Backgrounder Harvard University-U.S. Department of Agriculture BSE Study The United States Department of Agriculture (USDA) is responsible for protecting both human and animal health and for ensuring the safety and security of our food supply. The Department's efforts have been effective in keeping bovine spongiform encephalopathy (BSE), a fatal neurodegenerative disease of cattle, out of the United States. BSE was first diagnosed in 1986 in the United Kingdom. It has since affected approximately 170,000 cattle in the U.K. and other European countries. Recent scientific studies suggest that BSE may be linked through consumption of BSE-infected tissues to new variant Creutzfeldt-Jakob disease, a fatal neurodegenerative disease in humans. USDA has taken aggressive measures to prevent the entry of BSE into the U.S. These measures include banning cattle and cattle products from countries where BSE has been reported or where adequate surveillance programs are not in place; monitoring and testing for BSE in U.S. cattle; and educating producers and the public about the disease. USDA has entered into a cooperative agreement with Harvard University's School of Public Health to begin an analysis and evaluation of the Department's current measures to prevent BSE. Harvard University researchers will review existing science on the disease in order to:  characterize the hazards of BSE and other transmissible spongiform encephalopathy agents to human and animal health  assess potential pathways that BSE could enter the U.S.  evaluate existing USDA regulations and policies  identify any additional preventive measures that could be taken While this study is being conducted, USDA will continue to aggressively test and monitor for BSE and will institute any preventive regulatory measures that are necessary. # April 24, 1998