Poster Sessions

Epi-15

Porcia Bradford

P. Bradford, S. Devesa, J. Toro

Cutaneous Lymphoma Incidence Patterns in the United States: A Population-based study of 4,064 cases

Background: Cutaneous lymphomas (CL) are a heterogenous group of neoplasms. There have been no prior large population-based studies specific to CL in the USA. Methods: Using the Surveillance, Epidemiology and End Results (SEER) program, we analyzed incidence (IR) and relative survival rates of CL according to race, gender, and histologic type. Results: 4,064 CL were diagnosed in the 16 SEER registries during 2001-2005. T-cell lymphomas (CTCL) accounted for 72% of CL cases, while B cell lymphomas (CBCL) accounted for 28%. The overall age-adjusted CL IR was 11.7/1,000,000 person-years, with Non-Hispanic Whites having the highest IR (12.2) and Asian/Pacific Islanders having the lowest (7.2). CTCL IR were highest among Blacks, whereas CBCL IR were highest and almost exclusive to Non-Hispanic whites. Males had higher IR for both cell types of CL and their histologic subtypes. The 5-year relative survival rates for CTCL and CBCL were 86% and 88%, respectively. During 1973-2005, the IR for CTCL increased from 2.5/ 1,000,000 to 9.4/1,000,000 person-years. However, rates stabilized from 1995 to 2005. Rates of CBCL from 1992 to 2005 have remained relatively stable. Conclusion: CL rates vary markedly by race, gender, and histological type, supporting that the histologic variants of CL are etiologically distinct.