| US 7,388,202 B2 | ||
| Method and apparatus for determining an analyte concentration in a sample having interferents | ||
| Bernhard B. Sterling, Danville, Calif. (US); W. Dale Hall, Oakland, Calif. (US); Kenneth G. Witte, San Jose, Calif. (US); Mark Wechsler, San Mateo, Calif. (US); Peng Zheng, Alameda, Calif. (US); and Richard Keenan, Livermore, Calif. (US) | ||
| Assigned to OptiScan Biomedical Corporation, Hayward, Calif. (US) | ||
| Filed on Oct. 21, 2005, as Appl. No. 11/256,656. | ||
| Claims priority of provisional application 60/724199, filed on Oct. 06, 2005. | ||
| Claims priority of provisional application 60/652660, filed on Feb. 14, 2005. | ||
| Claims priority of provisional application 60/621281, filed on Oct. 21, 2004. | ||
| Prior Publication US 2006/0197015 A1, Sep. 07, 2006 | ||
| Int. Cl. G01J 1/00 (2006.01); G01N 21/35 (2006.01) | ||
| U.S. Cl. 250—339.07 [250/339.08; 356/39; 356/300; 422/67] | 34 Claims |
| 1. A method for estimating the concentration of an analyte in a sample from a single measurement of the sample, said method
comprising:
providing a sample containing an analyte;
providing reference population data stored in computer memory, the reference population data derived from a source other than
the source of the sample;
providing a library of potential interferent data stored in computer memory;
measuring a spectrum of the sample and recording the measurement in computer memory;
using a computer processor to analyze the spectrum and identify in the sample, based on said measurement and said library
of potential interferent data, one or more possible interferents to a measurement of the analyte;
using the reference population data and the potential interferent data to calculate a calibration that is specific to the
measurement and reduces error attributable to said one or more possible interferents;
applying the calibration to the measurement of the sample; and
estimating, based on the calibrated measurement, the analyte concentration in the sample; and
recording the estimated analyte concentration in computer memory.
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