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Monday,
October 1 |
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8:00 –
8:10 a.m. |
Welcome and Opening Remarks
Manfred Boehm, M.D., Cardiology Branch, Division of Intramural Research, NHLBI |
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8:10 – 8:30 a.m. |
The NHLBI Investment in Stem Cell Research
Elizabeth G. Nabel, M.D., Director, NHLBI
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8:30 – 10:05 a.m. |
Session I: Lessons From Hematopoiesis
Chairs:
David T. Scadden, M.D., Harvard Medical School and Massachusetts General Hospital
Cynthia Dunbar, M.D., Hematology Branch, Division of Intramural Research, NHLBI |
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8:30 – 8:35 a.m. |
Introduction to topic and speakers – session chairs |
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8:35 – 9:00 a.m. |
Got Niche?
David T. Scadden, M.D., Harvard Medical School and Massachusetts General Hospital
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9:00 – 9:25 a.m. |
Contributions of the Blood System to Lineage Programming and Reprogramming
Stuart H. Orkin, M.D., Harvard Medical School
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9:25 – 9:50 a.m. |
Possible Mechanisms Underlying the Greater Potency of Adult Stem Cells?
Catherine Verfaillie, M.D., Katholieke Universiteit Leuven
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9:50 – 10:05 a.m. |
Roundtable discussion |
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10:05 – 10:20 a.m. |
Break |
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10:20 a.m. – 12:20 p.m. |
Session II: Fate and Specification in Embryonic Stem Cells
Chairs:
Kenneth R. Chien, M.D., Ph.D., Harvard Medical School
Natalie DeWitt, Ph.D., Nature |
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10:20 – 10:25 a.m. |
Introduction to topic and speakers – session chairs |
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10:25 – 10:50 a.m. |
Derivation of Hematopoietic Cells From Human Embryonic Stem Cells
Mickie Bhatia, Ph.D., McMaster University
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10:50 – 11:15 a.m. |
Generation of Germline-Competent Induced Pluripotent Cells
Shinya Yamanaka, M.D., Ph.D., Kyoto University and University of California, San Francisco |
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11:15 a.m. – 11:40 p.m. |
Multipotent isl1+ Cardiovascular Progenitors
Kenneth R. Chien, M.D., Ph.D., Harvard Medical School
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11:40 – 12:05 p.m. |
Dissecting Self-Renewal in Stem Cells With RNA Interference
Natalia B. Ivanova, Ph.D., Princeton University |
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12:05 – 12:20 p.m. |
Roundtable discussion |
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12:20
– 1:15 p.m. |
Lunch (on your own) |
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1:15 – 3:15 p.m. |
Session III: Vascular Regeneration – Where Vasculogenesis and Angiogenesis Collide
Chairs:
Stefanie Dimmeler, Ph.D., University of Frankfurt
Manfred Boehm, M.D., Cardiology Branch, Division of Intramural Research, NHLBI
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1:15 – 1:20 p.m. |
Introduction to topic and speakers – session chairs |
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1:20 – 1:45 p.m. |
VEGFs for More Vessels and Muscle
Kari Alitalo, M.D., Ph.D., University of Helsinki
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1:45 – 2:10 p.m. |
Thymosin b4 Promotes Neovascularisation via Adult Epicardium: Translating Its Potential as a Novel Angiogenic Therapy
Paul R. Riley, Ph.D., Institute of Child Health |
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2:10 – 2:35 p.m. |
Endothelial Progenitor Cells for Vascular Medicine
Takayuki Asahara, M.D., Ph.D., RIKEN Center for Developmental Biology/IBRI, Tokai University
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2:35 – 3:00 p.m. |
Circulating Progenitor Cells: Characterisation and Mechanisms of Action
Stefanie Dimmeler, Ph.D., University of Frankfurt
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3:00 – 3:15 p.m. |
Roundtable discussion |
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3:15 – 3:30 p.m. |
Break |
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3:30 – 5:30 p.m. |
Session IV: Cardiac Regeneration I – Heart Development and Cardiac Regeneration
Chairs:
Jonathan A. Epstein, M.D., University of Pennsylvania School of Medicine
Cecilia Lo, Ph.D., Laboratory of Developmental Biology, Division of Intramural Research, NHLBI
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3:30 – 3:35 p.m. |
Introduction to topic and speakers – session chairs |
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3:35 – 4:00 p.m. |
microRNA Regulation of Cell Lineages in Mouse and Human Embryonic Stem Cells
Deepak Srivastava, M.D., University of California, San Francisco |
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4:00 – 4:25 p.m. |
Multipotent Progenitor Cells in the Developing and Adult Murine Heart
Richard Harvey, Ph.D., Victor Chang Cardiac Research Institute, University of New South Wales |
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4:25 – 4:50 p.m. |
Maintaining the Undifferentiated State
Jonathan A. Epstein, M.D., University of Pennsylvania School of Medicine |
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4:50 – 5:15 p.m. |
Cardiac Myogenesis in Embryonic Stem Cells
Michael D. Schneider, M.D., Imperial College London
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5:15 – 5:30 p.m. |
Roundtable discussion |
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5:30 p.m. |
Adjournment |
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5:45 – 6:45 p.m. |
Poster Session and Networking Hour |
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Tuesday, October 2, 2007 |
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8:00 – 10:25 a.m. |
Session V: Toward Progenitor and Stem Cell-based Therapy – Lessons Learned from Large Animal Models and Clinical Trials
Chairs:
Joshua M. Hare, M.D., Miller School of Medicine–University of Miami
Philippe Menasché , M.D., Ph.D., Hôpital Européen Georges
Pompidou
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8:00 – 8:05 a.m. |
Introduction to topic and speakers – session chairs |
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8:05 – 8:30 a.m. |
Mechanisms of Action and Clinical Utility of Mesenchymal Stem Cells in Cardiac Repair
Joshua M. Hare, M.D., Miller School of Medicine–University of Miami
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8:30 – 8:55 a.m. |
Autologous CD34 Cell Therapy for Ischemic Tissue Repair
Douglas W. Losordo, M.D., Northwestern University
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8:55 – 9:20 a.m. |
Lessons Learned From Large Animal Models and Clinical Trials
Philippe Menasché , M.D., Ph.D., Hôpital Européen Georges
Pompidou |
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9:20 – 9:45 a.m. |
Clinical Benefit of Progenitor Cell Therapy in Acute Myocardial Infarction: Mechanisms and Future Directions
Andreas M. Zeiher, M.D., University of Frankfurt
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9:45 – 10:10 a.m. |
Defining Human Endothelial Progenitor Cells
Mervin C. Yoder, Jr., M.D., Indiana University School of Medicine
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10:10 – 10:25 a.m. |
Roundtable discussion |
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10:25 – 10:40 a.m. |
Break |
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10:40 a.m. – 1:05 p.m. |
Session VI: Cardiac Regeneration II – Adult Cardiac Muscle Progenitors
Chairs:
Catherine Verfaillie, M.D., Katholieke Universiteit Leuven
Michael D. Schneider, M.D., Imperial College London
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10:40 – 10:45 a.m. |
Introduction to topic and speakers – session chairs |
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10:45 – 11:10 a.m. |
Human Cardiac Stem Cells
Piero Anversa, M.D., New York Medical College |
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11:10 – 11:35 a.m. |
Cardiac Stem Cells From Human Endomyocardial Biopsies
Eduardo Marbán, M.D., Ph.D., Johns Hopkins University School of Medicine
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11:35 – 12:00 p.m. |
Cardiac Side Population Cells: Role of BCRP1
Ronglih Liao, Ph.D., Brigham and Women's Hospital
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12:00 – 12:25 p.m. |
Repairing the Infarcted Heart: Roles for Endogenous and Exogenous Stem Cells
Charles E. Murry, M.D., Ph.D., University of Washington Medical Center |
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12:25 – 12:50 p.m. |
Periostin Induces Proliferation
of Differentiated Cardiomyocytes
and Promotes Cardiac Repair
Bernhard Kuhn, M.D., Children's Hospital, Boston
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12:50 – 1:05 p.m. |
Roundtable discussion |
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1:05 – 2:00 p.m. |
Lunch (on your own) |
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2:00 – 2:40 p.m. |
Session VII: Selected Talks |
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2:00 – 2:05 p.m. |
Introduction to session |
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2:05 – 2:15 p.m. |
Fate Mapping of Neointima Formation in a Murine Vein-Arterial Graft Model
Jason Mellad, Cardiology Branch, Division of Intramural Research, NHLBI
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2:15 – 2:25 p.m. |
Transplanted Human Embryonic Stem Cell-derived Cardiomyocytes Form Grafts in Nude Rat Hearts Exposed to Ischemia/Reperfusion
Wangde Dai, M.D., The Heart Institute, Good Samaritan Hospital, University of Southern California
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2:25 – 2:40 p.m. |
NHLBI Cardiovascular Cell-Based Network
Sonia I. Skarlatos, Ph.D., FAHA, Division of Cardiovascular Diseases, Division of Extramural Research, NHLBI |
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2:40 – 4:40 p.m. |
Session VIII: Regenerative Medicine Technologies
Chairs:
Loren J. Field, Ph.D., Indiana University
Robert Balaban, Ph.D., Laboratory of Cardiac Energetics, Division of Intramural Research, NHLBI
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2:40 – 2:45 p.m. |
Introduction to topic and speakers – session chairs |
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2:45 – 3:10 p.m. |
Developmental Reprogramming After Chromosome Transfer Into Mitotic Mouse Zygotes
Dieter Egli , Ph.D., Harvard Medical School
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3:10 – 3 :35 p.m. |
A New Approach for Tracking Cell Fate in Animals – and Potentially Humans
Richard T. Lee, M.D., Brigham and Women's Hospital |
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3:35 – 4:00 p.m. |
Monitoring Myogenic Donor Cells: The Good, the Bad and the Ugly
Loren J. Field, Ph.D., Indiana University School of Medicine
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4:00 – 4:25 p.m. |
Multimodality Imaging for the Assessment of Myocardial Cell Therapy
Albert C. Lardo, Ph.D., Johns Hopkins University School of Medicine |
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4:25 – 4:40 p.m. |
Roundtable discussion |
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4:40 – 5:00 p.m. |
Concluding Remarks and Adjournment
Manfred Boehm, M.D., Cardiology Branch, Division of Intramural Research, NHLBI |
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Last modified:September 26, 2007 |
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