UNTIL THE TWENTIETH CENTURY, smoking cigarettes and pipes was one of the only ways of introducing medications directly into an asthma patient's bronchial tubes and lungs. Patients smoked several different medicinal substances to treat their asthma, including nitrate powders, tobacco, cubeb, and plant-derived stramonium. By the late 1800s, experimenters were working on other methods to deliver medications into the lungs using air or steam instead of smoke.

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