Greenspan D, Overby G, Feigal DW, MacPhail L, Miyasald S, Greenspan JS; International Conference on AIDS.

Int Conf AIDS. 1989 Jun 4-9; 5: 469 (abstract no. Th.B.P.320).

The Schools of Dentistry and Medicine, University of California, San Francisco, USA

OBJECTIVE: To describe the locations in the mouth where hairy leukoplakia (HL), and the various forms of candidiasis with their relative prevalence in a referral population to an Oral AIDS Clinic. METHODS: The Oral AIDS Epidemiology project initiated a uniform prospective set of data collection procedures for the oral complications of HIV in both community cohorts, AIDS clinics and the Oral AIDS Clinic. This analysis is based on the findings in the referral patients to the Oral AIDS Clinic. HL is biopsy proven in the majority of cases. Candidiasis is confirmed by KOH exam or cultures. The location of each lesion is sketched on a map of the mouth. RESULTS: Hairy leukoplakia was the most common lesion observed in 226 individuals. 87% of patients had involvement of the lateral (including extension to the ventral surfaces), and 29% the dorsum of the tongue. The buccal mucosa was less frequently involved, 3%, as was the soft palate (.4%). (No lesions were seen on the hard palate). Pseudomembranous candidiasis (thrush) was observed throughout the mouth in 106 patients, most commonly involving the tongue, 42% lateral 48% dorsum. The hard palate 20% and soft palate (19%) were also frequently observed, as was the buccal mucosa (15%). Erythematous candidiasis (n=66), easily overlooked with a flat red appearance, was most frequently seen on the hard palate (60%), soft palate (17%), and dorsum of the tongue (57%) where depappilation was a common finding. Angular cheilitis due to candida was observed in another 14 patients. CONCLUSIONS: Hairy leukoplakia although almost universally found on the lateral surface of the tongue also appears in the buccal mucosa. Pseudomembranous candidiasis occurs almost twice as often as the other manifestations of candidiasis and can affect almost any surface in the mouth. Erythematous candida is much more characteristic of the tongue and hard palate. Concurrent HL and candida was a common finding.

Publication Types:

• Meeting Abstracts

Keywords:

• Acquired Immunodeficiency Syndrome
• Candidiasis, Oral
• Cheilitis
• HIV Infections
• HIV Seropositivity
• Humans
• Leukoplakia, Hairy
• Longitudinal Studies
• Mouth
• Mouth Diseases
• Mouth Neoplasms
• Palate, Hard
• Prevalence
• epidemiology

Other ID:

• 00242789

UI: 102178330

From Meeting Abstracts