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Infectious Disease Pathogenesis
 Mouse Necropsy
  Necropsy Sheet
  Instruments and Fixatives
  Necropsy Terms
  1) Starter Kit
  2) First Incision
  3) Lymph Nodes, Mammary Glands
  4) Abdominal Cavity
  5) Urogenital System
  6) Intestines, Stomach, Spleen, Pancreas
  7) Liver 1
  8) Liver 2
  9) Kidneys
  10) Lungs
  11) Heart
  12) Brain
  References
 Veterinary Pathology



Comparative Medicine Branch

Virtual Mouse Necropsy

The Necropsy Dictionary: First Edition

By D.E. Devor and E.M. Parsoneault

ABCDEF, G, HI, J, KLMNOP, Q, R, S, T, U, V, W, X, Y, Z

A

abdomen; abdominal - cavity below the diaphragm containing abdominal tissues including the stomach, intestine, kidneys, spleen etc.

abscess - collection of dead inflammatory cells and live neutrophils, often with bacteria present

adhesion - sticking together of two or more tissues due to inflammation or trauma

anemia; anemic - animal appears pale; quality or quantity of blood is poor which occurs due to hemorrhage or to such conditions as large masses, leukemias, lymphomas, etc.

anopthalmia - no eyes or very small eyes that are difficult to see

anorexia; anorexic - lack of appetite or avoidance of food

anterior - refers to a structure being more in front than another structure in the body

ataxia; ataxic - miscellaneous incoordination

atelectic (in lungs) - airless condition such as a collapsed lung lobe, may also be noted as consolidation

atrophy; atrophic - marked decrease in size

autolysis; autolytic; autolyzed - rotting of cells after death of the animal

azygous - unpaired

B

biliary - pertaining to bile

bulbous - having a bulb shape

C

cachexia - malnutrition associated with carcinoma or other chronic condition

cachectic - the lack of appetite seen in cancer

calcareous, calciferous, calcification - all terms imply the appearance of calcium deposition (i.e. chalky, white, hard, and brittle)

calcinosis - condition of forming calcium deposit

calculus; calculi - stone in the kidney pelvis, gall bladder, urethra, bladder

caseous - purulent material in a more solid form

caudal (inferior) -refers to a structure being closer to the feet or the tail end of the body than another relative structure in the body

cirrhosis; cirrhotic - used to describe a fibrous condition of the liver

coagulation; coagulative - clotting

contralateral - refers to a structure on the opposite side of the body as the reference point

coronal (frontal) - longitudinal plane dividing the body into equal or unequal front and back parts

cortex; cortical - the outer layer of an organ

cranial (superior, rostral, head end) - refers to a structure being closer to the head or higher than another structure of the body

cross (transverse) - plane perpendicular to the longitudinal plane dividing the body parts into upper and lower segments

cyanotic; cyanosis - animal or tissue appears blue or gray due to lack of blood oxygenation

D

deep - refers to internal structures or structures further away from a body wall than another

degeneration; degenerative - similar to depletion but implies a decrease in function and form

dehydration - lack of fluid in cellular and interstitial spaces

depleted; depletion - used up, exhausted-looking: a qualitative/descriptive term rather than a diagnostic one

diaphragm; diaphragmatic - the muscle separating thoracic and abdominal cavities

distal - refers to a structure being further away from the median plane or the root of a limb than another structure in the limb

dorsal - refers to the top side

E

edema; edematous - fluid accumulation within tissues, esp. connective tissues

emaciation - no body fat

endometrium; endometrial - inner layer of the uterus, mucosa

enteric - pertaining to the intestines

enteritis - inflammation of the intestines

epiglottis; epiglottal - the flap of tissue which closes off the trachea when swallowing

epithelium; epithelial - pure cellular (nonvascular) layer covering any free surface (skin or tubular structures such as intestines, esophagus, uterus)

exudate - fluid which has seeped out of tissues or vessels due to injury, increased permeability of cells, or inflammation

F

fibrosis; fibrotic - when connective tissue becomes rigid and firm; nonelastic

follicle; follicular - sac, pouch; also a columnar depression or cavity

friable - brittle

fundus; fundic - the bottom or lowest part of a sac or hollow organ; term used most frequently referring to the stomach

fungating - literally, growing as a fungus would; also having a spongy texture

H

hemangioma; hemangiomatous - a lesion of the blood vessels

hemorrhage; hemorrhagic - uncontrolled or copious bleeding

hepatic - pertaining to the liver

hepatitis - inflammation of the liver

hepatomegaly - swelling or enlargement of the liver

hilis; pl. hili - the medial indentation in an organ (notably lymph nodes and kidney) where the efferent and afferent vessels enter and exit

hydrocephalic; hydrocephalus - swelling of the cranium either due to fluid build up within or around the brain

hyperemia (congestion) - congestion; pooling of blood

hyperplasia; hyperplastic - increase in cell number within an organ or tissue

hypertrophy - enlargement of an organ or cell; swelling due to increase in cell or organ size

hypotaxia; hypotaxic - poor or weak movements; disorientation

I

icteric; icterus - yellowed, may be due to bile or bilirubin accumulation

in situ - in place

in vitro - in tissue culture

in vivo - in the living animal

incisor - teeth used to cut or incise, as opposed to guarding

inflamed; inflammation - changes in tissues caused by injury or abnormal stimulation, chronic irritation (redness, heat, swelling, pain and sometimes loss of function)

interstitium; interstitial - the microscopic spaces within tissues

intussusception - the telescoping of intestine over a lesion

ipsilateral - refers to a structure on the same side of the body as the reference point

K

keratinization - thickening of the epidermis by overproduction of keratin, forming calluses

kyphosis; kyphotic - the hunched posture shown by animals in distress or pain

L

larynx, laryngeal - voice box

lateral - refers to a structure that is further away from the median plane than another structure

lethargic; lethargy - reluctance or inability to move or respond to stimuli

lordosis; lordotic - the typical posture shown by many animals in heat with the rump and tail elevated

M

medial - refers to a structure that is closer to the median plane than another structure in the body

median - the midline, longitudinal plane dividing the body into right/left halves

medulla; medullary - hindbrain, mostly concerned with motor and basic life support functions; also the inner or middle portions of an organ

meninges; meningial - lining of the brain and spinal cord

mesometrium; mesometrial - the membrane holding the uterine horns to the body wall

metastasis; metastases; metastatic - spreading of a cancer to a distant site usually through blood or lymph vessels

micropthalmia - small eyes

morbid - sick

moribund - near death

N

necrosis; necrotic; necrotizing - cell death

neoplasia; neoplastic - new growth or abnormal tissue growth

nephritis; nephritic - kidney inflammation

O

ocular - pertaining to the eyeball or eye socket

P

papilloma; papillomatous; papillary; papilla; papillae - wart-like growth with or without a stalk

pedunculated; peduncle - having a stalk

perforate - having holes

perineum; perineal - the area of the vulva/scrotum and the anal opening

periosteum; periosteal - the membrane surrounding bones

peritoneum; peritoneal - lining of the abdominal cavity

pharynx; pharyngeal - throat area containing openings to both the trachea and the esophagus

piloerection - hair appears ruffled or erect, doesn't lie down smoothly, often found in dehydrated, typical of malnourished and very sick animals who don't or can't groom.

pleura; pleural - membranes lining the chest cavity and lungs

polydipsia (dypsia) - excessive drinking

polyp; polypoid - usually a smooth rounded growth with some length of stalk, similar to a papilloma but generally arising from an internal tissue

polyuria - excessive urination

posterior - refers to structure being more in back than another structure in the body

prepuce; preputial - sheath that protects the penis

prolapse - protrusion or slippage of an organ or tissue from its normal location

proximal - refers to a structure being closer to the median plane or the root of a limb than another structure in the limb

pulmonary - pertaining to the lungs

purulent - descriptive term for what is found in most abscesses or pus-like discharges

pylorus; pyloric - terminal segment of the stomach ending at the duodenal junction

S

sagittal - the longitudinal plane dividing structures into left and right halves

scirrhous - hard, firm

sebaceous - usually refers to an oily or fatty secretion

septicemia; septicemic - systemic infection caused by microorganisms circulating in the blood; whole body infection

serum; serous - the clear tannish fluid that separates from whole blood

sessile - lesion/mass without a stalk connected to main tissue by a broad base

splenic - pertaining to the spleen

splenomegaly - marked enlargement of the spleen

stroma - connective tissue network of tumor or tissue

subcutaneous - beneath the skin

superficial - refers to structures on the external surface of the body or a structure closer to the external surface of the body than another

T

thrombus - fibrinous mass atached to endothelial tissue or blood vessel

V

ventral - refers to belly side of the body

vertebra; pl.vertebrae; vertebral - bones along the spinal cord

vesicle; vesicular - small liquid or gas filled sac

visceral - abdominal structure and organs

A   B   C   D   E   F  G   H   I   J   K   L   M   N   O   P   Q   R   S   T   U   V   W   X   Y   Z

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