a, b, d, C
Non-agouti, dulite brown
Genes:

Car-2^b, Ce-2^a, Es-1^b, Es-3^c, Es-10^b, Gpd-1^b, Gpi-1^a, Gus^b, Hba^g, Hbb^d, Idh-1^b, Lv^a, Mod-1^a, Mup-1^a, Pep-3^b, Pgm-1^b, Trf^b
Hc⁰, H-2D^d, H-2K^d, Lyb-2^a, Lyt-1^a, Lyt-2^a, Lyt-3^b, Thy-1^b, Tla^c.

• Mammary tumors in old females. (680)

• 3-Methylcholanthrene induced brain tumors in only 3%. (404)
• In comparison with other inbred strains, DBA/2 is susceptible to Bittner, Friend S and Friend B viruses, relatively susceptible to Gross virus, and resistant to Vaccinia virus. (370)
• Benzo(a)pyrene induced more fibrosarcomas in C3H mice than in DBA/2 mice, and simultaneous application of 7, 8-benzoflavone caused a greater increase in tumor incidence in C3H mice; however, 1, 1, 1-trichloropropene-2, 3-oxide plus benzo(a)pyrene induced a higher incidence of fibrosarcomas in DBA/2 mice. (781)

• Intestinal volvulus in a small percentage. (140)
• Over 50% of males and females had dystrophic cardiac calcinosis in the myocardium and/or epicardium. (160)

• Relatively resistant to infection by Plasmodium berghei. (492)
• Susceptible to infection with Leishmania tropica, but no clinical signs of disease. (063)

• High interferon induction by Newcastle disease virus. (696)
• Antibody response to single-stranded DNA is low and response is controlled by an autosomal dominant gene regulated by sex hormones. (571)

• Aryl hydrocarbon hydroxylase increased only 20% by 3-methylcholanthrene. The “nonresponsive” Ah^d allele is present. (404,403)
• Gamma-aminobutyric acid binding was lower in DBA/2 than C57BL/6 cerebral cortex, hippocampus, striatum, and diencephalons. (739)
• Liver alcohol dehydrogenase activity is slightly lower, and liver alhehyde dehydrogenase much lower than C57BL/6. (299)
• Morphine decreased acetylcholine turnover rate in cerebral cortex. (561)

• Low plasma resting steroid levels, peak only briefly after stress. (398)

• Quickly develops an aversion to ethanol. (299)

• Susceptible to audiogenic seizures; susceptibility begins at 12-17 days, peaks at 21 days, then gradually declines with age. (646)
• Antithyroid drugs or radiothyroidectomy suppresses susceptibility to audiogenic seizures. Suitable as a model for testing anticonvulsants. (647, 421)
• Oral benzo(a)pyrene killed mice in 4 weeks due to pancytopenia. (737)
• 3-Methylcholanthrene was less toxic to DBA/2N primordial oocytes than to C57BL/6N oocytes. (447)
• More sensitive to toxic effects of chloroform than C57BL/6. (097)
• More sensitive to analgesic action of morphine than C57BL/6. (561)