Energy Citations Database

Bibliographic Citation

 
Document
For copies of Journal Articles, please contact the Publisher or your local public or university library and refer to the information in the Resource Relation field.
For copies of other documents, please see the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or Document Availability.
Title Prevention of 3-methylcholanthrene-induced fibrosarcomas in rats pre-inoculated with endogenous rat retrovirus
Creator/Author Fish, D.C. (Frederick Cancer Research Center, MD) ; Demarais, J.T. ; Djurickovic, D.B. ; Huebner, R.J.
Publication Date1981 Apr 01
OSTI IdentifierOSTI ID: 6769083
Other Number(s)CODEN: PNASA
Resource TypeJournal Article
Resource RelationProc. Natl. Acad. Sci. U.S.A. ; Vol/Issue: 78:4
Subject560305 -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987); ;3-METHYLCHOLANTHRENE-- TOXICITY;NEOPLASMS-- INHIBITION;VIRUSES-- INOCULATION; CARCINOGENESIS;IMMUNITY;RATS
Related SubjectANIMALS;AROMATICS;DISEASES;HYDROCARBONS;MAMMALS;MICROORGANISMS;ORGANIC COMPOUNDS;PARASITES;PATHOGENESIS;POLYCYCLIC AROMATIC HYDROCARBONS;RODENTS;VERTEBRATES
Description/Abstract Weanling Fischer 344 rats received a single intraperitoneal injection of a 1000-fold concentrated preparation of endogenous nontransforming rat retrovirus.^Ten days later, the rats were each given a single subcutaneous injection of 3-methylcholanthrene.^The rats inoculated with the endogenous rat retrovirus were significantly protected against the development of cancer, whereas uninoculated rats and rats given one of several murine tetroviruses or baboon retrovirus were not protected.
Country of PublicationUnited States
LanguageEnglish
FormatPages: 2526-2527
System Entry Date2001 May 13

Top