Mora CA, Altieri R, Davaro M, Miglioranza C, Laurido M, Ezcurra C, Stecher D, Lasala MB; International Conference on AIDS.
Int Conf AIDS. 1996 Jul 7-12; 11: 296 (abstract no. Th.B.4264).
Division of Infectious Disease, J. M. San Martin Hospital, School of Medicine, Buenos Aires, Argentina.
Objective: The aim of the present study was to determine the epidemilogic, clinical and laboratory characteristics and the outcome of the intestinal parasitosis in a cohort of HIV patients(P). Method: Clinical records were retrospectively analyzed. The rate of positive stool samples (PS) and the incidence of each parasitic infestation were determined. The risk behaviors (RB) for HIV were related to the PS. Diarrhea(D), fever, abdominal pain(AP), eosinophilia(E), anemia(A), increased alkaline phosphatase(IaP) were all correlated with the incidence of PS and with the parasites detected. Statistical methods:Relative risk(RR). x2, Yates corrected and Fisher exact test. Results: Study period: 1/1/1987-12/31/1995. Follow-up: mean 26.8 months. Stool specimens(s) 376. P 218. .PS: 200 (53.2%). RB: homosexuality and bisexuality 169(84,5%) p is less than .0001/RR 1,74. CI 95%:1,29-2.35; IVDA 27 (13.5%); others:16 (8%). Parasite/specimen ratio: 1.84. Parasites detected: B. hominis: 97s, E. nana (En): 56s; E. hystolitica (Eh): 48s; E. coli: 46s; G. lamblia (Gl): 39s; I. butschilli: 27s; D. fragilis: 23s; Cryptosporidium(C): lls; I. belli (I); 4s; S. estercoralis (Ss): 3s; uncinaria (U): 1s., others:13s. No correlation was found between clinical symptoms or laboratory data, including CD4 count, and PS. A significant correlation was found between: C and D(p is less than .001/RR2.09 CI95%2.95-5.67); C and AP (p is less than .001/RR9.95 CI95%3.85-23.68); C and A (RR 3.82, CI95% 2.01-7.20); C and IaP (RR 3.97, CI95% 1.32-11.89); C and CD4 less than 200/mm3 (RR9.87, CI95% 2.68- 36.34). G1. and D (p is less than .002, RR2.19, CI95% 1.39- 3.43). E and En (RR 2.57, CI95% 0.94-7), U (RR15.31, CI95% 9.05-25.89) and Ss (RR10.94, CI95% 4.15- 28.97). A and Ib (RR3. 16, CI95% 1.138.87). Pathologic parasites other than C and Ib persisted after treatment in 20,3% and C and Ib in 54,5%. (p is less than .02/RR2.62, CI95%: 1.30 - 5.29) and was not related with CD4 count. (p is less than 0.1/RR2,14. CI 95%: 0.87-5.28.) Conclusions: Asymptomatic parasitic intestinal infestation is frequent in HIV patients. The presence of D, AP, increased PA and CD4 count less than 200/mm3 preclude the C stool detection. The identification of some parasites is related to the CD4 count but the success of treatment dependes on the parasite.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Bisexuality
- CD4 Lymphocyte Count
- Diarrhea
- Feces
- HIV Infections
- HIV Seropositivity
- Humans
- Incidence
- Intestines
- Parasitic Diseases
- Substance Abuse, Intravenous
Other ID:
UI: 102220554
From Meeting Abstracts