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Last Modified: 2/13/2009     First Published: 11/25/2005  
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Past Highlights
Phase III Randomized Study of Carboplatin and Paclitaxel Versus Carboplatin, Paclitaxel, and Concurrent Bevacizumab With Versus Without Extended Bevacizumab in Patients With Stage III or IV Ovarian Epithelial, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Alternate Title
Basic Trial Information
Objectives
Entry Criteria
Expected Enrollment
Outcomes
Outline
Trial Contact Information
Related Information
Registry Information

Alternate Title

Carboplatin and Paclitaxel With or Without Bevacizumab in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Basic Trial Information

Phase
 Type
 Status
 Age
 Sponsor
 Protocol IDs

Phase III
Treatment
Active
18 and over
NCI
GOG-0218
NCT00262847

Special Category: NCI Web site featured trial, CTSU trial

Objectives

Primary

  1. Compare the overall survival of patients with stage III or stage IV ovarian epithelial, primary peritoneal cancer, or fallopian tube cancer treated with carboplatin and paclitaxel vs carboplatin, paclitaxel, and concurrent bevacizumab with vs without extended bevacizumab.

Secondary

  1. Compare the duration of progression-free survival of patients treated with these regimens.
  2. Compare the incidence of severe toxicity of these regimens in these patients.
  3. Compare the quality of life of patients treated with these regimens.

Tertiary

  1. Determine the relationship between angiogenic markers and clinical outcome (tumor response, progression-free survival, and overall survival) in patients treated with these regimens.
  2. Determine the predictive value of a set of genes whose expression correlates with survival of these patients.

Entry Criteria

Disease Characteristics:

  • Histologically confirmed ovarian epithelial, primary peritoneal*, or fallopian tube cancer
    • Stage III with any gross (macroscopic or palpable) residual disease OR stage IV disease

     [Note: May have co-existing fallopian tube carcinoma in-situ so long as the primary origin of invasive tumor is ovarian or peritoneal.]



  • The following histologic epithelial cell types are allowed provided the histologic features of the tumor are compatible with a primary müllerian epithelial adenocarcinoma:
    • Serous adenocarcinoma
    • Endometrioid adenocarcinoma
    • Mucinous adenocarcinoma
    • Undifferentiated carcinoma
    • Clear cell adenocarcinoma
    • Mixed epithelial carcinoma
    • Transitional cell carcinoma
    • Malignant Brenner tumor
    • Adenocarcinoma not otherwise specified


  • No borderline ovarian epithelial tumor (formerly "tumors of low malignant potential")
    • Prior diagnosis of a borderline tumor that was surgically resected and an unrelated, new, invasive ovarian epithelial or primary peritoneal cancer that subsequently develops is allowed provided there was no prior chemotherapy for any ovarian tumor


  • No recurrent invasive ovarian epithelial cancer treated with surgery only (e.g., stage IA or IB low-grade epithelial ovarian or fallopian tube cancer)


  • No synchronous primary endometrial cancer or prior primary endometrial cancer unless all of the following criteria are met:
    • Stage ≤ IB
    • Superficial myometrial invasion without vascular or lymphatic invasion
    • No poorly differentiated subtypes (i.e., papillary serous, clear cell, or other FIGO grade 3 lesions)


  • Must have undergone surgery for ovarian epithelial, primary peritoneal, or fallopian tube cancer in the past 1-12 weeks AND have tissue available for histologic evaluation
    • Patients with stage III disease in which the largest maximal diameter of any residual tumor implant a the completion of initial surgery is ≤ 1 cm will be defined as "optimal" (all others will be defined as "suboptimal")


  • Measurable or nonmeasurable disease


  • No tumor involving active major vessels


  • No prior or concurrent CNS disease, including primary brain tumor or brain metastases


Prior/Concurrent Therapy:

Biologic therapy

  • No prior targeted therapy for ovarian epithelial or peritoneal primary cancer, including, but not limited to, any of the following:
    • Vaccines
    • Antibodies
    • Tyrosine kinase inhibitors
  • No prior bevacizumab
  • No other prior antivascular endothelial growth factors (VEGF)
  • No other concurrent biologic therapy

Chemotherapy

  • See Disease Characteristics
  • No prior chemotherapy for abdominal or pelvic tumor including neoadjuvant chemotherapy for their ovarian or primary peritoneal cancer
  • More than 3 years since prior adjuvant chemotherapy for localized breast cancer AND patient remains free of recurrent or metastatic disease
  • No other concurrent chemotherapy

Endocrine therapy

  • Ovarian estrogen with or without progestin replacement therapy as indicated at the lowest effective dose(s) for control of menopausal symptoms at any time allowed
    • No progestins for management of anorexia while on study-directed therapy or prior to disease progression
  • No prior hormonal therapy for ovarian, peritoneal primary, or fallopian tube cancer
  • No concurrent hormonal therapy

Radiotherapy

  • More than 3 years since prior radiotherapy for localized cancer of the breast, head and neck, or skin AND patient remains free of recurrent or metastatic disease
  • No prior radiotherapy to the abdominal cavity or pelvis
  • No concurrent radiotherapy

Surgery

  • See Disease Characteristics
  • At least 4 weeks since prior major surgical procedure or open biopsy
  • At least 1 week since prior core biopsy
  • No concurrent major surgery including abdominal surgery (laparotomy or laparoscopy) prior to disease progression (e.g., colostomy or enterostomy reversal, interval or secondary cytoreductive surgery, or second look surgery

Other

  • No prior cancer therapy that would preclude study treatment
  • No concurrent consolidation or maintenance therapy
  • No other concurrent cytotoxic or anticancer therapy
  • No concurrent amifostine or other protective reagents

Patient Characteristics:

Performance status

  • GOG 0-2

Life expectancy

  • Not specified

Hematopoietic

  • Absolute neutrophil count ≥ 1,500/mm3 without induction or support by granulocyte colony stimulating factors
  • Platelet count ≥ 100,000/mm3
  • No active bleeding
  • No known bleeding disorder or coagulopathy

Hepatic

  • Bilirubin ≤ 1.5 times upper limit of normal (ULN)
  • SGOT ≤ 2.5 times ULN
  • Alkaline phosphatase ≤ 2.5 times ULN
  • INR ≤ 1.5 (2-3 with stable-dose therapeutic warfarin for management of venous thrombosis including pulmonary thromboembolus)
  • PTT < 1.2 times ULN
  • No acute hepatitis

Renal

  • Creatinine ≤ 1.5 times ULN
  • Urine protein:creatinine ratio < 1.0

    OR

  • Urine protein < 1 g/24-hr urine collection

Cardiovascular

  • No New York Heart Association class II-IV congestive heart failure
  • No myocardial infarction or unstable angina within the past 6 months
  • No uncontrolled hypertension (i.e., blood pressure > 150/90 mm Hg)
  • No serious cardiac arrhythmia requiring medication except for patients with asymptomatic atrial fibrillation with a controlled ventricular rate
  • No other clinically significant cardiovascular disease
  • No clinically significant peripheral vascular disease ≥ grade 2
  • No history of cerebral vascular accident, transient ischemic attack, or subarachnoid hemorrhage within the past 6 months

Other

  • Not pregnant or nursing
  • Negative pregnancy test
  • Fertile patients must use effective contraception during and for 6 months after completion of study treatment
  • No neuropathy (sensory and motor) > grade 1
  • No known hypersensitivity to Chinese hamster ovary cell products or recombinant human or humanized antibodies
  • No other malignancy within the past 5 years except nonmelanoma skin cancer
  • No active infection that requires parenteral antibiotics
  • No serious nonhealing wound, ulcer, or bone fracture
  • No history of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess within the past 28 days
    • Granulating incisions healing by secondary intention with no evidence of fascial dehiscence or infection are allowed
  • No other pathological condition that would confer a high risk of bleeding
  • No uncontrolled seizures
  • No significant traumatic injury within the past 4 weeks
  • No clinical symptoms or signs of gastrointestinal obstruction that require parenteral hydration and/or nutrition
  • No other medical history or condition that, in the opinion of the investigator, would preclude study participation

Expected Enrollment

2000

A total of 2,000 patients will be accrued for this study.

Outcomes

Primary Outcome(s)

Progression-free survival measured by RECIST Criteria and Modified Rustin Criteria for CA-125 at baseline, prior to every other course of therapy, every 3 months for 2 years, every 6 months for 3 years, and then annually during follow-up

Secondary Outcome(s)

Overall survival
Severe toxicity and serious adverse events by NCI Common Toxicity Criteria version 3 at baseline, every course of therapy, every 3 months for 2 years, every 6 months for 3 years, and then annually during follow-up
Quality of life by Functional Assessment of Cancer Therapy-Ovarian (Fact-O) at baseline, prior to courses 4, 7, 13, and 21, and then at 6 months after study completion
Translational objectives by angiogenic markers and gene arrays at baseline
Response rate

Outline

This is a randomized, double-blind, placebo-controlled, multicenter study. Patients are stratified according to stage of disease (III vs IV) or initial performance status (0 vs 1 vs 2). Patients are randomized to 1 of 3 treatment arms.

  • Arm I: Patients receive paclitaxel IV over 3 hours and carboplatin IV over 30 minutes on day 1. Beginning in course 2, patients also receive placebo IV over 30-90 minutes on day 1. Treatment repeats every 21 days for 6 courses. Beginning in course 7, patients receive placebo alone IV over 30-90 minutes on day 1. Treatment with placebo repeats every 21 days for up to 22 courses in the absence of disease progression or unacceptable toxicity.


  • Arm II: Patients receive paclitaxel and carboplatin as in arm I. Beginning in course 2, patients also receive bevacizumab IV over 30-90 minutes on day 1.Treatment repeats every 21 days for 6 courses. Beginning in course 7, patients receive placebo alone IV over 30-90 minutes on day 1. Treatment with placebo repeats every 21 days for up to 22 courses in the absence of disease progression or unacceptable toxicity.


  • Arm III: Patients receive paclitaxel and carboplatin as in arm I. Beginning in course 2, patients also receive bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 21 days for 6 courses. Beginning in course 7, patients receive bevacizumab alone IV over 30-90 minutes on day 1. Treatment with bevacizumab repeats every 21 days for up to 22 courses in the absence of disease progression or unacceptable toxicity.


Quality of life is assessed at baseline, before courses 4, 7, 13, and 21, and then at 6 months after study completion.

After completion of study treatment, patients are followed periodically for at least 5 years.

Trial Contact Information

Trial Lead Organizations

Gynecologic Oncology Group

Robert Burger, MD, Protocol chair
Ph: 714-456-7971
Email: raburger@uci.edu
Gini Fleming, MD, Protocol co-chair
Ph: 773-702-6712; 888-824-0200
Email: gfleming@medicine.bsd.uchicago.edu

Trial Sites

U.S.A.
Alabama
  Anniston
 Regional Medical Center
 Ellen Spremulli
Ph: 256-235-5877
  Birmingham
 Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham
 Clinical Trials Office - Lurleen Wallace Comprehensive Cancer
Ph: 205-934-0309
  Huntsville
 Clearview Cancer Institute
 Clinical Trials Office - Clearview Cancer Institute
Ph: 256-705-4224
Alaska
  Anchorage
 Providence Cancer Center
 Clinical Trials Office - Providence Cancer Center
Ph: 907-261-3109
Arizona
  Scottsdale
 Mayo Clinic Scottsdale
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
Arkansas
  Fayetteville
 Highlands Oncology Group - Fayetteville
 Randall Hightower, MD
Ph: 479-575-9000
  Ft. Smith
 Hembree Mercy Cancer Center at St. Edward Mercy Medical Center
 John Wells, MD
Ph: 479-484-4700
California
  Arroyo Grande
 Arroyo Grande Community Hospital
 David Palchak, MD
Ph: 805-773-7127
  Burbank
 Providence Saint Joseph Medical Center - Burbank
 Clinical Trials Office - Providence Saint Joseph Medical Center - Burbank
Ph: 818-847-3220
  Castro Valley
 East Bay Radiation Oncology Center
 James Feusner, MD
Ph: 510-428-3689
 Eden Medical Center
 James Feusner, MD
Ph: 510-428-3689
 Valley Medical Oncology Consultants - Castro Valley
 James Feusner, MD
Ph: 510-428-3689
  Concord
 Cancer Care Center at John Muir Health - Concord Campus
 Clinical Trials Office - Cancer Care Center at John Muir Health - Concord Campus
Ph: 925-674-2580
  Fairfield
 North Bay Cancer Center
 Clinical Trials Office - North Bay Cancer Center
Ph: 707-429-6976
  Fremont
 Kaiser Permanente - Fremont
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 Valley Medical Oncology
 James Feusner, MD
Ph: 510-428-3689
  Fresno
 Cancer Care Associates
 Steven Hager, DO
Ph: 559-326-1222
  Fullerton
 Virginia K. Crosson Cancer Center at St. Jude Medical Center
 Clinical Trials Office - Virginia K. Crosson Cancer Center
Ph: 714-446-5642
  Hayward
 Kaiser Permanente Medical Center - Hayward
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  La Jolla
 Rebecca and John Moores UCSD Cancer Center
 Clinical Trials Office - Rebecca and John Moores UCSD Cancer Center
Ph: 858-822-5354
 Email: cancercto@ucsd.edu
  Loma Linda
 Loma Linda University Cancer Institute at Loma Linda University Medical Center
 Clinical Trials Office - Loma Linda University Cancer Institute
Ph: 909-558-3375
  Long Beach
 Todd Cancer Institute at Long Beach Memorial Medical Center
 Wendy Brewster, MD, PhD
Ph: 714-456-8020
  Los Angeles
 Jonsson Comprehensive Cancer Center at UCLA
 Clinical Trials Office - Jonsson Comprehensive Cancer Center at UCLA
Ph: 888-798-0719
 Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center
 Ilana Cass
Ph: 310-423-3277
 USC/Norris Comprehensive Cancer Center and Hospital
 Clinical Trials Office - USC/Norris Comprehensive Cancer Center and Hospital
Ph: 323-865-0451
  Martinez
 Contra Costa Regional Medical Center
 James Feusner, MD
Ph: 510-428-3689
  Modesto
 Memorial Medical Center
 Clinical Trials Office - Memorial Medical Center
Ph: 209-572-7116
  Oakland
 Alta Bates Summit Medical Center - Summit Campus
 Clinical Trials Office - Alta Bates Summit Medical Center - Summit Campus
Ph: 510-204-1414
 Bay Area Breast Surgeons, Incorporated
 James Feusner, MD
Ph: 510-428-3689
 CCOP - Bay Area Tumor Institute
 James Feusner, MD
Ph: 510-428-3689
 Kaiser Permanente Medical Center - Oakland
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 Larry G Strieff MD Medical Corporation
 James Feusner, MD
Ph: 510-428-3689
 Tom K Lee, Incorporated
 James Feusner, MD
Ph: 510-428-3689
  Orange
 Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center
 Clinical Trials Office - Chao Family Comprehensive Cancer Center
Ph: 877-UC-STUDY
 Email: ucstudy@uci.edu
  Pleasanton
 Valley Care Medical Center
 James Feusner, MD
Ph: 510-428-3689
 Valley Medical Oncology Consultants - Pleasanton
 James Feusner, MD
Ph: 510-428-3689
  Redding
 Mercy Regional Cancer Center at Mercy Medical Center
 Clinical Trials Office - Mercy Regional Cancer Center
Ph: 530-225-7471
  Redwood City
 Kaiser Permanente Medical Center - Redwood City
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Richmond
 Kaiser Permanente Medical Center - Richmond
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Roseville
 Kaiser Permanente Medical Center - Roseville
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 Sutter Cancer Center at Roseville Medical Center
 Clinical Trials Office - Sutter Cancer Center
Ph: 916-454-6595
  Sacramento
 Kaiser Permanente Medical Center - Sacramento
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 South Sacramento Kaiser-Permanente Medical Center
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 Sutter Cancer Center
 Clinical Trial Office - Sutter Cancer Center
Ph: 916-454-6595
 University of California Davis Cancer Center
 Clinical Trials Office - University of California Davis Cancer Center
Ph: 916-734-3089
  San Francisco
 Kaiser Permanente Medical Center - San Francisco Geary Campus
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 San Francisco General Hospital Medical Center
 John Chan
Ph: 415-206-8000
 UCSF Helen Diller Family Comprehensive Cancer Center
 Clinical Trials Office - UCSF Helen Diller Family Comprehensive Cancer Center
Ph: 877-827-3222
  San Jose
 Kaiser Permanente Medical Center - Santa Teresa
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  San Pablo
 Doctors Medical Center - San Pablo Campus
 James Feusner, MD
Ph: 510-428-3689
  San Rafael
 Kaiser Foundation Hospital - San Rafael
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Sana Rosa
 CCOP - Santa Rosa Memorial Hospital
 Ian Anderson, MD
Ph: 707-521-3830
  Santa Clara
 Kaiser Permanente Medical Center - Santa Clara Kiely Campus
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Santa Rosa
 Kaiser Permanente Medical Center - Santa Rosa
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  South San Francisco
 Kaiser Permanente Medical Center - South San Francisco
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Stanford
 Stanford Cancer Center
 Clinical Trials Office - Stanford Cancer Center
Ph: 650-498-7061
 Email: cctoffice@stanford.edu
  Stockton
 Kaiser Permanente Medical Facility - Stockton
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Vallejo
 Kaiser Permanente Medical Center - Vallejo
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Walnut Creek
 John Muir/Mt. Diablo Comprehensive Cancer Center
 Clinical Trials Office - John Muir/Mt. Diablo Comprehensive Cancer Center
Ph: 925-941-4246
 Kaiser Permanente Medical Center - Walnut Creek
 Louis Fehrenbacher, MD
Ph: 707-651-2577
Colorado
  Aurora
 Aurora Presbyterian Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 Colorado Gynecologic Oncology Group, PC
 Susan Davidson, MD
Ph: 303-315-7897
  Boulder
 Boulder Community Hospital
 Clinical Trials Office - Boulder Community Hospital
Ph: 303-938-5253
  Colorado Springs
 Memorial Hospital Cancer Center - Colorado Springs
 Clinical Trials Office - Memorial Hospital
Ph: 719-365-2406
 Penrose Cancer Center at Penrose Hospital
 Clinical Trials Office - Penrose Cancer Center
Ph: 719-776-5275
  Denver
 CCOP - Colorado Cancer Research Program
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 Porter Adventist Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 Presbyterian - St. Luke's Medical Center
 Clinical Trials Office - Presbyterian - St. Luke's Medical Center
Ph: 303-839-6000
 Rose Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 St. Anthony Central Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 St. Joseph Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Englewood
 Rocky Mountain Gynecologic Oncology
 Kevin Davis, MD
Ph: 303-781-9090
 Swedish Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Grand Junction
 St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Greeley
 North Colorado Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Lone Tree
 Sky Ridge Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Longmont
 Hope Cancer Care Center at Longmont United Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Loveland
 McKee Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Pueblo
 St. Mary - Corwin Regional Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Thornton
 North Suburban Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Wheat Ridge
 Exempla Lutheran Medical Center
 Clinical Trials Office - Exempla Lutheran Medical Center
Ph: 303-403-3605
Connecticut
  Bridgeport
 Bridgeport Hospital
 Clinical Trials Office - Bridgeport Hospital
Ph: 203-384-4869
  Hartford
 Helen and Harry Gray Cancer Center at Hartford Hospital
 Clinical Trials Office - Helen and Harry Gray Cancer Center
Ph: 860-545-5363
 Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center
 Beth Nelson
Ph: 860-714-4680
  New Britain
 George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus
 Clinical Trials Office - George Bray Cancer Center
Ph: 860-224-5660
  New Haven
 Yale Cancer Center
 Clinical Trials Office - Yale Cancer Center
Ph: 203-785-5702
  Stamford
 Carl and Dorothy Bennett Cancer Center at Stamford Hospital
 Clinical Trials Office - Carl and Dorothy Bennett Cancer Center
Ph: 203-323-8944
  Torrington
 Connecticut Oncology & Hematology - Torrington
 Michael Magnifico, MD
Ph: 860-482-5384
Delaware
  Lewes
 Tunnell Cancer Center at Beebe Medical Center
 Clinical Trials Office - Tunnell Cancer Center
Ph: 302-645-3171
  Newark
 CCOP - Christiana Care Health Services
 Clinical Trial Office - CCOP - Christiana Care Health Services
Ph: 302-733-6227
District of Columbia
  Washington
 Walter Reed Army Medical Center
 Clinical Trials Office - Walter Reed Army Medical Center
Ph: 202-782-7840
Florida
  Clearwater
 Morton Plant Hospital
 Hector Arango, MD
Ph: 727-446-2111
  Fort Lauderdale
 Broward General Medical Center Cancer Center
 Clinical Trials Office - Broward General Medical Center Cancer Center
Ph: 954-355-5346
 Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
 Clinical Trials Office - Michael and Dianne Bienes Comprehensive Cancer Center
Ph: 954-776-3239
  Fort Myers
 Florida Gynecologic Oncology - Fort Myers
 Edward Grendys, MD
Ph: 239-992-0077
  Jacksonville
 Mayo Clinic - Jacksonville
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
 St. Vincent's Medical Center
 Stephen Buckley, MD
Ph: 904-389-3993
  Lakeland
 Center for Cancer Care and Research at Watson Clinic, LLP
 Clinical Trials Office - Center for Cancer Care and Research
Ph: 863-680-7780
  Miami
 University of Miami Sylvester Comprehensive Cancer Center - Miami
 University of Miami Sylvester Comprehensive Cancer Center Clinical Trial Matching Service
Ph: 866-574-5124
 Email: Sylvester@emergingmed.com
  Miami Beach
 CCOP - Mount Sinai Medical Center
 Rogerio Lilenbaum, MD
Ph: 305-535-3310
  Orlando
 Florida Hospital Cancer Institute at Florida Hospital Orlando
 Clinical Trials Office - Florida Hospital Cancer Institute
Ph: 407-303-5623
 M.D. Anderson Cancer Center at Orlando
 Alan Gordon
Ph: 407-648-3800
800-648-3818
  West Palm Beach
 Palm Beach Cancer Institute - West Palm Beach
 Daniel Spitz
Ph: 561-366-4117
Georgia
  Augusta
 MBCCOP - Medical College of Georgia Cancer Center
 Sharad Ghamande, MD
Ph: 706-721-3992
  Macon
 Central Georgia Gynecologic Oncology
 Gary Eddy, MD
Ph: 476-633-6090
  Savannah
 Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
 Clinical Trials Office - Curtis and Elizabeth Anderson Cancer Institute
Ph: 912-350-8568
Hawaii
  Aiea
 Kapiolani Medical Center at Pali Momi
 Michael Carney, MD
Ph: 808-983-6090
  Honolulu
 Hawaii Medical Center - East
 Michael Carney, MD
Ph: 808-983-6090
 Kapiolani Medical Center for Women and Children
 Michael Carney, MD
Ph: 808-983-6090
 MBCCOP - Hawaii
 Michael Carney, MD
Ph: 808-983-6090
 OnCare Hawaii, Incorporated - Kuakini
 Michael Carney, MD
Ph: 808-983-6090
 OnCare Hawaii, Incorporated - Lusitana
 Michael Carney, MD
Ph: 808-983-6090
 Queen's Cancer Institute at Queen's Medical Center
 Michael Carney, MD
Ph: 808-983-6090
 Straub Clinic and Hospital, Incorporated
 Michael Carney, MD
Ph: 808-983-6090
  Wailuku
 Maui Memorial Medical Center
 Michael Carney, MD
Ph: 808-983-6090
 Pacific Cancer Institute - Maui
 Michael Carney, MD
Ph: 808-983-6090
Illinois
  Alton
 Saint Anthony's Hospital at Saint Anthony's Health Center
 Bethany Sleckman, MD
Ph: 314-251-7057
  Aurora
 Rush-Copley Cancer Care Center
 Kendrith Rowland, MD
Ph: 217-383-3019
  Bloomington
 St. Joseph Medical Center
 John Kugler, MD
Ph: 309-243-3605
  Canton
 Graham Hospital
 John Kugler, MD
Ph: 309-243-3605
  Carthage
 Memorial Hospital
 John Kugler, MD
Ph: 309-243-3605
  Chicago
 Mount Sinai Hospital Medical Center
 Ervin Hire, MD
Ph: 231-487-3578
 Resurrection Medical Center
 Christopher Rose, MD
Ph: 847-965-3200
 Robert H. Lurie Comprehensive Cancer Center at Northwestern University
 Clinical Trials Office - Robert H. Lurie Comprehensive Cancer Center at Northwestern University
Ph: 312-695-1301
 Email: cancer@northwestern.edu
 Rush University Medical Center
 Clinical Trials Office - Rush University Medical Center
Ph: 312-942-5498
 Email: clinical_trials@rush.edu
 Swedish Covenant Hospital
 K. Joseph Philip, MD
Ph: 773-784-6676
 University of Chicago Cancer Research Center
 Clinical Trials Office - University of Chicago Cancer Research Center
Ph: 773-834-7424
 University of Illinois Cancer Center
 Clinical Trial Office - University of Illinois Cancer Center
Ph: 312-355-3046
  Decatur
 Decatur Memorial Hospital Cancer Care Institute
 Clinical Trials Office - Decatur Memorial Hospital Cancer Care Institute
Ph: 217-876-6601
  Eureka
 Eureka Community Hospital
 John Kugler, MD
Ph: 309-243-3605
  Evanston
 Evanston Northwestern Healthcare - Evanston Hospital
 Clinical Trials Office - Evanston Northwestern Healthcare - Evanston Hospital
Ph: 847-570-1381
 St. Francis Hospital
 K. Joseph Philip, MD
Ph: 773-784-6676
  Galesburg
 Galesburg Clinic, PC
 John Kugler, MD
Ph: 309-243-3605
 Galesburg Cottage Hospital
 John Kugler, MD
Ph: 309-243-3605
  Harvey
 Ingalls Cancer Care Center at Ingalls Memorial Hospital
 Clinical Trials Office - Ingalls Cancer Care Center at Ingalls Memorial Hospital
Ph: 708-915-6747
  Havana
 Mason District Hospital
 John Kugler, MD
Ph: 309-243-3605
  Hinsdale
 Hinsdale Hematology Oncology Associates
 Sudarshan Sharma, MD
Ph: 630-856-6757
  Hopedale
 Hopedale Medical Complex
 John Kugler, MD
Ph: 309-243-3605
  Kankakee
 Provena St. Mary's Regional Cancer Center - Kankakee
 Riaz Elahi, MD
Ph: 708-873-4500
  La Grange
 La Grange Memorial Hospital
 Clinical Trials Office - La Grange Memorial Hospital
Ph: 630-856-7526
  Macomb
 McDonough District Hospital
 John Kugler, MD
Ph: 309-243-3605
  Maywood
 Cardinal Bernardin Cancer Center at Loyola University Medical Center
 Clinical Trials Office - Cardinal Bernardin Cancer Center
Ph: 708-226-4357
  Moline
 Costas Constantinou, MD
Ph: 563-359-9876
 Trinity Cancer Center at Trinity Medical Center - 7th Street Campus
 Costas Constantinou, MD
Ph: 563-359-9876
  Mt. Vernon
 Good Samaritan Regional Health Center
 Bethany Sleckman, MD
Ph: 314-251-7057
  Normal
 BroMenn Regional Medical Center
 John Kugler, MD
Ph: 309-243-3605
 Community Cancer Center
 John Kugler, MD
Ph: 309-243-3605
  Ottawa
 Community Hospital of Ottawa
 John Kugler, MD
Ph: 309-243-3605
 Oncology Hematology Associates of Central Illinois, PC - Ottawa
 John Kugler, MD
Ph: 309-243-3605
  Park Ridge
 Advocate Lutheran General Cancer Care Center
 Clinical Trials Office - Advocate Lutheran General Cancer Care Center
Ph: 847-384-3621
  Pekin
 Cancer Treatment Center at Pekin Hospital
 John Kugler, MD
Ph: 309-243-3605
  Peoria
 CCOP - Illinois Oncology Research Association
 John Kugler, MD
Ph: 309-243-3605
 Methodist Medical Center of Illinois
 Clinical Trials Office - Methodist Medical Center of Illinois
Ph: 309-243-3000
 Oncology Hematology Associates of Central Illinois, PC - Peoria
 John Kugler, MD
Ph: 309-243-3605
 OSF St. Francis Medical Center
 John Kugler, MD
Ph: 309-243-3605
 Proctor Hospital
 John Kugler, MD
Ph: 309-243-3605
  Peru
 Illinois Valley Community Hospital
 John Kugler, MD
Ph: 309-243-3605
  Princeton
 Perry Memorial Hospital
 John Kugler, MD
Ph: 309-243-3605
  Rockford
 Center for Cancer Care at OSF Saint Anthony Medical Center
 Clinical Trials Office - Center for Cancer Care at OSF Saint Anthony Medical Center
Ph: 815-227-2633
 Swedish-American Regional Cancer Center
 Clinical Trials Office - Swedish-American Regional Cancer Center
Ph: 815-489-4413
  Spring Valley
 St. Margaret's Hospital
 John Kugler, MD
Ph: 309-243-3605
  Springfield
 Regional Cancer Center at Memorial Medical Center
 Clinical Trials Office - Regional Cancer Center at Memorial Medical Center
Ph: 217-788-4233
  Urbana
 Carle Cancer Center at Carle Foundation Hospital
 Clinical Trials Office - Carle Cancer Center
Ph: 800-446-5532
 CCOP - Carle Cancer Center
 Clinical Trials Office - CCOP - Carle Cancer Center
Ph: 800-446-5532
  Winfield
 Central Dupage Cancer Center
 Laura Horvath
Ph: 630-933-1600
Indiana
  Beech Grove
 St. Francis Hospital and Health Centers - Beech Grove Campus
 Max Clark, DO
Ph: 937-429-2410
  Elkhart
 Elkhart General Hospital
 Michael Method, MD, MPH
Ph: 574-237-1328
  Fort Wayne
 Fort Wayne Medical Oncology and Hematology
 Sreenivasa Nattam, MD
Ph: 260-484-8830
  Indianapolis
 Indiana University Melvin and Bren Simon Cancer Center
 Clinical Trials Office - Indiana University Cancer Center
Ph: 317-274-2552
 St. Vincent Indianapolis Hospital
 Clinical Trials Office - St. Vincent Indianapolis Hospital
Ph: 317-338-2194
  Kokomo
 Howard Community Hospital
 Michael Method, MD, MPH
Ph: 574-237-1328
  La Porte
 Center for Cancer Therapy at LaPorte Hospital and Health Services
 Michael Method, MD, MPH
Ph: 574-237-1328
  Michigan City
 Saint Anthony Memorial Health Centers
 Kendrith Rowland, MD
Ph: 217-383-3019
  Munster
 Community Hospital
 Erwin Robin, MD
Ph: 219-836-2860
  Richmond
 Reid Hospital & Health Care Services
 Max Clark, DO
Ph: 937-429-2410
  South Bend
 CCOP - Northern Indiana CR Consortium
 Michael Method, MD, MPH
Ph: 574-237-1328
 Memorial Hospital of South Bend
 Clinical Trials Office - Memorial Hospital of South Bend
Ph: 800-284-7370
 Saint Joseph Regional Medical Center
 Michael Method, MD, MPH
Ph: 574-237-1328
 South Bend Clinic
 Michael Method, MD, MPH
Ph: 574-237-1328
Iowa
  Ames
 McFarland Clinic, PC
 Clinical Trials Office - McFarland Clinic, PC
Ph: 515-239-2621
  Bettendorf
 Costas Constantinou, MD
Ph: 563-359-9876
 Hematology Oncology Associates of the Quad Cities
 Shobha Chitneni, MD, MBBS
Ph: 563-355-7733
  Cedar Rapids
 Cedar Rapids Oncology Associates
 Clinical Trials Office - Cedar Rapids Oncology Associates
Ph: 319-363-2690
  Davenport
 Genesis Medical Center - West Campus
 George Kovach, MD
Ph: 563-421-1960
 Genesis Regional Cancer Center at Genesis Medical Center
 George Kovach, MD
Ph: 563-421-1960
  Des Moines
 CCOP - Iowa Oncology Research Association
 Roscoe Morton, MD, FACP
Ph: 515-282-2921
 John Stoddard Cancer Center at Iowa Lutheran Hospital
 Clinical Trials Office - John Stoddard Cancer Center at Iowa Lutheran Hospital
Ph: 515-241-8704
 John Stoddard Cancer Center at Iowa Methodist Medical Center
 Clinical Trials Office - John Stoddard Cancer Center at Iowa Methodist Medical Center
Ph: 515-241-6727
 Medical Oncology and Hematology Associates at John Stoddard Cancer Center
 Roscoe Morton, MD, FACP
Ph: 515-282-2921
 Medical Oncology and Hematology Associates at Mercy Cancer Center
 Roscoe Morton, MD, FACP
Ph: 515-282-2921
 Mercy Cancer Center at Mercy Medical Center - Des Moines
 Roscoe Morton, MD, FACP
Ph: 515-282-2921
 Mercy Capitol Hospital
 Roscoe Morton, MD, FACP
Ph: 515-282-2921
  Iowa City
 Holden Comprehensive Cancer Center at University of Iowa
 Cancer Information Service
Ph: 800-237-1225
  Mason City
 Mercy Cancer Center at Mercy Medical Center - North Iowa
 Clinical Trials Office - Mercy Cancer Center at Mercy Medical Center - North Iowa
Ph: 641-422-6304
  Sioux City
 Mercy Medical Center - Sioux City
 Donald Wender, MD, PhD
Ph: 712-252-0088
 Siouxland Hematology-Oncology Associates, LLP
 Donald Wender, MD, PhD
Ph: 712-252-0088
 St. Luke's Regional Medical Center
 Donald Wender, MD, PhD
Ph: 712-252-0088
  Waterloo
 Cedar Valley Medical Specialists, PC - West Ridgeway Avenue
 Boriana Kamenova
Ph: 319-833-5907
 Covenant Cancer Treatment Center
 Clinical Trials Office - Covenant Cancer Treatment Center
Ph: 319-272-2070
Kansas
  Chanute
 Cancer Center of Kansas, PA - Chanute
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Dodge City
 Cancer Center of Kansas, PA - Dodge City
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  El Dorado
 Cancer Center of Kansas, PA - El Dorado
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Independence
 Cancer Center of Kansas-Independence
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Kansas City
 Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
 Clinical Trials Office - Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
Ph: 913-588-4709
  Kingman
 Cancer Center of Kansas, PA - Kingman
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Lawrence
 Lawrence Memorial Hospital
 Rakesh Gaur, MD
Ph: 816-823-0555
  Liberal
 Southwest Medical Center
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Newton
 Cancer Center of Kansas, PA - Newton
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Overland Park
 Menorah Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
  Parsons
 Cancer Center of Kansas, PA - Parsons
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Pratt
 Cancer Center of Kansas, PA - Pratt
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Salina
 Cancer Center of Kansas, PA - Salina
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Shawnee Mission
 Shawnee Mission Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
  Topeka
 Cotton-O'Neil Cancer Center
 Clinical Trials Office - Cotton-O'Neil Cancer Center
Ph: 785-270-4963
  Wellington
 Cancer Center of Kansas, PA - Wellington
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Wichita
 Associates in Womens Health, PA - North Review
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Cancer Center of Kansas, PA - Wichita
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Cancer Center of Kansas, PA - Medical Arts Tower
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 CCOP - Wichita
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Via Christi Cancer Center at Via Christi Regional Medical Center
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Wesley Medical Center
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Winfield
 Cancer Center of Kansas, PA - Winfield
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
Kentucky
  Edgewood
 Esther Marie Hatton Cancer Care Center at St. Elizabeth Medical Center
 Jack Basil, MD
Ph: 513-872-3401
  Lexington
 Lucille P. Markey Cancer Center at University of Kentucky
 Clinical Trials Office - Markey Cancer Center at University of Kentucky Chandler Medical Center
Ph: 859-257-3379
  Louisville
 James Graham Brown Cancer Center at University of Louisville
 Edward Helm, MD, FACS, MHA
Ph: 504-568-4765
 Louisville Oncology at Norton Cancer Institute - Louisville
 Clinical Trials Office - Louisville Oncology
Ph: 502-629-2500
Louisiana
  New Orleans
 Ochsner Cancer Institute at Ochsner Clinic Foundation
 Richard Kline, MD
Ph: 504-842-4165
  Shreveport
 Christus Schumpert Cancer Treatment Center
 Clinical Trials Office - Christus Schumpert Cancer Treatment Center
Ph: 318-681-4763
Maine
  Bangor
 CancerCare of Maine at Eastern Maine Medical Center
 Clinical Trials Office - CancerCare of Maine
Ph: 207-973-4274
  Portland
 Maine Medical Center - Bramhall Campus
 Clinical Trials Office - Maine Medical Center - Bramhall Campus
Ph: 207-885-7565
Maryland
  Baltimore
 Harry & Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center
 Clinical Trials Office - Harry & Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center
Ph: 443-777-7364
 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
 Clinical Trials Office - Sidney Kimmel Comprehensive Cancer Center at John Hopkins
Ph: 410-955-8804
 Email: jhcccro@jhmi.edu
  Easton
 Shore Regional Cancer Center at Memorial Hospital - Easton
 Mary DeShields, MD
Ph: 410-819-3332
  Elkton MD
 Union Hospital Cancer Program at Union Hospital
 Mark Borowsky
Ph: 410-398-4000
  Frederick
 Frederick Memorial Hospital Regional Cancer Therapy Center
 Paul Rausch, MD
Ph: 301-662-8477
  Kensington
 Associates in Oncology and Hematology
 Joseph Haggerty
Ph: 301-929-0765
  Largo
 Kaiser Permanente Mid-Atlantic Medical Group-Largo Medical Facility
 Leon Hwang, MD
Ph: 301-548-5768
  Lutherville
 Kaiser Permanente - Towson
 Leon Hwang, MD
Ph: 301-548-5768
  Rockville
 Associates in Oncology and Hematology - Medical Center Drive
 Joseph Haggerty
Ph: 301-424-6231
 Kaiser Permanente Capital Area Medical Group - Shady Grove Facility
 Leon Hwang, MD
Ph: 301-548-5768
  Silver Spring
 Holy Cross Hospital
 Clinical Trials Office - Holy Cross Hospital
Ph: 310-754-7552
Massachusetts
  Burlington
 Lahey Clinic Medical Center - Burlington
 Clinical Trials Office - Lahey Clinic Medical Center - Burlington
Ph: 781-744-8027
  Pittsfield
 Berkshire Hematology Oncology, PC
 Harvey Zimbler, MD
Ph: 413-496-8205
  Springfield
 Baystate Regional Cancer Program at D'Amour Center for Cancer Care
 Wilson Mertens
Ph: 413-794-9338
  Worcester
 UMASS Memorial Cancer Center - University Campus
 Susan Zweizig, MD
Ph: 508-334-1160
Michigan
  Adrian
 Hickman Cancer Center at Bixby Medical Center
 Clinical Trials Office - Hickman Cancer Center at Bixby Medical Center
Ph: 517-265-0116
  Ann Arbor
 CCOP - Michigan Cancer Research Consortium
 Philip Stella, MD
Ph: 734-712-1000
 Saint Joseph Mercy Cancer Center
 Philip Stella, MD
Ph: 734-712-1000
 University of Michigan Comprehensive Cancer Center
 Clinical Trials Office - University of Michigan Comprehensive Cancer Center
Ph: 800-865-1125
  Battle Creek
 Battle Creek Health System Cancer Care Center
 Marianne Lange, MD
Ph: 616-977-6243
  Big Rapids
 Mecosta County Medical Center
 Marianne Lange, MD
Ph: 616-977-6243
  Dearborn
 Oakwood Cancer Center at Oakwood Hospital and Medical Center
 Clinical Trials Office - Oakwood Cancer Center at Oakwood Hospital and Medical Center
Ph: 313-593-8090
  Detroit
 Barbara Ann Karmanos Cancer Institute
 Clinical Trials Office - Barbara Ann Karmanos Cancer Institute
Ph: 313-576-9363
  Escanaba
 Green Bay Oncology, Limited - Escanaba
 Jonathan Tammela
Ph: 800-432-6049
  Flint
 Genesys Hurley Cancer Institute
 Clinical Trials Office - Genesys Hurley Cancer Institute
Ph: 810-762-8057
 Hurley Medical Center
 Clinical Trials Office - Hurley Medical Center
Ph: 810-762-8057
  Grand Rapids
 Butterworth Hospital at Spectrum Health
 Marianne Lange, MD
Ph: 616-977-6243
 CCOP - Grand Rapids
 Marianne Lange, MD
Ph: 616-977-6243
 Gynecologic Oncology of West Michigan
 Gordon Downey, MD
Ph: 616-957-3398
 Lacks Cancer Center at Saint Mary's Health Care
 Marianne Lange, MD
Ph: 616-977-6243
  Grosse Pointe Woods
 Van Elslander Cancer Center at St. John Hospital and Medical Center
 Clincial Trials Office - Van Elslander Cancer Center at St. John Hospital and Medical Center
Ph: 313-343-3166
  Holland
 Holland Community Hospital
 Marianne Lange, MD
Ph: 616-977-6243
  Iron Mountain
 Dickinson County Healthcare System
 Jonathan Tammela
Ph: 906-774-1313
  Jackson
 Foote Memorial Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Kalamazoo
 Borgess Medical Center
 Raymond Lord, MD
Ph: 269-373-7458
 Bronson Methodist Hospital
 Raymond Lord, MD
Ph: 269-373-7458
 West Michigan Cancer Center
 Clinical Trials Office - West Michigan Cancer Center
Ph: 269-373-7458
  Lambertville
 Haematology-Oncology Associates of Ohio and Michigan, PC
 Paul Schaefer, MD
Ph: 419-479-5605
  Lansing
 Sparrow Regional Cancer Center
 Clinical Trials Office - Sparrow Regional Cancer Center
Ph: 517-364-2890
  Livonia
 St. Mary Mercy Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Monroe
 Community Cancer Center of Monroe
 Paul Schaefer, MD
Ph: 419-479-5605
 Mercy Memorial Hospital - Monroe
 Paul Schaefer, MD
Ph: 419-479-5605
  Muskegon
 Hackley Hospital
 Marianne Lange, MD
Ph: 616-977-6243
  Petoskey
 Northern Michigan Hospital
 Marianne Lange, MD
Ph: 616-977-6243
  Port Huron
 Mercy Regional Cancer Center at Mercy Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Saginaw
 Seton Cancer Institute at Saint Mary's - Saginaw
 Clinical Trials Office - Seton Cancer Institute - Saginaw
Ph: 989-776-8411
  Southfield
 Providence Cancer Institute at Providence Hospital - Southfield Campus
 Vinay Malviya, MD, FACOG, FACS
Ph: 248-849-8140
  St. Joseph
 Lakeland Regional Cancer Care Center - St. Joseph
 Michael Method, MD, MPH
Ph: 574-237-1328
  Traverse City
 Munson Medical Center
 Marianne Lange, MD
Ph: 616-977-6243
  Warren
 St. John Macomb Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Wyoming
 Metro Health Hospital
 Marianne Lange, MD
Ph: 616-977-6243
Minnesota
  Burnsville
 Fairview Ridges Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Coon Rapids
 Mercy and Unity Cancer Center at Mercy Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Duluth
 CCOP - Duluth
 Daniel Nikcevich, MD, PhD
Ph: 218-786-3625
 Duluth Clinic Cancer Center - Duluth
 Clinical Trials Office - Duluth Clinic Cancer Center - Duluth
Ph: 218-786-3308
 Miller - Dwan Medical Center
 Daniel Nikcevich, MD, PhD
Ph: 218-786-3625
 St. Luke's Hospital Cancer Care Center
 Tanya Repka, MD, FACP
Ph: 218-726-3081
  Edina
 Fairview Southdale Hospital
 Clinical Trials Office - Fairview Southdale Hospital
Ph: 612-625-3650
  Fridley
 Mercy and Unity Cancer Center at Unity Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Maplewood
 Minnesota Oncology Hematology, PA - Maplewood
 Patrick Flynn, MD
Ph: 612-863-8585
  Minneapolis
 Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
 Clinical Trials Office - Virginia Piper Cancer Institute
Ph: 612-863-5654
  Robbinsdale
 Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
 Clinical Trials Office - Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
Ph: 763-520-1893
  Rochester
 Mayo Clinic Cancer Center
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
  Saint Louis Park
 CCOP - Metro-Minnesota
 Patrick Flynn, MD
Ph: 612-863-8585
 Park Nicollet Cancer Center
 Patrick Flynn, MD
Ph: 612-863-8585
  Saint Paul
 United Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Shakopee
 St. Francis Cancer Center at St. Francis Medical Center
 Patrick Flynn, MD
Ph: 612-863-8585
  Waconia
 Ridgeview Medical Center
 Patrick Flynn, MD
Ph: 612-863-8585
  Woodbury
 Minnesota Oncology Hematology, PA - Woodbury
 Patrick Flynn, MD
Ph: 612-863-8585
Mississippi
  Jackson
 St. Dominic Cancer Center
 Donald Seago
Ph: 601-200-3070
 University of Mississippi Cancer Clinic
 James Thigpen, MD
Ph: 601-984-5590
  Pascagoula
 Regional Cancer Center at Singing River Hospital
 James Clarkson, MD
Ph: 228-374-6296
Missouri
  Cape Girardeau
 Saint Francis Medical Center
 Bethany Sleckman, MD
Ph: 314-251-7057
 Southeast Missouri Regional Cancer Center at Southeast Missouri Hospital
 Bethany Sleckman, MD
Ph: 314-251-7057
  Independence
 Independence Regional Health Center
 Rakesh Gaur, MD
Ph: 816-823-0555
  Jefferson City
 Capital Region Cancer Center
 Tamara Hopkins
Ph: 573-632-5482
  Joplin
 Freeman Cancer Institute at Freeman Health System
 Anisa Hassan
Ph: 417-347-3066
  Kansas City
 CCOP - Kansas City
 Rakesh Gaur, MD
Ph: 816-823-0555
 North Kansas City Hospital
 Rakesh Gaur, MD
Ph: 816-823-0555
 Parvin Radiation Oncology
 Rakesh Gaur, MD
Ph: 816-823-0555
 Research Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
 Saint Luke's Cancer Institute at Saint Luke's Hospital
 Rakesh Gaur, MD
Ph: 816-823-0555
 St. Joseph Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
 Truman Medical Center - Hospital Hill
 Rakesh Gaur, MD
Ph: 816-823-0555
  Liberty
 Liberty Hospital
 Rakesh Gaur, MD
Ph: 816-823-0555
  Saint Joseph
 Heartland Regional Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
  Saint Louis
 Arch Medical Services, Incorporated at Center for Cancer Care and Research
 Alan Lyss, MD
Ph: 314-996-5514
 CCOP - St. Louis-Cape Girardeau
 Bethany Sleckman, MD
Ph: 314-251-7057
 David C. Pratt Cancer Center at St. John's Mercy
 Clinical Trials Office - David C. Pratt Cancer Center at St. John's Mercy
Ph: 314-251-6770
 Midwest Hematology Oncology Group, Incorporated
 Bethany Sleckman, MD
Ph: 314-251-7057
 Missouri Baptist Cancer Center
 Alan Lyss, MD
Ph: 314-996-5514
 Saint Louis University Cancer Center
 Clinical Trials Office - Saint Louis University Cancer Center
Ph: 314-977-4440
 Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
 David Mutch, MD
Ph: 314-362-3181
  Springfield
 CCOP - Cancer Research for the Ozarks
 Robert Carolla
Ph: 417-269-4520
 Hulston Cancer Center at Cox Medical Center South
 John Goodwin, MD
Ph: 417-269-4520
 St. John's Regional Health Center
 Robert Carolla
Ph: 417-820-2000
Montana
  Billings
 Billings Clinic - Downtown
 Clinical Trials Office - Billings Clinic - Downtown
Ph: 800-996-2663
 Email: research@billingsclinic.org
 CCOP - Montana Cancer Consortium
 Benjamin Marchello, MD
Ph: 406-238-6290
 Hematology-Oncology Centers of the Northern Rockies - Billings
 Benjamin Marchello, MD
Ph: 406-238-6290
 Northern Rockies Radiation Oncology Center
 Benjamin Marchello, MD
Ph: 406-238-6290
 St. Vincent Healthcare Cancer Care Services
 Benjamin Marchello, MD
Ph: 406-238-6290
  Butte
 St. James Healthcare Cancer Care
 Benjamin Marchello, MD
Ph: 406-238-6290
  Great Falls
 Benjamin Marchello, MD
Ph: 406-238-6290
 Big Sky Oncology
 Clinical Trail Office - Big Sky Oncology
Ph: 406-731-8217
 Great Falls Clinic - Main Facility
 Benjamin Marchello, MD
Ph: 406-238-6290
 Sletten Cancer Institute at Benefis Healthcare
 Grant Harrer, MD, FACP, CCTI
Ph: 406-731-8100
  Havre
 Northern Montana Hospital
 Benjamin Marchello, MD
Ph: 406-238-6290
  Kalispell
 Glacier Oncology, PLLC
 Benjamin Marchello, MD
Ph: 406-238-6290
 Kalispell Medical Oncology at KRMC
 Benjamin Marchello, MD
Ph: 406-238-6290
 Kalispell Regional Medical Center
 Benjamin Marchello, MD
Ph: 406-238-6290
  Missoula
 Community Medical Center
 Benjamin Marchello, MD
Ph: 406-238-6290
 Guardian Oncology and Center for Wellness
 Benjamin Marchello, MD
Ph: 406-238-6290
 Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
 Clinical Trials Office - Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
Ph: 406-329-7029
 Montana Cancer Specialists at Montana Cancer Center
 Clinical Trials Office - Montana Cancer Specialists at Montana Cancer Center
Ph: 406-238-6962
Nebraska
  Kearney
 Good Samaritan Cancer Center at Good Samaritan Hospital
 Clinical Trials Office - Good Samaritan Cancer Center at Good Samaritan Hospital
Ph: 308-865-7963
  Omaha
 Alegant Health Cancer Center at Bergan Mercy Medical Center
 Clinical Trials Office - Alegant Health Cancer Center at Bergen Mercy Medical Center
Ph: 402-398-6060
 CCOP - Missouri Valley Cancer Consortium
 Gamini Soori, MD, FACP, FRCP, MBA
Ph: 402-393-3110
 Creighton University Medical Center
 Clinical Trials Office - Creighton University Medical Center
Ph: 402-280-4100
 Immanuel Medical Center
 Gamini Soori, MD, FACP, FRCP, MBA
Ph: 402-393-3110
 Methodist Estabrook Cancer Center
 Peter Morris, MD
Ph: 402-354-5250
 UNMC Eppley Cancer Center at the University of Nebraska Medical Center
 Clinical Trials Office - UNMC Eppley Cancer Center at the University of Nebraska Medical Center
Ph: 800-999-5465
Nevada
  Las Vegas
 Women's Cancer Center - Lake Mead
 Nick Spirtos, MD
Ph: 408-866-3843
  Reno
 Renown Institute for Cancer at Renown Regional Medical Center
 Peter Lim
Ph: 775-982-5050
866-559-0558
 Saint Mary's Regional Medical Center
 Peter Lim
Ph: 775-770-3194
New Hampshire
  Concord
 New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
 Charles Catcher, MD
Ph: 603-224-2556
  Exeter
 Center for Cancer Care at Exeter Hospital
 Danny Sims
Ph: 603-580-6636
  Hooksett
 New Hampshire Oncology - Hematology, PA - Hooksett
 Charles Catcher, MD
Ph: 603-224-2556
  Lebanon
 Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center
 Clinical Trials Office - Norris Cotton Cancer Center
Ph: 603-650-7609
 Email: cancerhelp@dartmouth.edu
New Jersey
  Brick
 Ocean Medical Center at Meridian Health
 Clinical Trials Office - Ocean Medical Center at Meridian Health
Ph: 732-206-8384
  Hackensack
 CCOP - Northern New Jersey
 Donna McNamara
Ph: 201-996-5834
 Hackensack University Medical Center Cancer Center
 Clinical Trials Office - Hackensack University Medical Center Cancer Center
Ph: 201-996-2879
  Livingston
 St. Barnabas Medical Center Cancer Center
 Clinical Trials Office - St. Barnabas Medical Center Cancer Center
Ph: 973-322-2470
  Long Branch
 Monmouth Medical Center
 Clinical Trials Office - Monmouth Medical Center
Ph: 732-923-7689
  Marlton
 Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton
 Clinical Trials Office - Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton
Ph: 888-847-8823
  Morristown
 Carol G. Simon Cancer Center at Morristown Memorial Hospital
 Paul Heller, MD
Ph: 973-971-5900
  Neptune
 Jersey Shore Cancer Center at Jersey Shore University Medical Center
 Henry Sprance, MD, PhD
Ph: 732-776-4128
  New Brunswick
 Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School
 Clinical Trials Office - Cancer Institute of New Jersey
Ph: 732-235-8675
  Red Bank
 Booker Cancer Center at Riverview Medical Center
 Denis Fitzgerald, MD
Ph: 732-530-8666
  Ridgewood
 Valley Hospital - Ridgewood
 William Burke, MD
Ph: 734-936-6886
  Summit
 Overlook Hospital
 Paul Heller, MD
Ph: 973-971-5900
  Toms River
 J. Phillip Citta Regional Cancer Center at Community Medical Center
 Clinical Trials Office - J. Phillip Citta Regional Cancer Center at Community Medical Center
Ph: 732-818-3882
  Voorhees
 Cancer Institute of New Jersey at Cooper - Voorhees
 Clinical Trials Office - Cancer Institute of New Jersey at Cooper University Hospital - Voorhees
Ph: 856-325-6757
 Fox Chase Virtua Health Cancer Program at Virtua West Jersey
 Howard Saul, DO
Ph: 856-673-0015
New Mexico
  Albuquerque
 Southwest Gynecologic Oncology Associates, Incorporated
 Carolyn Muller, MD
Ph: 505-272-0185
 University of New Mexico Cancer Center
 Clinical Trials Office - University of New Mexico Cancer Center
Ph: 505-272-6972
New York
  Albany
 Women's Cancer Care Associates
 Thomas Morrissey
Ph: 518-458-1390
  Brightwaters
 Schwartz Gynecologic Oncology
 Benjamin Schwartz
Ph: 631-376-0055
  Bronx
 Our Lady of Mercy Medical Center Comprehensive Cancer Center
 Peter Wiernik, MD
Ph: 718-304-7200
  Brooklyn
 SUNY Downstate Medical Center
 Ovadia Abulafia, MD
Ph: 718-270-2152
  Buffalo
 Roswell Park Cancer Institute
 Clinical Trials Office - Roswell Park Cancer Institute
Ph: 877-275-7724
  East Syracuse
 CCOP - Hematology-Oncology Associates of Central New York
 Jeffrey Kirshner, MD
Ph: 315-472-7504
  Jamaica
 Queens Cancer Center of Queens Hospital
 Natalia Calderon
Ph: 718-883-4031
  Middletown
 Tucker Center for Cancer Care at Orange Regional Medical Center
 Clinical Trials Office - Tucker Center for Cancer Care at Orange Regional Medical Center
Ph: 845-342-7609
  Mount Kisco
 Northern Westchester Hospital
 Jonathan Goldberg
Ph: 914-666-1200
  New York
 Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center
 Clinical Trials Office - Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center
Ph: 212-305-8615
 Memorial Sloan-Kettering Cancer Center
 Mario Leitao, Jr.
Ph: 212-639-8895
800-525-2225
 Mount Sinai Medical Center
 Jamal Rahaman
Ph: 212-241-6500
 NYU Cancer Institute at New York University Medical Center
 Stephanie Blank, MD
Ph: 212-263-2668
  Staten Island
 Nalitt Cancer Institute at Staten Island University Hospital
 Qun Dai
Ph: 718-226-6400
  Stony Brook
 Stony Brook University Cancer Center
 Clinical Trials Office - Stony Brook University Cancer Center
Ph: 800-862-2215
  Syracuse
 SUNY Upstate Medical University Hospital
 Clinical Trials Office - SUNY Upstate Medical University Hospital
Ph: 315-464-5476
North Carolina
  Asheboro
 Randolph Hospital
 Clinical Trails Office - Randolph Hospital
Ph: 336-832-0821
  Asheville
 Hope A Women's Cancer Center
 David Hetzel, MD
Ph: 828-670-8403
  Burlington
 Alamance Cancer Center at Alamance Regional Medical Center
 Janak Choksi, MD
Ph: 336-538-7737
  Chapel Hill
 Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
 Clinical Trials Office - Lineberger Comprehensive Cancer Center
Ph: 877-668-0683; 919-966-4432
  Charlotte
 Blumenthal Cancer Center at Carolinas Medical Center
 Clinical Trials Office - Blumenthal Cancer Center at Carolinas Medical Center
Ph: 704-355-2884
 Presbyterian Cancer Center at Presbyterian Hospital
 Clinical Trials Office - Presbyterian Cancer Center at Presbyterian Hospital
Ph: 704-384-5369
  Durham
 Duke Comprehensive Cancer Center
 Clinical Trials Office - Duke Comprehensive Cancer Center
Ph: 888-275-3853
  Goldsboro
 Wayne Memorial Hospital, Incorporated
 James Atkins, MD
Ph: 919-580-0000
  Greensboro
 Moses Cone Regional Cancer Center at Wesley Long Community Hospital
 Clinical Trials Office - Moses Cone Regional Cancer Center at Wesley Long Community Hospital
Ph: 336-621-8374
  Greenville
 Gynecologic Oncology Network
 Howard Homesley, MD
Ph: 252-756-5388
  Kinston
 Kinston Medical Specialists
 Peter Watson, MD
Ph: 252-559-2200ext.201
  Pinehurst
 FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center
 Clinical Trials Office - FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center
Ph: 910-715-2200
  Reidsville
 Annie Penn Cancer Center
 Clinical Trials Office - Annie Penn Cancer Center
Ph: 336-621-8374
  Winston-Salem
 Piedmont Hematology-Oncology Associates
 Rolland Barrett, MD
Ph: 336-277-8800
 Wake Forest University Comprehensive Cancer Center
 Clinical Trials Office - Wake Forest University Comprehensive Cancer Center
Ph: 336-713-6771
North Dakota
  Bismarck
 Bismarck Cancer Center
 Edward Wos, DO
Ph: 701-323-5741
 Medcenter One Hospital Cancer Care Center
 Edward Wos, DO
Ph: 701-323-5741
 Mid Dakota Clinic, PC
 Clinical Trials Office - Mid Dakota Clinic, PC
Ph: 701-530-6950
 St. Alexius Medical Center Cancer Center
 Clinical Trials Office - St. Alexius Medical Center Cancer Center
Ph: 701-530-6950
  Fargo
 Dakota Cancer Institute at Dakota Clinic - South University
 Mahendra Gupta
Ph: 701-364-8910
800-437-4054
Ohio
  Akron
 McDowell Cancer Center at Akron General Medical Center
 Eric Jenison, MD
Ph: 330-344-6041
 Summa Center for Cancer Care at Akron City Hospital
 Clinical Trials Office - Akron City Hospital
Ph: 330-375-6101
  Bowling Green
 Wood County Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
  Canton
 Aultman Cancer Center at Aultman Hospital
 Clinical Trials Office - Aultman Cancer Center at Aultman Hospital
Ph: 330-363-6891
 Mercy Cancer Center at Mercy Medical Center
 Mitchell Haut, MD
Ph: 330-453-9993
  Cincinnati
 Charles M. Barrett Cancer Center at University Hospital
 William Richards
Ph: 806-796-1317
 Christ Hospital Cancer Center
 James Essell, MD
Ph: 513-793-6052
 Good Samaritan Hospital Cancer Treatment Center
 Jack Basil, MD
Ph: 513-872-3401
  Cleveland
 Case Comprehensive Cancer Center
 Clinical Trials Office - Case Comprehensive Cancer Center
Ph: 800-641-2422
 Cleveland Clinic Cancer Center at Fairview Hospital
 Clinical Trials Office - Cleveland Clinic Cancer Center at Fairview Hospital
Ph: 216-476-9362
 Cleveland Clinic Taussig Cancer Center
 Clinical Trials Office - Cleveland Clinic Taussig Cancer Center
Ph: 866-223-8100
 MetroHealth Cancer Care Center at MetroHealth Medical Center
 Peter Rose, MD
Ph: 216-444-1712
  Columbus
 Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center
 Clinical Trials Office - OSU Comprehensive Cancer Center
Ph: 614-293-4976
 Email: osu@emergingmed.com
 Mount Carmel Health - West Hospital
 George Lewandowski, MD
Ph: 614-224-7662
 Riverside Methodist Hospital Cancer Care
 Clinical Trials Office - Riverside Methodist Hospital Cancer Care
Ph: 614-566-4475
  Dayton
 CCOP - Dayton
 Max Clark, DO
Ph: 937-429-2410
 David L. Rike Cancer Center at Miami Valley Hospital
 Clinical Trials Office - David L. Rike Cancer Center at Miami Valley Hospital
Ph: 937-208-2079
 Good Samaritan Hospital
 Max Clark, DO
Ph: 937-429-2410
 Grandview Hospital
 Max Clark, DO
Ph: 937-429-2410
 Samaritan North Cancer Care Center
 Max Clark, DO
Ph: 937-429-2410
 Veterans Affairs Medical Center - Dayton
 Max Clark, DO
Ph: 937-429-2410
  Elyria
 Hematology Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
  Findlay
 Blanchard Valley Medical Associates
 Max Clark, DO
Ph: 937-429-2410
  Franklin
 Middletown Regional Hospital
 Max Clark, DO
Ph: 937-429-2410
  Greenville
 Wayne Hospital
 Max Clark, DO
Ph: 937-429-2410
  Kettering
 Charles F. Kettering Memorial Hospital
 Clinical Trials Office - Charles F. Kettering Memorial Hospital
Ph: 937-298-3399 ext. 57556
  Lima
 Lima Memorial Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Rita's Medical Center
 Clinical Trials Office - St. Rita's Medical Center
Ph: 419-226-9617
  Maumee
 Northwest Ohio Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Luke's Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
  Mayfield Heights
 Hillcrest Cancer Center at Hillcrest Hospital
 Peter Rose, MD
Ph: 216-444-1712
  Mentor
 Lake/University Ireland Cancer Center
 Steven Waggoner, MD
Ph: 216-844-5011
  Oregon
 St. Charles Mercy Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Clinic - Oregon
 Paul Schaefer, MD
Ph: 419-479-5605
  Salem
 Cancer Research UK Medical Oncology Unit at Churchill Hospital & Weatherall Institute of Molecular Medicine - Oxford
 Jennifer Payne
Ph: 44-1865-226-184
  Sandusky
 North Coast Cancer Care, Incorporated
 Paul Schaefer, MD
Ph: 419-479-5605
  Sylvania
 Flower Hospital Cancer Center
 Clinical Trials Office - Flower Hospital Cancer Center
Ph: 419-824-1842
  Tiffin
 Mercy Hospital of Tiffin
 Paul Schaefer, MD
Ph: 419-479-5605
  Toledo
 CCOP - Toledo Community Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 Medical University of Ohio Cancer Center
 Clinical Trials Office - Medical University of Ohio Cancer Center
Ph: 419-383-6583
 St. Anne Mercy Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Vincent Mercy Medical Center
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Clinic, Incorporated - Main Clinic
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Hospital
 Clinical Trials Office - Toledo Hospital
Ph: 419-824-1842
  Troy
 UVMC Cancer Care Center at Upper Valley Medical Center
 Clinical Trials Office - UVMC Cancer Care Center at Upper Valley Medical Center
Ph: 937-440-4842
  Wauseon
 Fulton County Health Center
 Clinical Trials Office - Fulton County Health Center
Ph: 419-330-2708
  Wilmington
 Clinton Memorial Hospital
 Max Clark, DO
Ph: 937-429-2410
  Wooster
 Cancer Treatment Center
 Clinical Trials Office - Cancer Treatment Center
Ph: 330-375-4221
  Xenia
 Ruth G. McMillan Cancer Center at Greene Memorial Hospital
 Max Clark, DO
Ph: 937-429-2410
Oklahoma
  Oklahoma City
 Oklahoma University Cancer Institute
 Robert Mannel, MD
Ph: 405-271-8787
Oregon
  Coos Bay
 Bay Area Hospital
 Bret Cook, MD
Ph: 541-267-5151
  Portland
 Kaiser Permanente Health Care - Portland
 Nagendra Tirumali, MD
Ph: 503-331-6500
 Legacy Good Samaritan Hospital & Comprehensive Cancer Center
 Clinical Trials Office - Legacy Good Samaritan Hospital & Comprehensive Cancer Center
Ph: 503-413-1742
 Northwest Cancer Specialists at Rose Quarter Cancer Center
 William Winter, III
Ph: 503-228-6509
 Oregon Health and Science University Cancer Institute
 Clinical Trials Office - Oregon Health and Science University Cancer Institute
Ph: 503-494-1080
 Email: trials@ohsu.edu
  The Dalles
 Celilo Cancer Center at Mid-Columbia Medical Center
 Samuel Taylor, MD
Ph: 514-296-7587
Pennsylvania
  Abington
 Rosenfeld Cancer Center at Abington Memorial Hospital
 Clinical Trials Office - Rosenfeld Cancer Center at Abington Memorial Hospital
Ph: 215-481-2402
  Allentown
 Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
 Richard Boulay, MD
Ph: 610-402-3650
  Ephrata
 Ephrata Cancer Center at Ephrata Community Hospital
 Norman Rosenblum, MD, PhD
Ph: 215-955-6200
  Hershey
 Penn State Cancer Institute at Milton S. Hershey Medical Center
 Clinical Trials Office - Penn State Cancer Institute at Milton S. Hershey Medical Center
Ph: 717-531-3779
 Email: CTO@hmc.psu.edu
  Media
 Riddle Memorial Hospital Cancer Center
 Norman Rosenblum, MD, PhD
Ph: 215-955-6200
  Philadelphia
 Abramson Cancer Center of the University of Pennsylvania
 Clinical Trials Office - Abramson Cancer Center of the University of Pennsylvania
Ph: 800-474-9892
 Chestnut Hill Healthcare Cancer Center
 Frederick Fellin, MD
Ph: 215-955-6039
 Fox Chase Cancer Center - Philadelphia
 Clinical Trials Office - Fox Chase Cancer Center - Philadelphia
Ph: 215-728-4790
 Joan Karnell Cancer Center at Pennsylvania Hospital
 Patricia Ford, MD
Ph: 215-829-6088
 Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
 Clinical Trials Office - Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
Ph: 215-955-6084
  Pittsburgh
 UPMC Cancer Center at Magee-Womens Hospital
 Clinical Trials Office - UPMC Cancer Center at Magee-Womens Hospital
Ph: 412-647-2811
 Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital
 Eileen Segreti, MD
Ph: 412-578-1116
  Reading
 McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center
 Clinical Trials Office - McGlinn Family Regional Cancer Center
Ph: 610-988-9323
  Scranton
 Hematology and Oncology Associates of Northeastern Pennsylvania
 Martin Hyzinski, MD
Ph: 570-558-3020
 Norman Rosenblum, MD, PhD
Ph: 215-955-6200
 Mercy Hospital Cancer Center - Scranton
 Martin Hyzinski, MD
Ph: 570-558-3020
  York
 York Cancer Center at Apple Hill Medical Center
 Timothy McGuinness, DO
Ph: 717-851-6120
 Timothy McGuinness, DO
Ph: 717-851-6120
Rhode Island
  Providence
 Women and Infants Hospital of Rhode Island
 Clinical Trials Office - Women and Infants Hospital of Rhode Island
Ph: 401-274-1122
South Carolina
  Charleston
 Hollings Cancer Center at Medical University of South Carolina
 Clinical Trials Office - Hollings Cancer Center at Medical University of South Carolina
Ph: 843-792-9321
South Dakota
  Rapid City
 Black Hills Obstetrics & Gynecology LLP
 Helen Frederickson, MD
Ph: 605-343-9224
  Sioux Falls
 Sanford Cancer Center at Sanford USD Medical Center
 Clinical Trials Office - Sanford Cancer Center
Ph: 605-328-1367
Tennessee
  Chattanooga
 Chattanooga's Program in Women's Oncology
 Stephen DePasquale
Ph: 423-266-3636
  Johnson City
 East Tennessee State University Cancer Center at Johnson City Medical Center
 Clinical Trials Office - East Tennessee State University Cancer Center at Johnson City Medical Center
Ph: 423-433-6210
  Kingsport
 Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center
 Clinical Trials Office - Christine LaGuardia Phillips Cancer Center
Ph: 423-224-5593
  Knoxville
 Hall and Martin, M.Ds., PC
 David Martin
Ph: 865-971-4992
  Memphis
 Baptist Centers for Cancer Care
 Clinical Trials Office - Baptist Centers for Cancer Care
Ph: 901-226-3077
 University of Tennessee College of Medicine
 Clinical Trials Office - University of Tennessee College of Medicine
Ph: 901-516-2212
  Nashville
 MBCCOP - Meharry Medical College - Nashville
 Steven Wolff, MD
Ph: 615-327-6277
 Vanderbilt-Ingram Cancer Center
 Clinical Trials Office - Vanderbilt-Ingram Cancer Center
Ph: 1-800-811-8480;
Texas
  Amarillo
 Harrington Cancer Center
 Clinical Trials Officec - Harrington Cancer Center
Ph: 806-359-4673
 Email: ryokubaitis@harringtoncc.org
  Houston
 M. D. Anderson Cancer Center at University of Texas
 Clinical Trials Office - M. D. Anderson Cancer Center at the University of Texas
Ph: 713-792-3245
  Lubbock
 UMC Southwest Cancer and Research Center
 Clinical Trials Office - UMC Southwest Cancer and Research Center
Ph: 806-775-8590
  Temple
 CCOP - Scott and White Hospital
 Charles Capen, MD
Ph: 254-724-2576
Utah
  American Fork
 American Fork Hospital
 Ross Morgan, MD
Ph: 801-408-5757
  Cedar City
 Sandra L. Maxwell Cancer Center
 Ross Morgan, MD
Ph: 801-408-5757
  Murray
 Jon and Karen Huntsman Cancer Center at Intermountain Medical Center
 Ross Morgan, MD
Ph: 801-408-5757
  Ogden
 Val and Ann Browning Cancer Center at McKay-Dee Hospital Center
 Clinical Trials Office - McKay-Dee Hospital Center
Ph: 801 387-7426
  Provo
 Utah Valley Regional Medical Center - Provo
 Clinical Trials Office - Utah Valley Regional Medical Center - Provo
Ph: 801-357-7965
  Saint George
 Dixie Regional Medical Center - East Campus
 Clinical Trials Office - Dixie Regional Medical Center - East Campus
Ph: 435-688-4167
  Salt Lake City
 Huntsman Cancer Institute at University of Utah
 Clinical Trials Office - Huntsman Cancer Institute at University of Utah
Ph: 801-581-4477
 Email: clinical.trials@hci.utah.edu
 LDS Hospital
 Ross Morgan, MD
Ph: 801-408-5757
 Utah Cancer Specialists at UCS Cancer Center
 Ross Morgan, MD
Ph: 801-408-5757
Vermont
  Burlington
 Fletcher Allen Health Care - University Health Center Campus
 Clinical Trials Office - Fletcher Allen Health Care
Ph: 802-656-8990
Virginia
  Annandale
 Northern Virginia Pelvic Surgery Associates
 John Elkas
Ph: 202-782-8513
  Charlottesville
 University of Virginia Cancer Center
 Susan Modesitt
Ph: 434-924-9333
800-223-9173
  Danville
 Danville Regional Medical Center
 Clinical Trials Office - Danville Regional Medical Center
Ph: 434-799-3753
  Fairfax
 Kaiser Permanente Medical Center - Fair Oaks
 Leon Hwang, MD
Ph: 301-548-5768
  Fredericksburg
 Fredericksburg Oncology, Incorporated
 Paul Schaefer, MD
Ph: 419-479-5605
  Gloucester
 Riverside Middle Peninsula Cancer Center
 William Irvin, MD
Ph: 434-924-5197
  Newport News
 Peninsula Cancer Institute - Newport News Office
 William Irvin, MD
Ph: 434-924-5197
  Norfolk
 Virginia Oncology Associates - Lake Wright
 Robert Squatrito, MD
Ph: 757-466-1466
  Norton
 Southwest Virginia Regional Cancer Center at Wellmonth Health
 Malcolm Mathews, MD
Ph: 423-224-3150
  Richmond
 Bon Secours Cancer Institute at St. Mary's Hospital
 Charles Welander, MD
Ph: 804-288-8900
 Virginia Commonwealth University Massey Cancer Center
 Clinical Trials Office -Virginia Commonwealth University Massey Cancer Center
Ph: 804-628-1939
  Roanoke
 Carilion Gynecologic Oncology Associates
 Dennis Scribner, MD
Ph: 540-345-8574
  Williamsburg
 Peninsula Cancer Institute - Williamsburg Office
 William Irvin, MD
Ph: 434-924-5197
Washington
  Seattle
 CCOP - Virginia Mason Research Center
 Thomas Malpass
Ph: 206-341-0446
 Fred Hutchinson Cancer Research Center
 Benjamin Greer, MD
Ph: 206-685-2463
 University Cancer Center at University of Washington Medical Center
 Clinical Trials Office - University Cancer Center at University of Washington Medical Center
Ph: 206-616-8289
  Tacoma
 Madigan Army Medical Center - Tacoma
 David E. McCune, MD
Ph: 253-968-2505
 Northwest Medical Specialties, PLLC - Tacoma
 Benjamin Greer, MD
Ph: 206-685-2463
West Virginia
  Huntington
 Edwards Comprehensive Cancer Center at Cabell Huntington Hospital
 Oncology Research Supervisor
Ph: 304-399-6617
Wisconsin
  Eau Claire
 Center for Cancer Treatment & Prevention at Sacred Heart Hospital
 Stuart Tipping, MD
Ph: 715-389-7549
 Marshfield Clinic Cancer Care at Regional Cancer Center
 Stuart Tipping, MD
Ph: 715-389-7549
  Elkhorn
 Vince Lombardi Cancer Center at Aurora Lakeland Medical Center - Elkhorn
 Rossana Madamba
Ph: 262-741-2671
800-252-2990
  Glendale
 Oncology Alliance, SC - Milwaukee - East
 Clinical Trials Office - Oncology Alliance, SC - Milwaukee - East
Ph: 414-906-4480
  Green Bay
 Green Bay Oncology, Limited at St. Mary's Hospital
 Jonathan Tammela
Ph: 920-884-3135
 Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
 Jonathan Tammela
Ph: 920-432-6049
 St. Mary's Hospital Medical Center - Green Bay
 Jonathan Tammela
Ph: 920-498-4200
 St. Vincent Hospital Regional Cancer Center
 Clinical Trials Office - St. Vincent Hospital Regional Cancer Center
Ph: 920-433-8889
 Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center
 Clinical Trials Office - Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center
Ph: 414-649-5717
  La Crosse
 Gundersen Lutheran Center for Cancer and Blood
 Clinical Trials Office - Gundersen Lutheran Cancer Center
Ph: 608-775-2385
 Email: cancerctr@gundluth.org
  Madison
 Dean Medical Center - Madison
 Charles Diggs, MD
Ph: 608-410-2746
 University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
 Clinical Trials Office - University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
Ph: 608-262-5223
  Manitowoc
 Holy Family Memorial Medical Center Cancer Care Center
 Clinical Trials Office - Holy Family Memorial Medical Center Cancer Care Center
Ph: 920-320-2749
  Marinette
 Bay Area Cancer Care Center at Bay Area Medical Center
 Jonathan Tammela
Ph: 715-735-6523
888-788-2070
  Marshfield
 Marshfield Clinic - Marshfield Center
 Clinical Trials Office - Marshfield Clinic - Marshfield Center
Ph: 800-782-1581 ext. 94457
 Saint Joseph's Hospital
 Stuart Tipping, MD
Ph: 715-389-7549
  Milwaukee
 Froedtert Hospital and Medical College of Wisconsin
 Clinical Trials Office - Froedtert Hospital
Ph: 414-805-3666
 Medical College of Wisconsin Cancer Center
 Clinical Trials Office - Medical College of Wisconsin Cancer Center
Ph: 414-805-4380
 Medical Consultants, Limited
 Peter Johnson, MD(Contact information may not be current)
Ph: 262-549-6662
 Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center
 Clinical Trials Office - Vince Lombardi Cancer Clinic
Ph: 414-649-5717
 Wheaton Franciscan Cancer Care - St. Joseph
 Norwood Anderson, MD
Ph: 414-874-1100
  Minocqua
 Marshfield Clinic - Lakeland Center
 Stuart Tipping, MD
Ph: 715-389-7549
  Oconomowoc
 Regional Cancer Center at Oconomowoc Memorial Hospital
 Clinical Trials Office - Regional Cancer Center at Oconomowoc Memorial Hospital
Ph: 262-928-7878
  Oconto Falls
 Green Bay Oncology, Limited - Oconto Falls
 Jonathan Tammela
Ph: 920-846-3444
800-432-6049
  Oshkosh
 Vince Lombardi Cancer Clinic - Oshkosh
 Zahid Dar
Ph: 920-303-8700
  Rhinelander
 Ministry Medical Group at Saint Mary's Hospital
 Stuart Tipping, MD
Ph: 715-389-7549
  Rice Lake
 Marshfield Clinic - Indianhead Center
 Stuart Tipping, MD
Ph: 715-389-7549
  Sheboygan
 Vince Lombardi Cancer Clinic - Sheboygan
 Clinical Trials Office - Vince Lombardi Cancer Clinic - Sheboygan
Ph: 414-649-7200
  Slinger
 Vince Lombard Cancer Clinic at Aurora Health Center - Slinger
 Peter Johnson, MD(Contact information may not be current)
Ph: 262-549-6662
  Stevens Point
 Saint Michael's Hospital Cancer Center
 Stuart Tipping, MD
Ph: 715-389-7549
  Sturgeon Bay
 Green Bay Oncology, Limited - Sturgeon Bay
 Jonathan Tammela
Ph: 800-432-6049
  Two Rivers
 Vince Lombardi Cancer Clinic - Two Rivers
 Andrew Yetter
Ph: 920-793-6000
  Waukesha
 Waukesha Memorial Hospital Regional Cancer Center
 Clinical Trials Office - Waukesha Memorial Hospital Regional Cancer Center
Ph: 262-928-7632
  West Allis
 Aurora Women's Pavilion of West Allis Memorial Hospital
 Peter Johnson, MD(Contact information may not be current)
Ph: 262-549-6662
  Weston
 Marshfield Clinic - Weston Center
 Stuart Tipping, MD
Ph: 715-389-7549
  Wisconsin Rapids
 Marshfield Clinic - Wisconsin Rapids Center
 Stuart Tipping, MD
Ph: 715-389-7549
Canada
Ontario
  Toronto
 Edmond Odette Cancer Centre at Sunnybrook
 Allan Covens, MD
Ph: 416-480-4026
Japan
  Kagoshima City, Kagoshima
 Kagoshima City Hospital
 Masayuki Hatae, MD
Ph: 81-99-224-2101
  Kure
 National Hospital Organization - Medical Center of Kure
 Kazuhiro Takehara
Ph: 81-82-322-3111
  Matsuyama
 Shikoku Cancer Center
 Masamichi Hiura, MD
Ph: 81-89-999-1111
  Saitama
 Saitama Medical University International Medical Center
 Keiichi Fujiwara, MD, PhD
Ph: 81-42-984-4637
  Sendai
 Tohoku University Graduate School of Medicine
 Tadao Takano, MD
Ph: 81-22-717-7254
  Shinjuku-ku
 Keio University School of Medicine
 Daisuke Aoki
Ph: 81-3-3353-1211
  Tokyo
 National Cancer Center Hospital
 Noriyuki Katsumata, MD
Ph: 81-3-3542-2511
  Tottori
 Tottori University Hospital
 Junzo Kigawa, MD, PhD
Ph: 81-859-33-1111
Iwate
  Morioka
 Iwate Medical University Hospital
 Toru Sugiyama
Ph: 81-19-651-5111
Republic of Korea
  Seoul
 Asan Medical Center - University of Ulsan College of Medicine
 Joo-Hyun Nam
Ph: 82-2-224-3210
 Seoul National University Hospital
 Soon-Beom Kang
Ph: 82-2-763-5110
 Yongdong Severance Hospital
 Jae-Hoon Kim
Ph: 82-23-497-3482
  Suwon
 Ajou University Hospital
 Hee-Sug Ryu

Related Information

Featured trial article

Registry Information
Official Title A Phase III Trial of Carboplatin and Paclitaxel Plus Placebo Versus Carboplatin and Paclitaxel Plus Concurrent Bevacizumab (NSC # 704865, IND #7921) Followed By Placebo, Versus Carboplatin and Paclitaxel Plus Concurrent and Extended Bevacizumab, in Women With Newly Diagnosed, Previously Untreated, Suboptimal Advanced Stage Epithelial Ovarian, Primary Peritoneal Cancer, or Fallopian Tube Cancer
Trial Start Date 2005-09-26
Trial Completion Date 2008-10-11 (estimated)
Registered in ClinicalTrials.gov NCT00262847
Date Submitted to PDQ 2005-11-01
Information Last Verified 2009-02-13
NCI Grant/Contract Number CA27469

Note: The purpose of most clinical trials listed in this database is to test new cancer treatments, or new methods of diagnosing, screening, or preventing cancer. Because all potentially harmful side effects are not known before a trial is conducted, dose and schedule modifications may be required for participants if they develop side effects from the treatment or test. The therapy or test described in this clinical trial is intended for use by clinical oncologists in carefully structured settings, and may not prove to be more effective than standard treatment. A responsible investigator associated with this clinical trial should be consulted before using this protocol.

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