Elghouzzi MH, Ferrer-le-Coeur F, Courouce AM, Jullien AM, Rannou C, Beige D; International Conference on AIDS.
Int Conf AIDS. 1992 Jul 19-24; 8: 163 (abstract no. PuC 8065).
Fondation Nationale de Transfusion Sanguine, Les Ulis, France.
OBJECTIVES: To determine the difference of HTLV-I transmission determinants between 3 ethnic groups of antibodies HTLV I/II positive blood donors living in Paris area. METHODS: The blood donations were screened by Elisa Organon Teknika. When Elisa was repeatedly positive, Western-Blot was used to confirm HTLV-I infection. Risk factors of seropositive donors and their family were determined during medical consultation. RESULTS: 39 blood donors were found antibodies HTLV-I (Ab HTLV I/II) positive (1989-1991). 29 were born in French West Indies (FWI), 3 in Western Africa and 7 in France (7 women). 31/39 blood donors, 11 partners and 25 children were examined, interviewed and tested. Among partners native of FWI and tested : 1/7 Male(M) and 1/1 Female(F) were Ab HTLV-I positive. None of the 2 African F partners of one donor, and none of the 2 French M partners of 2 F donors from home France was Ab HTLV positive. Among 25 children, 22 were born of 8 mothers with Ab HTLV-I positive and breast-fed (greater than 5 months), none were Ab HTLV-I positive. TABULAR DATA, SEE ABSTRACT VOLUME. CONCLUSION: Birth in endemic areas associated with sexual transmission is the main risk factor. Sexual and post-transfusion transmissions are evident risk factors for women born in Continental France. In this study conducted in non endemic area, the breast-feeding transmission seems to be reduced because of the absence of cofactors.
Publication Types:
Keywords:
- Africa, Western
- Antibodies
- Antibodies, Viral
- Blood Donors
- Blotting, Western
- Child
- Deltaretrovirus Antibodies
- Enzyme-Linked Immunosorbent Assay
- Ethnic Groups
- Family
- Female
- France
- HTLV-I Antibodies
- HTLV-I Infections
- HTLV-II Antibodies
- Human T-lymphotropic virus 1
- Humans
- Male
- Paris
- Risk Factors
- West Indies
- transmission
Other ID:
UI: 102201456
From Meeting Abstracts