May;48(2):187-99
Analysis of the dinucleotide repeat polymorphism in the epidermal growth factor receptor (EGFR) gene in head and neck cancer patients Etienne-Grimaldi MC, et al.
Ann Oncol 2005 Apr
Polymorphisms in GLTSCR1 and ERCC2 are associated with the development of oligodendrogliomas Yang P, et al.
Cancer 2005 Apr
![Endocrine, Nutritional and Metabolic Diseases](../../file/images/scilit_head_endocrine.gif)
Association of nucleotide variations in the apolipoprotein B48 receptor gene (APOB48R) with hypercholesterolemia Fujita Y, et al.
J Hum Genet 2005 Apr
Molecular genetics and phenotypic characteristics of MODY caused by hepatocyte nuclear factor 4alpha mutations in a large European collection Pearson ER, et al.
Diabetologia 2005 Apr
Association between plasma activities of semicarbazide-sensitive amine oxidase and angiotensin-converting enzyme in patients with type 1 diabetes mellitus Boomsma F, et al.
Diabetologia 2005 Apr
The Lewis blood group-a new genetic marker of obesity Hein HO, et al.
Int J Obes Relat Metab Disord 2005 May;29(5):540-2
Analysis of mannose-binding lectin 2 (MBL2) genotype and the serum protein levels in the Korean population Lee SG, et al.
Mol Immunol 2005 May;42(8):969-77
Cystic fibrosis carriers have higher neonatal immunoreactive trypsinogen values than non-carriers Castellani C, et al.
Am J Med Genet A 2005 Apr:9999
Analysis of sequence variability in the CART gene in relation to obesity in a Caucasian population Guerardel A, et al.
BMC Genet 2005 Apr;6(1):19
The relationship of molecular genetic to clinical diagnosis of familial hypercholesterolemia in a Danish population Damgaard D, et al.
Atherosclerosis 2005 May;180(1):155-60
Population spectrum of ACADM genotypes correlated to biochemical phenotypes in newborn screening for medium-chain acyl-CoA dehydrogenase deficiency Maier EM, et al.
Hum Mutat 2005 Apr;25(5):443-52
No association between insulin gene variation and adult metabolic phenotypes in a large Finnish birth cohort Bennett A, et al.
Diabetologia 2005 Apr
Variation in ITGB3 has sex-specific associations with plasma lipoprotein(a) and whole blood serotonin levels in a population-based sample Weiss LA, et al.
Hum Genet 2005 Apr
Haplotype construction of the FRDA gene and evaluation of its role in type II diabetes Holmkvist J, et al.
Eur J Hum Genet 2005 Apr
A study of the Hexose-6-Phosphate Dehydrogenase Gene R453Q and 11{beta}-Hydroxysteroid Dehydrogenase Type 1 Gene 83557insA Polymorphisms in the Polycystic Ovary Syndrome Millan JL, et al.
J Clin Endocrinol Metab 2005 Apr
Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity Biason-Lauber A, et al.
Diabetologia 2005 Apr
![Mental Disorders](../../file/images/scilit_head_mental.gif)
Association between the 5-HT6 receptor C267T polymorphism and response to antidepressant treatment in major depressive disorder Lee SH, et al.
Psychiatry Clin Neurosci 2005 Apr;59(2):140-5
Association study of 12 polymorphisms spanning the dopamine D(2) receptor gene and clozapine treatment response in two treatment refractory/intolerant populations Hwang R, et al.
Psychopharmacology (Berl) 2005 Apr
Antipsychotics and dopamine transporter gene polymorphisms in delirium patients Kim JY, et al.
Psychiatry Clin Neurosci 2005 Apr;59(2):183-8
The SNAP-25 gene may be associated with clinical response and weight gain in antipsychotic treatment of schizophrenia Muller DJ, et al.
Neurosci Lett 2005 May;379(2):81-9
Association Between Alcoholism and gamma-Amino Butyric Acid alpha2 Receptor Subtype in a Russian Population Lappalainen J, et al.
Alcohol Clin Exp Res 2005 Apr;29(4):493-8
Lack of association of the COMT (Val(158/108) Met) gene and schizophrenia: a meta-analysis of case-control studies Munafo MR, et al.
Mol Psychiatry 2005 Apr
Population-based and family-based studies on the serotonin transporter gene polymorphisms and bipolar disorder: a systematic review and meta-analysis Cho HJ, et al.
Mol Psychiatry 2005 Apr
Role of the serotonin transporter gene and family function in adolescent alcohol consumption Nilsson KW, et al.
Alcohol Clin Exp Res 2005 Apr;29(4):564-70
Dopamine Transporter Genotype and Methylphenidate Dose Response in Children with ADHD Stein MA, et al.
Neuropsychopharmacology 2005 Apr
Severity of Guillain-Barre syndrome is associated with Fcgamma Receptor III polymorphisms van Sorge NM, et al.
J Neuroimmunol 2005 May;162(1-2):157-64
Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration Zareparsi S, et al.
Hum Mol Genet 2005 Apr
Homocysteine and related genetic polymorphisms in Down's syndrome IQ Gueant JL, et al.
J Neurol Neurosurg Psychiatry 2005 May;76(5):706-9
MMP-9 microsatellite polymorphism and susceptibility to exudative form of age-related macular degeneration Fiotti N, et al.
Genet Med 2005 Apr;7(4):272-7
Early-onset Parkinson's disease in a Chinese population: (99m)Tc-TRODAT-1 SPECT, Parkin gene analysis and clinical study Shyu WC, et al.
Parkinsonism Relat Disord 2005 May;11(3):173-80
GJB2 (connexin 26) mutations are not a major cause of hearing loss in the Indonesian population Snoeckx RL, et al.
Am J Med Genet A 2005 Apr
Heat Shock Protein 70 and Tumor Necrosis Factor Alpha in Taiwanese Patients with Dementia Fung HC, et al.
Dement Geriatr Cogn Disord 2005 Apr;20(1):1-7
Evaluating Associations between 5-HTTLPR Polymorphism and Alzheimer's Disease for Korean Patients Ha TM, et al.
Dement Geriatr Cogn Disord 2005 Apr;20(1):31-4
Association between Angiotensin-Converting Enzyme Gene Polymorphism and Alzheimer's Disease in a Chinese Population Zhang JW, et al.
Dement Geriatr Cogn Disord 2005 Apr;20(1):52-6
Glutathione-S-transferase-1 and interleukin-1beta gene polymorphisms in Japanese patients with Parkinson's disease Nishimura M, et al.
Mov Disord 2005 Apr
Association of C825T polymorphism of G protein beta3 subunit with the autonomic nervous system in young healthy Japanese individuals Matsunaga T, et al.
Am J Hypertens 2005 Apr;18(4):523-9
APOE influences vasospasm and cognition of noncomatose patients with subarachnoid hemorrhage Lanterna LA, et al.
Neurology 2005 Apr;64(7):1238-44
Genetic predictors of coronary heart disease risk factors in premenopausal African-American women Giger JN, et al.
Ethn Dis 2005 Spring;15(2):221-32
Detection of 677CT/1298AC "double variant" chromosomes: Implications for interpretation of MTHFR genotyping results Brown NM , et al.
Genet Med 2005 Apr;7(4):278-82
Association of a polymorphism of the transforming growth factor-{beta}1 gene with cerebral amyloid angiopathy Hamaguchi T, et al.
J Neurol Neurosurg Psychiatry 2005 May;76(5):696-9
Endothelial nitric oxide synthase intron 4 polymorphism is a marker for coronary artery disease in African-American and Caucasian men Rao S, et al.
Ethn Dis 2005 Spring;15(2):191-7
Matrix metalloproteinase3 and 9 gene promoter polymorphisms: joint action of two loci as a risk factor for coronary artery complicated plaques Pollanen PJ, et al.
Atherosclerosis 2005 May;180(1):73-8
Association of interleukin-6 gene G-174C polymorphism and plasma plasminogen activator inhibitor-1 level in Chinese patients with and without hypertension Jeng JR, et al.
Am J Hypertens 2005 Apr;18(4):517-22
The hemochromatosis C282Y allele: a risk factor for hepatic veno-occlusive disease after hematopoietic stem cell transplantation Kallianpur AR , et al.
Bone Marrow Transplant 2005 Apr
Apolipoprotein A-I/C-III/A-IV SstI and apolipoprotein B XbaI polymorphisms and their association with carotid artery intima-media thickness in the Finnish population The Cardiovascular Risk in Young Finns Study Islam MS, et al.
Atherosclerosis 2005 May;180(1):79-86
Effect of low-density lipoprotein receptor mutation on lipoproteins and cardiovascular disease risk: a parent-offspring study Koeijvoets KC, et al.
Atherosclerosis 2005 May;180(1):93-9
Variants of the natural resistance-associated macrophage protein 1 gene (NRAMP1) are associated with severe forms of pulmonary tuberculosis Zhang W, et al.
Clin Infect Dis 2005 May;40(9):1232-6
![Diseases of the Digestive System](../../file/images/scilit_head_digest.gif)
Might there be a link between mannose-binding lectin polymorphism and dental caries? Pehlivan S, et al.
Mol Immunol 2005 May;42(9):1125-7
![Diseases of the Genitourinary System](../../file/images/scilit_head_genit.gif)
Angiotensin-I converting enzyme insertion/deletion polymorphism and its association with diabetic nephropathy: a meta-analysis of studies reported between 1994 and 2004 and comprising 14,727 subjects Ng DP, et al.
Diabetologia 2005 Apr
![Diseases of the Musculoskeletal System and Connective Tissue](../../file/images/scilit_head_muscle.gif)
The extent of ossification of posterior longitudinal ligament of the spine associated with nucleotide pyrophosphatase gene and leptin receptor gene polymorphisms Tahara M, et al.
Spine 2005 Apr;30(8):877-80
Association between single nucleotide polymorphisms of estrogen receptor {alpha} gene and efficacy of HRT on bone mineral density in post-menopausal Japanese women Yahata T, et al.
Hum Reprod 2005 Apr
The relation of the Xbal and Pvull polymorphisms of the estrogen receptor gene and the CAG repeat polymorphism of the androgen receptor gene to peak bone mass and bone turnover rate among young healthy men Valimaki VV, et al.
Osteoporos Int 2005 Apr
Functional Analysis of the Single Nucleotide Polymorphism (787T>C) in the Tissue-Nonspecific Alkaline Phosphatase Gene Associated With BMD Goseki-Sone M, et al.
J Bone Miner Res 2005 May;20(5):773-82
![Congenital Anomalies](../../file/images/scilit_head_congent.gif)
Fragile X syndrome carrier screening in the prenatal genetic counseling setting Cronister A, et al.
Genet Med 2005 Apr;7(4):246-50
![Certain Conditions Originating in the Perinatal Period](../../file/images/scilit_head_perinatal.gif)
Thrombophilic Polymorphisms and Intrauterine Growth Restriction Infante-Rivard C, et al.
Epidemiology 2005 May;16(3):281-7
![Symptoms, Signs, and Ill-defined Conditions](../../file/images/scilit_head_symptom.gif)
Influence of CYP2C9 polymorphisms, demographic factors and concomitant drug therapy on warfarin metabolism and maintenance dose Herman D, et al.
Pharmacogenomics J 2005 Apr
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