X26C Publications

X26-C PRT for Protein Crystallography
CSHL, SUNYSB, GRA, BNL Bio

X26C
Results

	2006
		H.M. Berman, A.A. Napoli 5'-D(GPCPAPGPAPCPGPTPCPTPGPC)-3' Methionine Repressor binding site To be Published Medline Abstract; PDB file 2B1D
		M.C. Bewley, V. Graziano, J.S. Jiang E. Matz, F.W. Studier, A.P. Pegg, C.S. Coleman, J.M. Flanagan Structures of wild-type and mutant human spermidine/spermine N(1)-acetyltransferase, a potential therapeutic drug target. Proc.Natl.Acad.Sci. USA (2006) Medline Abstract; PDB files 2B3V and 2B3U
		E. Enemark and L. Joshua-Tor Mechanism of DNA translocation in a replicative hexameric helicase Nature 442 270-275 (2006). Medline Abstract;
		Feldman AR, Lee J, Delmas B, Paetzel M. Crystal structure of a novel viral protease with a serine/lysine catalytic dyad mechanism. J. Mol Biol. 19 1378-89 (2006) Medline Abstract; PDB file 2GEF
		B. Ford, V. Hornak, H. Kleinman and N. Nassar. Structure of a transient intermediate for GTP hydrolysis by ras. Structure 14 427-36 (2006). Medline Abstract; PDB files 1ZVQ and 1ZW6
		Gallager DT, Smith NN, KIM SK, Heroux A, Robinson H and Reddy PT. Structure of the Class IV Adenylyl Cyclase Reveals a Novel Fold. J Mol Biol. (2006). Medline Abstract; related PDB file 2FJT
		P. Haenzelmann, H. Schindelin, H. Binding of 5'-GTP to the C-terminal FeS cluster of the radical S-adenosylmethionine enzyme MoaA provides insights into its mechanism Proc.Natl.Acad.Sci.USA 103 6829-6834 (2006). Medline Abstract; PDB files 2FB2 and 2FB3
		Q. Huai, Y. Sun, H. Wang, D. Macdonald, R. Aspiotis, H. Robinson, Z. Huang and H. Ke. Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase. J Med Chem. 49 1867-1873. (2006). Medline Abstract; PDB files 2FM0 and 2FM5
		Y. Huang, J. Fang, M.T. Bedford, Y. Zhang, R.M. Xu Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A Science 312 748-751 (2006) Medline Abstract; PDB files 2GF7 and 2GFA
		E.Y. Kim , N. Schrader, B. Smolinsky, C. Bedet, C. Vannier, G. Schwarz and H. Schindelin H. Deciphering the structural framework of glycine receptor anchoring by gephyrin. EMBO J. 25 1385-95 (2006). Medline Abstract; PDB files 2FU3 and 2FTS
		H. Kleinman, B. Ford, J. Keller, N. Carpino and N. Nassar. Crystallization and initial crystal characterization of the C-terminal phosphoglycerate mutase homology domain of Sts-1. Acta Cryst. F62 218-220 (2206). Medline Abstract;
		S.H. Lawrence, K.B. Luther, H. Schindelin, J.G.Ferry, Structural and Functional Studies Suggest a Catalytic Mechanism for the Phosphotransacetylase from Methanosarcina thermophila J. BACTERIOL. 1881143-1154 (2006). Medline Abstract; PDB files 2AF3 and 2AF4
		T. C. Mallett, J. R. Wallen, P. A. Karplus, H. Sakai, T. Tsukihara, and Al Claiborne Structure of Coenzyme A-Disulfide Reductase from Staphylococcus aureus at 1.54 Å Resolution Biochemistry, 45 (38), 11278 -11289 (2006). Medline Abstract; PDB files
		A. Nagpal , M.P. Valley, P.F. Fitzpatrick, A.M. Orville. Crystal structures of nitroalkane oxidase: insights into the reaction mechanism from a covalent complex of the flavoenzyme trapped during turnover. Biochemistry 45 1138-50 (2006). Medline Abstract; PDB files 2C0U and 2C12
		F.E. Reyes-Turcu, J.R. Horton, J.E. Mullally, A. Heroux, X. Cheng and K.D. Wilkinson. The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin Cell 124 1197-1195 (2006). Medline Abstract; PDB file 2G43 and 2G45

		I.C. Schoenhofen, V.V. Lunin, J.P. Julien, Y.Li, E. Ajamian, A. Matte, M. Cygler, J.R. Brisson, A. Aubry, S.M. Logan, S. Bhatia, W.W. Wakarchuk, N.M. Young, Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudoaminic Acid, an Essential Flagellar Modification in Helicobacter pylori J Biol Chem. (2006) Medline Abstract; PDB file 2FN6
		T.J. Sullivan, J.J. Truglio, M.E. Boyne, P. Novichenok, X. Zhang, C. Stratton, H.J. Li, T. Kaur, A. Amin, F. Johnson, R.A. Slayden, C. Kisker, and P.J. Tonge. High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains of Mycobacterium tuberculosis ACS Chem.Biol. 1 43-53 (2006) Medline Abstract; PDB files 2B35 , 2B36 and 2B37
		G. Tian, S. Xiang, R. Noiva, W.J. Lennarz, H. Schindelin. The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites. Cell 124 61-73 (2006) Medline Abstract; PDB file 2B5E
		L.W. Tremblay, D. Dunaway-Mariano, K. Allen Structure and Activity Analyses of Escherichia Coli K-12 Nagd Provide Insight Into the Evolution of Biochemical Function in the Haloalkanoic Acid Dehalogenase Superfamily Biochemistry 45 1183-1193 (2006). Medline Abstract; PDB file 2C4N
		J.J. Truglio, E. Karakas, B. Rhau, H. Wang, M.J. DellaVecchia, B. Van Houten, B. and Kisker. Structural basis for DNA recognition and processing by UvrB. Nat.Struct.Mol.Biol. 13 . 360-4 (2006). Medline Abstract; PDB file 2FDC
		A.P. Vandemark, M. Blanksma, E. Ferris, A. Heroux, C.P. Hill, T. Formosa The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition. Mol Cell. 22 363-74 (2006). Medline Abstract; PDB files 2GCL and 2GCJ
		J. Wally, P.J. Halbrooks, C. Vonrhein, M.A Rould, S.J. Everse, A.B. Mason, Buchanan S.K. The crystal structure of iron-free human serum transferrin provides insight into inter-lobe communication and receptor binding. J Biol Chem. (2006). Medline Abstract; PDB files 2HAV and 2HAU RapiData2004
		S. Xiang, E.Y. Kim, J.J. Connelly, N. Nassar, J. Kirsch, J. Winking, G. Schwarz, H. Schindelin. The Crystal Structure of Cdc42 in Complex with Collybistin II, a Gephyrin-interacting Guanine Nucleotide Exchange Factor J.Mol.Biol. 359 35-46 (2006). Medline Abstract; PDB file 2DFK
	2005
		J. C. Amor, J. Swails, C. R. Roy, H. Nagai, A. Ingmundson, X. Cheng, R. A. Kahn The Structure of Ralf, an Arf Guanine Nucleotide Exchange Factor from Legionella Pneumophila, Reveals the Presence of a CAP Over the Active Site J Biol Chem. 80 1392-400 (2005) Medline Abstract; PDB files 1XSZ and 1XT0
		T. C. Auperin, G. R. Bolduc, M. J. Baron, A. Heroux, D. J. Filman, L. C. Madoff, J. M. Hogle Crystal Structure Of The N-Terminal Domain Of Group B Streptococcus C Protein J Biol Chem. 280 8245-52 (2005) Medline Abstract; PDB file 1YWM
		K. S. Champagne, M. Sissler, Y. Larrabee, S. Doublie, C. S. Francklyn Activation of the hetero-octameric ATP phosphoribosyl transferase through subunit interface rearrangement by a tRNA synthetase paralog. J Biol Chem. 280 34096-104 (2005) Medline Abstract; PDB file 1Z7M
		P. Cherepanov, A.L. Ambrosio, S. Rahman, T. Ellenberger, A. Engelman Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75. Proc Natl Acad Sci U S A. (2005) Medline Abstract; PDB file 2B4J
		P. A. Davison, H. L. Schubert, J. D. Reid, C. D. Iorg, A. Heroux, C. P. Hill, and C. N. Hunter Structural and Biochemical Characterization of Gun4 Suggests a Mechanism for Its Role in Chlorophyll Biosynthesis Biochemistry 44 7603 - 7612 (2005) Medline Abstract; PDB files 1Z3X and 1Z3Y
		B. Ford, K. Skowronek, S. Boykevisch, D. Bar-Sagi and N. Nassar. Structure of the G60A mutant of Ras: implications for the dominant negative effect. J Biol Chem. 280 25697-705 (2005). Medline Abstract; PDB file
		J.R. Horton, K. Sawada, M. Nishibori, X. Cheng Structural basis for inhibition of histamine N-methyltransferase by diverse drugs. J Mol Biol. 353 334-44 (2005) Medline Abstract; PDB files 2AOX, 2AOW, 2AOT, 2AOV and 2AOU
		E. Karakas, H. L. Wilson, T. N. Graf, S. Xiang, S. Jaramillo-Busquets, K. V. Rajagopalan, C. Kisker Structural insights into sulfite oxidase deficiency. J Biol Chem. 280 33506-15 (2005) Medline Abstract; PDB files 2A99, 2A9A, 2A9B, 2A9C, and 2A9D
		J.B. Ma , Y.R. Yuan, G. Meister, Y. Pei, T. Tuschl, D.J. Patel Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature 434 666-70 (2205) Medline Abstract; PDB file 1YTU
		H.C. Hsu, B. Stillman, R.M. Xu Structural Basis for Origin Recognition Complex 1 Protein-Silence Information Regulator 1 Protein Interaction in Epigenetic Silencing Proc.Natl.Acad.Sci.USA 102 8519-24 (2005) Medline Abstract; PDB file 1ZBX
		F. V. Rivas, N. H. Tolia, J. J. Song, J. P. Aragon, J. Liu, G. J. Hannon, L. Joshua-Tor Purified Argonaute2 and an Sirna Form Recombinant Human Risc. Nat.Struct.Mol.Biol. 12 340-9 (2005) Medline Abstract; PDB files 1Z25 and 1Z26
		Suryadi, J., Tran, E. J., Maxwell, E. S., Brown II, B. A Methanocaldococcus Jannaschii Multifunctional L7Ae RNA-Binding Protein Reveals an Induced-Fit Interaction with the Box C/D Rnas. Biochemistry 44 9657 (2005) Medline Abstract; PDB files 1XBI
		Y. Tie, P.I. Boross, Y.F. Wang, L. Gaddis, F. Liu, X. Chen, J. Tozser, R.W. Harrison, I.T. Weber. Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. Febs J. v272 pp. 5265-5277 (2005) Medline Abstract; PDB files 2AOF and 2AOH
		N. H. Tolia, E. J. Enemark, B. K. Sim, L. Joshua-Tor Structural Basis for the Eba-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium Falciparum. Cell 122 183 (2005) Medline Abstract; PDB file 1ZRL
		J. J. Truglio, B Rhau, D. L. Croteau, L. Wang, M. Skorvaga , E. Karakas, M. J. Dellavecchia, H. Wang, B. Van Houten, C. Kisker Structural insights into the first incision reaction during nucleotide excision repair. EMBO J. 24 885-894 (2005) Medline Abstract; PDB files 1YD0 -1YD6 and 1YCZ
		J. Wang, K. Stieglitz, E. R. Kantrowitz Metal Specificity is Correlated with Two Crucial Active Site Residues in Escherichia Coli Alkaline Phosphatase. Biochemistry 44 8378 (2005) Medline Abstract; PDB files 1Y7A and 1Y6V
	2004
		A. S. Auster, L. Joshua-Tor The DNA-binding domain of human papillomavirus type 18 E1. Crystal structure, dimerization, and DNA binding. J. Biol. Chem. 279 3733-3742 (2004) Medline Abstract; PDB files 1R9W
		L. G. Brieba, B. F. Eichman, R. J. Kokoska, S. Doublie, T. A. Kunkel, T. Ellenberger Structural Basis for the Dual Coding Potential of 8-Oxoguanosine by a High-Fidelity DNA Polymerase. Embo J. 23 3452 (2004) Medline Abstract; PDB files 1TK0, 1TKD and 1TK8
		T. T. Caradoc-Davies, S. M. Cutfield,I. L. Lamont, J. F. Cutfield Crystal Structures of escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium J. Biol. Chem. 337 337-354 (2004) Medline Abstract; PDB file 1SK4
		Dong A, Zhou L, Zhang X, Stickel S, Roberts RJ, Cheng X. Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions. Biol. Chem. 385 373-379 (2004) Medline Abstract; PDB files 1SVU
		G. Gopalan, Z. He, Y. Balmer, P. Romano, R. Gupta, A. Heroux, B. B. Buchanan, K. Swaminathan, S. Luan Structural analysis uncovers a role for redox in regulating FKBP13, an immunophilin of the chloroplast thylakoid lumen. Proc Natl Acad Sci U S A. 10113945-50 (2004) Medline Abstract; PDB files 1U79
		R. Guan, E. L. Malchiodi, W. Qian, P. Schuck, R. A. Mariuzza Crystal Structure of the C-Terminal Peptidoglycan-Binding Domain of Human Peptidoglycan Recognition Protein Ialpha J.Biol.Chem. 279 31873-82 (2004) Medline Abstract; PDB files 1RXY
		P. Haenzelmann, H. Schindelin Crystal Structure of the S-Adenosylmethionine-Dependent Enzyme Moaa and its Implications for Molybdenum Cofactor Deficiency in Humans Proc.Nat.Acad.Sci.USA 101 12870 (2004) Medline Abstract; PDB files 1TV7 and 1TV8
		J. R. Horton, G. Ratner, N. Banavali, N. Huang, V. E. Marquez, A. D. Mackerell, X. Cheng Caught in the Act: Visualization of an Intermediate in the DNA Base-Flipping Pathway Induced by HhaI Methyltransferase Nucleic Acids Res. 32 3877 (2004) Medline Abstract; PDB files 1SKM
		P.P. Iyer, S.H. Lawrence, K.B. Luther, K.R. Rajashankar, H.P. Yennawar, J.G. Ferry and H. Schindelin Crystal Structure of Phosphotransacetylase from the Methanogenic Archaeon Methanosarcina thermophila Structure 12 559-567 (2004) Medline Abstract; PDB files 1QZT
		B. Mahalingam, Y.-F. Wang, P. I. Boross, J. Tozser, J. M. Louis, R. W. Harrison, I. T. Weber Crystal Structures of HIV Protease V82A and L90M Mutants Reveal Changes in the Indinavir-Binding Site Eur.J.Biochem. 271 1516 (2004) Medline Abstract; PDB files 1SDU 1SDT and 1SDV
		V. Reiland, R. Gilboa, A. Spungin-Bialik, D. Schomburg, Y. Shoham, S. Blumberg, G. Shoham Binding of Inhibitory Aromatic Amino Acids to Streptomyces Griseus Aminopeptidase Acta Crystallogr., Sect.D 60 pp. 1738 (2004) Medline Abstract; PDB files 1TF8
		M. K. Safo, F. N. Musayev, S. Hunt, M. Di Salvo, N. Scarsdale, V. Schirch Crystal Structure of the Pdxy Protein from Escherichia Coli J.Bacteriol. 186 8074 (2004) Medline Abstract; PDB files 1TD2
		K. Sawada, Z. Yang, J. R. Horton, R. E. Collins, X. Zhang, X. Cheng Structure of the Conserved Core of the Yeast Dot1P, a Nucleosomal Histone H3 Lysine79 Methyltransferase J. Biol. Chem. 279 43296-43306 (2004) Medline Abstract; PDB files 1U2Z
		H. Shi, O. Cordin, C. M. Minder, P. Linder, R.-M. Xu Crystal Structure of the Human ATP-Dependent Splicing and Export Factor Uap56 Proc.Natl.Acad.Sci.USA 101 17628-33 (2004) Medline Abstract; PDB files 1XTK, 1XTJ and 1XTI
		N. Smith, M. Mayhew, M. J. Holden, H. Kelly, H. Robinson, A. Heroux, V. L. Vilker, D.T. Gallagher Structure of C73G putidaredoxin from Pseudomonas putida Acta Crystallogr D Biol Crystallogr. 60 816-22 (2004) Medline Abstract; PDB files 1R7S
		J. J. Truglio, D. L. Croteau, M. Skorvaga, M. J. DellaVecchia, K. Theis, B. S. Mandavilli, B. Van Houten, C. Kisker Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair. EMBO J. 23 2498-509 (2004) Medline Abstract; PDB files 1T5l
		K. K. Woods, T. Maehigashi, S. B. Howerton, S. Tannenbaum, L. D. Williams High-resolution structure of an extended A-tract: [d(CGCAAATTTGCG)]2. J Am Chem Soc. 126 15330-1 (2004) Medline Abstract; PDB files 1S2R
		Yang Z, Shipman L, Zhang M, Anton BP, Roberts RJ, Cheng X. Structural characterization and comparative phylogenetic analysis of E. coli HemK, a protein (N5)-glutamine methyltransferase. J. Mol. Biol. 340 695-706 (2004) Medline Abstract; PDB files 1T43
		Yernool D, Boudker O, Jin Y, Gouaux E. Structure of a glutamate transporter homologue from Pyrococcus horikoshii. Nature 431 811-8. (2004) Medline Abstract; PDB file 1XFH
	2003
		E. Freisinger, A. Fernandes, A.P. Grollman, C. Kisker, Crystallographic characterization of an exocyclic DNA adduct: 3,N4-etheno-2'-deoxycytidine in the dodecamer 5'-CGCGAATTepsilonCGCG-3'. J. Mol. Biol. 13 685-97 (2003). Medline Abstract; PDB file 1N5C
		Q. Huai, Y. Sun, H. Wang, L. S. Chin, L. Li, H. Robinson, H. Ke Crystal Structure Of Dj-1/Rs and Implication On Familial Parkinson'S Disease FEBS Lett. 549 171-175 (2003) Medline Abstract; PDB files 1Q2Uand 1PS4
		R. Jin, T. G. Banke, M. L. Mayer, S. F. Traynelis, E. Gouaux Structural Basis for Partial Agonist Action at Ionotropic Glutamate Receptors Nat.Neurosci. 6 803-810 (2003) Medline Abstract; PDB files 1MQJ
		A Kilshtain-Vardi, M Glick, H Greenblatt, A Goldblum, G. Shoham Refined Structure of Bovine Carboxypeptidase A at 1.25 Angstrom Resolution Acta Cryst. D59 323-333 (2003) Medline Abstract; PDB files 1ML4
		J. Liu, J. Dai, M. Lu. Zinc-Mediated Helix Capping in A Triple-Helical Protein. Biochemistry 42: 5657-5664 (2003) Medline Abstract; PDB files 1JCC
		J. R. Min, Q. Feng, Z. H. Li, Y. Zhang, R. M. Xu Structure of the Catalytic Domain of Human Dot1L, a Non-Set Domain Nucleosomal Histone Methyltransferase Cell 112 711-723 (2003) Medline Abstract; PDB files 1NW3
		J. R. Min, Y. Zhang, R.-M. Xu Structural Basis For Specific Binding Of Polycomb Chromodomain To Histone H3 Methylated At K27 Genes Dev. 17 1823 (2003) Medline Abstract; PDB files 1PFB
		M.J. Rudolph, J. L. Johnson, K.V. Rajagopalan, C. Kisker The 1.2 A structure of the human sulfite oxidase cytochrome b(5) domain Acta Cryst. D59 1183-91 (2003) Medline Abstract; PDB files 1MJ4
		M. J. Rudolph, M. M. Wuebbens, O. Turque, K. V. Rajagopalan, H. Schindelin Structural Studies of Molybdopterin Synthase Provide Insights Into its Catalytic Mechanism J.Biol.Chem. 278 14514 (2003) Medline Abstract;PDB files 1NVI
		N. Schrader, K. Fischer, K. Theis, R.R. Mendel, G. Schwarz, C. Kisker The crystal structure of plant sulfite oxidase provides insights into sulfite oxidation in plants and animals Structure, 11 1251-1263. (2003) Medline Abstract;PDB files 1OGP
		H. Shi, R.-M. Xu Crystal Structure of the Drosophila Mago Nashi-Y14 Complex . Genes Dev. 17, 971 (2003) Medline Abstract; PDB files 1OO0
		A. Soares, D. Caspar, E. Weckert, A. Heroux, K. Holzer, K. Schroer, J. Zellner, D. Schneider, W. Nolan, R. Sweet. Three-beam Interference is a Sensitive Measure of the Efficacy of Macromolecular Refinement Techniques. Acta Cryst. D59 1716-1724 (2003)
		V. Solomon, A. Teplitsky, G. Golan, R. Gilboa, V. Reiland, S. Shulami, S. Moryles, G. Zolotnitsky, Y. Shoham, G. Shoham he High-Resolution Crystal Structure of Ixt6, a Thermophilic, Intracellular Xylanase from G. Stearothermophilus To be Published PDB files 1N82
		J. Song, J. Liu, N. Tolia, J. Schneiderman, S. Smith, R. Martienssen, G. Hannon, L. Joshua-Tor. The Crystal Structure of the Argonaute2 PAZ Domain Reveals an RNA Binding Motif in RNAi Effector Complexes. Nat. Struct. Biol. 10 1026-1032. (2003) Medline Abstract; PDB files 1R6Z
		J.J. Truglio, K. Theis, Y. Feng, R. Gajda, C. Machutta, P.J. Tonge, C. Kisker Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis J. Biol. Chem, 43 42352-60 (2003)
		P. Wu, C. Qiu, A. Sohail, X. Zhang, A. S. Bhagwat, X. Cheng Mismatch Repair in Methylated DNA. Structure and Activity of the Mismatch-Specific Thymine Glycosylase Domain of Methyl-Cpg-Binding Protein Mbd4 J. Biol.Chem. 278 5285 (2003) Medline Abstract; PDB files 1NGN
		Y. Xiong, F. Li, J. Wang, A. M.Weiner, T. A. Steitz Crystal Structures Of An Archaeal Class I Cca-Adding Enzyme and Its Nucleotide Complexes Mol.Cell 12 1165 (2003) Medline Abstract; PDB files 1R8A and 1R8B and 1R89
		X.-L. Yang, F. J. Otero, R. J. Skene, D. E. Mcree, P. Schimmel, L. Ribas De Pouplana Crystal Structures That Suggest Late Development Of Genetic Code Components For Differentiating Aromatic Side Chains Proc. Nat. Acad. Sci. USA 100 15376 (2003) Medline Abstract;PDB file 1Q11
		Z.Yang, J.R. Horton, L. Zhou, X.J. Zhang, A. Dong, X. Zhang, S.L. Schlagman, V. Kossykh, S. Hattman, X. Cheng. Structure of the bacteriophage T4 DNA adenine methyltransferase. Nat. Struct. Biol. 10 849-55 (2003) Medline Abstract; PDB files 1QOT and 1QSO
		X. Zhang, X. Cheng Structure of the Predominant Protein Arginine Methyltransferase Prmt1 and Analysis of its Binding to Substrate Peptides Structure 11 509 (2003) Medline Abstract; PDB files 1ORI and 1ORH
	2002
		K. Bateman, E. Brownie, W. Wolodko, M. Fraser Structure of the Mammalian CoA Transferase from Pig Heart Biochemistry 417 14455-14462, (2002) Medline Abstract; PDB file 1M3E
		A.F. Bell , Y. Feng, H. A. Hofstein, S. Parikh S, Wu J, Rudolph MJ, Kisker C, Whitty A, Tonge PJ. Stereoselectivity of enoyl-CoA hydratase results from preferential activation of one of two bound substrate conformers. Chem Biol. 9 1247-55. (2002) Medline Abstract; PDB files 1MJ3
		E. Enemark, A. Stenlund, L. Joshua-Tor Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex EMBO J, 21 1487-1496 (2002) Medline Abstract; PDB files 1KSY and 1KSX
		M. Himmel, S. Gourinath, L. Reshetnikova, Y. Shen, G. Szent-Gyorgyi, C. CohenCrystallographic Findings on the Internally Uncoupled and Near-Rigor States of Myosin: Further Insights Into the Mechanics of the Motor Proc.Nat.Acad.Sci.US, 99 12645 (2002) Medline Abstract; PDB file 1L2O
		R. Gilboa, D. Zharkov, G. Golan, A. Fernandes, S. Gerchman, E. Matz, J. Kycia, A. Grollman, G. Shoham Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA J. Biol. Chem. 277 19811-6 (2002) Medline Abstract; PDB file 1K82
		B. Hall, D. Bar-Sagi, N. Nassar The Structural basis for the transition from Ras.GTP to Ras.GDP Proc. Natl. Acad. Sci. USA. 99 12138 (2002) Medline Abstract; PDB files 1LF5 and 1LF0
		I. Hayashi, K. Vuori, R. Liddington The focal adhesion targeting (FAT) domain of focal adhesion kinase is a four-helix bundle that binds paxillin Nat. Struct. Biol. 9 101-109 (2002) Medline Abstract; PDB file 1K40
		D. M. Himmel, S. Gourinath, L. Reshetnikova, Y. Shen, A. G. Szent-Gyorgyi, C. Cohen Crystallographic Findings on the Internally-uncoupled and Near-rigor States of Myosin: Further Insights into the Mechanics of the Motor Proc. Natl. Acad. Sci. USA 99 12645-12650 (2002) Medline Abstract; PDB file 1L2O
		T. Messick, N. Chmiel, M. Golinelli, M. Langer, L. Joshua-Tor, S. David Noncysteinyl coordination to the [4Fe-4S]2+ Cluster of the DNA Repair Adenine Glycosylase MutY introduced via Site-Directed Mutagenesis. Structural Characterization of an Unusual Histidinyl Coordinated Cluster Biochemistry 41 3931-3942 (2002) Medline Abstract; PDB file 1KQJ
		J. R. Min, X. Zhang, X. D. Cheng, S. I. S. Grewal, R.-M. Xu Structure of the Set Domain Histone Lysine Methyltransferase Clr4 Nat.Struct.Biol. 9 828 (2002) Medline Abstract; PDB file 1MVX
		J. Truglio, K. Theis, S. Leimkuhler, R. Rappa, K. Rajagopalan, C. Kisker Crystal Structures of the Active and Alloxanthine-Inhibited Forms of Xanthing Dehydrogenase from Rhodobacter Capsulatus Structure 10 115-125 (2002) Medline Abstract; PDB file 1JRO
		D. van Aalten, W. Crielaard, K. Hellingwerf, L. Joshua-Tor Crystal structure of the photoactive yellow protein reconstituted with caffeic acid at 1.16 Å resolution Acta Crys. D58 585-590 (2002) Medline Abstract; PDB file 1KOU
		D.M. van Aalten, A. Hacker, J. Hendricks, KJ. Hellingwerf, L. Joshua-Tor, W. Crielaard Engineering photocycle dynamics. Crystal structures and kinetics of three photoactive yellow protein hinge-bending mutants. J Biol Chem. 22 6463-8 (2002) Medline Abstract; PDB files 1GSV, 1GSW and 1GSX
		Z. Zhang, M. Hayashi, O. Merkel, B. Stillman, R. Xu Structure and Function of the BAH-containing Domain of Orc1p in Epigenetic Silencing EMBO J. 21 4600-4611 (2002) Medline Abstract; PDB file 1M4Z
		D. Zharkov, G. Golan, R. Gilboa, A. Fernandes, S. Gerchman, J. Kycia, R. Reiger, A. Grollman, G. Shoham Structural analysis of Escherichia coli endonuclease VIII: its covalent reaction intermediate EMBO J. 21 789-800, (2002) Medline Abstract; PDB files 1K3W and 1K3X
	2001
		J.A. Carrodeguas, K. Theis, D.F. Bogenhagen and C. Kisker, Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase g, Pol gB, functions as a homodimer. Mol. Cell 7 43-54 (2001) Medline Abstract; PDB files 1G5H and 1G5I
		A. Dong, J.A. Yoder, X. Zhang, L. Zhou, T.H. Bestor and X. Cheng, Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA. Nucleic Acid Res. 29 439-448 (2001) Medline Abstract; Full Text; PDB file 1G55
		H. Feinberg, D. A. Mitchell, K. Drickamer, W. I. Weis Structural Basis for Selective Recognition of Oligsaccharides by Dc-Sign and Dc-Signr. Science 294 2163 (2001) Medline Abstract; Full Text; PDB file 1K9J
		D. Himmel Structural Studies on the Myosin Molecular Motor: A) Evidence for a "Detached" ATP State, and B) Comparison of Calcium-Bound and Calcium-Free Regulatory Domains University Microfilms International, February, (2001)
		J. Horton, K. Sawada, M. Nishibori, X. Zhang, X. Cheng Two Polymorphic Forms of Human Histamine Methyltransferase: Structural, Thermal, and Kinetic Comparisons Structure 9 837-849 (2001) Medline Abstract; PDB file 1JQE
		S. Howerton, C. Sines, D. Vanderveer, L. Williams Locating Monovalent Cations in the Grooves of B-DNA Biochemistry 40 10023-10031 (2001) Medline Abstract; PDB file 1JGR
		M. Lake, M. Wuebbens, K. Rajagopalan, H. Schindelin Mechanism of Ubiquitin Activation Revealed by the Structure of a Bacterial MoeB-MoaD Complex Nature 414 325-329 (2001) Medline Abstract; PDB file 1JWA and 1JWB
		J. Madrazo, J. H. Brown, S. Litvinovich, R. Dominguez, S. Yakovlev, L. Medved, C. Cohen Crystal Structure of the Central Region of Bovine Fibrinogen (E5 Fragment) at 1.4 Angstroms Resolution Proc. Nat. Acad. Sci.USA 98 11967 (2001) Medline Abstract; PDB file 1JY3
		J. Min, J. Landry, R. Sternglanz and R.-M. Xu, Crystal structure of a SIR2 Homolog-NAD Complex. Cell 105 269-279 (2001) Medline Abstract; PDB file 1ICI
		M.J. Rudolph, M.M. Wuebbens, K.V. Rajagopalan and H. Schindelin, Crystal structure of molybdopterin synthase and its evolutionary relationship toubiquitin-activation. Nature Struct. Biol. 8 42-46 (2001) Medline Abstract; PDB files 1FM0 and 1FMA
		G. Schwarz, N. Schrader, R. Mendel, H. Hecht, H. Schindelin Crystal Structures of Human Gephyrin and Plant Cnx1 G Domains-Comparative Analysis and Functional Implications J. Mol. Biol. 312 405-418 (2001) Medline Abstract; PDB file 1JLJ
		J. Seely, C. Brown, G. Holland, J. Hanser, J. Wise, J.Weaver, R. Korde, R. Viereck, R. Grubb, D. Judge Calibration of an Extreme Ultraviolet Transmission Grating Spectrometer using Synchrotron Radiation Appl. Optics-OT 40 1623 (2001)
		S. Xiang, J. Nichols, K.V. Rajagopalan and H. Schindelin, The crystal structure of Escherichia coli MoeA and its relationship to the multifunctional protein gephyrin. Structure 9 299-310 (2001) PDB files 1G8L and 1G8R
		T. Yoon, S. Tétreault, H. Bosshard, R. Sweet, J. Sygusch Mosaic spread analysis of Canadian advanced protein crystallization experiment on the Russian space station, Mir J. Cryst. Growth 232, 520-535 (2001)
	2000
		M.W. Lake, C.A. Temple, K.V. Rajagopalan and H. Schindelin, The crystal structure of the Escherichia coli MobA protein provides insight into molybdopterin guanine dinucleotide biosynthesis. J. Biol. Chem. 275 40211-40217 (2000). Medline Abstract; Full Text; PDB files 1FR9 and 1FRW
		T.J. Boggon, J.R. Helliwell, R.A. Judge, A. Olczak, D.P. Siddons, E.H. Snell and V. Stojanoff, Synchrotron X-ray reciprocal-space mapping, topography and diffraction resolution studies of macromolecular crystal quality. Acta Cryst. D 56, 868-880 (2000).
		H. Feinberg, D. A. Mitchell, K. Drickamer, W. I. Weis Structural Basis for Selective Recognition of Oligsaccharides by Dc-Sign and Dc-Signr. Science 294 2163 (2001) Medline Abstract; PDB file 1K9J
		H.K. Li, C. Temple, K.V. Rajagopalan and H. Schindelin, The 1.3 Å crystal structure of Rhodobacter sphaeroides dimethylsulfoxide reductase reveals two distinct molybdenum coordination environments. J. Am. Chem. Soc. 122 7673-7680 (2000). Medline Abstract; PDB file 1EU1
		G. Vilkaitis, A. Dong, E. Weinhold, X. Cheng and S. Kilmasauskas, Functional roles of the conserved threonine-250 in the target recognition domain of HhaI DNA methyltransferase. J. Biol. Chem. 275 38722-38730 (2000). Medline Abstract; Full Text; PDB file 1FJX
		C.C. Sines, L. McFail-Isom, S.B. Howerton, D. VanDerveer and L.D. Williams, Cations mediate B-DNA Conformational Heterogeneity. J. Am. Chem. Soc. 122 11048-11056 (2000). PDB file 1FQ2
		K. Theis, M. Skorvaga, M. Machius, N. Nakagawa, B. Van Houten and C. Kisker, The nucleotide excision repair protein UvrB, a helicase-like enzyme with a catch. Mutation Res. 460 277-300 (2000). Medline Abstract
		J.R. Horton and X. Cheng, PvuII endonuclease contains two calcium ions in active sites. J. Mol. Biol. 300 1049-1056 (2000). Medline Abstract; PDB file 1EYU
		X. Zhang, L. Zhou and X. Cheng, Crystal structure of the conserved core of protein arginine methyltransferase PRMT3. Embo J. 19 3509-3519 (2000). Medline Abstract; PDB file 1F3L
		M.M. Wuebbens, M.T. Liu, K. Rajagopalan and H. Schindelin, Insights into molybdenum cofactor deficiency provided by the crystal structure of the molybdenum cofactor biosynthesis protein MoaC. Structure 8 709-718 (2000). Medline Abstract; PDB files 1EKR and 1EKS
		E.J. Enemark, Y.G. Chen, D.E. Vaughn, A. Stenlund and L. Joshua-Tor, Crystal structure of the DNA binding domain of the replication initiation protein E1 from papillomavirus. Mol. Cell 6 149-158 (2000). Medline Abstract; PDB file 1F08
		Z. Zhang, R. Zhang, A. Joachimiak, J. Schlessinger, and X. Kong, Crystal structure of human stem cell factor: implication for stem cell factor dimerization and activation. Proc Natl. Acad. Sci. USA 97, 7732-7737 (2000). Medline Abstract; Full Text; PDB file 1EXZ
		J. Jiang, D.S. Horowitz and R.-M. Xu, Crystal structure of the functional domain of the splicing factor Prp18. Proc. Natl. Acad. Sci. USA 97 3022-3027 (2000). Medline Abstract; Full Text; PDB file 1DVK
		M.T.W. Liu, M.W. Wuebbens, K.V. Rajagopalan and H. Schindelin, Crystal structure of the gephyrin-related molybdenum cofactor biosynthesis protein MogA from Escherichia coli. J. Biol. Chem. 275 1814-1822 (2000). Medline Abstract; Full Text; PDB files 1DI6 and 1DI7
		D.M.F. van Aalten, W. Crielaard, K.J. Hellingwerf and L. Joshua-Tor, Conformational substates in different crystal forms of the photoactive yellow protein - correlation with theoretical and experimental flexibility. Protein Sci. 9 64-72 (2000). Medline Abstract PDB file 1D7E
		Zharkov DO, Gilboa R, Yagil I, Kycia JH, Gerchman SE, Shoham G, Grollman AP. Role for lysine 142 in the excision of adenine from A:G mispairs by MutY DNA glycosylase of Escherichia coli. Biochemistry 3914768-78 (2000) Medline Abstract PDB files 1KG2 , 1KG3, 1KG5, 1KG6 and 1KG7
	1999
		K. Theis, P.J. Chen, M. Skorvaga, B. Van Houten and C. Kisker, Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair. EMBO J. 18 6899-6907 (1999) Medline Abstract Full Text; PDB files 1D9X and 1D9Z
		D.E. Vaughn, J. Rodriguez, Y. Lazebnik and L. Joshua-Tor, Crystal structure of the Apaf-1 caspase recruitment domain: an alpha-helical greek key fold for apoptotic signaling. J. Mol. Biol. 293 439-447 (1999) Medline Abstract PDB file 1CY5
		D.M.F. van Aalten, D. Erlanson, G.L. Verdine and L. Joshua-Tor, A structural snapshot of base-pair opening in DNA. Proc. Natl. Acad. Sci. USA 96 11809-11814 (1999). Medline Abstract; Full Text; PDB file 1CW9
		M.J. Stewart, S. Parikh, G. Xiao, P.J. Tonge and C. Kisker, Structural basis and mechanism of enoyl reductase inhibition by triclosan. J. Mol. Biol. 290 859-865 (1999) Medline Abstract PDB file 1QSG
		P.A. O'Farrell, F. Gonzalez, W. Zheng, S.A. Johnston and L. Joshua-Tor, Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cystein protease Structure Fold Des. 7 619-627 (1999) Medline Abstract PDB files 1CB5 and 2CB5
		J. Ding, M.K. Hayashi, A.R. Krainer and R.-M. Xu, Crystal structure of the two-RRM domain of hnRNP Al (UPl) complexed with single stranded telomeric DNA. Genes Dev. 13 1102-1115 (1999) Medline Abstract Full Text; PDB file 2UP1

		J. Jiang, Y. Zhang, A.R. Krainer and R.-M. Xu, Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein. Proc. Natl. Acad. Sci. USA 96 3572-3577 (1999) Medline Abstract; Full Text; PDB file 1P32
		R. Gilboa, A.J. Bauer and G. Shoham, Crystallization and preliminary crystallographic analysis of glyceraldehyd 3-phosphate dehydrogenase from Sacchromyces cerevisiae (bakers yeast). Acta Cryst. D Biol. Crystallogr. 54 1467-1470 (1998) Medline Abstract
		V. Stojanoff, D.P. Siddons, L. Monaco, P. Vekilov and F. Rosenberger, X-ray topography of tetragonal lysozyme grown by the temperature-controlled technique. Acta Cryst. D53 588-595 (1997)