CHAPTER 22 INDEXING PRINCIPLES FOR CATEGORY B (ORGANISMS) Category B is a collection of MeSH terms largely for those animals, organisms and plants of medical importance. Covered are many vertebrates, invertebrates, bacteria, viruses, algae, fungi, and plants and archaea. Living organisms can be grouped into three domains - Archaea, Bacteria, and Eukarya. Prior to 1998, the Archaea, which were called Archaeobacteria, were grouped under the bacteria. Now they are considered a separate domain of life. In 1998, they were removed from the Bacteria tree (B3) and placed in a new tree - Archaea (B7). The Eukarya occupy categories B1, B2, B5 and B6. The viruses are in category B4. 22.1 The following subheadings are assigned to Category B; however many of the subheadings are permitted only with certain subcategories of Category B organisms. /abnormalities /anatomy & histology /blood /cerebrospinal fluid /chemistry /classification /cytology /drug effects /embryology /enzymology /genetics /growth & development /immunology /injuries /isolation & purification /metabolism /microbiology /parasitology /pathogenicity /physiology /psychology /radiation effects /surgery /ultrastructure /urine /virology 22.2 The following is a breakdown of permissible subheadings by tree: B1 - Invertebrates /anatomy & histology /chemistry /classification /cytology /drug effects /embryology /enzymology /genetics /growth & development /immunology /isolation & purification /metabolism /microbiology /parasitology /pathogenicity /physiology /radiation effects /ultrastructure /virology B2 - Vertebrates /abnormalities /anatomy & histology /blood /cerebrospinal fluid /classification /embryology /genetics /growth & development /immunology /injuries /metabolism /microbiology /parasitology /physiology /psychology (mammals only) /surgery /urine /virology B3 - Bacteria /chemistry /classification /cytology /drug effects /enzymology /genetics /growth & development /isolation & purification /metabolism /pathogenicity /physiology /radiation effects /ultrastructure /virology B4 - Viruses Same subheadings as B3 except /cytology and /virology are not permitted B5 - Fungi Same subheadings as B3 B6 - Plants /anatomy & histology /chemistry /classification /cytology /drug effects /embryology /enzymology /genetics /growth & development /immunology /metabolism /microbiology /parasitology /physiology /radiation effects /ultrastructure /virology B7 - Archaea Same subheadings as B3 22.3 Index the structure of microorganisms, with the exception of viruses, under the name of the organism with the subheading /cytology (IM). /ultrastructure is available for the structure of subcellular elements. 22.3.1 Index the structure of viruses with the subheading /ultrastructure. 22.4 Index the taxonomy of organisms under the Category B term with the subheading /classification. 22.5 Index the life cycle or life history of a lower organism under the name of the organism with the subheading /growth and development. METAMORPHOSIS, BIOLOGICAL is available as a coordinate for organisms undergoing this process, for example, insects and frogs. Since it is usually the point of the article, it is usually made IM. 22.6 Index the chemistry or the chemical composition of an organism or any aspect of its chemical structure under the name of the organism with the subheading /chemistry (IM) and the specific chemical component with the appropriate subheading, usually /anal (IM). Characterization of pneumococcal glycolipids. PNEUMOCOCCUS / *chem GLYCOLIPIDS /*anal If a cytological structure of an organism is being specifically discussed, this may be indexed also with /chemistry, but this combination will probably be (NIM). Glycine composition of the staphylococcal cell wall. STAPHYLOCOCCUS /*chem /ultrastruct GLYCINE / * anal CELL WALL /chem The subheading /chemistry is not permitted with Category B2 (Vertebrates) because the point of a study would be the chemistry of an organ in an animal rather than the chemistry of the entire animal (see 21.18). The content of sodium in the liver of the dog. *DOGS SODIUM / * anal LIVER / * chem ANIMAL (check tag) 22.7 Index the effect of a drug on an organism under the name of the organism with the subheading /drug effects (IM) and the name of the drug with the subheading /pharmacology (IM). Also index the specific aspect of the organism such as its structure, physiology, or metabolism affected by the drug, probably NIM. Effect of streptomycin on Escherichia coli. STREPTOMYCIN / * pharmacol ESCHERICHIA COLI / * drug eff Effect of streptomycin on the metabolism of ribosomal proteins in Escherichia coli. STREPTOMYCIN / * pharmacol ESCHERICHIA COLI / * drug eff / metab RIBOSOMAL PROTEINS / * metab BACTERIAL PROTEINS / * metab 22.7.1 The subheading /drug effects is not permitted with Category B2 terms. As with /chemistry, the effect of the drug is on a particular organ of the animal rather than on the whole animal. Effect of potassium on the dog heart. POTASSIUM / * pharmacol HEART / * drug eff *DOGS ANIMAL (check tag) 22.8 Index the effect of radiation on organisms under the name of the organism with the subheading /radiation effects (IM) and add the specific radiation if given (IM). Do not, however; add RADIATION, IONIZING or RADIATION, NON-IONIZING, or X-RAYS; see section 19.8.60. Effect of ultraviolet light on DNA synthesis in Escherichia coli. ESCHERICHIA COLI / * rad eff / genet DNA, BACTERIAL / * rad eff / biosyn *ULTRAVIOLET RAYS 22.9 The subheading /microbiology is used in studies with bacteria, viruses, and fungi or archaea. The subheading /parasitology is used in studies with Category B1 organisms, the invertebrates. A study of microorganisms in the lung. LUNG / *microbiol Arthropod parasites of domestic animals. *ARTHROPODS ANIMALS, DOMESTIC / * parasitol ANIMAL (check tag) 22.10 The subheading /isolation & purification is used when a microorganism, protozoan, or helminth is isolated, or when its presence is demonstrated by immunologic or genetic techniques (see sections 19.8.41, 19.10.3 and 19.10.6). Demonstration of bronchial Aerobacter. BRONCHI / * microbiol AEROBACTER / * isol Demonstration of Cryptosporidium in the liver. CRYPTOSPORIDIUM / * isol LIVER / * parasitol ANIMAL (check tag) Detection of HIV-1 in the lung by analysis of its DNA. HIV-1 / * isol LUNG / * virol DNA, VIRAL / * anal (HIV-1 / genet may be added if the DNA is discussed in addition to just discussing the presence of the virus.) 22.11 Do not equate the presence of a microbe or parasite in an organ or tissue with infection. A study may be about the presence of an organism in an organ, or its isolation from an organ, without being about a disease caused by that organism. Index an infection term only when the author indicates an infection. Isolation of Staphylococcus from human skin. SKIN / * microbiol STAPHYLOCOCCUS / * isol HUMAN (check tag) (Not STAPHYLOCOCCAL INFECTIONS and SKIN DISEASES, BACTERIAL) 22.11.1 Infected cell lines or cultured cells are frequently used in preclinical research to study various aspects of a microbe or parasite. Index these infected cells under the organism with an appropriate subheading and the specific cell with /microbiology, /parasitology or / virology and not under an infection term. Latent infection of 3T3 cells with herpes simplex virus. 3T3 cells HERPES SIMPLEX VIRUS / * physiol ANIMAL (check tag) MICE (check tag) Infection of cultured macrophages by Trypanosoma cruzi. CELLS, CULTURED MACROPHAGES / *parasitol TRYPANOSOMA CRUZI / * physiol ANIMAL (check tag) Occasionally an infected cell line or cultured cell may be studied as a model for a disease. In this case, index the appropriate infection term. Viral growth in a human cell line model of hepatitis B. HEPATITIS B VIRUS / * growth HEPATITIS B / * virol CELL LINE HUMAN (check tag) 22.12 Many infections or infestations exist in MeSH as main headings. There are so many that the infection terms are divided into Categories C1 (bacterial and fungal infections), C2 (viral infections) and C3 (parasitic diseases). See sections 23.12 to 23.13.2. Infections frequently appear in the literature in a disguised form that may present a problem for the indexer. For example, Rickettsia tsutsugamushi infection = SCRUB TYPHUS, Bordetella pertussis infection = WHOOPING COUGH, Plasmodium infection = MALARIA, etc. MeSH contains many such equations as entry terms. In addition, under the organism heading, MeSH is annotated with the heading to be used for an infection caused by that organism. Always check MeSH before indexing an organism- infection concept as outlined in the following sections. 22.13 Index an infection with the most specific MeSH term. If an organism is the cause of a disease, always index the disease term if it is a MeSH heading. Index streptococcal infections as STREPTOCOCCAL INFECTIONS, not as STREPTOCOCCUS + INFECTION nor as STREPTOCOCCUS + BACTERIAL INFECTIONS. 22.14 In diseases attributable to a single organism by definition, whether the MeSH term is a genus or genus-species heading, index only the name of the disease and not the organism unless the organism is substantively discussed. Index TUBERCULOSIS but not MYCOBACTERIUM TUBERCULOSIS, since MeSH is annotated at the organism that "infection = TUBERCULOSIS". If, however, both the disease and the organism are discussed, both should be indexed. 22.15 When indexing an organism-infection heading, if the article names a specific species for which there is also a MeSH heading, index both the disease (IM) and the specific genus-species term (IM). Streptococcus pyogenes infections. *STREPTOCOCCAL INFECTIONS *STREPTOCOCCUS PYOGENES 22.16 If an organism causes an infection which does not exist in MeSH as a "disguised" disease (see 22.12) or as a pre-coordinated organism-infection heading, index the name of the organism (IM) and the pre-coordinated disease from Category C1, C2, or C3 which corresponds to the next more general group to which the organism belongs. MeSH does not have the term "Capillaria infections" but CAPILLARIA can be found in Category B1 under TRICHUROIDEA. There is no MeSH term for "Trichuroidea infections," but TRICHUROIDEA is indented under ENOPLIDA, for which there is the pre-coordinated disease term ENOPLIDA INFECTIONS. Capillaria Infection. *ENOPLIDA INFECTIONS *CAPILLARIA ANIMAL (check tag) The Annotated MeSH contains direct instructions for indexing Capillaria infections in the annotation at the term CAPILLARIA. Most organisms are annotated in this manner, so it is not usually necessary for the indexer to go through the above process to determine the correct infection term. 22.17 Many virus headings contain the name of a disease (for example, CHICKEN ANEMIA VIRUS and VESICULAR EXANTHEMA OF SWINE VIRUS). In many cases MeSH has a corresponding disease term for the infection caused by the virus (VESICULAR EXANTHEMA OF SWINE). In some cases, however, there is no term for the disease, only for the virus. In these cases, to index the infection caused by the virus, follow the rule given in 22.16; do not add the clinical disease term implied by the name of the virus unless the disease is actually discussed. Avian infectious bronchitis virus infection in poultry. *INFECTIOUS BRONCHITIS VIRUS, AVIAN CORONAVIRUS INFECTIONS / * vet *POULTRY DISEASES (not BRONCHITIS / * vet unless bronchitis is discussed) POULTRY ANIMAL (check tag) 22.18 MeSH has very wide coverage of bacteria and viruses, so it is seldom necessary to use reference books such as Bergey's Manual of Systematic Bacteriology or the Classification and Nomenclature of Viruses: Sixth Report of the International Committee on Taxonomy of Viruses to index an organism or its infection.To index an organism or its infection that is not a MeSH term, follow these steps. Identify the next higher taxonomic group to which the organism belongs from data in the article or in available tools. (Dorland's Illustrated Medical Dictionary, the two reference books listed above, or any other reference listed in the Bibliography at the beginning of the Annotated MeSH are official references). Check the Annotated MeSH to see whether that group exists as a main heading. If it does not, go to the next higher taxonomic level, and so on. Upon locating the MeSH heading in Category B, determine if there is a MeSH term for an infection caused by that organism or group. If there is, use only that term. If there is no MeSH heading for an infection caused by that organism or group, index the organism (IM) and add the infection for the next higher taxonomic group (IM). Gastrodiscus infection Gastrodiscus is not a MeSH heading, but the organism can be identified in a reference book as belonging to the family Paramphistomatidae. The corresponding infection term in Category C3 is TREMATODE INFECTIONS; therefore, index Gastrodiscus infection under *TREMATODE INFECTIONS *PARAMPHISTOMATIDAE ANIMAL (check tag) 22.19 Do not index infections for which no MeSH term exists under the name of the organism with the subheading /pathogenicity. As defined by MeSH, /pathogenicity is to be used for studies of the ability of an organism to produce a disease, not for the fact or presence of an infection. 22.19.1 To use /pathogenicity correctly, the research must be concerned with questions such as "How pathogenic is this microbe for one animal but not another?", "How pathogenic is this organism for man?", "Is this microbe virulent?", etc. See Section 19.8.51 for a further discussion of the correct use of the subheading. When the indexer determines the article to be on the fact or presence of an infection, the indexer must disqualify /pathogenicity as a concept unless the author also discusses the virulence or pathogenicity of the organism in the infection. 22.19.2 In an article determining or discussing the pathogenicity of an organism in vitro, the subheading /pathogenicity may be used with reference to tissue or cells cultured in vitro. This subheading is not restricted to in vivo studies in man or animals. 22.20 The presence of a parasite in a host does not necessarily mean that a disease heading is required. Distinguish between the infestation of lower animals by parasites and the clinical human or clinical and experimental animal disease represented by Category C headings. Snails infected with schistosomes. SNAILS / * parasitol *SCHISTOSOMA (not SCHISTOSOMIASIS) ANIMAL (check tag) Bacterial infections of crabs. CRABS / * microbiol *BACTERIA (not BACTERIAL INFECTIONS) ANIMAL (check tag) 22.21 Index the host-parasite relationship under the name of the host with the subheading /parasitology (IM), the parasite with its appropriate subheading - probably /physiology (IM) and HOST-PARASITE RELATIONS (NIM). 22.22 The transmission of an organism from one host to another is not readily handled with current MeSH terminology. /transmission is available, but it is permitted only with Category C for the transmission of disease. In general, index the transmission of an organism from one host to another under the organism with the subheading /physiology. Coordinate with DISEASE VECTORS or one of the specifics treed under it and/or DISEASE RESERVOIRS if appropriate. Transmission of trypanosomes to the tsetse fly vector. TRYPANOSOMA / * physiol TSETSE FLY / * parasitol INSECT VECTORS / * parasitol ANIMAL (check tag) 22.23 When the geographic locality in which a host or a microorganism or parasite is found is significant, in addition to indexing under the host and organism, index also under the geographic heading from Category Z. It is not necessary to seek out a geographical locale routinely. Index only if it is discussed. 22.24 MeSH has very wide coverage of the viruses, particularly the vertebrate viruses. Index viruses under the specific virus term in MeSH. 22.24.1 Index a virus not in MeSH under the virus group as identified from the text or from Classification and Nomenclature of Viruses: Sixth Report of the International Committee on Taxonomy of Viruses or other reference tools. The principle to be applied in determining the correct heading is that given in 22.17 and 22.18. 22.24.2 If the host of a virus is discussed in the article, index under the virus (IM) and the host (IM or NIM depending upon the point of the article.) The genome of the green monkey retrovirus. RETROVIRIDAE / * genet *GENOME, VIRAL MONKEY, GREEN (see CERCOPITHECUS AETHIOPS) / virol ANIMAL (check tag) 22.24.3 Index bacterial viruses (bacteriophages) as BACTERIOPHAGES (IM) and the name of the bacterium (NIM). MeSH has headings for groups of phages (e.g. COLIPHAGES) as well as many specific strains (e.g., BACTERIOPHAGE M13). Index under the most specific phage term. Characterization of Bacillus subtilis phages. *BACILLUS PHAGES BACILLUS SUBTILIS / virol Mechanism of the inactivating effect of immune sera on the typhoid phage. SALMONELLA PHAGES / * immunol *IMMUNE SERA SALMONELLA TYPHI Transport in bacteriophage P22-infected Salmonella typhimurium. BACTERIOPHAGE P22 / * physiol SALMONELLA TYPHIMURIUM / * metab /virol BIOLOGICAL TRANSPORT (Note that in this example SALMONELLA TYPHIMURIUM is IM.) 22.24.4 Phage typing, BACTERIOPHAGE TYPING, is handled in a manner the reverse of 22.24.3 above. With phages, the emphasis is on the phage, the virus, and not on the bacterium it is attacking. Phage typing is a laboratory technique used to identify or classify the bacterium, and the emphasis is on the bacterium. In the first case we IM the virus and NIM the bacterium; in the other, we IM the bacterium and NIM the virus if it is indexed at all. In general, index phage typing under the bacterium with the subheading /classification (IM) and BACTERIOPHAGE TYPING (IM). Do not index under BACTERIOPHAGES for the phage or under one of the pre-coordinated phages (e.g. COLIPHAGES) unless the strain or the phage or its identity is particularly discussed. In this case the phage term will be NIM. Phage typing of staphylococci from milk. MILK / *microbiol STAPHYLOCOCCUS / *class *BACTERIOPHAGE TYPING (Do not index under STAPHYLOCOCCUS PHAGES unless the phage itself is significant and then index probably as NIM.) 22.25 Index animal, plant and microbial genetics under the name of the animal, plant or microbe with the subheading /genetics (IM). If a specific genetic concept is to be indexed, coordinate the organism /genetics (IM) with the genetic concept (IM). See also section 28.37 to 28.37.6. Recombination in Bacillus subtilis. BACILLUS SUBTILIS / * genet *RECOMBINATION, GENETIC The structural gene for alcohol dehydrogenase in Drosophila melanogaster. ALCOHOL DEHYDROGENASE / * genet DROSOPHILA MELANOGASTER / * genet *GENES, STRUCTURAL, INSECT ANIMAL (check tag) 22.26 The microbial or animal source of tissue, cellular elements, hormones, enzymes and other biological matter is almost always indexed NIM if it is indexed at all under the rules governing third-tier indexing. If the point of the research is the identity of the species or if the animal is named in the title, it should be indexed usually NIM but IM if it is a main point. This rule refers to most articles in experimental research of this nature. When indexing to cover the animal source, be sure to check the tag ANIMAL also. See section 18.7.2 for the use of the ANIMAL tag. See also sections 21.57 and 22.26.1. Bat salivary gland virus. BATS / virol *SALIVARY GLAND VIRUSES ANIMAL (check tag) Isolation of bat salivary gland virus from bats in the United States. BATS / * virol SALIVARY GLAND VIRUSES / * isol UNITED STATES ANIMAL (check tag) (here the bat is a main point and is IM) The chemistry of cat insulin in comparison with human insulin. INSULIN / * chem *CATS HUMAN (check tag) COMPARATIVE STUDY (check tag) ANIMAL (check tag) SPECIES SPECIFICITY Duplication of single-stranded DNA catalyzed by calf thymus DNA polymerase. DNA, SINGLE-STRANDED / * biosyn DNA POLYMERASES / * metab CATTLE (check tag) ANIMAL (check tag) 22.26.1 In cell-line and tissue culture studies, check the tag HUMAN or ANIMAL if this can be determined from the article, and for animals, index the animal NIM if it is not the point of the article. If, however, the identity of the animal and organ are significant, they will be indexed IM. Description of a new rat macrophage cell line. *RATS MACROPHAGES /* cytol *CELL LINE ANIMAL (check tag) The effect of dactinomycin on cell division. (the materials and methods says the study was done in a rat cell line) DACTINOMYCIN / * pharmacol CELL LINE RATS ( check tag) CELL DIVISION / * drug eff ANIMAL (check tag) 22.26.2 In many immunology studies, one animal is the experimental subject and another is the source of immunologic substance or tissue. When two or more such animals figure in an article, index each animal with or without the subheading /immunology depending on the slant of the article. See section 19.8.37. 22.27 Category B organisms used in biological assays are indexed IM or NIM depending on the tenor of the study. Biological assay of vitamin B12 using Lactobacillus leichmannii. VITAMIN B12 / * anal LACTOBACILLUS / * metab BIOLOGICAL ASSAY (IM or NIM depending upon the discussion of its method of performance). Biological assay of prostaglandins using the rat uterus. PROSTAGLANDINS / * anal / pharmacol UTERUS / * drug eff RATS (check tag) ANIMAL (check tag) BIOLOGICAL ASSAY (IM or NIM) FEMALE (check tag) 22.28 Although PRIMATES is a main heading in MeSH, we seldom encounter general articles written on primates; most articles are written on man as the check tag HUMAN. We also see two specific groups of primates, apes (APES see PONGIDAE) and monkeys (MONKEYS see HAPLORHINI) more frequently than PRIMATES in general. 22.28.1 Index under HOMINIDAE taxonomic or paleontologic man as an animal. When indexing man as a primate or anthropoid, check the tag HUMAN; when indexing all other PRIMATES, check ANIMAL. 28.28.2 Be careful with the word "singe" in French and "Affe" in German articles. These words can mean either "ape" or "monkey." 22.29 Poultry is defined by Webster as BIRDS "that serve as a source of eggs or meat" and that are commercially important. The indentions under POULTRY in MeSH meet these definitions. There should be little difficulty in indexing an article under BIRDS or POULTRY for those which are not specifically identified as CHICKENS, DUCKS, GEESE, or TURKEYS. A "bird" in an agricultural or poultry science journal is likely to be indexed under POULTRY with the disease indexed under POULTRY DISEASES. A "bird" in a forest, zoo, park, or pet shop or referred to as "wild" will be indexed as BIRDS with the disease indexed under BIRD DISEASES. If a specific MeSH heading is available, use it. For example, index an article on quail as QUAIL or the specifics COTURNIX or COLINUS if indicated rather than the more general term POULTRY or BIRDS. 22.30 Plants figure in INDEX MEDICUS articles as food, the source of drugs, as medicines themselves, as commercial products, and as types of tissue in biophysical, biochemical, and biotechnologic studies. Category B6 contains headings for specific plants as well as many plant families and general plant terms such as PLANTS, MEDICINAL and PLANTS, TOXIC. Also several headings for plant components such as PLANT LEAVES and PLAINT ROOTS are included in this tree. Significant medical and historical plants are listed under their specific names (CINCHONA, DIGITALIS, EUCALYPTUS, etc.) Food plants are also in Category J2 - FOOD AND BEVERAGES. If the specific plant is available in MeSH, use it. Isolation of alpha-galactosidase from barley. BARLEY / * enzymol ALPHA-GALACTOSIDASE /* isol If the specific plant is not a MeSH heading, try to determine the family or group to which it belongs using information in the text or reference material. If that cannot be determined, index under PLANTS. Use the term PLANTS, EDIBLE and its indentions only for plants discussed as food. Superoxide dismutase activity in carnations. PLANTS / * enzymol SUPEROXIDE DISMUTASE metab Structural genes of petunias. *GENES, STRUCTURAL, PLANT SOLANACEAE / *genet Pesticide residues in fruits and vegetables. VEGETABLES / * chem FRUIT/ * chem PESTICIDE RESIDUES /* anal 22.31 Index SPORES, SPORES, BACTERIAL and SPORES, FUNGAL under the name of the organism (IM) and the SPORES term (NIM). If the point of the article is the spore, with the identity of the bacterium, fungus, or plant incidental, index the spore term (IM). In some cases, both the spore term and the organism can be IM. 22.32 MeSH provides the heading FUNGI and many specific fungi terms. In the absence of a specific genus, index a fungus under the next higher taxonomic group that is a MeSH term. If the author does not identify the group to which a particular fungus belongs, the indexer must consult Ainsworth and Bisby's Dictionary of the Fungi. The fungus to be indexed will almost always be identifiable here or by some clue in the text. Diseases caused by fungi are called MYCOSES and are listed in Category C1. 22.33 The check tag ANIMAL must be checked for any term used from Category B1 or B2. These are invertebrate and vertebrate animals and must be made available with the ANIMAL tag to allow the searcher to differentiate articles on them from articles on the HUMAN or on Categories B3 through B7 which receive no tags. Except for CHICK EMBRYO, the animal tags are mammals commonly used in experimental research. Any animal used in an experiment will be covered in indexing either by checking the tag or indexing the MeSH heading. In general, index the routine experimental animal as a check tag or as NIM without a subheading. If a routinely experimental animal is the point of the article and not experimental, index IM with an appropriate subheading. Index the non-routine animal - even in an experimental study - IM with a subheading. Amino acid metabolism in the liver. (Materials and Methods indicates the liver came from a cow) AMINO ACIDS / * metab LIVER / * metab CATTLE (check tag) ANIMAL (check tag) Platelet adhesiveness in different breeds of cattle. CATTLE / * blood *PLATELET ADHESIVENESS ANIMAL (check tag) COMPARATIVE STUDY (check tag) Amino acid metabolism in the liver of the lion. AMINO ACIDS /* metab LIONS / * metab LIVER / * metab ANIMAL (check tag) (The lion is not a typical experimental animal, so it is IM) 22.34 When indexing an organ from an invertebrate, index the specific animal (IM) and the organ (NIM). The structure of the mouth of the mosquito. MOSQUITOES / * anat MOUTH / anat ANIMAL (check tag) When indexing a physiological process in an invertebrate, index the specific animal (IM) and the process (NIM). Reproduction in snails. SNAILS / * physiol REPRODUCTION (NIM) ANIMAL (check tag) In cellular or ultrastructural studies using invertebrates, distinguish those studies in which the animal itself is being studied from those in which the animal is an experimental source of cellular or subcellular material. In the first case, the invertebrate would be IM and the cellular term would be IM or NIM. In the second case the invertebrate would be NIM and the cellular term would be IM. Glucose consumption in tick mitochondria. (Article is from a parasitology journal) GLUCOSE / * metab MITOCHONDRIA / * metab TICKS/ * metab / ultrastruct ANIMAL (check tag) Calcium metabolism in axons. (Materials and methods indicates the squid giant axon was used) CALCIUM / * metab AXONS / * metab SQUID ANIMAL (check tag) 22.35 When any animal is indexed IM, it will almost always have a subheading. Since so many subheadings are available to Category B terms, one usually applies. Anatomical or physiological studies on animals, especially in comparative anatomy and comparative physiology, are routinely IM with a subheading. In veterinary articles, index the normal veterinary animal IM with a subheading. In veterinary disease articles, index the animal with a subheading (IM) if one reasonably applies, otherwise index the animal IM with no subheading. Index any techniques used in these articles with the subheading /veterinary if it is permitted. See section 23.33. Differences in blood pressure between rabbits and squirrels. RABBITS / * physiol SQUIRRELS / * physiol *BLOOD PRESSURE SPECIES SPECIFICITY ANIMAL (check tag) COMPARATIVE STUDY (check tag) Histology of the swine liver. SWINE / * anat LIVER / * anat ANIMAL (check tag) Isolation of Trichinella from infected deer. TRICHINELLA / * isol DEER / * parasitol TRICHINOSIS / * vet / parasitol ANIMAL (check tag) Prevalence of hepatitis in parrots. HEPATITIS, ANIMAL / * epidemiol BIRD DISEASES / * epidemiol *PARROTS PREVALENCE ANIMAL (check tag) The economic importance of swine. *SWINE *ECONOMICS ANIMAL (check tag) Determination of antibodies to swine influenza virus in pigs by ELISA. SWINE / * immunol SWINE INFLUENZA VIRUS / * immunol ANTIBODIES, VIRAL / * blood ELISA / * vet ANIMAL (check tag) 22.36 Index inbred strains of rats or mice under RATS, INBRED STRAINS or MICE, INBRED STRAINS or one of the specifics treed under these terms. If a strain is a cross between two inbred strains index under both terms. If the strain is a cross between a strain for which there is no MeSH term and one for which there is a MeSH term, index under both the specific and MICE, INBRED STRAINS. (CBA x C57BL) mice MICE, INBRED CBA MICE, INBRED C57BL ANIMAL (check tag) (B10.A x A/wysn) mice MICE, INBRED A MICE, INBRED STRAINS ANIMAL (check tag)