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UGID:1782750     UniGene Hs.567261     Homo sapiens (human)   MARK2 Order cDNA clone, Links
Protein-serine/threonine kinase gene (MARK2)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001115591.1 PREDICTED: MAP/microtubule affinity-regulating kinase 2 isoform 7 M. mulatta 100.0 787
NP_001034558.1 MAP/microtubule affinity-regulating kinase 2 isoform d H. sapiens 100.0 754
XP_001488382.2 PREDICTED: MAP/microtubule affinity-regulating kinase 2 E. caballus 99.6 787
NP_031954.2 MAP/microtubule affinity-regulating kinase 2 isoform 1 M. musculus 99.1 775
NP_001080425.1 MAP/microtubule affinity-regulating kinase 2 X. laevis 91.3 783
XP_686552.2 PREDICTED: wu:fc75f05 isoform 1 D. rerio 87.0 720
NP_995900.1 par-1 CG8201-PA, isoform A D. melanogaster 73.8 691
NP_001041145.1 abnormal embryonic PARtitioning of cytoplasm family member (par-1) C. elegans 64.1 1053
NP_974375.1 AKIN11 (ARABIDOPSIS SNF1 KINASE HOMOLOG 11); protein kinase A. thaliana 54.4 333
NP_010765.1 AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; Snf1p S. cerevisiae 50.7 473
XP_001698727.1 hypothetical protein CHLREDRAFT_106184 C. reinhardtii 50.7 304

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; epididymis; pharynx; uncharacterized tissue; placenta; mammary gland; intestine; larynx; lymph; embryonic tissue; uterus; ovary; pancreas; lung; mixed; prostate; pituitary gland; kidney; mouth; cervix; testis; heart; adrenal gland; liver; thyroid; blood; eye; skin; stomach; ascites; bone; muscle; vascular; salivary gland; bladder; connective tissue; nerve; thymus; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q12-q13
UniSTS entry: Chr 11 RH47044
UniSTS entry: Chr 11 (n/a)
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

BT007342.1 Homo sapiens MAP/microtubule affinity-regulating kinase 2 mRNA, complete cds P
NM_004954.3 Homo sapiens MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 2, mRNA PA
CR602633.1 full-length cDNA clone CS0DI010YC19 of Placenta Cot 25-normalized of Homo sapiens (human) P
AB188493.1 Homo sapiens Mark2 mRNA for serine/threonine kinase, complete cds, clone: TH033C09 P
BC084540.1 Homo sapiens MAP/microtubule affinity-regulating kinase 2, mRNA (cDNA clone MGC:99619 IMAGE:4591688), complete cds PA
NM_017490.2 Homo sapiens MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1, mRNA PA
AY562188.1 Homo sapiens ser/thr protein kinase Emk1/MARK2 isoform EMK1C mRNA, partial cds, alternatively spliced
AY562187.1 Homo sapiens ser/thr protein kinase Emk1/MARK2 isoform EMK1A mRNA, partial cds, alternatively spliced
NM_001039469.1 Homo sapiens MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 4, mRNA P
NM_001039468.1 Homo sapiens MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 3, mRNA PA
AK225766.1 Homo sapiens mRNA for Splice isoform 5 of Q7KZI7 variant, clone: FCC133G06 PA
BC008771.2 Homo sapiens MAP/microtubule affinity-regulating kinase 2, mRNA (cDNA clone IMAGE:3139103), partial cds PA
X97630.1 H.sapiens mRNA for serine/threonine protein kinase EMK P
AF387638.1 Homo sapiens Ser/Thr protein kinase PAR-1Balpha mRNA, complete cds P
AK290339.1 Homo sapiens cDNA FLJ76779 complete cds, highly similar to Homo sapiens MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1, mRNA P
AB271694.1 Homo sapiens Par1b mRNA for Ser/Thr protein kinase PAR-1Balpha splicing variant, complete cds P
AK307858.1 Homo sapiens cDNA, FLJ97806 P
Z25427.1 H.sapiens protein-serine/threonine kinase gene, complete CDS P

EST sequences (257)

BX112443.1 Clone IMAGp998P02137_;_IMAGE:25665 brain PA
AI248877.1 Clone IMAGE:1977720 brain 3' read
CB117860.1 Clone B1T694954-12-C04 brain 5' read
AI333598.1 Clone IMAGE:1931781 mixed 3' read P
R39857.1 Clone IMAGE:25665 brain 3' read
AI370467.1 Clone IMAGE:2046350 embryonic tissue 3' read
AI380486.1 Clone IMAGE:2106993 uncharacterized tissue 3' read
AI394102.1 Clone IMAGE:2109445 uncharacterized tissue 3' read
AI472858.1 Clone IMAGE:2147259 mixed 3' read
AI524222.1 Clone IMAGE:2117951 uncharacterized tissue 3' read
AI308067.1 Clone IMAGE:2055117 kidney 3' read
AI625067.1 Clone IMAGE:2231917 uterus 3' read
AI700064.1 Clone IMAGE:2242925 uncharacterized tissue 3' read
AI801226.1 Clone IMAGE:2185159 stomach 3' read
AI805264.1 Clone IMAGE:2073466 uncharacterized tissue 3' read
AI818608.1 Clone IMAGE:2421160 pancreas 3' read
AI832194.1 Clone IMAGE:2075597 intestine 3' read P
AI915252.1 Clone IMAGE:2268376 uterus 3' read
AI917172.1 Clone IMAGE:2237024 uncharacterized tissue 3' read
AI933326.1 Clone IMAGE:2466728 brain 3' read P
CB989872.1 Clone IMAGE:30341846 placenta 5' read
CB961570.1 Clone IMAGE:30337855 placenta 5' read
BX344699.2 Clone CS0DL006YA10 uncharacterized tissue 5' read P
BX363849.2 Clone CS0DL006YA10 uncharacterized tissue 5' read P
AI870094.1 Clone IMAGE:2437053 uterus 3' read
BX383835.2 Clone CS0DK001YH09 cervix 3' read P
BX383836.2 Clone CS0DK001YH09 cervix 5' read P
BX418485.2 Clone CS0DF005YN02 brain 5' read PA
AI971236.1 Clone IMAGE:2488855 prostate 3' read
CD512974.1 Clone IMAGE:30392875 pituitary gland 5' read
CD580511.2 Clone MPMGp800O07602 brain 5' read
BX390284.2 Clone CS0DI010YC19 placenta 5' read
AW135824.1 Clone IMAGE:2714429 mixed 3' read A
AW138519.1 Clone IMAGE:2713291 mixed 3' read A
AW150937.1 Clone IMAGE:2630223 uterus 3' read
AW170496.1 Clone IMAGE:2698312 cervix 3' read A
AW204622.1 Clone IMAGE:2719513 mixed 3' read A
AW207235.1 Clone IMAGE:2722143 mixed 3' read PA
AW263719.1 Clone IMAGE:2753784 lung 3' read
AW276603.1 Clone IMAGE:2760357 lung 3' read
AW368774.1 mouth
AW368797.1 mouth P
AW411326.1 Clone IMAGE:2964636 muscle 3' read A
R70970.1 Clone IMAGE:142637 placenta 5' read
AW674200.1 Clone IMAGE:2843167 cervix 3' read
CK819920.1 Clone IMAGE:5677453 pancreas 5' read
AW860437.1 intestine P
AW892631.1 brain P
AW896218.1 brain P
AW896297.1 brain
AW896724.1 brain P
CN263902.1 embryonic tissue 5' read A
AW955660.1 uncharacterized tissue P
CN289334.1 embryonic tissue 5' read
CN294691.1 embryonic tissue 5' read
AW959288.1 uncharacterized tissue P
CN428666.1 embryonic tissue 5' read P
CN428667.1 embryonic tissue 5' read P
CN428668.1 embryonic tissue 5' read P
CN428669.1 embryonic tissue 5' read P
CN428670.1 embryonic tissue 5' read
AW996866.1 mammary gland P
BE090027.1 mammary gland
BE090074.1 mammary gland P
H19443.1 Clone IMAGE:51515 brain 5' read P
BE263670.1 Clone IMAGE:3536064 lung 5' read
BE268634.1 Clone IMAGE:3345436 lymph 5' read PM
BE268688.1 Clone IMAGE:3345437 lymph 5' read PM
BE272588.1 Clone IMAGE:3347650 kidney 5' read P
BE278938.1 Clone IMAGE:3139550 placenta 5' read P
BE280645.1 Clone IMAGE:3139103 placenta 5' read PM
BE281234.1 Clone IMAGE:3138845 placenta 5' read PM
H25205.1 Clone IMAGE:52310 brain 5' read P
H25218.1 Clone IMAGE:52524 brain 5' read P
CV337476.1 epididymis P
CV349107.1 larynx
CV358997.1 intestine P
CV361130.1 larynx P
CV361131.1 larynx P
BE397682.1 Clone IMAGE:3620437 lymph 5' read PM
BE467171.1 Clone IMAGE:3212571 lung 3' read
BE513752.1 Clone IMAGE:3634045 lymph 5' read
BE546985.1 Clone IMAGE:3457935 cervix 5' read P
BE718515.1 pharynx P
BE718568.1 pharynx P
BE718578.1 pharynx P
BE718584.1 pharynx
BE718591.1 pharynx P
BE718595.1 pharynx P
BE718601.1 pharynx P
BE718623.1 pharynx P
BE718632.1 pharynx P
BE718642.1 pharynx P
BE718669.1 pharynx P
BE718671.1 pharynx P
BE795309.1 Clone IMAGE:3940970 lung 5' read P
BE798169.1 Clone IMAGE:3937130 lung 5' read P
BE872187.1 Clone IMAGE:3850417 intestine 5' read PM
DN997339.1 Clone TC117049 mammary gland 5' read P
DN998185.1 Clone TC114124 mammary gland 5' read P
DN999964.1 Clone TC104486 vascular 5' read P
BE889867.1 Clone IMAGE:3913348 uterus 5' read P
BE901257.1 Clone IMAGE:3958725 placenta 5' read P
BF002715.1 Clone IMAGE:3310834 prostate 3' read
BF095318.1 uterus P
CR977450.1 Clone RZPDp9017H031 uncharacterized tissue 5' read P
CR998003.1 Clone RZPDp9017C0924 uncharacterized tissue 5' read P
BF132552.1 Clone IMAGE:3930554 salivary gland 5' read
AU133733.1 Clone OVARC1000550 ovary 5' read P
BF223900.1 Clone IMAGE:3700185 uncharacterized tissue 3' read
BF305215.1 Clone IMAGE:4138408 muscle 5' read
BF310039.1 Clone IMAGE:4138040 muscle 5' read
AA837805.1 Clone IMAGE:1410706 prostate
DA039570.1 Clone BLADE2000506 bladder 5' read P
DA133501.1 Clone BRALZ2005794 brain 5' read P
DA620224.1 Clone JCMLC2001607 uncharacterized tissue 5' read P
BF854303.1 lung
DA426977.1 Clone COLON2002324 intestine 5' read P
DA388836.1 Clone BRTHA2025204 brain 5' read P
DA452296.1 Clone CTONG2024927 mouth 5' read P
DA374997.1 Clone BRTHA2006132 brain 5' read P
BF057129.1 Clone IMAGE:3444411 uncharacterized tissue 3' read
BF064170.1 Clone IMAGE:3323689 intestine 3' read
DA453306.1 Clone CTONG2026187 mouth 5' read P
DB042310.1 Clone TESTI2029632 testis 5' read P
DA917542.1 Clone SMINT2002232 intestine 5' read
BF434069.1 Clone IMAGE:3644213 ovary 3' read P
DA999129.1 Clone TBAES2000471 mammary gland 5' read P
DA999670.1 Clone TBAES2001157 mammary gland 5' read
DA855402.1 Clone PLACE7006121 placenta 5' read
DA753944.1 Clone NT2RP7020264 testis 5' read P
BF477766.1 Clone IMAGE:3676691 prostate 3' read
DA826864.1 Clone PERIC2008333 heart 5' read P
DA716054.1 Clone NT2RI2023496 5' read P
BF590710.1 Clone IMAGE:3318373 intestine 3' read
BF793893.1 Clone IMAGE:4347334 adrenal gland 5' read
BF796693.1 Clone IMAGE:4341555 lymph 5' read P
DB273542.1 Clone UTERU2036210 uterus 5' read P
BF748175.1 mammary gland P
DB172949.1 Clone TKIDN2008320 kidney 5' read P
DB246533.1 Clone TUTER2002834 uterus 5' read P
BF755756.1 intestine P
DB371310.1 Clone OVARC1000550 ovary 3' read
DW421079.1 liver
BF829171.1 thyroid P
BG036548.1 Clone IMAGE:4427836 prostate 5' read P
BG005113.1 placenta
BG009485.1 placenta P
BF992934.1 placenta P
BF953367.1 brain P
BF899776.1 blood P
BF908721.1 uterus P
BF915328.1 uterus
BF879910.1 lung
BG178446.1 Clone IMAGE:4431370 prostate 5' read A
DB532131.1 Clone H023016M14 brain 3' read
DB534688.1 Clone H023029D06 brain 3' read
BG248986.1 Clone IMAGE:4470250 kidney 5' read A
DB471827.1 Clone H023053E02 brain 5' read
DB540575.1 Clone H023053E02 brain 3' read
AL547060.3 Clone CS0DI010YC19 placenta 5' read P
AL572263.3 Clone CS0DI010YC19 placenta 3' read
BG419875.1 Clone IMAGE:4591688 kidney 5' read P
BG421251.1 Clone IMAGE:4589914 kidney 5' read P
BG386422.1 Clone IMAGE:4584059 intestine 5' read P
BG751648.1 Clone IMAGE:4874295 eye 5' read P
BG822223.1 Clone IMAGE:4865588 intestine 5' read P
BG825423.1 Clone IMAGE:4899824 muscle 5' read P
BI084508.1 Clone IMAGE:5013783 salivary gland 3' read
BI046915.1 prostate P
BG987798.1 larynx P
BG994839.1 larynx P
BG956269.1 intestine P
BG957538.1 intestine P
BG978142.1 intestine P
BI194858.1 Clone IMAGE:5091963 brain 5' read P
BI254921.1 Clone IMAGE:5114786 cervix 5' read
BI261575.1 Clone IMAGE:5087872 lymph 5' read
DC303895.1 Clone BRACE2020552 brain 5' read P
DC329271.1 Clone BRCOC2014714 brain 5' read P
BI521469.1 Clone IMAGE:5220523 mixed 5' read P
BI522272.1 Clone IMAGE:5220523 mixed 3' read P
BI712851.1 Clone IMAGE:5085582 pancreas 5' read P
BI754464.1 Clone IMAGE:5193310 brain 5' read
BI764231.1 Clone IMAGE:5186330 mixed 5' read P
BI836292.1 Clone IMAGE:5223400 mixed 5' read
BI791440.1 Clone IMAGE:5085582 pancreas 3' read
BI914353.1 Clone IMAGE:5246314 brain 5' read
BI911013.1 Clone IMAGE:5217728 blood 5' read P
BM091088.1 pancreas 5' read P
BM091391.1 pancreas 3' read P
BM142145.1 Clone IMAGE:5677453 pancreas 5' read
BM263187.1 Clone IMAGE:5678304 pancreas 5' read
BM550195.1 Clone IMAGE:5443403 brain 5' read P
BM554541.1 Clone IMAGE:5469491 skin 5' read P
BM562341.1 Clone IMAGE:5480896 skin 5' read P
BM664867.1 Clone UI-E-CQ1-aey-i-14-0-UI brain 3' read A
BM669839.1 Clone UI-E-DX1-agx-c-04-0-UI eye 3' read A
BM699176.1 Clone UI-E-DX1-agx-c-04-0-UI eye 5' read P
BM700779.1 Clone UI-E-CL1-aej-c-08-0-UI eye 5' read
BM702173.1 Clone UI-E-CQ1-aey-i-14-0-UI brain 5' read A
BM724555.1 Clone UI-E-EO1-aiz-d-22-0-UI eye 5' read P
BM728424.1 Clone UI-E-EJ0-aiu-g-21-0-UI eye 5' read
BM744045.1 Clone S1SNU5s1-4-E01 ascites 5' read
BM762212.1 Clone S13KMS5-10-G09 stomach 5' read
BM773084.1 Clone S3SNU16s1-13-E10 ascites 5' read P
BM800604.1 Clone IMAGE:5535131 uterus 5' read
BM809029.1 Clone IMAGE:5734481 brain 5' read
BM912060.1 Clone IMAGE:5473546 skin 5' read P
BM912801.1 Clone IMAGE:5474769 skin 5' read P
BM914849.1 Clone IMAGE:5480565 skin 5' read P
BM968066.1 Clone UI-CF-DU1-aaq-f-10-0-UI lung 3' read PA
BM974073.1 Clone UI-CF-EC1-abz-d-23-0-UI lung 3' read A
BM978379.1 Clone UI-CF-EC1-aeb-p-20-0-UI lung 3' read A
BQ066750.1 Clone IMAGE:5931421 lymph 5' read
BQ069131.1 Clone IMAGE:5803418 brain 5' read P
BQ081899.1 Clone S1SNU5s1-5-E01 ascites 5' read
BQ300544.1 bladder P
BQ307765.1 mammary gland P
BQ347973.1 mouth P
BQ368548.1 placenta P
BQ379699.1 uterus P
BF920198.1 brain P
BG115773.1 Clone IMAGE:4417222 intestine 5' read
BI919160.1 Clone IMAGE:5242855 brain 5' read P
BQ918813.1 Clone IMAGE:6378046 brain 5' read P
BQ955537.1 Clone IMAGE:6200081 nerve 5' read
BU153870.1 Clone IMAGE:6093048 pancreas 5' read
BU196137.1 Clone IMAGE:6093493 pancreas 5' read P
BU160588.1 Clone IMAGE:6147390 skin 5' read
BU509067.1 Clone IMAGE:6503611 uterus 5' read
BU168880.1 Clone IMAGE:6086169 pancreas 5' read P
AA159979.1 Clone IMAGE:592748 pancreas 5' read
AA159980.1 Clone IMAGE:592748 pancreas 3' read
BU608410.1 Clone UI-CF-FN0-aeo-f-13-0-UI lung 3' read PA
BU626211.1 Clone UI-H-FG1-bgq-h-17-0-UI bone 3' read PA
BU617710.1 Clone UI-H-DF0-beq-p-04-0-UI bone 3' read A
BU849317.1 Clone IMAGE:6597714 mixed 5' read P
T75020.1 Clone HCoE28 intestine 5' read P
CA425198.1 Clone UI-H-DF0-bel-k-23-0-UI bone 3' read A
CA427749.1 Clone UI-H-DF0-bes-c-02-0-UI bone 3' read A
CA433996.1 Clone UI-H-DF0-arq-j-17-0-UI bone 3' read A
CA434080.1 Clone UI-H-DF0-arq-j-17-0-UI bone 3' read A
CA444563.1 Clone UI-H-DT1-awl-g-14-0-UI connective tissue 3' read PA
CA444975.1 Clone UI-H-DT1-awm-f-23-0-UI connective tissue 3' read A
AA324104.1 brain 5' read
T78364.1 Clone IMAGE:24155 brain 5' read P
AA329979.1 embryonic tissue 5' read
AA369656.1 placenta 5' read
AA383948.1 thymus 5' read P
AA531246.1 Clone IMAGE:985800 prostate 3' read
AA568276.1 Clone IMAGE:1057603 intestine 3' read
AA613444.1 Clone IMAGE:1145533 intestine 3' read
AA617763.1 Clone IMAGE:1130206 mammary gland 3' read
AA813690.1 Clone 1376248 testis 3' read A
AA827742.1 Clone IMAGE:1335672 lymph node 3' read
R12018.1 Clone IMAGE:25665 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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