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EC-NUMBER
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5.4.2.4
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ENZYME-NAME
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bisphosphoglycerate mutase
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ENZYME-SYSNAME
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In the direction shown, this enzyme is phosphorylated by 3-phosphoglyceroyl phosphate, to give phosphoenzyme and 3-phosphoglycerate. The latter is rephosphorylated by the enzyme to yield 2,3-bisphosphoglycerate, but this reaction is slowed by dissociation of 3-phosphoglycerate from the enzyme, which is therefore more active in the presence of added 3-phosphoglycerate. This enzyme also catalyses, slowly, the reactions of EC 3.1.3.13 (bisphosphoglycerate phosphatase) and EC 5.4.2.1 (phosphoglycerate mutase). Formerly EC 2.7.5.4.
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ENZYME-CLASS
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Isomerases Intramolecular transferases (mutases) Phosphotransferases (phosphomutases)
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SYNONYMS
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2,3-bisphosphoglycerate mutase;;
2,3-diphosphoglycerate mutase;;
2,3-diphosphoglycerate synthase;;
2,3-diphosphoglyceromutase;
>>more synonyms
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REACTION
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3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate [RN:R01662]
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PATHWAY
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EMP-PATHWAYS:
1,3-Bisphosphoglycerate--3-Phosphoglycerate,_Orthophosphate_Catabolism;
>>more EMP pathways
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KEGG-PATHWAYS:
Glycolysis / Gluconeogenesis;
>>more KEGG pathways
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GO_TERM
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GO:0004082:bisphosphoglycerate mutase activity
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ENZYME-COMMENT
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3-phospho-D-glycerate 1,2-phosphomutase
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