BIOTECHNOLOGY

Affymetrix–GE Healthcare (formerly Molecular Dynamics)

Helping to Decode the Genome

A Patent Tree is a graphical display of knowledge dissemination from patented technological advances produced during an ATP-funded project. Some companies file for and are granted patents derived from their ATP project. Many of these patents are later referenced by other companies, thereby increasing the potential impact of the ATP project to propel the technology forward.


Patent trees for Status Report 94-05-0016 were generated during April 2007.

		Patent Trees Listed by:
	Patent		Patent Number	Company
·	“Denaturing separation matrix having hydroxyethyl cellulose for nucleic acid electrophoresis” (No. 5,534,123: filed July 10, 1995, granted July 19, 1996)		5,534,123	Molecular Dynamics
·	“Aminosilane/carbodiimide coupling of DNA to glass substrate“ (No. 5,760,130: filed May 13, 1997, granted June 2, 1998)		5,760,130	Molecular Dynamics
·	“Computer-aided probability base calling for arrays of nucleic acid probes on chips” (No. 5,733,729: filed September 14, 1995, granted March 31, 1998)		5,733,729	Affymetrix
·	“Integrated nucleic acid diagnostic device” (No 5,856,174: filed January 19, 1996, granted January 5, 1999)		5,856,174	Affymetrix
·	“Synthesis of oligonucleotide arrays using photocleavable protecting groups” (No. 6,022, 963: filed April 10, 1996, granted February 8, 2000)		6,022, 963	Affymetrix
·	“Integrated nucleic acid diagnostic device” (No. 5,922,591: filed June 27, 1996, granted July 13, 1999)		5,922,591	Affymetrix
·	“Photocleavable protecting groups and methods for their use” (No. 6,147,205: filed March 5, 1997, granted November 14, 2000)		6,147,205	Affymetrix
·	“Computer-aided techniques for analyzing biological sequences” (No. 6,600,996: filed March 28, 1997, granted July 29, 2003)		6,600,996	Affymetrix
·	“Computer-aided probability base calling for arrays of nucleic acid probes on chips” (No. 6,066,454: filed October 10, 1997, granted May 23, 2000)		6,066,454	Affymetrix
·	“Miniaturized genetic analysis systems and methods” (No. 6,168,948: filed January 12, 1998, granted January 2, 2001)		6,168,948	Affymetrix
·	“Process for microfabrication of an integrated PCR-CE device and products produced by the same” (No. 6,261,431: filed December 28, 1998, granted July 17, 2001)		6,261,431	Affymetrix
·	“Techniques for identifying confirming mapping and categorizing nucleic acids” (No. 7,099,777: filed January 11, 1999, granted August 29, 2006)		7,099,777	Affymetrix
·	“Integrated nucleic acid diagnostic device” (No. 6,197,595: filed April 19, 1999, granted March 6, 2001)		6,197,595	Affymetrix
·	“Systems and methods for high performance scanning” (No. 6,545,264: filed August 26, 1999, granted April 8, 2003)		6,545,264	Affymetrix
·	“Products and methods for analyzing nucleic acids including identification of substitutions, insertions and deletions” (No. 6,699,659; filed December 21, 1999, granted March 2, 2004)		6,699,659	Affymetrix
·	“System and method for self-calibrating measurement” (No. 6,612,737: filed December 29, 1999, granted September 2, 2003)		6,612,737	Affymetrix
·	“Computer-aided probability base calling for arrays of nucleic acid probes on chips” (No. 6,228,593: filed January 14, 2000, granted May 8, 2001)		6,228,593	Affymetrix
·	“Method of manipulating a gas bubble in a microfluidic device” (No. 6,326,211: filed March 10, 2000, granted December 4, 2001)		6,326,211	Affymetrix
·	“Photocleavable protecting groups and methods for their use” (No. 6,566,515: filed March 14, 2000, granted May 20, 2003)		6,566,515	Affymetrix
·	“Capillary array electrophoresis scanner” (No. 6,554,986: filed May 25, 2000, granted April 29, 2003)		6,554,986	Affymetrix
·	“Integrated nucleic acid diagnostic device” (No. 6,830,936: filed December 31, 2000, granted December 14, 2004)		6,830,936	Affymetrix
·	“Nucleic acid labeling compounds” (No. 6,596,856: filed February 9, 2001, granted July 22, 2003)		6,596,856	Affymetrix
·	“Computer-aided probability base calling for arrays of nucleic acid probes on chips” (No. 6,546,340: filed March 20, 2001, granted April 8, 2003)		6,546,340	Affymetrix
·	“Nucleic acid labeling compounds” (No. 6,965,020: filed September 11, 2001, granted November 15, 2005)		6,965,020	Affymetrix
·	“Capillary array electrophoresis scanner” (No. 7,090,758: filed October 31, 2002, granted August 15, 2006)		7,090,758	Affymetrix
·	“Biotin containing C-glycoside nucleic acid labeling compounds” (No. 6,864,059: filed December 5, 2002, granted March 8, 2005)		6,864,059	Affymetrix
·	“Photocleavable protecting groups and methods for their use” (No. 6,881,836: filed January 22, 2003, granted April 19, 2005)		6,881,836	Affymetrix
·	“Computer-aided probability base calling for arrays of nucleic acid probes on chips” (No. 6,957,149: filed April 1, 2003, granted October 18, 2005)		6,957,149	Affymetrix
·	“Nucleic acid labeling compounds” (No. 6,844,433: filed June 2, 2003, granted January 18, 2005)		6,844,433	Affymetrix