Chouaid C, Cadranel J, Winter C, Mehoyas MC; International Conference on AIDS.
Int Conf AIDS. 1991 Jun 16-21; 7: 223 (abstract no. M.B.2165).
St Antoine Hospital, Paris, FRANCE
In HIV-infected patients (pts) with pleural effusion (P.E), the usual diagnostic problem is to distinguish between the two main causes which are infection and Kaposi's sarcoma (K.S). The objective of this retrospective study is to determine the contribution of clinical and radiological examination and analysis of pleural fluid (P.F) in the diagnosis of pleural effusion due to K.S (K.S-P.E) as opposed to infectious causes. METHODS: Between 1988 and 1990, 58 HIV-infected pts were admitted to the East Paris Hospitals because of P.E due to either K.S on macroscopical and pathological diagnostic criteria, (Group I, n=32) or to an infectious cause on microbiological criteria, (Group II, n=26). In both groups, clinical, radiological and biological data were analyzed particularly: 1) risk factors for HIV infection; 2) presence and progression of an associated cutaneous K.S; 3) acute or progressive onset of P.E; 4) degree of resultant fever; 5) volume and bilaterality of P.E; 6) presence and bilaterality of associated pulmonary infiltrates and 7) macroscopic nature and biological data of P.F. RESULTS: clinical features of K.S-P.E compared with infectious P.E were: 1) associated cutaneous K.S (G I 31/32 vs G II 6/26; p less than 0,001) with an evolutive pattern (G I 29/31 vs G II 0/6; p less than 0,001); 2) progressive onset greater than 10 days (G I 28/32 vs G II 8/26; p less than 0,001); 3) temperature less than 38 degrees c (G I 28/32 vs G II 6/26; p less than 0,001); 4) bilateral P.E (G I 29/32 vs G II 2/26; p less than 0,001); 5) bilateral associated pulmonary infiltrates (G I 28/32 vs G II 3/26; p less than 0,001) and 6) sero-haemorrhagic P.F (G I 28/32 vs G II 7/26; p less than 0,001). CONCLUSION: in an HIV-infected pt with P.E, clinical and radiological data are highly suggestive of K.S as the cause and so highly contributive to the following diagnostic and therapeutic approach.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Disease Progression
- HIV Infections
- HIV Seropositivity
- Humans
- Paris
- Pleural Effusion
- Retrospective Studies
- Sarcoma, Kaposi
- diagnosis
- etiology
Other ID:
UI: 102183088
From Meeting Abstracts