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Chair's Introduction (Marwald). The morphology of the cardiac condunction system (Anderson and Ho). Development of the cardiac conduction system: a matter of chamber development (Moorman and Crhistoffels). Mouse models for cardiac conduction system development (Wessels et al). Developmental transitions in cardiac conduction (Watanabe et al). Gap junctional connexins in developing mouse cardiac conduction system (Miquerol et al). His-Purkinje lineages and development (Gourdie et al). The role of neural crest and epicardium-derived cells in conduction system formation (Gittenberger-de Groot et al). Induction and patterning of the Purkinje fibre network (Mikawa et al). The oldest, toughest cells in the heart (Thompson et al). Transcriptional regulation in the mouse atrioventricular conduction system (Edwards et al). Pattterning of the mouse conduction system (Rentschler et al). Clinical pathology of the cardiac conduction system (Ho). Cardiac conduction and arrhythmia: insights from Nkx2:5 mutations in mouse and humans (Jay et al). The genetic origin of atrioventricular conduction disturbance in humans (Benson). Defects in cardiac conduction system lineages and malignant arrhythmias: developmental pathways and disease (St. Armand et al). Final general discussion. Index of contributors. Subject index.