Gala C, Ducati A, Donati R, Vianello L, Mansi M, Martini S; International Conference on AIDS.
Int Conf AIDS. 1989 Jun 4-9; 5: 465 (abstract no. Th.B.P.297).
Institute of Psychiatry, University of Milan, Italy
OBJECTIVE: Evaluation of cortical function impairment in the early course of HIV infection, by means of multimodality evoked potentials (MEPs). METHODS: 20 HIV infected subjects were studied (16 homosexual males, 2 heterosexual males, two heterosexual females). They were seropositive for at least 6 months before entering the protocol. All subjects underwent a session of MEP recording that included brainstem acoustic evoked potentials (BAEPs), somatosensory evoked potentials (SEPs), pattern reversal visual evoked potentials (PR-VEPs). The same session was repeated between 6 and 8 months after the first one, in the same subjects. RESULTS: Electrophysiological data referring to the first session demonstrated a significant change of cortical responses in more than 50% of subjects. The data of the second recording did not show an increase of the percentage of abnormal results in the same group of subjects, but in 3 patients, whose response were already pathological, a definite worsening was observed. CONCLUSION: Our results suggest that the involvement of the cerebral cortex takes place early in the course of the HIV infection.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Brain Stem
- Cerebral Cortex
- Evoked Potentials
- Evoked Potentials, Somatosensory
- Evoked Potentials, Visual
- Female
- HIV Infections
- HIV Seropositivity
- Humans
- Longitudinal Studies
- Male
- Monitoring, Physiologic
Other ID:
UI: 102178307
From Meeting Abstracts