Paterson DL, Allworth AM, Kemp RJ; Australasian Society for HIV Medicine. Conference.
Annu Conf Australas Soc HIV Med. 1995 Nov 16-19; 7: 96 (abstract no. 121).
Department of Infectious Diseases, Royal Brisbane Hospital.
Salmonella infection is a common occurrence in patients with AIDS - an indication of the need for intact cell-mediated immunity to control this organism. While diarrhoea is the usual presenting symptom, we have noted several unusual extraintestinal manifestations of this infection. In the last three years, we have isolated Salmonella species from 7 patients with AIDS - 2 from faeces only, 2 from faeces and blood, and three from other sites (bone in 2 and testis in 1). Both of our patients with salmonella osteomyelitis had CD4 counts of less than 0.05 x 10(9)/l. One presented with acute onset of leg pain and fever - Salmonella enteritidis was isolated from blood cultures and bone scan showed features of osetoemyelitis in the tibia. Three months later he developed pain in his shoulder - biopsy of the humerus grew Salmonella enteritidis. He had no further recurrences with long-term ciprofloxacin. The second patient had acute onset of rib pain - blood cultures grew Salmonella and bone scan was consistent with osteomyelitis. Urogenital infections with Salmonella are uncommon. A 47 year old man under our care with CD4 count of 0.04 x 10(9)/L developed rigors and a swollen, painful left testis. A diagnosis of epididymo-orchitis was made. Blood cultures were sterile. He was initially treated with amoxycillin and gentamicin with initial prompt defeverescence. Three weeks later his symptoms worsened however, prompting orchidectomy. Salmonella typhimurium was grown from the resected testis. Salmonellosis is common in patients with AIDS and extraintestinal manifestations need to be considered in the differential diagnosis of unexplained fever, bone pain or orchitis.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- CD4 Lymphocyte Count
- Diagnosis, Differential
- Epididymitis
- Fever
- Humans
- Male
- Orchiectomy
- Orchitis
- Osteomyelitis
- Salmonella
- Salmonella Food Poisoning
- Salmonella Infections
- Salmonella enteritidis
- Salmonella typhimurium
- surgery
Other ID:
UI: 102215370
From Meeting Abstracts