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HFE Entrez Gene digest
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GeneRIFs
Hemochromatosis
Entrez Gene GeneRIFs are recent publications from the PubMed® catalog that contain relevant information about HFE.
Adams LA, Angulo P, Abraham SC, Torgerson H, Brandhagen D. The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis. Liver Int. 2006 Apr;26(3):298-304.
PubMed citation
Adams PC, Reboussin DM, Barton JC, Acton RT, Speechley M, Leiendecker-Foster C, Meenan R, Passmore L, McLaren CE, McLaren GD, Gordeuk V, Dawkins F, Eckfeldt JH. Serial serum ferritin measurements in untreated HFE C282Y homozygotes in the Hemochromatosis and Iron Overload Screening Study. Int J Lab Hematol. 2008 Aug;30(4):300-5.
PubMed citation
Adams PC, Reboussin DM, Barton JC, McLaren CE, Eckfeldt JH, McLaren GD, Dawkins FW, Acton RT, Harris EL, Gordeuk VR, Leiendecker-Foster C, Speechley M, Snively BM, Holup JL, Thomson E, Sholinsky P; Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators. Hemochromatosis and iron-overload screening in a racially diverse population. N Engl J Med. 2005 Apr 28;352(17):1769-78.
PubMed citation
Adams PC, Reboussin DM, Press RD, Barton JC, Acton RT, Moses GC, Leiendecker-Foster C, McLaren GD, Dawkins FW, Gordeuk VR, Lovato L, Eckfeldt JH. Biological variability of transferrin saturation and unsaturated iron-binding capacity. Am J Med. 2007 Nov;120(11):999.e1-7.
PubMed citation
Agarwal S, Tewari D, Arya V, Moorchung N, Tripathi R, Chaudhuri G, Pradhan M. Status of HFE mutation in thalassemia syndromes in north India. Ann Hematol. 2007 Jul;86(7):483-5. Epub 2007 Mar 31.
PubMed citation
Akbas N, Hochstrasser H, Deplazes J, Tomiuk J, Bauer P, Walter U, Behnke S, Riess O, Berg D. Screening for mutations of the HFE gene in Parkinson's disease patients with hyperechogenicity of the substantia nigra. Neurosci Lett. 2006 Oct 16;407(1):16-9. Epub 2006 Aug 28.
PubMed citation
Alizadeh BZ, Njajou OT, Hazes JM, Hofman A, Slagboom PE, Pols HA, van Duijn CM. The H63D variant in the HFE gene predisposes to arthralgia, chondrocalcinosis and osteoarthritis. Ann Rheum Dis. 2007 Nov;66(11):1436-42. Epub 2007 Feb 6.
PubMed citation
Allen KJ, Gurrin LC, Constantine CC, Osborne NJ, Delatycki MB, Nicoll AJ, McLaren CE, Bahlo M, Nisselle AE, Vulpe CD, Anderson GJ, Southey MC, Giles GG, English DR, Hopper JL, Olynyk JK, Powell LW, Gertig DM. Iron-overload-related disease in HFE hereditary hemochromatosis. N Engl J Med. 2008 Jan 17;358(3):221-30.
PubMed citation
Anderson GJ, Ramm GA, Subramaniam VN, Powell LW. HFE gene and hemochromatosis. J Gastroenterol Hepatol. 2004 Jun;19(6):712. No abstract available.
PubMed citation
Aranda N, Viteri FE, Fernández-Ballart J, Murphy M, Arija V. Frequency of the hemochromatosis gene (HFE) 282C-->Y, 63H-->D, and 65S-->C mutations in a general Mediterranean population from Tarragona, Spain. Ann Hematol. 2007 Jan;86(1):17-21. Epub 2006 Sep 30.
PubMed citation
Arnold J, Sangwaiya A, Bhatkal B, Arnold A. Defective release of Hepcidin not defective synthesis is the primary pathogenic mechanism in HFE-Haemochromatosis. Med Hypotheses. 2008;70(6):1197-200. Epub 2007 Dec 3.
PubMed citation
Arredondo M, Tapia V, Rojas A, Aguirre P, Reyes F, Marzolo MP, Núñez MT. Apical distribution of HFE-beta2-microglobulin is associated with inhibition of apical iron uptake in intestinal epithelia cells. Biometals. 2006 Aug;19(4):379-88.
PubMed citation
Asberg A, Hveem K, Kannelønning K, Irgens WØ. Penetrance of the C28Y/C282Y genotype of the HFE gene. Scand J Gastroenterol. 2007 Sep;42(9):1073-7.
PubMed citation
Asberg A, Thorstensen K, Hveem K, Bjerve KS. Hereditary hemochromatosis: the clinical significance of the S65C mutation. Genet Test. 2002 Spring;6(1):59-62.
PubMed citation
Avila-Gomez IC, Aristizabal-Bernal B, Jimenez-Del-Rio M, Velez-Pardo C. Prevalence of H63D, S65C and C282Y mutations of the HFE gene in 1120 voluntary blood donors from Antioquia region of northwest Colombia. Blood Cells Mol Dis. 2008 May-Jun;40(3):449-51. Epub 2008 Mar 4. No abstract available.
PubMed citation
Avila-Gomez IC, Jiménez-Del-Rio M, Lopera-Restrepo F, Velez-Pardo C. Association between HFE 187 C>G (H63D) mutation and early-onset familial Alzheimer's disease PSEN-1 839A>C (E280A) mutation. Ann Hematol. 2008 Aug;87(8):671-3. Epub 2008 Mar 8. No abstract available.
PubMed citation
Avila-Gomez IC, Latorre-Sierra G, Restrepo-Gutierrez JC, Correa-Arango G, Jimenez-Del-Rio M, Velez-Pardo C. Analysis of the HFE gene (H63D and C282Y) mutations in patients with iron overload, family members and controls from Antioquia, Northwest Colombia. Clin Genet. 2008 Jan;73(1):92-3. Epub 2007 Nov 13. No abstract available.
PubMed citation
Bacon BR, Powell LW, Adams PC, Kresina TF, Hoofnagle JH. Molecular medicine and hemochromatosis: at the crossroads. Gastroenterology. 1999 Jan;116(1):193-207. No abstract available.
PubMed citation
Baptista-González HA, Rosenfeld-Mann F, Trueba-Gómez R, Bermejo-Martínez L, Méndez-Sánchez N. Association of HFE mutations (C282Y and H63D) with iron overload in blood donors from Mexico City. Ann Hepatol. 2007 Jan-Mar;6(1):55-60.
PubMed citation
Barry E, Derhammer T, Elsea SH. Prevalence of three hereditary hemochromatosis mutant alleles in the Michigan Caucasian population. Community Genet. 2005;8(3):173-9.
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Barton JC, Lee PL, West C, Bottomley SS. Iron overload and prolonged ingestion of iron supplements: clinical features and mutation analysis of hemochromatosis-associated genes in four cases. Am J Hematol. 2006 Oct;81(10):760-7.
PubMed citation
Barton JC, Wiener HW, Acton RT, Go RC. HLA haplotype A*03-B*07 in hemochromatosis probands with HFE C282Y homozygosity: frequency disparity in men and women and lack of association with severity of iron overload. Blood Cells Mol Dis. 2005 Jan-Feb;34(1):38-47.
PubMed citation
Bennett MJ, Lebrón JA, Bjorkman PJ. Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor. Nature. 2000 Jan 6;403(6765):46-53.
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Bennett MJ, Lebrón JA, Bjorkman PJ. Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor. Nature. 2000 Jan 6;403(6765):46-53.
PubMed citation
Benyamin B, McRae AF, Zhu G, Gordon S, Henders AK, Palotie A, Peltonen L, Martin NG, Montgomery GW, Whitfield JB, Visscher PM. Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. Am J Hum Genet. 2009 Jan;84(1):60-5. Epub 2008 Dec 11.
PubMed citation
Berlin D, Chong G, Chertkow H, Bergman H, Phillips NA, Schipper HM. Evaluation of HFE (hemochromatosis) mutations as genetic modifiers in sporadic AD and MCI. Neurobiol Aging. 2004 Apr;25(4):465-74.
PubMed citation
Beutler E, Griffin MJ, Gelbart T, West C. A previously undescribed nonsense mutation of the HFE gene. Clin Genet. 2002 Jan;61(1):40-2.
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Beutler E, West C. Polymorphisms in the 5' flanking region of the HFE gene: linkage disequilibrium and relationship to iron homeostasis. Blood Cells Mol Dis. 2002 Mar-Apr;28(2):191-5.
PubMed citation
Bhatt L, Horgan CP, McCaffrey MW. Knockdown of beta2-microglobulin perturbs the subcellular distribution of HFE and hepcidin. Biochem Biophys Res Commun. 2009 Jan 23;378(4):727-31. Epub 2008 Dec 4.
PubMed citation
Bhatt L, Horgan CP, Walsh M, McCaffrey MW. The hereditary hemochromatosis protein HFE and its chaperone beta2-microglobulin localise predominantly to the endosomal-recycling compartment. Biochem Biophys Res Commun. 2007 Jul 27;359(2):277-84. Epub 2007 May 24.
PubMed citation
Biasiotto G, Goldwurm S, Finazzi D, Tunesi S, Zecchinelli A, Sironi F, Pezzoli G, Arosio P. HFE gene mutations in a population of Italian Parkinson's disease patients. Parkinsonism Relat Disord. 2008;14(5):426-30. Epub 2008 Mar 5.
PubMed citation
Bittencourt PL, Palácios SA, Couto CA, Cançado EL, Carrilho FJ, Laudanna AA, Kalil J, Gayotto LC, Goldberg AC. Analysis of HLA-A antigens and C282Y and H63D mutations of the HFE gene in Brazilian patients with hemochromatosis. Braz J Med Biol Res. 2002 Mar;35(3):329-35.
PubMed citation
Bonkovsky HL, Naishadham D, Lambrecht RW, Chung RT, Hoefs JC, Nash SR, Rogers TE, Banner BF, Sterling RK, Donovan JA, Fontana RJ, Di Bisceglie AM, Ghany MG, Morishima C; HALT-C Trial Group. Roles of iron and HFE mutations on severity and response to therapy during retreatment of advanced chronic hepatitis C. Gastroenterology. 2006 Nov;131(5):1440-51. Epub 2006 Aug 18.
PubMed citation
Bonkovsky HL, Troy N, McNeal K, Banner BF, Sharma A, Obando J, Mehta S, Koff RS, Liu Q, Hsieh CC. Iron and HFE or TfR1 mutations as comorbid factors for development and progression of chronic hepatitis C. J Hepatol. 2002 Dec;37(6):848-54.
PubMed citation
Botella-Carretero JI, Luque-Ramírez M, Alvarez-Blasco F, San Millán JL, Escobar-Morreale HF. Mutations in the hereditary hemochromatosis gene are not associated with the increased body iron stores observed in overweight and obese women with polycystic ovary syndrome. Diabetes Care. 2006 Nov;29(11):2556. No abstract available.
PubMed citation
Buchanan DD, Silburn PA, Chalk JB, Le Couteur DG, Mellick GD. The Cys282Tyr polymorphism in the HFE gene in Australian Parkinson's disease patients. Neurosci Lett. 2002 Jul 19;327(2):91-4.
PubMed citation
Candore G, Balistreri CR, Lio D, Mantovani V, Colonna-Romano G, Chiappelli M, Tampieri C, Licastro F, Branzi A, Averna M, Caruso M, Hoffmann E, Caruso C. Association between HFE mutations and acute myocardial infarction: a study in patients from Northern and Southern Italy. Blood Cells Mol Dis. 2003 Jul-Aug;31(1):57-62.
PubMed citation
Candore G, Licastro F, Chiappelli M, Franceschi C, Lio D, Rita Balistreri C, Piazza G, Colonna-Romano G, Grimaldi LM, Caruso C. Association between the HFE mutations and unsuccessful ageing: a study in Alzheimer's disease patients from Northern Italy. Mech Ageing Dev. 2003 Apr;124(4):525-8.
PubMed citation
Carru C, Pes GM, Deiana L, Baggio G, Franceschi C, Lio D, Balistreri CR, Candore G, Colonna-Romano G, Caruso C. Association between the HFE mutations and longevity: a study in Sardinian population. Mech Ageing Dev. 2003 Apr;124(4):529-32.
PubMed citation
Cauza E, Hanusch-Enserer U, Bischof M, Spak M, Kostner K, Tammaa A, Dunky A, Ferenci P. Increased C282Y heterozygosity in gestational diabetes. Fetal Diagn Ther. 2005 Sep-Oct;20(5):349-54.
PubMed citation
Chambers V, Sutherland L, Palmer K, Dalton A, Rigby AS, Sokol R, Pollitt R, Tanner S, Gleeson D. Haemochromatosis-associated HFE genotypes in English blood donors: age-related frequency and biochemical expression. J Hepatol. 2003 Dec;39(6):925-31.
PubMed citation
Chen J, Chloupková M, Gao J, Chapman-Arvedson TL, Enns CA. HFE modulates transferrin receptor 2 levels in hepatoma cells via interactions that differ from transferrin receptor 1-HFE interactions. J Biol Chem. 2007 Dec 21;282(51):36862-70. Epub 2007 Oct 23.
PubMed citation
Chitturi S, Weltman M, Farrell GC, McDonald D, Kench J, Liddle C, Samarasinghe D, Lin R, Abeygunasekera S, George J. HFE mutations, hepatic iron, and fibrosis: ethnic-specific association of NASH with C282Y but not with fibrotic severity. Hepatology. 2002 Jul;36(1):142-9. Erratum in: Hepatology 2002 Nov;36(5):1307.
PubMed citation
Costarelli S, Torti C, Gatta LB, Tinelli C, Lapadula G, Quiros-Roldan E, Izzo I, Castelnuovo F, Biasiotto G, Arosio P, Carosi G. No evidence of relation between peripheral neuropathy and presence of hemochromatosis gene mutations in HIV-1-positive patients. J Acquir Immune Defic Syndr. 2007 Oct 1;46(2):255-6. No abstract available.
PubMed citation
Cronin S, Blauw HM, Veldink JH, van Es MA, Ophoff RA, Bradley DG, van den Berg LH, Hardiman O. Analysis of genome-wide copy number variation in Irish and Dutch ALS populations. Hum Mol Genet. 2008 Nov 1;17(21):3392-8. Epub 2008 Aug 7.
PubMed citation
Cruz E, Porto G, Morais S, Campos M, de Sousa M. HFE mutations in the pathobiology of hemophilic arthropathy. Blood. 2005 Apr 15;105(8):3381-2. No abstract available.
PubMed citation
Cukjati M, Vaupotic T, Rupreht R, Curin-Serbec V. Prevalence of H63D, S65C and C282Y hereditary hemochromatosis gene mutations in Slovenian population by an improved high-throughput genotyping assay. BMC Med Genet. 2007 Nov 23;8:69.
PubMed citation
Cukjati M, Vaupotic T, Rupreht R, Curin-Serbec V. Prevalence of H63D, S65C and C282Y hereditary hemochromatosis gene mutations in Slovenian population by an improved high-throughput genotyping assay. BMC Med Genet. 2007 Nov 23;8:69.
PubMed citation
Curcio M, Fornaciari S, Mariotti ML, Chelazzi S, Scatena F, Presciuttini S. Haplotype analysis of the H63D, IVS2+4t/c, and C282Y polymorphisms of the HFE gene reveals rare events of intragenic recombination. Eur J Haematol. 2008 Apr;80(4):341-5. Epub 2007 Dec 21.
PubMed citation
Davies PS, Enns CA. Expression of the hereditary hemochromatosis protein HFE increases ferritin levels by inhibiting iron export in HT29 cells. J Biol Chem. 2004 Jun 11;279(24):25085-92. Epub 2004 Mar 25.
PubMed citation
Davies PS, Zhang AS, Anderson EL, Roy CN, Lampson MA, McGraw TE, Enns CA. Evidence for the interaction of the hereditary haemochromatosis protein, HFE, with the transferrin receptor in endocytic compartments. Biochem J. 2003 Jul 1;373(Pt 1):145-53.
PubMed citation
Davis TM, Beilby J, Davis WA, Olynyk JK, Jeffrey GP, Rossi E, Boyder C, Bruce DG. Prevalence, characteristics, and prognostic significance of HFE gene mutations in type 2 diabetes: the Fremantle Diabetes Study. Diabetes Care. 2008 Sep;31(9):1795-801. Epub 2008 Jun 19.
PubMed citation
de Almeida SF, Carvalho IF, Cardoso CS, Cordeiro JV, Azevedo JE, Neefjes J, de Sousa M. HFE cross-talks with the MHC class I antigen presentation pathway. Blood. 2005 Aug 1;106(3):971-7. Epub 2005 Apr 19.
PubMed citation
de Almeida SF, Picarote G, Fleming JV, Carmo-Fonseca M, Azevedo JE, de Sousa M. Chemical chaperones reduce endoplasmic reticulum stress and prevent mutant HFE aggregate formation. J Biol Chem. 2007 Sep 21;282(38):27905-12. Epub 2007 Jul 11.
PubMed citation
de Geus HR, Dees A. Sporadic porphyria cutanea tarda due to haemochromatosis. Neth J Med. 2006 Sep;64(8):307-9.
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Devaney J, Maher M, Smith T, Houghton JA, Glennon M. HFE alleles in an Irish cystic fibrosis population. Genet Test. 2003 Summer;7(2):155-8.
PubMed citation
Dhillon BK, Das R, Garewal G, Chawla Y, Dhiman RK, Das A, Duseja A, Chandak GR. Frequency of primary iron overload and HFE gene mutations (C282Y, H63D and S65C) in chronic liver disease patients in north India. World J Gastroenterol. 2007 Jun 7;13(21):2956-9.
PubMed citation
Dijck-Brouwer DA, Hepkema BG, van der Dijs FP, Steward HN, de Windt-Hol JM, Muskiet FA. Curaçao patients with coronary artery disease have a higher prevalence of the HFE C282Y mutation. West Indian Med J. 2004 Jun;53(3):143-6.
PubMed citation
Distante S. Genetic predisposition to iron overload: prevalence and phenotypic expression of hemochromatosis-associated HFE-C282Y gene mutation. Scand J Clin Lab Invest. 2006;66(2):83-100. Review. No abstract available.
PubMed citation
Dorak MT, Burnett AK, Worwood M. Hemochromatosis gene in leukemia and lymphoma. Leuk Lymphoma. 2002 Mar;43(3):467-77. Review.
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Dorak MT, Burnett AK, Worwood M. HFE gene mutations in susceptibility to childhood leukemia: HuGE review. Genet Med. 2005 Mar;7(3):159-68. Review.
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Drakesmith H, Chen N, Ledermann H, Screaton G, Townsend A, Xu XN. HIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasis. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11017-22. Epub 2005 Jul 25.
PubMed citation
Drakesmith H, Chen N, Ledermann H, Screaton G, Townsend A, Xu XN. HIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasis. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11017-22. Epub 2005 Jul 25.
PubMed citation
Drakesmith H, Chen N, Ledermann H, Screaton G, Townsend A, Xu XN. HIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasis. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11017-22. Epub 2005 Jul 25.
PubMed citation
Drakesmith H, Sweetland E, Schimanski L, Edwards J, Cowley D, Ashraf M, Bastin J, Townsend AR. The hemochromatosis protein HFE inhibits iron export from macrophages. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15602-7. Epub 2002 Nov 12.
PubMed citation
Duseja A, Das R, Nanda M, Das A, Garewal G, Chawla Y. Nonalcoholic steatohepatitis in Asian Indians is neither associated with iron overload nor with HFE gene mutations. World J Gastroenterol. 2005 Jan 21;11(3):393-5.
PubMed citation
Ekblom K, Hultdin J, Stegmayr B, Johansson I, Van Guelpen B, Hallmans G, Weinehall L, Johansson L, Wiklund PG, Marklund SL. Iron stores and HFE genotypes are not related to increased risk of ischemic stroke. A prospective nested case-referent study. Cerebrovasc Dis. 2007;24(5):405-11. Epub 2007 Sep 18.
PubMed citation
Ellervik C, Birgens H, Tybjaerg-Hansen A, Nordestgaard BG. Hemochromatosis genotypes and risk of 31 disease endpoints: meta-analyses including 66,000 cases and 226,000 controls. Hepatology. 2007 Oct;46(4):1071-80.
PubMed citation
Equitani F, Fernandez-Real JM, Menichella G, Koch M, Calvani M, Nobili V, Mingrone G, Manco M. Bloodletting ameliorates insulin sensitivity and secretion in parallel to reducing liver iron in carriers of HFE gene mutations. Diabetes Care. 2008 Jan;31(1):3-8. Epub 2007 Oct 24.
PubMed citation
Erhardt A, Maschner-Olberg A, Mellenthin C, Kappert G, Adams O, Donner A, Willers R, Niederau C, Häussinger D. HFE mutations and chronic hepatitis C: H63D and C282Y heterozygosity are independent risk factors for liver fibrosis and cirrhosis. J Hepatol. 2003 Mar;38(3):335-42.
PubMed citation
Erhardt A, Mellenthin C, Perings C, Hennersdorf M, Reinecke P, Strauer BE, Häussinger D. HFE mutations in idiopathic dilated cardiomyopathy. Med Klin (Munich). 2006 Mar 22;101 Suppl 1:135-8.
PubMed citation
Ezzikouri S, El Feydi AE, El Kihal L, Afifi R, Benazzouz M, Hassar M, Chafik A, Pineau P, Benjelloun S. Prevalence of common HFE and SERPINA1 mutations in patients with hepatocellular carcinoma in a Moroccan population. Arch Med Res. 2008 Feb;39(2):236-41.
PubMed citation
Feder JN, Penny DM, Irrinki A, Lee VK, Lebrón JA, Watson N, Tsuchihashi Z, Sigal E, Bjorkman PJ, Schatzman RC. The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding. Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1472-7.
PubMed citation
Feeney GP, Carter K, Masters GS, Jackson HA, Cavil I, Worwood M. Changes in erythropoiesis in hereditary hemochromatosis are not mediated by HFE expression in nucleated red cells. Haematologica. 2005 Feb;90(2):180-7.
PubMed citation
Fracanzani AL, Fargion S, Stazi MA, Valenti L, Amoroso P, Cariani E, Sangiovanni A, Tommasini M, Rossini A, Bertelli C, Fatta E, Patriarca V, Brescianini S, Stroffolini T. Association between heterozygosity for HFE gene mutations and hepatitis viruses in hepatocellular carcinoma. Blood Cells Mol Dis. 2005 Jul-Aug;35(1):27-32.
PubMed citation
Frank A, Seitz HK, Bartsch H, Frank N, Nair J. Immunohistochemical detection of 1,N6-ethenodeoxyadenosine in nuclei of human liver affected by diseases predisposing to hepato-carcinogenesis. Carcinogenesis. 2004 Jun;25(6):1027-31. Epub 2004 Jan 23.
PubMed citation
Frank J, Poblete-Gutiérrez P, Weiskirchen R, Gressner O, Merk HF, Lammert F. Hemochromatosis gene sequence deviations in German patients with porphyria cutanea tarda. Physiol Res. 2006;55 Suppl 2:S75-83.
PubMed citation
Gao J, Zhao N, Knutson MD, Enns CA. The hereditary hemochromatosis protein, HFE, inhibits iron uptake via down-regulation of Zip14 in HepG2 cells. J Biol Chem. 2008 Aug 1;283(31):21462-8. Epub 2008 Jun 4.
PubMed citation
Garewal G, Das R, Ahluwalia J, Marwaha RK. Prevalence of the H63D mutation of the HFE in north India: its presence does not cause iron overload in beta thalassemia trait. Eur J Haematol. 2005 Apr;74(4):333-6.
PubMed citation
Gehrke SG, Herrmann T, Kulaksiz H, Merle U, Bents K, Kaiser I, Riedel HD, Stremmel W. Iron stores modulate hepatic hepcidin expression by an HFE-independent pathway. Digestion. 2005;72(1):25-32. Epub 2005 Aug 10.
PubMed citation
Geier A, Reugels M, Weiskirchen R, Wasmuth HE, Dietrich CG, Siewert E, Gartung C, Lorenzen J, Bosserhoff AK, Brügmann M, Gressner AM, Matern S, Lammert F. Common heterozygous hemochromatosis gene mutations are risk factors for inflammation and fibrosis in chronic hepatitis C. Liver Int. 2004 Aug;24(4):285-94.
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Giannetti AM, Björkman PJ. HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface. J Biol Chem. 2004 Jun 11;279(24):25866-75. Epub 2004 Mar 31.
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Girouard J, Giguère Y, Delage R, Rousseau F. Prevalence of HFE gene C282Y and H63D mutations in a French-Canadian population of neonates and in referred patients. Hum Mol Genet. 2002 Jan 15;11(2):185-9.
PubMed citation
Gleeson D, Evans S, Bradley M, Jones J, Peck RJ, Dube A, Rigby E, Dalton A. HFE genotypes in decompensated alcoholic liver disease: phenotypic expression and comparison with heavy drinking and with normal controls. Am J Gastroenterol. 2006 Feb;101(2):304-10.
PubMed citation
Gonzalez-Hevilla M, de Salamanca RE, Morales P, Martínez-Laso J, Fontanellas A, Castro MJ, Rojo R, Moscoso J, Zamora J, Serrano-Vela JI, Arnaiz-Villena A. Human leukocyte antigen haplotypes and HFE mutations in Spanish hereditary hemochromatosis and sporadic porphyria cutanea tarda. J Gastroenterol Hepatol. 2005 Mar;20(3):456-62.
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Goodall EF, Greenway MJ, van Marion I, Carroll CB, Hardiman O, Morrison KE. Association of the H63D polymorphism in the hemochromatosis gene with sporadic ALS. Neurology. 2005 Sep 27;65(6):934-7.
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Gordeuk VR, Reboussin DM, McLaren CE, Barton JC, Acton RT, McLaren GD, Harris EL, Reiss JA, Adams PC, Speechley M, Phatak PD, Sholinsky P, Eckfeldt JH, Chen WP, Passmore L, Dawkins FW. Serum ferritin concentrations and body iron stores in a multicenter, multiethnic primary-care population. Am J Hematol. 2008 Aug;83(8):618-26.
PubMed citation
Goswami T, Andrews NC. Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing. J Biol Chem. 2006 Sep 29;281(39):28494-8. Epub 2006 Aug 7.
PubMed citation
Gruper Y, Bar J, Bacharach E, Ehrlich R. Transferrin receptor co-localizes and interacts with the hemochromatosis factor (HFE) and the divalent metal transporter-1 (DMT1) in trophoblast cells. J Cell Physiol. 2005 Sep;204(3):901-12.
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Guix P, Picornell A, Parera M, Galmes A, Obrador A, Ramon MM, Castro JA. Distribution of HFE C282Y and H63D mutations in the Balearic Islands (NE Spain). Clin Genet. 2002 Jan;61(1):43-8.
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Gunel-Ozcan A, Alyilmaz-Bekmez S, Guler EN, Guc D. HFE H63D mutation frequency shows an increase in Turkish women with breast cancer. BMC Cancer. 2006 Feb 19;6:37.
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Halling J, Petersen MS, Grandjean P, Weihe P, Brosen K. Genetic predisposition to Parkinson's disease: CYP2D6 and HFE in the Faroe Islands. Pharmacogenet Genomics. 2008 Mar;18(3):209-12.
PubMed citation
Halsall DJ, McFarlane I, Luan J, Cox TM, Wareham NJ. Typical type 2 diabetes mellitus and HFE gene mutations: a population-based case - control study. Hum Mol Genet. 2003 Jun 15;12(12):1361-5.
PubMed citation
Hannuksela J, Parkkila S, Waheed A, Britton RS, Fleming RE, Bacon BR, Sly WS. Human platelets express hemochromatosis protein (HFE) and transferrin receptor 2. Eur J Haematol. 2003 Apr;70(4):201-6.
PubMed citation
Hanson EH, Imperatore G, Burke W. HFE gene and hereditary hemochromatosis: a HuGE review. Human Genome Epidemiology. Am J Epidemiol. 2001 Aug 1;154(3):193-206. Review.
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Hellerbrand C, Pöppl A, Hartmann A, Schölmerich J, Lock G. HFE C282Y heterozygosity in hepatocellular carcinoma: evidence for an increased prevalence. Clin Gastroenterol Hepatol. 2003 Jul;1(4):279-84.
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Hicken BL, Calhoun DC, Tucker DC. Genetic testing for hemochromatosis: attitudes and acceptability among young and older adults. Genet Test. 2003 Fall;7(3):235-9.
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Hopkins MR, Ettinger AS, Hernández-Avila M, Schwartz J, Téllez-Rojo MM, Lamadrid-Figueroa H, Bellinger D, Hu H, Wright RO. Variants in iron metabolism genes predict higher blood lead levels in young children. Environ Health Perspect. 2008 Sep;116(9):1261-6.
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Hoppe C, Watson RM, Long CM, Lorey F, Robles L, Klitz W, Styles L, Vichinsky E. Prevalence of HFE mutations in California newborns. Pediatr Hematol Oncol. 2006 Sep;23(6):507-16.
PubMed citation
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Published: February 6, 2009