Lima MB, Pires ML, Silva MA, Ribero JE, Alessandro FA, Dimetz T, Povoa LC; International Conference on AIDS.

Int Conf AIDS. 1994 Aug 7-12; 10: 198 (abstract no. PB0807).

University of Rio de Janeiro, Brasil.

OBJECTIVE: Evaluate the thyroid function reserve in the bearers of HIV, in different stages of the infection. METHODS: 34 patients (pt), between 20-50 years old, without previous history of thyroid disease or use of drugs that could interfere in the thyroid function, were classified in 4 clinical groups (G): 8 pt with anti-HIV tests (-) (GI-control) and 26 pt with anti-HIV tests (+), among these pt 9 pt non symtomatics (GII), 9 pt with ARC(GIII) and 8 pt with AIDS (GIV). The evaluation was made by the seric hormonal dosages of TSH, T3, T4, free T3, free T4, in basal state and 30-60-120 minutes after intravenous injection of 200mcg of TRH(Thyrotropin Releasing Hormone). The used statistic methods were ANOVA and Newman-Kews. RESULTS: High levels of basal TSH were found in 2 pt from the GIII (22, 2%) and hyperresponse to TRH were observed 30 minutes after stimulation in 4 pt from the GIII (44.4%) and 2 pt from the GIV (25%). Seric measures of the T3, T4, free T3, free T4 in basal and after stimulation were in the hormonal range. CONCLUSIONS: There are difference statistically significative (p 0.005) among valves of TSH in 30 and 60 minutes after stimulation between the groups. Exagerated response of TSH to TRH in the groups III and IV may reflect subclinical hypothyroidim as a consequence of the subjacent infection by HIV in the thyroid.

Publication Types:

• Meeting Abstracts

Keywords:

• AIDS-Related Complex
• Acquired Immunodeficiency Syndrome
• HIV Infections
• HIV Seropositivity
• Humans
• Thyroid Diseases
• Thyroid Function Tests
• Thyroid Gland
• Thyrotropin-Releasing Hormone
• Thyroxine
• Thyroxine-Binding Proteins
• Triiodothyronine
• organization & administration

Other ID:

• 94371427

UI: 102210260

From Meeting Abstracts